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2 we present clear evidence of the LxL cycle's role in modulating a rapid component of NPQ that is nece
3 at are known to play critical, but distinct, roles in modulating a variety of physiologically relevan
4 on of the xanthene benzoate plays a critical role in modulating Abeta aggregation and cytotoxicity.
5 l metabolites, and other steroids may play a role in modulating Abeta production and thus risk for AD
7 gnment was previously found to have a causal role in modulating activation of inflammatory versus ant
13 re rich in androgen receptors and play a key role in modulating aggressive behavior in animal models.
14 icrobial communities (microbiota) may have a role in modulating allergic and immune disorders of the
15 eceptor subtype 1 but not 2 plays a critical role in modulating AMPAR clustering, suggesting that tar
16 r domains of AMPAR and STZ play an important role in modulating AMPAR function through contact surfac
18 ally known to regulate histone function, its role in modulating antiviral restriction factor activity
23 indicate that norepinephrine may play a key role in modulating arousal states and NREM EEG delta pow
25 ions are scattered randomly, consistent with roles in modulating assembly of higher-order structures
27 hat dACC excitatory neurons play a principal role in modulating attention to task-relevant stimuli.
28 smission has been shown to play an important role in modulating attentional processing of visual stim
29 adrenaline or noradrenaline, plays important roles in modulating behavior and synaptic functions.
30 onstrate that sleep plays a more fundamental role in modulating behavioral plasticity than previously
31 effects suggest that the G72 gene may play a role in modulating behaviors relevant to psychiatric dis
32 targets and events may also play a critical role in modulating biological responses to ionizing radi
33 tein in a genetic model reveals an important role in modulating BMP signaling during the asymmetric d
35 tions such as phosphorylation play a crucial role in modulating both the tertiary and quaternary stru
36 ection of breast cancer, and their suggested role in modulating breast cancer cell behaviour, very li
39 protein-C phosphorylation plays an important role in modulating cardiac muscle function and accelerat
41 esults indicate that DnaA plays an important role in modulating cell physiology, separate from its ro
42 kine receptor type 4 (CXCR4) plays a crucial role in modulating cell trafficking in hematopoietic ste
44 ge of a myriad of genes, which play critical roles in modulating cell cycle arrest, DNA repair, and c
45 ones, brassinosteroids (BRs), play essential roles in modulating cell elongation, vascular differenti
46 Extracellular microenvironments have crucial roles in modulating cell interactions during development
50 tification that Parkin has a multifunctional role in modulating cellular fatty acid uptake and mitoch
52 ee radical production, may play an important role in modulating cellular signaling under conditions o
54 expression changes induced by smoking, their role in modulating changes associated with lung cancer i
55 conformational dynamics of PAGE4 may play a role in modulating changes between PCa cell phenotypes.
57 ssential Argonaute CSR-1 to play key nuclear roles in modulating chromatin, chromosome segregation an
58 atch repair (MMR) pathways play an important role in modulating cis-Diamminedichloroplatinum (II) (ci
60 er, we reveal that attention plays a crucial role in modulating competition; without attention, rival
62 expressed in the heart, yet their functional roles in modulating contractile function remain incomple
63 n the cerebral cortex, which play a critical role in modulating cortical output to the basal ganglia,
65 e for a yin-yang of IFN function through its role in modulating crosstalk between multiple cytokines
66 Our study reveals that DAB2IP has a critical role in modulating CSC properties via CD117-mediated ZEB
67 ows that viral genetic factors play a larger role in modulating disease severity than anticipated.
68 tea have been suggested to play an important role in modulating disease-risk in humans by suppressing
69 icoid-KLF11-MAO A pathway may play a crucial role in modulating distinct pathophysiological steps in
71 ries, we identified genes that play critical roles in modulating diverse functions of dendritic cells
72 mmation by Tet proteins independent of their role in modulating DNA methylation remains largely unkno
73 nt effects are implicated as playing a major role in modulating electrostatic interactions via throug
75 -containing microglia may still play a local role in modulating encephalitogenic CD4(+) T cell respon
77 r protein sorting 34 (Vps34) plays a central role in modulating endocytic pathways, maintaining podoc
79 ced aversion and suggest a mechanism for its role in modulating escalation of voluntary ethanol intak
82 glutamate (Glu) receptors (mGluRs) play key roles in modulating excitatory neurotransmission in the
84 mal B cell development and play an important role in modulating expression of the V(D)J recombinase.
85 onstrated that miRNA-449a plays an important role in modulating expression of YKL40 through targeting
86 s been shown that BK channels play a pivotal role in modulating feedback from A17 amacrine cells to r
87 e tested the hypothesis that it also plays a role in modulating flows and matrix hydration potential.
92 other epigenetic signals, plays an important role in modulating gene expression and can therefore est
96 and euchromatin are likely to have important roles in modulating gene expression and variability with
97 egulators, microRNAs (miRNAs) play important roles in modulating gene expression; therefore, we sough
99 adjacent to operons encoding GRs play major roles in modulating GR function in spores of Bacillus sp
100 refore, FXR and SHP appear to play a limited role in modulating HBV biosynthesis, suggesting that alt
102 Macrophage-derived AnxA1 plays a functional role in modulating hepatic inflammation and fibrogenesis
103 egative regulation loop that plays important roles in modulating hepatic circadian rhythmicity and ag
105 ptidoglycan deacetylation plays an important role in modulating host inflammatory responses to H. pyl
106 The intestinal microbiota plays an important role in modulating host-pathogen interactions, but littl
107 lcium chelating salts may play a more subtle role in modulating hydration during manufacture of casei
108 this signalling complex to play an important role in modulating hypothalamic neuronal excitability, w
109 -mediated Ca(2+) signalling plays a critical role in modulating hypothalamic neurosecretory function.
110 establish that cholesterol plays a critical role in modulating I(K,ACh) in atrial cardiomyocytes via
113 ar features, we conclude that GIMAP6 plays a role in modulating immune function and that it does this
114 ignaling has been shown to play a variety of roles in modulating immune responses to HSV and other pa
116 d that environmental conditions play crucial roles in modulating immunity and disease in plants and a
117 highlight that dlPFC and ipTC play a causal role in modulating implicit attitudes about violence and
121 from thalamic interneurons plays a critical role in modulating information transfer between thalamus
122 he thalamic reticular nucleus has a critical role in modulating information transfer from the thalamu
124 glucose, GLP-1, or KCl stimulation through a role in modulating insulin secretory vesicle localizatio
126 natriuretic peptides that play an important role in modulating intravascular volume and vascular ton
128 that ATP binding to synapsin IIa plays a key role in modulating its function and in defining its cont
130 beta-Catenin phosphorylation plays important roles in modulating its functions, but the effects of di
131 re we show that cholesterol plays a critical role in modulating K(ACh) currents (I(K,ACh)) in atrial
134 clock, and its C terminus plays an important role in modulating light sensitivity and activity of the
136 data demonstrate that trNK cells play a key role in modulating local responses to ischemic tissue in
138 CK2, which appears to play a key regulatory role in modulating M oligomerization and association wit
139 mation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF
141 ng of placental vitamin D metabolism and its role in modulating maternal circulating vitamin D metabo
144 ould be that the modifications play opposite roles in modulating misreading by the two classes of tRN
146 ved caspase-3, and LC-3 II/I, indicating its role in modulating mitochondrial fragmentation, oxidativ
147 function in skeletal muscle in rodents, its role in modulating mitochondrial function in the liver i
149 ta support a model in which ATM plays direct roles in modulating mitochondrial homeostasis and sugges
152 summary, TSP-1 appears to play an accessory role in modulating Mp activity in BlaJ mice in a gender,
153 profiles, and may play important regulatory roles in modulating mRNA degradation or translational ef
154 suggests that TCR pathways may play a wider role in modulating mutation frequencies in different par
155 dy demonstrates that acetylation plays a key role in modulating myocardin function in controlling car
156 ved neurotrophic factor (BDNF) has a crucial role in modulating neural and behavioral plasticity to d
158 functions in the CNS, including a potential role in modulating neuronal growth and synapse formation
160 ind H2S tightly and was postulated to play a role in modulating neuronal sensitivity to H2S in condit
162 intrinsic properties, noise plays different roles in modulating neuronal input-output curves, which
163 coagonist of the NMDAR, plays a significant role in modulating NMDAR-mediated synaptic transmission
167 m bone marrow stromal cells (BMSCs), takes a role in modulating osteoblast and osteoclast formation.
170 e-receptor-positive breast tumors and play a role in modulating pathway choice for the repair of doub
171 in the Sphagnum bryosphere play an important role in modulating peatland C cycle responses to experim
172 d the first extracellular loop have critical roles in modulating peptide ligand binding and receptor
173 on or ESLD (<30 mg/dl) and appears to have a role in modulating PGE2-mediated immune dysfunction.
176 Thus, in addition to its well-established role in modulating proliferation during periods of tissu
177 onalize the dynamics of S-thiolation and its role in modulating protein nanomechanics, offering molec
178 dependent methyltransferases plays essential roles in modulating protein function in both normal and
180 -translational modifications play a critical role in modulating RB activity, but additional levels of
185 iminished rPPC grey matter volume may have a role in modulating risk preferences in older adults.
187 at both adrenergic sensors play an important role in modulating several aspects of S. Typhimurium pat
188 results suggest that L(pro) plays a pivotal role in modulating several pathways of the immune respon
189 r with grazing pressure, plays a significant role in modulating shrub encroachment and ensuing land d
190 Regulated actin dynamics play a central role in modulating signaling events at the immunological
193 poxygenase (5LO), herein we investigated its role in modulating stress-dependent development of the A
195 ycans within the A2 domain play an important role in modulating susceptibility to ADAMTS13 proteolysi
197 been clearly demonstrated to serve critical roles in modulating synaptic signaling and plasticity th
201 s in patients suggest that SP110 plays a key role in modulating TB susceptibility in concert with NFk
204 that magnesium and calcium ions play a major role in modulating the ability of these enzymes to act a
206 ults demonstrate that IL-10 plays a critical role in modulating the adaptive immune response to RSV b
207 ) (N17) has been suggested to play a crucial role in modulating the aggregation propensity and toxici
208 test the hypothesis that the mPFC has a dual role in modulating the amygdala and PAG in juveniles, we
209 ts demonstrate that ZNF24 plays an essential role in modulating the angiogenic potential of microvasc
210 eferred to as the "microbiome," play a vital role in modulating the balance between clearance of path
212 onstrate that PEPC in leaves plays a crucial role in modulating the balance of carbon and nitrogen me
213 o PD models, we show that Nox1 has a crucial role in modulating the behavior of alpha-synuclein expre
214 g involved in ERAD of SUR1 and Kir6.2, has a role in modulating the biogenesis efficiency and surface
215 osylation of N-glycoproteins plays a crucial role in modulating the biological functions of glycoprot
216 ese results suggest that CstF-64 plays a key role in modulating the cell cycle in ESCs while simultan
217 cific Ocean does play an early and important role in modulating the changes in atmospheric CO2 concen
218 our data suggest that the wrist domain has a role in modulating the channel's response to external st
219 sulfates along native GAG chains may play a role in modulating the characteristics of the HSV-GAG in
220 hallmark of an adaptive immune response, its role in modulating the chronic inflammation that accompa
222 l function of inclusions and their potential role in modulating the consequences of aggregation.
223 Subglacial topography plays an important role in modulating the distribution and flow of basal wa
225 e serotonin 1A receptor (5-HT1A) has a major role in modulating the effects of serotonin on mood and
227 that ICP27 plays a heretofore-unappreciated role in modulating the efficiency of progeny virion rele
228 biota and soil organic matter may play a key role in modulating the environmental effect of nanomater
229 s on the eukaryotic cell have played a major role in modulating the evolution of the mitochondrial ge
230 n a reaction cavity would play a significant role in modulating the excited state properties of molec
231 ognized that molecular chaperones play a key role in modulating the formation of amyloid fibrils, a p
232 l geniculate nucleus (dLGN) and play a major role in modulating the gain of thalamic signal transmiss
233 ction with DNA, CATH-2 can play an important role in modulating the immune response at sites of infec
234 t Tyr(1092) and Tyr(1143) plays an important role in modulating the inhibitory effect of WNK4 on ROMK
235 sular polysaccharides that play an important role in modulating the initial interactions once the bac
236 consistent with the INS playing an important role in modulating the intrinsic functional connectivity
237 nscriptional regulator Id-1 plays a critical role in modulating the invasiveness of glioblastoma cell
238 a profibrotic growth factor in CKD, but its role in modulating the kidney's response to AKI is not w
241 n of phyB abundance does not play a dominant role in modulating the magnitude of the PIF-promoted, sh
242 cs at the ice surface may play a significant role in modulating the mechanism and rate of heterogeneo
243 previously demonstrated to play an important role in modulating the migration of monocytes, neutrophi
244 ed that HCV core protein plays a significant role in modulating the mTOR/S6K1 signaling pathway.
246 and splenic vascular niche play an essential role in modulating the physiology of adult hematopoietic
247 olate, Y100 plays an important electrostatic role in modulating the pKa of the N5 of DHF to enable th
248 e the opposing, POP-1 activity, suggesting a role in modulating the potency of the cellular polarizin
249 ally sweet wine and it can play an important role in modulating the production and the release of vol
250 th hypoxia, and tissue pO(2) plays a central role in modulating the progression of chronic kidney dis
253 erfacial lipids, and explored their possible role in modulating the rate of receptor association and
254 at tRNA selection plays an important general role in modulating the rates and rhythms of protein synt
255 rth Atlantic Ocean dynamics played an active role in modulating the response of the atmosphere to sol
256 Cholesterol (CHOL) molecules play a key role in modulating the rigidity of cell membranes and co
258 ore, iron impurities are shown to play a key role in modulating the selectivity of Rh/SiO2 catalysts
259 e that the alphaCPs play a direct and global role in modulating the splicing activity and inclusion o
260 opment and plays an evolutionarily conserved role in modulating the strength of synaptic transmission
261 regions, indicating that they play an active role in modulating the structural features of this CBP f
262 ession of restriction factors may play a key role in modulating the susceptibility of different popul
264 and cshA and plays an important trans-acting role in modulating the transcription and ensuing express
265 ood and other bodily fluids, play a critical role in modulating the tumor microenvironment and affect
266 Downregulation of SERCA2a plays a critical role in modulating the vascular and right ventricular pa
267 suggest that the placenta may play an active role in modulating the vitamin D metabolite profile in m
270 ng activities of gp41CD as well as potential roles in modulating the actin cytoskeleton and overcomin
271 of mammalian sodium channels play important roles in modulating the expression and gating of mammali
272 ly of secreted metalloproteases play crucial roles in modulating the extracellular matrix (ECM) in de
273 with cysteinyl S(gamma) atoms play important roles in modulating the functional and structural proper
274 RNAs carried by herpesviruses play important roles in modulating the host cell, thereby facilitating
275 N-H...S(gamma) hydrogen bonds play important roles in modulating the mechanical and kinetic propertie
276 iods should be considered as having distinct roles in modulating the metabolism of omega-6 and omega-
277 ns that function as Lewis acids play pivotal roles in modulating the reactivity of oxygen-containing
279 transcriptional regulation, play significant roles in modulating their contribution to cytokinin sign
280 ism, epigenetic mechanisms have an essential role in modulating these properties by regulating gene e
281 ted costs and that feedback plays a critical role in modulating this ability to effectively take adva
282 ions during infancy might play an additional role in modulating this causal pathway, as well as contr
284 released from platelets plays a mechanistic role in modulating thrombosis in the presence of VWF.
286 sphorylation of NF-kappaB plays an important role in modulating transcriptional activity of NF-kappaB
287 ifications are believed to have an important role in modulating transcriptional regulation of UVB-ind
288 which have been suggested to play a crucial role in modulating troponin function during beta-adrener
290 R signaling has been found to have important roles in modulating tumorigenesis and metastasis in seve
293 attractive therapeutic targets, given their roles in modulating various cancer-related signaling pat
294 tracellular matrix proteins play an integral role in modulating vascular homeostasis in health and di
295 Nitric oxide (NO) signaling plays a major role in modulating vascular tone and remodeling in the p
296 ation, the microvasculature plays a critical role in modulating vascular tone by endothelial release
297 rylated forms of beta-catenin play important roles in modulating vascular pathophysiology through dif
299 is also expressed in the brain, although its role in modulating whole-body energy balance remains unk
300 We hypothesize that Wls plays a critical role in modulating Wnt signaling during lung development
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