1 We capture the
role of the linker in a heuristic scaling model, and we
2 se findings confirm the important regulatory
roles of AlucJHEH in A. lucorum and indicate this gene a
3 These results reveal
roles of gap junctions in a complex behavior at cellular
4 ollectively, these results reveal a critical
role of miR-122 in acetaminophen detoxification and impl
5 ctor target; however, the pathophysiological
role of mitochondria in ADPKD remains uncharacterized.
6 In this study, we investigated the
role of RARRES2 in adrenocortical carcinoma (ACC), a rar
7 However, the
role of calpain in airway smooth muscle remodelling rema
8 However, the
role of this pathway in allo-HCT is previously unknown.
9 e been well-characterised, but the potential
role of these alkaloids in animal pathogenesis has not b
10 rmance parameters for coated MNs include the
role of excipients in assisting dissolution from the MNs
11 ; describes existing evidence supporting the
role of LOX-1 in atherogenesis and its major complicatio
12 We examined the
role of vascular CXCR4 in atherosclerosis and plaque com
13 Until recently, the dual
roles of mitochondria in ATP production (bioenergetics)
14 Previous reports pointed to the probable
role of COPT2 in Au transport based on the transcript ac
15 ysialylation flank the PBR, we evaluated the
role of PBR residues in autopolysialylation and found th
16 ase virus (IBDV) was used to investigate the
role of autophagy in avibirnavirus replication.
17 The
role of Hap10 in BD pathogenesis is unknown.
18 The
role of alternative splicing in beta cells remains uncle
19 lation, serving as a paradigm to explore the
role of linker histones in bio-signaling processes.
20 For each, we discuss the
role of microbiota in biogeochemical cycling and outline
21 greatly facilitate our understanding of the
role of BMP in biological systems.
22 , and vascular levels, but the cell-specific
role of Nox2 in BP regulation is unknown.
23 f these disorders helps us to understand the
role of chromatin regulators in brain development, plast
24 ich may contribute to the pathophysiological
role of neuroligins in brain disorders.
25 We addressed the
role of ROS in C57BL/6 mice following intradermal infect
26 erved in CAEBV and that implies an important
role of monocytes in CAEBV.
27 There has been controversy regarding the
role of AMPK in cancer, some of which may be due to func
28 Although many studies have examined the
role of chronic inflammation in cancer development, few
29 within proteins as a signal for the driving
role of mutations in cancer.
30 ing an additional transcriptional activation
role of MYC in cancer metabolism.
31 provide functional evidence for an essential
role of oxidative phosphorylation in cancer.
32 solve the paradox, highlighting a regulatory
role of telomeres in cancer.
33 We sought to determine the
role of gamma2-AMPK in cardiac stress response using bio
34 ccompanying paper focuses on the integrative
role of K(+) channels in cardiac electrophysiology, i.e.
35 Here, we investigated the potential
role of NDPK-C in cardiac cAMP formation and contractili
36 This manuscript reviews the
role of the ECM in cardiac repair and remodeling and dis
37 d to enhance our understanding regarding the
role of the latter in cardiac physiology and relevant di
38 nheimer" enzymes) have been used to test the
role of protein dynamics in catalysis.
39 Here, we reevaluated the
role of RelB in cDC and myeloid development using a seri
40 CD11c(+) cells, and highlights the important
role of SWAP-70 in Cer dynamics in dendritic cells.
41 and radiotherapy, little is known about the
role of histone expression in chemoresistance.
42 ed epithelial cells, signifying an important
role of CAF exosomes in chemotherapeutic drug resistance
43 The
role of germline mutations in children and adults with h
44 tural protein) were generated to explore the
role of this protein in chromatin structure and cardiac
45 tion mediators and shedding new light on the
role of fibroblasts in chronic inflammation.
46 inase 1/3, this study aimed to establish the
role of RIP3 in chronic cardiac allograft rejection.
47 3 ratio is an important consideration in the
role of FAs in cognitive function, and the optimal balan
48 These observations elucidate the
role of roughness in colloid attachment under both favor
49 hich will foster future investigation of the
role of mesentery fat in colorectal diseases.
50 nts, timing, and kinetics of the multivalent
role of ubiquitin signals in control of amplitude and se
51 The potential protective
role of B cells in controlling cCMV-related disease and
52 The central
role of protein kinases in controlling disease processes
53 The
role of species interactions in controlling the interpla
54 this species, indicating a highly conserved
role of this protein in controlling organ size.
55 To analyze the potential
role of Tregs in controlling the TCR repertoire breadth
56 This study was conducted to identify the
role of Scx in cortical bone development and fracture he
57 To understand the
role of oncogenic KRAS in CRC, we engineered a mouse mod
58 This corroborates the mediating
role of attention in crowding out.
59 We investigated the
role of skin microbiota in cutaneous leishmaniasis and f
60 induced myocarditis, we aimed to unravel the
role of NOD2 in CVB3-induced myocarditis.
61 Increasing evidence suggests a crucial
role of inflammation in cytokine-mediated beta-cell dysf
62 To investigate the
role of clathrin in DCV biogenesis, we stably transduced
63 To test the
role of Gank in degradation of CUGBP1, we generated mice
64 ive-like behaviors, pointing to an important
role of this phosphatase in depression.
65 abnormalities, and we sought to evaluate the
role of CMR in determining sudden cardiac arrest pathoge
66 ecent "magic ratio rules", which capture the
role of connectivity in determining the electrical condu
67 This study aims to identify the
role of IRF6 in development of exocrine glands, specific
68 Accumulating evidence suggests the critical
role of mGluR2/3 in different aspects of nicotine addict
69 hanistic and functional understanding of the
role of PARPs in different biological processes has grow
70 The data demonstrate fundamentally new
roles of TMEM16A in differentiated epithelial cells: TME
71 A growing understanding of the
role of DAMPs in directing the immune response to transp
72 To investigate the
role of BH4 deficiency in disease phenotypes, 12-month-o
73 ing of habitats makes them ideal to test the
role of environmental pressure in driving ecological and
74 ng differentiation, confirming the causative
role of Fus3 dynamics in driving cell fate decisions.
75 These results show evidence for the
role of prey heterogeneity in driving functional complem
76 itivity of cancer cells, consistent with the
role of hPXR in drug resistance.
77 le reviews the literature and summarizes the
role of inflammation in dry eye disease.
78 The
role of adaptive immunity in early cancer development is
79 ion and provides insight into the protective
role of C1q in early atherosclerosis.
80 tic/epigenetic investigations to explore the
role of miRNA in early stage BC in young women, includin
81 New technologies that help to unravel the
role of ambient aerosols in earth climate and to assess
82 here has been some progress in revealing the
role of epigenetics in ecological processes, studies wit
83 less bone formation, indicating a prominent
role of DA in effective bone regeneration.
84 ntrast, our results indicate a much stronger
role of temperature in embryonic development time than c
85 Understanding the
role of neurons in encoding and transmitting information
86 DF on clock gene transcription and the known
role of PDF in enhancing PER/TIM stability occur via ind
87 In order to systematically detect the
role of phenotypic variability in enteropathogenic E. co
88 In this short review, the
roles of miRNA in epidermal development, psoriasis, cuta
89 ful in the further elucidation of the causal
role of reflux in erosive tooth wear.
90 , which underscore a potentially significant
role of 5RK in exocytosis, we next amperometrically anal
91 in the cell identify a potential regulatory
role of ACPS in fatty acid biosynthesis.
92 However, the
role of Scx in fracture healing has not yet been explore
93 n of tissue-specific gene expression and the
role of gene duplication in functional novelty, but its
94 r outcomes 90 days after ICH, confirming the
role of TGF-beta1 in functional recovery from ICH.
95 sion and metastasis of some cancers, but the
role of FPR2 in gastric cancer (GC) has not yet been elu
96 To investigate the causal
role of hypoadiponectinemia in GDM, adiponectin gene kno
97 vations contribute to an appreciation of the
roles of splice isoforms in genetic disorders and sugges
98 To better understand the
roles of microRNAs in glial function, we used a conditio
99 The
role of calcium regulators in governing these processes
100 Collectively, our study demonstrates a novel
role of FANCD2 in governing cellular ATP production, and
101 These results establish dominant
roles of AMPARs in governing bidirectional synaptic and
102 The
role of mutations in GP and NP is not clear.
103 were identified almost a decade ago, yet the
role of repulsive interactions in guiding structure form
104 in further elucidation of the physiological
role of FPR2 in health and disease.
105 To describe the expanding
role of telemedicine in healthcare, the key criteria req
106 To determine the
role of ILK in hepatic insulin action in vivo, male C57B
107 However, the
role of TGR5 in hepatic metabolism has not been explored
108 also enhanced by LY6E, suggesting additional
roles of LY6E in HIV-1 replication.
109 otential to improve our understanding of the
role of global methylation in human diseases, especially
110 The
role of neuronal oscillations in human somatosensory per
111 ed for the first time, to our knowledge, the
role of PIKfyve in human and mouse neutrophils.
112 However, the
role of this cascade in human HCC remains unclear.
113 To investigate the
role of YAP1 in human eye development, we performed in s
114 ion and facilitate efforts to understand the
roles of microglia in human brain diseases.
115 To evaluate the potential
role of these residues in hydrophobic gating, Leu267 and
116 The physiological
role of these proteins in IFN-gamma signaling has not be
117 We discuss the potential
role of these biofilms in ikaite column formation.
118 groundwork for future studies to explore the
role of DNA replication in immune cell generation and fu
119 Therefore, the biological
role of CCRL2 in immunity is still unclear.
120 ides a specific mechanism accounting for the
role of IFN-alpha in immunosuppression and predicts that
121 ects of this material have been studied, the
role of defects in improving the energy storage density
122 The available evidence on the
role of arsenic metabolism in individual susceptibility
123 ts also impose restrictions on the potential
role of atmospheric CO2 in inferred warmer conditions an
124 olutionary model of inteins and a functional
role of HEN domains in inteins.
125 les-based approaches, and highlights the key
role of these calculations in interpreting increasingly
126 d by ubiquitylation and acetylation, but the
role of this residue in intrinsic KRAS function has not
127 To date there is no clear information on the
role of VEGF-A in IPF.
128 We investigated the
role of Act1 in keratinocyte responses to IL-17 using a
129 Replication studies and understanding the
roles of these genes in keratoconus are warranted.
130 We then tested the
role of JAK2/STAT3 in ketamine-induced plasticity in the
131 Whereas another review will focus on the
role of Runx factors in leukemias, this review will prov
132 Given the critical
role of BCRP in limiting fetal exposure to drugs and xen
133 c oral epithelium ( Irf6 cKO), bypassing the
role of the gene in lip and palate morphogenesis and thu
134 anel of lipid-associated genes, indicating a
role of SLC7A11 in lipid metabolism.
135 In conclusion, we present an oncogenic
role of FAM83H in liver cancer, which is closely associa
136 ken together, our study has revealed a novel
role of GSK3 in liver regeneration after APAP overdose a
137 motes the release of AA, we investigated the
role of PLA2 in local and systemic disease during S. pne
138 To study the
role of neutrophils in LPS-induced endotoxemia, we devel
139 To further investigate the
role of inflammation in lung carcinogenesis, we evaluate
140 bset of T cells with cytotoxic function, the
role of which in lung immunity is unclear.
141 s review, we present current concepts on the
role of clonal evolution in lymphoid and myeloid leukemi
142 he late-blooming phase, suggesting an active
role of this group in lysing P. donghaiense cells.
143 Here, we investigated the
role of HCA2 in macrophage-mediated inflammation and the
144 These results confirm the critical
role of parrotfish in maintaining coral-dominated reef h
145 This review will focus on the
role of cell death in maintenance of T-cell homeostasis
146 Although the pathogenic
role of Mycoplasma genitalium in male urethritis is clea
147 Our results clarify the functional
role of Phf8 in mammalian development and behaviour and
148 Lysosomal distribution is linked to the
role of lysosomes in many cellular functions, including
149 The important
role of vesicles in many aspects of cell function is wel
150 teractions and the evidence for an important
role of IL-6 in mediating allograft rejection.
151 Thus, these studies identify the critical
role of KLF15 in mediating the salutary effects of gluco
152 partitioning of TMDs and support the central
role of rafts in membrane traffic.
153 Our results provide support for the
role of oscillatory reinstatement in memory retrieval.SI
154 on with a waxing and waning of interest, the
role of sleep in memory processing remains controversial
155 nerative diseases due in part to the central
role of mitochondria in metabolism, ROS regulation, and
156 The fundamental
role of AOX in metabolizing xenobiotics is also due to t
157 ar interactions important for the regulatory
roles of MAP2c in microtubule dynamics.
158 results provide insights into the potential
role of mineral surfaces in mimicking aspects of biochem
159 Although the
role of CL in mitochondrial function, biogenesis, and ge
160 These results focus attention on the
role of EHF in modifying CF lung disease severity.
161 and invasion, suggesting an ATGL-independent
role of ABHD5 in modulating PCa aggressiveness.
162 Here, we provide evidence for a novel
role of CTRP6 in modulating both inflammation and insuli
163 Here we investigated the
role of exogenous ABA in modulating thrombopoiesis, the
164 c and diabetic islets, suggesting a positive
role of linagliptin in modulating alpha cell function to
165 ose of the present study was to evaluate the
roles of CAFs in modulating tumor vasculature, chemoresi
166 f MPM patients with a focus on the expanding
role of MMT in MPM.
167 The present work shows the
role of SOCS1 in murine melanoma development and the pot
168 The
roles of these receptors in myeloid cells during B cell
169 We found no convincing evidence for a direct
role of vitamin D in myopia risk.
170 deed, very few studies have investigated the
role of plant toxins in nectar for defense against necta
171 Emerging
role of dopamine in neovascularization of pheochromocyto
172 To study the
role of Copb2 in neural development, we utilized genome-
173 novo protein design as well as defining the
role of protein misfolding in neurodegenerative disorder
174 and traumatic brain injury, though the exact
role of the immunoproteasome in neuropathology remains p
175 This review discusses the
role of astrocytes in neurovascular signalling in both p
176 The
role of temozolomide chemotherapy in newly diagnosed 1p/
177 nsight into understanding the alteration and
role of MEG3 in nickel-induced lung tumorigenesis.
178 review article, we will first review the key
role of Ca(2+) in normal cardiac function-in particular,
179 logical significance because of the critical
role of folate in normal cell function and the wide rang
180 rk provides an improved understanding of the
role of ionic correlations in NP assembly and design rul
181 e investigated the functional and prognostic
role of TRIM14 in NSCLC using in vitro and in vivo pertu
182 c electrostatic interactions, supporting the
role of XRCC1 in nuclear cotransport of APLF.
183 sphorylation on AID serine38 (pS38), but the
role of pS38 in off-target activity has not been evaluat
184 m implementation, and the current and future
role of home monitoring in ophthalmology.
185 ription of protein-coding genes has left the
roles of Pol III in organismal physiology relatively une
186 These findings reveal a novel
role of HNF-1beta in osmoregulation and identify multipl
187 The present study determined the
role of HOTAIR in pancreatic cancer TRAIL resistance and
188 uccessfully remove the virus and examine the
role of the virus in parasitemia and the pathogenesis of
189 significant enteric pathogen of humans, the
roles of these regulators in pathogenesis are less known
190 ession to CCC, but little is known about the
role of epigenetic modifications in pathological gene ex
191 been used and provided evidence for the key
role of serotonergic pathology in patients with Parkinso
192 The study evaluated the
role of TCZ in patients with noninfectious uveitis (NIU)
193 d on what has been established regarding the
role of the microbiome in patients with asthma, atopic d
194 ion in multiple PCa cell lines, suggesting a
role of KPNA4 in PCa progression.
195 contrast, barely anything is known about the
role of glycylation in primary cilia because of limitati
196 yeast Saccharomyces cerevisiae However, the
roles of Msn2/4 in primary metabolic pathways such as fa
197 ar prion protein, leading us to question the
role of fH in prion disease.
198 Thus, we have identified an important
role of TCTP in promoting DNA double-stand break repair
199 , our results elucidate the tumor-suppressor
role of SPOP in prostate cancer in which it acts as a ne
200 hus provides direct evidence for the crucial
role of Nrf2 in protecting human organ function (i.e., s
201 onverbal social behaviors, and highlight the
role of human attachment in providing a template for two
202 ditions in Arabidopsis thaliana The possible
role of zeaxanthin in PSI photoprotection is discussed.
203 factor-1alpha (HIF-1alpha) is increased, the
role of HIF-1alpha in pulmonary artery smooth muscle cel
204 To test the
role of the RMTg in punished reward seeking, adult male
205 These data support a
role of the amygdala in recovery from depression.
206 Our results uncover a novel
role of GRP78 in reducing prion pathogenesis, suggesting
207 ion of early B and pro-B cells, suggesting a
role of AHR in regulating B lymphopoiesis.
208 We also reveal a
role of Crem in regulating striatal structural plasticit
209 However, failing to recognize the additional
role of environmental factors in regulating birth and mo
210 A new
role of EPiR in regulating the developmental responses o
211 to deciphering the mechanisms underlying the
role of FCSCs in regulating bone formation.
212 f angiogenesis by TLRs and confirm a central
role of Fli1 in regulating vascular homeostasis.
213 ng yeast nucleus, demonstrates the conserved
role of genome architecture in regulating DNA replicatio
214 The
role of hormones in regulating corneal tissue structure
215 kinases is of particular interest due to the
role of these kinases in regulating resistance to beta-l
216 However, the
role of this gradient in regulating tissue size is a top
217 genic translocations as well as a functional
role of TOP2A cleavage in regulating transcription elong
218 The
role of FXR in regulation of bile acid synthesis and hep
219 To test the
role of nuclear surveillance in reprogramming gene expre
220 tudy aimed to determine the osteoclastogenic
role of H4R in rheumatoid arthritis (RA).
221 Here, we explore the
role of natural selection in shaping the processes that
222 s steady-state output level, and analyze the
role of network design in shaping this diversity from ge
223 for noncoding sequences, suggesting a larger
role of splicing coordination in shaping proteins.
224 is in other vertebrates, we investigated the
role of RFRP-3 in social reproductive suppression in NMR
225 Understanding the
role of this mechanism in specific circuits requires ide
226 s GC precursor fate in Arabidopsis The novel
role of BdMUTE in specifying lateral SCs appears linked
227 ualism and acting can help us understand the
role of gesture in spoken/sign language.
228 The
role of space charges in stabilizing polarization gradie
229 should be conducted to explore the critical
role of CAR in survival of cancer patients.
230 smission and provide novel insights into the
role of Unc-104 in synapse maturation.
231 The
role of mature domains in targeting and secretion is unc
232 e our understanding of vRNA assembly and the
role of cytoskeletal proteins in that process.
233 The
role of AP-2 in the maintenance of proper apical membran
234 provides a blueprint for characterizing the
role of bacteria in the host response to chemotherapeuti
235 Role of cardiotrophin-1 in the regulation of metabolic c
236 ovided direct evidence for understanding the
role of CNTs/MnO2 in the lithiation process used in lith
237 maging in Drosophila embryos, we dissect the
role of condensin I in the maintenance of mitotic chromo
238 The
role of electrostatic interactions in the formation of l
239 Here we studied the
role of ELMO1 in the fate of internalized targets.
240 To understand the
role of EMP2 in the etiology of disease, gene analysis w
241 sets and uncover a previously unappreciated
role of epigenome deregulation in the genesis of 13% of
242 Herein, we analyzed the
role of exosomes in the differentiation of HT29 cells.
243 In conclusion, these findings underline the
role of fat content in the diet in altering gut microbio
244 The
role of fetal hepcidin in the regulation of placental ir
245 gether, our results provide insight into the
role of gene expression in the susceptibility of complex
246 e bathypelagic layer, indicating the central
role of heterotrophy in the dark ocean.
247 To determine the
role of HPV in the regional perfusion redistribution in
248 We assessed the
role of IL-33 in the augmented effects of ozone observed
249 The
role of ions in the fungal decay process of lignocellulo
250 Yet, the evidence is uncertain regarding the
role of iron in the development of gestational diabetes
251 ts new questions regarding the controversial
role of lactate in the brain.
252 or cirrhotic livers, suggesting an important
role of liver fibrosis in the premalignant environment (
253 These findings revealed an essential
role of LRRK in the survival of DA neurons and in the re
254 ity of the cells to paclitaxel, suggesting a
role of mechanotransduction in the evolution of drug res
255 These findings demonstrate the functional
role of miR-146b in the chondrogenic differentiation of
256 hybridization was performed to determine the
role of MT in the assembly of multiple vRNA segments.
257 We examined the
role of neuroimaging in the setting of autoimmune enceph
258 y sensory entrainment, supporting a critical
role of ongoing oscillations in the integration/segregat
259 Future investigations should focus on the
role of Pax3+ cells in the diaphragm during adaptation t
260 ally, the 2009 IAV pandemics highlighted the
role of pigs in the emergence of IAVs with pandemic pote
261 Here, we evaluated the
role of prolactin action in the MPOA using complementary
262 However, the functional
role of RavA-ViaA in the cell is not yet well establishe
263 The results advance our knowledge on the
role of sensory input in the generation of the neural dr
264 Here, we review the
role of SERT in the development of motor and nonmotor co
265 a cell proliferation and suggest a potential
role of SLC13A5 in the progression of human hepatocellul
266 ovided fundamental information regarding the
role of substrate oxidation in the development of obesit
267 Our results highlight the beneficial
role of sulfur vacancies in the electrocatalytic perform
268 In this study, we focused on the
role of T cells in the maintenance/survival of the matur
269 However, the functional
role of the TJ in the glomerular podocyte is unclear.
270 These sex differences in the
role of these prostanoids in the PVAT-induced contractio
271 remained elusive, maintaining enigmatic the
role of this gene in the human embryo.
272 tiation of P19 cells, suggesting a conserved
role of this kinase in the epigenic activation of MOR in
273 ether, these findings demonstrate regulatory
roles of ASHCEs in the creation of avian-specific traits
274 However, the in vivo
roles of TFEB in the mammalian intestinal epithelium wer
275 lobally can improve our understanding of the
roles of wetlands in the global C cycle.
276 and motility, but little is known about the
role of EGFR in these mechanosensing processes.
277 To determine the
role of OCT3 blockade in these effects, we examined the
278 The potential
role of AMPK in this setting is widely unknown.
279 However, the precise
role of BM in this axis remains unknown.
280 d show efficacy in multiple cancers, but the
role of costimulatory molecules in this T cell rescue re
281 tion of TH2 differentiation and the critical
role of GATA-3 in this process.
282 y associated with CDR formation, whereas the
role of other GTPases in this process is either lacking
283 The key
role of tyrosine kinases in this process is further subs
284 However, the
role of Mac-1 in thrombosis is undefined.
285 approximately 0.4-0.5) suggest an important
role of sulfate in tracer formation via both physical an
286 will review recent literature regarding the
role of lncRNAs in transcriptional control of inflammato
287 ed in biomarker discovery studies, while the
role of MS in translating biomarker candidates to clinic
288 However, little is known about the
role of bat ectoparasites in transmitting and maintainin
289 Taken together, we demonstrate a novel
role of proteasome inhibitors in treating radiation-indu
290 In the present study, we outline the
role of Dll4 in Treg cell differentiation, stability, an
291 Although the
role of 5-LO in tumor cells is beginning to emerge, with
292 equisite in epithelial tumor initiation, the
roles of CDC42 in tumorigenesis are still poorly underst
293 Recently, the
roles of FAM83H in tumorigenesis have been interested an
294 ool for investigating the pathophysiological
roles of lymphocytes in various diseases including cance
295 We next examined a potential
role of PTP1B in VEGF-induced angiogenesis.
296 The
role of CTD phosphorylation in virion secretion, if any,
297 Our results describing the
role of MT in vRNA transport and assembly expand upon pr
298 nnels in VSMCs and are the first to show the
role of Homer proteins in VSMCs and its importance in ne
299 Due to the central
role of skeletal muscle in whole-body metabolism, we aim
300 e inconsistencies preclude assessment of the
role of LBR in Xist spreading.