ライフサイエンスコーパス: role for

1 nesis in mice treated with DEN, and identifies an important role for ACC enzymes in redox regulation and cell survival.

2 the signaling intermediaries (Smads), we demonstrated a key role for ALK2 in the BMP9/BMP10-induced surface expression of

3 interactions with the CD3 co-receptor, suggests a possible role for an allosteric mechanism in TCR signalling.

4 We uncover a dual regulatory role for chromatin during DNA replication: promoting origin d

5 Collectively, our results support a role for CML36 as a Ca(2+) sensor that binds to and modulates

6 lex, rarely recognized in ecological studies, reveals a key role for cryptic diversity in structuring communities of mutu

7 These observations suggest a potential role for CT-1 in the regulation of metabolic circadian rhythm

8 Our results reveal an unexpected role for CtsB in leukocyte extravasation and transmigration,

9 due to one of these noncoding variants, showing a causative role for DONSON disruption in MMS.

10 scription factors are infrequent, casting doubt on a direct role for E2Fs in driving cancer.

11 n be modulated by ultraviolet light, suggesting a potential role for EAF2 in androgen regulation of DNA repair in prostat

12 These results suggest a novel role for EMCN as a potent regulator of angiogenesis and point

13 is required for efficient pre-mRNA splicing and indicate a role for H2A.Z in coordinating the kinetics of transcription

14 Thus, these results demonstrate a key role for HDAC1 in PU.1 gene transcription and, more important

15 gs demonstrated that liver fibrosis manifested a beneficial role for host survival and apoptosis resistance.

16 We explore potential regulators and find a role for HSF1 in the induction of a subset of heat shock-indu

17 Our findings highlight a role for keratinocytes and their interplay with myeloid cells

18 In this study, we established a role for lncRNAs in chondrocyte differentiation.

19 aporin-conjugated antibody to Mac1, we demonstrate a causal role for microglia in the development, but not maintenance, o

20 We propose a role for miR-718 in controlling TLR4 signaling and inflammato

21 Our findings reveal a previously unsuspected role for MZB cells in controlling the TFH-germinal center res

22 These data reveal an essential role for n1-src in amphibian neural development and suggest t

23 erved at high Ag density for both TCRs and CARs suggested a role for negative regulators in both systems.

24 Our findings reveal an unexpected new role for NKG2D in the regulation of B1a cell development.

25 n approaches were also used in C57BL/6J mice to confirm the role for nucleus accumbens (NAC) glutamate/Homer2 expression

26 , migration, and differentiation, these data reveal a novel role for Osr2 in regulation of palatal morphogenesis through

27 Studies by Sato et al. reveal a role for parathyroid hormone 2 receptor (PTH2R) in extracellu

28 of longer polySia chains on SynCAM 1, suggesting a critical role for polyST autopolysialylation in substrate selection an

29 This study provides in vivo indication of a role for postsynaptic factors in amphetamine-induced psychosi

30 were involved in ciliary functions, confirming the central role for primary cilia in Hh signaling.

31 mode of Hsp70 inactivation by AMPylation and point toward a role for protein AMPylation in the regulation of cellular pro

32 These data uncover a direct role for RANK in lung cancer and may explain why female sex h

33 Together, our findings establish a role for RFRP-3 in preserving reproductive immaturity, and ch

34 These studies suggest a potential role for selenium supplementation as an adjuvant therapy in C

35 Together, our study implicates a critical role for Set1A catalytic methyltransferase activity in regula

36 red cellular responses to cisplatin treatment, supporting a role for SLC16A5 in the development of cisplatin-induced otot

37 man and murine salivary gland, we demonstrate an unexpected role for SOX2 and parasympathetic nerves in generating the ac

38 nts with high ST6Gal-I expression, further substantiating a role for ST6Gal-I in cell survival.

39 change against a null model and reveals an underappreciated role for stochasticity in language evolution.

40 th organism growth and development, suggesting an important role for synonymous codon usage in organism physiology.

41 Despite emerging data indicating a role for T cells in profibrotic cardiac repair and healing af

42 Here we show a peculiar role for the chemokine CXCL12 secreted in early PDAC and for

43 Our study unveils a role for the endocannabinoid system in maintaining immune hom

44 AM receptor kinase may look like and suggesting a potential role for the juxtamembrane region in enzyme activity.

45 We have explored a role for the metal transporter ZIP14 during pharmacologically

46 the signaling downstream of Gq and identified an important role for the PLCbeta-PKCalpha pathway, possibly regulating ac

47 g upd3 and rescued by deleting upd3, highlighting a crucial role for this cytokine.

48 Recent studies identified a crucial role for this pathway in activity-dependent long-term depress

49 tly lower postprandial serum triglycerides, suggestive of a role for TM6SF2 in the small intestine.

50 oincided with its potency to resolve AAI supports a crucial role for transcriptional regulation by the GR in this cell ty