ライフサイエンスコーパス: role for

1 Here we unveil a new role for 2-arachidonoylglycerol, the major CNS endocanna

2 g transcription, demonstrating an unexpected role for 3'-UTR sequences in transcriptional regulation.

3 nd 5-methylcytosine and reinforce a distinct role for 6mA as a gene-expression-associated epigenomic

4 Here, we identify a novel role for a central region component of the SC, SYP-4, in

5 he function, and discovered a new behavioral role for a genetically defined population of central ves

6 reated with DEN, and identifies an important role for ACC enzymes in redox regulation and cell surviv

7 The results identify an essential role for activity-dependent BDNF release in the rapid an

8 idism are independent of NCoR1, suggesting a role for additional signaling modulators in hypothyroidi

9 ntermediaries (Smads), we demonstrated a key role for ALK2 in the BMP9/BMP10-induced surface expressi

10 These studies definitively rule out a role for all conserved consensus PKA phosphorylation sit

11 Previously, we identified a role for alpha3beta1 in promoting the processing of lami

12 lix from deuterium uptake, consistent with a role for alphaB in dimer formation.

13 These results also demonstrate an important role for amygdala function as a mediator of this relatio

14 ith the CD3 co-receptor, suggests a possible role for an allosteric mechanism in TCR signalling.

15 nt HDM-induced DNA damage, revealing a novel role for antioxidants and NOX inhibitors in mitigating a

16 esults identify for the first time a pivotal role for Arg-dependent polyamine production during Plasm

17 In this study adipocyte-autonomous roles for ARL15 were investigated using conditional knoc

18 esis, and for pathways consistent with known roles for astrocyte processes, such as GABA and glutamat

19 chronic infection, and identify an intrinsic role for autophagy in the T. gondii parasite and its clo

20 Emerging evidence suggests novel roles for bacterially derived vitamin K forms known as m

21 These results establish a regulatory role for BCAT1 in macrophage function with therapeutic i

22 A role for BCGM in conditioning expression divergence betw

23 Here, however, we have exposed a critical role for BCL-W in B cell survival and lymphomagenesis.

24 e results also suggest a non-cell autonomous role for BDNF in the DRN in mediating antidepressant eff

25 sin genes and functional analysis supports a role for beta-defensins in regulating bull sperm functio

26 arge distribution, thus opening new possible roles for betaS in Parkinson's and other neurodegenerati

27 ntestinal inflammation, indicating a crucial role for Blimp1 in T cell homeostasis regulation.

28 This is the first demonstration of a role for BLOC-1 in ciliary assembly and highlights the c

29 ale screens, leading to the discovery of new roles for BMP signaling in linking mitochondrial homeost

30 nital infection, we demonstrate a protective role for both Chlamydia-specific immunoglobulin G (IgG)

31 nanoparticles and identified an unsuspected role for C3 in regulating the production of IFN-alpha fo

32 LR2, a lesser role for TLR4, a supplementary role for C5aR, and no apparent activity of C5L2 in infec

33 chanistic investigations demonstrated causal roles for CADM1, SPHK1, and YAP/TAZ in mediating metasta

34 The present study demonstrates a pivotal role for calpains in mediating HFD-induced adipose tissu

35 s with both oncogenic and tumour-suppressing roles for cancer progression, such as the insulin-like g

36 We focus on roles for CARMILs in signaling in addition to their func

37 Collectively, our findings demonstrate a new role for caspase-3 in the neurobiology of tau, and sugge

38 CaMKII interaction, identifying an important role for CaV1.3 L-CDF in regulating neuronal excitabilit

39 Here, we describe a role for CBR1 in metabolism of glucocorticoids.

40 Notably, multiple studies point to a unique role for CD57(+) NK cells in cancer immunosurveillance,

41 We also report a previously unappreciated role for CD8(+) T-cells in mediating rVSV-EBOV protectio

42 site for negative behaviors, and the causal role for CeA circuits underlying appetitive behaviors is

43 iviral therapies and point to a multifaceted role for chemokine receptor binding in promoting HIV-1 e

44 We uncover a dual regulatory role for chromatin during DNA replication: promoting ori

45 with CpG-rich regions plays an instrumental role for chromatin targeting and subsequent implementati

46 In this study, we report a novel role for ciliary ectosomes in building the elaborate pho

47 , we investigated this novel transcriptional role for CLOCK in human neurons by performing chromatin

48 Collectively, our results support a role for CML36 as a Ca(2+) sensor that binds to and modu

49 In sum, the decline in the ecological role for cod that began with overfishing in this ecosyst

50 l theories, because rodent models indicate a role for complement proteins in synaptic pruning and neu

51 ovides novel mouse models to further examine roles for cotranscriptional/post-transcriptional gene re

52 These data suggest a key role for CPSF100 in locating poly(A) sites and affecting

53 inactivation and Bcl2 dependence and show a role for Crebbp inactivation in the induction of Myc exp

54 ognized in ecological studies, reveals a key role for cryptic diversity in structuring communities of

55 These observations suggest a potential role for CT-1 in the regulation of metabolic circadian r

56 Our results reveal an unexpected role for CtsB in leukocyte extravasation and transmigrat

57 e first time, to our knowledge, an important role for CXCR3 and CXCL10 in the tissue distribution of

58 We present a new foundational role for CXCR3(+) monocytes/macrophages in the process o

59 ne synthesis, supporting a major presynaptic role for D2S.

60 These results expose a unique role for deltaKD-Thr(507) phosphorylation (that does not

61 ng, and identifies diverse, yet well-defined roles for different Na(+)-coordinating residues.

62 the G2-M transition as well as yet undefined roles for differentiation regulators (e.g., CLE peptides

63 hese noncoding variants, showing a causative role for DONSON disruption in MMS.

64 ransformation, and suggest oncogene-specific roles for DUSP5 in controlling ERK signaling and cell fa

65 F-2, and we also identified an unappreciated role for E2F-2 in erythroblast enucleation.

66 rs are infrequent, casting doubt on a direct role for E2Fs in driving cancer.

67 rate functionally distinct, but cooperative, roles for each kinase in preserving genome stability in

68 ral activity profiles that suggest different roles for each subtype at the start and end of tethered-

69 by ultraviolet light, suggesting a potential role for EAF2 in androgen regulation of DNA repair in pr

70 This study defines a new role for EBNA3A in the suppression of apoptosis with imp

71 These results suggest a novel role for EMCN as a potent regulator of angiogenesis and

72 The data suggested a role for Env glycoform heterogeneity in the activation o

73 he periglomerular layer, revealing a crucial role for EphA4 in facilitating efficient neuroblast migr

74 pecific inducible Cre driver revealed unique roles for epicardium-derived Shha in myocardial prolifer

75 Collectively, these results reveal a novel role for Erk5 during bone maturation and homeostasis in

76 Here we identify a critical role for ETAA1 in this process by surveying random germ

77 This study identifies a specific role for EVL and VASP in T-cell diapedesis and trafficki

78 esults are more consistent with a permissive role for experience in the development of direction sele

79 than for their retinal inputs, indicating a role for extraretinal mechanisms.

80 Collectively, these results point to a novel role for EYS in maintaining the morphological structure

81 ese studies reveal a previously unrecognized role for FOXA2 in regulation of adult uterine function a

82 -of-function experiments revealed a critical role for FOXO transcription factors in mediating these p

83 By ruling out an essential role for fractalkine signaling, our study narrows the se

84 These results imply a novel role for functional information-processing loops in opti

85 in treating HF and the potential therapeutic role for Gbetagamma-GRK2 inhibition in limiting patholog

86 ibitor PP2 rescued this effect, suggesting a role for GCs in promoting c-src-mediated proteosomal deg

87 Our study has identified a fundamental role for GDF6 and BMP signaling in governing an embryoni

88 These results demonstrate a critical role for genetic variation in ChrY in regulating suscept

89 Observations: While there is an emerging role for germline genetic testing potentially predicting

90 labelling of cells using our system reveals roles for glia in dendrite extension.

91 We exploit this bottleneck to define roles for glial Netrin and Semaphorin in pioneer- and fo

92 Compensatory roles for global-genome (XPC-1) and transcription-couple

93 r efficient pre-mRNA splicing and indicate a role for H2A.Z in coordinating the kinetics of transcrip

94 methylation activity and point to a possible role for H3K4me1 on cis-regulatory elements in specific

95 Here we examined a role for HCN channels, given their ability to alter syna

96 Thus, these results demonstrate a key role for HDAC1 in PU.1 gene transcription and, more impo

97 ically distinct and potentially nonredundant roles for high- and low-affinity Tregs in controlling au

98 Here, we show that a dual role for Hippo effectors TAZ and YAP in SC proliferation

99 xperimental and epidemiologic data suggest a role for hormone-related exposures in ovarian carcinogen

100 that liver fibrosis manifested a beneficial role for host survival and apoptosis resistance.

101 We explore potential regulators and find a role for HSF1 in the induction of a subset of heat shock

102 These data provide genetic evidence for a role for IFI16 in protection against genital herpes.

103 Murine and human lupus studies revealed a role for IFN-alpha in vascular abnormalities associated

104 , our data suggest a previously unrecognized role for IL-27 in regulating epithelial cell proliferati

105 the present study, we demonstrate divergent roles for IL-10 depending on the site of infection.

106 HPV-negative HNSCCs and suggest a potential role for impaired H3K36 methylation in their development

107 Recent studies have reported key roles for individual miRNA editing events, but a compreh

108 We also found that m(6)A has important roles for inducible degradation of Socs mRNAs in respons

109 Growing evidence supports a role for infection in the etiology of acute lymphocytic

110 These data support a role for inflammation early in the disease process, and

111 Increasing evidence suggests a role for inflammation in neuropsychiatric conditions, in

112 integrin alphavbeta3, revealing an important role for integrins in modulating risk for neuropsychiatr

113 ed deletions, we demonstrate a physiological role for intragenic enhancer-mediated transcription atte

114 munity, Liew et al. (2017) reveal a critical role for invariant natural killer T (iNKT) cells in swit

115 inge of the inner helix suggest an important role for its bulky sidechain in the allosteric mechanism

116 Our findings highlight a role for keratinocytes and their interplay with myeloid

117 Our study identifies novel roles for KIN10 and TPS1 in mediating a signal that unde

118 patient survival, consistent with a pivotal role for KLF10 in distinguishing the antiproliferative v

119 nd persistent cell cycling consistent with a role for KLF3 in dampening KLF1-driven proliferation.

120 xpression of enhancer RNAs pointed a central role for Kruppel-like factor, MEF2C, ETS, NFY, ATF, E2F2

121 Molecular simulations predict an additional role for linker O-glycans, namely that they are responsi

122 In this study, we established a role for lncRNAs in chondrocyte differentiation.

123 These findings suggest a role for long LRCs in dampening variation in gene expres

124 udies may determine whether there might be a role for losartan in specific vulnerable subgroups.

125 These data support a role for loss of HBEGF in the neuroblastoma tumor microe

126 lammatory contexts and suggest a therapeutic role for manipulating OXPHOS in Th17-driven diseases.

127 ange of timescales as they play an essential role for many cellular functions during protein-protein

128 eral human and mouse studies have implicated roles for matrix metalloproteinases (MMPs), particularly

129 Collectively, these results uncover a novel role for mDia1 in Abeta-mediated synaptotoxicity and dem

130 ed antibody to Mac1, we demonstrate a causal role for microglia in the development, but not maintenan

131 disease and define previously unappreciated roles for Micu2 in regulating angiotensin II-mediated hy

132 describe here for the first time a critical role for miR-424 in the regulation of HPV replication.

133 ken together, these data suggest a potential role for miR-7 as an RNA-based therapeutic to treat refr

134 We propose a role for miR-718 in controlling TLR4 signaling and infla

135 Remarkable new roles for mitochondria in calcium handling, apoptosis, h

136 Genetic perturbation revealed physiological roles for mitochondrial enzyme COX10-mediated oxidative

137 They also observe an unexpected role for MLL2 in MLL-rearranged leukemia cells and ident

138 These results support a role for monocytes and macrophages in the pathogenesis o

139 ent theories have argued that there is a key role for motivation in modulating empathic experiences.

140 nd remove this and other marks have revealed roles for mRNA modification in nearly every aspect of th

141 Taken together, these data unveil a role for mTORC1 and autophagy in the pathogenesis of ske

142 t mTORC1 activator and suggest unanticipated roles for mTORC1 downstream of TBK1 in control of innate

143 Our findings define a role for mTORC2 in macrophages in integrating signals fr

144 support unappreciated and dominant oncogenic roles for MYF5 and MYOD convergence on common transcript

145 Our findings reveal a previously unsuspected role for MZB cells in controlling the TFH-germinal cente

146 These data reveal an essential role for n1-src in amphibian neural development and sugg

147 pression pattern, we investigated a possible role for n1-src in neurogenesis.

148 vide in vitro physiology data supporting the role for NCX-9 in handling calcium exchange at the mitoc

149 g density for both TCRs and CARs suggested a role for negative regulators in both systems.

150 OFC circuits, possibly indicating a broader role for neuromodulators in the dynamic reconfiguration

151 temporal dementia and highlight an important role for neuron-derived progranulin in maintaining norma

152 t a potential beneficial rather than adverse role for neutrophils in pediatric severe asthma pathophy

153 uman disease, thereby emphasizing a critical role for NK cells in human antiviral defense.

154 Our findings reveal an unexpected new role for NKG2D in the regulation of B1a cell development

155 studies have suggested a positive regulatory role for NLRX1 in inducing antiviral responses.

156 We further demonstrate an important role for non-adrenergic sympathetic co-transmitters in m

157 Emerging evidence implicates a key role for non-mutational drug resistance mechanisms under

158 Altogether, our results support roles for non-Cas nuclease(s) during crRNA maturation an

159 Our data suggest a critical role for nonclassical monocytes in the pathology of TBI

160 These findings demonstrate a pathogenic role for NPC:glioma interactions and potential therapeut

161 id-derived 2-like 2 (Nrf2), supporting a key role for Nrf2 in control of mitochondrial biogenesis.

162 AIV airborne transmissibility by revealing a role for NS1 and characteristics of viral replication in

163 ar periphery and requires Nup2, suggesting a role for nuclear pore complexes.

164 re also used in C57BL/6J mice to confirm the role for nucleus accumbens (NAC) glutamate/Homer2 expres

165 of SREBP-1 in cancer and suggests a crucial role for O-GlcNAc signaling in transducing nutritional s

166 Our results suggest a physiological role for oligomerized condensin in driving gradual chrom

167 d differentiation, these data reveal a novel role for Osr2 in regulation of palatal morphogenesis thr

168 Together, these findings identify specific roles for p100 and p105 signaling in defining DLBCL mole

169 ted bystander cortical neurons, suggesting a role for paracrine factors in induction of neuronal apop

170 Studies by Sato et al. reveal a role for parathyroid hormone 2 receptor (PTH2R) in extra

171 e survival oncogene MITF, highlighting a new role for PARP1 in melanomagenesis.

172 estigations are needed to determine possible roles for PCNA and other host proteins detected.IMPORTAN

173 r for the majority of solid cancers, but the role for PDAC in predicting survival is not well delinea

174 ion of PcG member BMI-1, suggesting opposing roles for PEITC and PcG proteins in control of tumor pro

175 ta report, for the first time, a distinctive role for peripheral TNF-alpha in the modulation of the a

176 Our data demonstrate a critical role for perisomatic inhibition mediated by PV-containin

177 findings identify a previously unidentified role for peroxisomes in macrophage inflammatory response

178 n cellular functions which suggest a central role for perturbed calcium signalling in DYT2 dystonia.

179 al pertussis is characterized, and a central role for pertussis toxin (PT) is described.

180 Our results support a role for phenylalanine-derived small molecules in prefor

181 This study demonstrates a role for phosvitin, an intrinsically disordered phosphop

182 This study reveals novel roles for Pif1, Rad52, and Siz1-dependent sumoylation in

183 46-58) bring to light a functional role for plant homeodomain finger 11 (PHF11) in 5' end r

184 Previous studies suggested a role for PLC2 in MAMP-triggered immunity, as it is rapid

185 c target in cancer patients and reveal a new role for Plk4 in regulating Arp2/3-mediated actin cytosk

186 ia chains on SynCAM 1, suggesting a critical role for polyST autopolysialylation in substrate selecti

187 This study provides in vivo indication of a role for postsynaptic factors in amphetamine-induced psy

188 nd, to our knowledge, previously unsuspected role for postsynaptic kainate receptors in the induction

189 lectively, our findings uncover an essential role for PRDM15 as a chromatin factor that modulates the

190 in ciliary functions, confirming the central role for primary cilia in Hh signaling.

191 nactivation by AMPylation and point toward a role for protein AMPylation in the regulation of cellula

192 These data uncover a direct role for RANK in lung cancer and may explain why female

193 of in vitro data has demonstrated a central role for receptor ubiquitination in endocytic sorting.

194 NIFICANCE STATEMENT Our study demonstrates a role for reduced Slc6a15, a neutral amino acid transport

195 ordinate RNA binding - suggesting a possible role for regulation of RNA binding by tyrosine kinase si

196 icity they also give evidence of a promising role for resveratrol in the prophylaxis and therapy of A

197 By using an anti-reticulon-1 Ab, a role for reticulon-1 in macrophage migration toward both

198 Together, our findings establish a role for RFRP-3 in preserving reproductive immaturity, a

199 ese findings reveal a clinically-significant role for RPGR in the activation of gelsolin, without whi

200 These results reveal an important role for RUNX3/CBF during B cell transformation and EBV

201 These findings support an integral role for satellite cells in the aetiology of lean tissue

202 These findings reveal an important role for selective termination of lncRNA transcription i

203 These studies suggest a potential role for selenium supplementation as an adjuvant therapy

204 Together, our study implicates a critical role for Set1A catalytic methyltransferase activity in r

205 K4me3 in Set1A(DeltaSET) cells, suggesting a role for Set1A independent of its catalytic domain in ES

206 uch a function, supporting instead a crucial role for SHH in promoting proliferation of these RP prog

207 Our work highlights novel roles for Shot in mitosis and suggests a mechanism invol

208 sis in humans and mice, suggesting a crucial role for SHP2 in the skeleton.

209 Together, these data suggest a novel role for SIRT6 in maintaining muscle mass by controlling

210 rior work to further substantiate a critical role for skin migratory dendritic cells and in particula

211 sponses to cisplatin treatment, supporting a role for SLC16A5 in the development of cisplatin-induced

212 Consistent with a conserved role for SLC25A3 in copper transport, its heterologous e

213 ogether, our results support a novel nuclear role for SmgGDS in protecting malignant cells from nucle

214 A role for smooth muscle ARHGEF1 in asthmatic airway hyper

215 ons (SFRs) are believed to play an important role for social interactions.

216 salivary gland, we demonstrate an unexpected role for SOX2 and parasympathetic nerves in generating t

217 Emerging research establishes a role for specialized signalling filopodia, or cytonemes,

218 to sphingosine-1-phosphate, and suggested a role for sphingosine phosphorylation in endocytic membra

219 d HIV-infected human monocytes, suggesting a role for sPrP(c) in monocyte recruitment into the brain.

220 ly misfolded protein, two previously defined roles for Sse1.

221 T6Gal-I expression, further substantiating a role for ST6Gal-I in cell survival.

222 uminal Ca(2+) These findings define critical roles for Stac3 in EC coupling and human disease.

223 a null model and reveals an underappreciated role for stochasticity in language evolution.

224 a has never been reported, and no biological role for such a modification has ever been proposed.

225 ophase and telophase, potentially suggesting roles for such channels in cell division.

226 We infer an ancient role for SURF in regulating UPF1, and the intriguing pos

227 sive peripersonal space (DPPS) has a crucial role for survival, and its modulation is fundamental whe

228 wth and development, suggesting an important role for synonymous codon usage in organism physiology.

229 Despite emerging data indicating a role for T cells in profibrotic cardiac repair and heali

230 ow spore wall assembly defects, supporting a role for TAG and/or its metabolites in spore wall morpho

231 In this study, we describe a role for talin in maintaining the homeostasis and surviv

232 These results suggest an important role for tau in regulating cytoskeletal organization and

233 TLR3; TLR4), revealing a stimulus-selective role for TBK1 in mTORC1 regulation.

234 Our findings establish a tumor-promoting role for TCF7L1 in skin and elucidate the mechanisms und

235 Our findings support an important role for the adipose PPARgamma-adiponectin axis in susce

236 Similarly, a possible role for the BCR or circulating Ab in mediating CTL resp

237 or B. bronchiseptica and reveal an important role for the Bvg- phase in these interactions.

238 ng N-terminal ZF region; however, a specific role for the C-terminal set of five ZFs remains to be el

239 Although evidence suggests a role for the cerebellum in cognition, granule cells are

240 Here we show a peculiar role for the chemokine CXCL12 secreted in early PDAC and

241 Here we examined a possible role for the DNA dioxygenase, ten-eleven translocation p

242 Our study unveils a role for the endocannabinoid system in maintaining immun

243 In summary, these results reveal a new role for the helicase complex in 3' cap-independent tran

244 In this report, we propose a distinct role for the hexon protein as a "molecular mold" in enab

245 mphoid cells (ILCs), we demonstrated a major role for the HPA pathway in host resistance to endotoxin

246 AD, emerging evidence indicates a potential role for the IL-17A signaling axis in AD pathogenesis.

247 ng the release of TNF-alpha, and indicated a role for the inflammasome sensor NLRP3 and for potassium

248 Overall, we demonstrate an important role for the inflammatory response in regulating MERS-Co

249 ase may look like and suggesting a potential role for the juxtamembrane region in enzyme activity.

250 In conclusion, our results reveal a role for the KCNQ1 potassium channel in the regulation o

251 ere is no experimental evidence ruling out a role for the lipid bilayer in their ion channel effects.

252 ty associated with CLP and indicate a direct role for the major CLP gene Irf6 in salivary gland devel

253 5%-71% of the peaks, suggesting a widespread role for the mechanism.

254 We have explored a role for the metal transporter ZIP14 during pharmacologi

255 lts of this genetic study support a possible role for the mineralocorticoid receptor in the pathogene

256 Together these data suggest a novel role for the myospryn complex in the assembly of ryanodi

257 Here, we describe a unique role for the orphan catalytic subunit CcoN4 in colony bi

258 downstream of Gq and identified an important role for the PLCbeta-PKCalpha pathway, possibly regulati

259 en formation, hence demonstrating a distinct role for the R-Ras-Akt axis.

260 Here, we report a pivotal role for the R-spondin/leucine-rich repeat-containing G

261 infection in bees and revealed an important role for the regulation of the bee antiviral immune resp

262 n oligodendrocytes, indicating a paradoxical role for the retrograde dynein/dynactin complex in anter

263 These data together establish an important role for the Tet2-Foxo3a axis in epigenetically regulati

264 hemotherapeutic strategy and its significant role for the treatment of drug-resistant TNBC.

265 s ubiquitin ligase and revealed an important role for the ubiquitin pathway in effector-host interact

266 Gosmann et al. (2017) reveal a putative role for the vaginal microbiome in modulating heterosexu

267 findings indicate a memory-based "autopilot role" for the default mode network, which may have impor

268 The results identify crucial roles for the active site amino acid trio in determining

269 upports developmental and pathophysiological roles for the MET receptor tyrosine kinase, a multifunct

270 xiliary (TARP) subunits, revealing essential roles for the receptor transmembrane and cytoplasmic dom

271 Functional evidence supports broad roles for the TRN in arousal, attention, and sensory sel

272 al for proper CNS function, but the relative roles for the two main sources of ATP production, glycol

273 To confirm a cardiovascular role for these candidate genes in vivo, we used morpholi

274 synthase, suggesting a potential protective role for these IFN-gamma-producing cells.

275 This study demonstrates disparate roles for these lipids in the stability and mobility of

276 PTH secretion in vivo and in vitro, implying roles for these specific miRNAs.

277 These findings shed light on a novel role for this conserved domain in providing the necessar

278 ued by deleting upd3, highlighting a crucial role for this cytokine.

279 n glycolysis/gluconeogenesis and uncovered a role for this factor in regulating anaerobic glycolysis.

280 Recent studies identified a crucial role for this pathway in activity-dependent long-term de

281 orms of CLP, we find no evidence of a direct role for this transcription factor in development of thi

282 y with iron, indicating a new biogeochemical role for this ubiquitous microorganism.

283 re neurological in nature revealing critical roles for this class of proteins in the brain.

284 play yolk sac vascular defects, suggesting a role for thrombin signaling in vessel development.

285 xperiments in knockout mice revealed a major role for TLR2, a lesser role for TLR4, a supplementary r

286 ice revealed a major role for TLR2, a lesser role for TLR4, a supplementary role for C5aR, and no app

287 ially attenuated this expression, suggesting roles for TLR7/8 in induction of fibrocytes in HCV infec

288 randial serum triglycerides, suggestive of a role for TM6SF2 in the small intestine.

289 r, these results reveal a previously unknown role for transcription factor IIH in ATR kinase activati

290 ts potency to resolve AAI supports a crucial role for transcriptional regulation by the GR in this ce

291 These findings indicate a major role for TRPV4 in Ca(2+) homeostasis and barrier functio

292 In revealing an important role for Ube3A/E6AP in ASD-related developmental alterat

293 were observed in the cytoplasm, suggesting a role for UL21 in preventing their exit from the nucleus.

294 ly on phosphorylation for activation and new roles for unphosphorylated response regulators have been

295 ginosa urinary tract infection, suggesting a role for urinary antimicrobial peptides in susceptibilit

296 s challenge virus, highlighting an important role for vaccine-induced CD4(+) cells in cross-protectiv

297 d in the mutant forebrain, consistent with a role for Vax1 in mediating transduction of this pathway.

298 hepatocytes, these data indicate a potential role for Vpr in HIV-associated fatty liver disease.

299 as9 somatic mutagenesis to test a patterning role for WntA, a signaling ligand gene previously identi

300 These results define direct structural roles for yeast CAF-1 subunits and uncover a previously