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1                               We capture the role of the linker in a heuristic scaling model, and we
2 se findings confirm the important regulatory roles of AlucJHEH in A. lucorum and indicate this gene a
3                         These results reveal roles of gap junctions in a complex behavior at cellular
4 ollectively, these results reveal a critical role of miR-122 in acetaminophen detoxification and impl
5 ctor target; however, the pathophysiological role of mitochondria in ADPKD remains uncharacterized.
6           In this study, we investigated the role of RARRES2 in adrenocortical carcinoma (ACC), a rar
7                                 However, the role of calpain in airway smooth muscle remodelling rema
8                                 However, the role of this pathway in allo-HCT is previously unknown.
9 e been well-characterised, but the potential role of these alkaloids in animal pathogenesis has not b
10 rmance parameters for coated MNs include the role of excipients in assisting dissolution from the MNs
11 ; describes existing evidence supporting the role of LOX-1 in atherogenesis and its major complicatio
12                              We examined the role of vascular CXCR4 in atherosclerosis and plaque com
13                     Until recently, the dual roles of mitochondria in ATP production (bioenergetics)
14     Previous reports pointed to the probable role of COPT2 in Au transport based on the transcript ac
15 ysialylation flank the PBR, we evaluated the role of PBR residues in autopolysialylation and found th
16 ase virus (IBDV) was used to investigate the role of autophagy in avibirnavirus replication.
17                                          The role of Hap10 in BD pathogenesis is unknown.
18                                          The role of alternative splicing in beta cells remains uncle
19 lation, serving as a paradigm to explore the role of linker histones in bio-signaling processes.
20                     For each, we discuss the role of microbiota in biogeochemical cycling and outline
21  greatly facilitate our understanding of the role of BMP in biological systems.
22 , and vascular levels, but the cell-specific role of Nox2 in BP regulation is unknown.
23 f these disorders helps us to understand the role of chromatin regulators in brain development, plast
24 ich may contribute to the pathophysiological role of neuroligins in brain disorders.
25                             We addressed the role of ROS in C57BL/6 mice following intradermal infect
26 erved in CAEBV and that implies an important role of monocytes in CAEBV.
27     There has been controversy regarding the role of AMPK in cancer, some of which may be due to func
28      Although many studies have examined the role of chronic inflammation in cancer development, few
29  within proteins as a signal for the driving role of mutations in cancer.
30 ing an additional transcriptional activation role of MYC in cancer metabolism.
31 provide functional evidence for an essential role of oxidative phosphorylation in cancer.
32 solve the paradox, highlighting a regulatory role of telomeres in cancer.
33                   We sought to determine the role of gamma2-AMPK in cardiac stress response using bio
34 ccompanying paper focuses on the integrative role of K(+) channels in cardiac electrophysiology, i.e.
35          Here, we investigated the potential role of NDPK-C in cardiac cAMP formation and contractili
36                  This manuscript reviews the role of the ECM in cardiac repair and remodeling and dis
37 d to enhance our understanding regarding the role of the latter in cardiac physiology and relevant di
38 nheimer" enzymes) have been used to test the role of protein dynamics in catalysis.
39                     Here, we reevaluated the role of RelB in cDC and myeloid development using a seri
40 CD11c(+) cells, and highlights the important role of SWAP-70 in Cer dynamics in dendritic cells.
41  and radiotherapy, little is known about the role of histone expression in chemoresistance.
42 ed epithelial cells, signifying an important role of CAF exosomes in chemotherapeutic drug resistance
43                                          The role of germline mutations in children and adults with h
44 tural protein) were generated to explore the role of this protein in chromatin structure and cardiac
45 tion mediators and shedding new light on the role of fibroblasts in chronic inflammation.
46 inase 1/3, this study aimed to establish the role of RIP3 in chronic cardiac allograft rejection.
47 3 ratio is an important consideration in the role of FAs in cognitive function, and the optimal balan
48             These observations elucidate the role of roughness in colloid attachment under both favor
49 hich will foster future investigation of the role of mesentery fat in colorectal diseases.
50 nts, timing, and kinetics of the multivalent role of ubiquitin signals in control of amplitude and se
51                     The potential protective role of B cells in controlling cCMV-related disease and
52                                  The central role of protein kinases in controlling disease processes
53                                          The role of species interactions in controlling the interpla
54  this species, indicating a highly conserved role of this protein in controlling organ size.
55                     To analyze the potential role of Tregs in controlling the TCR repertoire breadth
56     This study was conducted to identify the role of Scx in cortical bone development and fracture he
57                            To understand the role of oncogenic KRAS in CRC, we engineered a mouse mod
58              This corroborates the mediating role of attention in crowding out.
59                          We investigated the role of skin microbiota in cutaneous leishmaniasis and f
60 induced myocarditis, we aimed to unravel the role of NOD2 in CVB3-induced myocarditis.
61       Increasing evidence suggests a crucial role of inflammation in cytokine-mediated beta-cell dysf
62                           To investigate the role of clathrin in DCV biogenesis, we stably transduced
63                                  To test the role of Gank in degradation of CUGBP1, we generated mice
64 ive-like behaviors, pointing to an important role of this phosphatase in depression.
65 abnormalities, and we sought to evaluate the role of CMR in determining sudden cardiac arrest pathoge
66 ecent "magic ratio rules", which capture the role of connectivity in determining the electrical condu
67              This study aims to identify the role of IRF6 in development of exocrine glands, specific
68  Accumulating evidence suggests the critical role of mGluR2/3 in different aspects of nicotine addict
69 hanistic and functional understanding of the role of PARPs in different biological processes has grow
70       The data demonstrate fundamentally new roles of TMEM16A in differentiated epithelial cells: TME
71               A growing understanding of the role of DAMPs in directing the immune response to transp
72                           To investigate the role of BH4 deficiency in disease phenotypes, 12-month-o
73 ing of habitats makes them ideal to test the role of environmental pressure in driving ecological and
74 ng differentiation, confirming the causative role of Fus3 dynamics in driving cell fate decisions.
75          These results show evidence for the role of prey heterogeneity in driving functional complem
76 itivity of cancer cells, consistent with the role of hPXR in drug resistance.
77 le reviews the literature and summarizes the role of inflammation in dry eye disease.
78                                          The role of adaptive immunity in early cancer development is
79 ion and provides insight into the protective role of C1q in early atherosclerosis.
80 tic/epigenetic investigations to explore the role of miRNA in early stage BC in young women, includin
81    New technologies that help to unravel the role of ambient aerosols in earth climate and to assess
82 here has been some progress in revealing the role of epigenetics in ecological processes, studies wit
83  less bone formation, indicating a prominent role of DA in effective bone regeneration.
84 ntrast, our results indicate a much stronger role of temperature in embryonic development time than c
85                            Understanding the role of neurons in encoding and transmitting information
86 DF on clock gene transcription and the known role of PDF in enhancing PER/TIM stability occur via ind
87        In order to systematically detect the role of phenotypic variability in enteropathogenic E. co
88                    In this short review, the roles of miRNA in epidermal development, psoriasis, cuta
89 ful in the further elucidation of the causal role of reflux in erosive tooth wear.
90 , which underscore a potentially significant role of 5RK in exocytosis, we next amperometrically anal
91  in the cell identify a potential regulatory role of ACPS in fatty acid biosynthesis.
92                                 However, the role of Scx in fracture healing has not yet been explore
93 n of tissue-specific gene expression and the role of gene duplication in functional novelty, but its
94 r outcomes 90 days after ICH, confirming the role of TGF-beta1 in functional recovery from ICH.
95 sion and metastasis of some cancers, but the role of FPR2 in gastric cancer (GC) has not yet been elu
96                    To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene kno
97 vations contribute to an appreciation of the roles of splice isoforms in genetic disorders and sugges
98                     To better understand the roles of microRNAs in glial function, we used a conditio
99                                          The role of calcium regulators in governing these processes
100 Collectively, our study demonstrates a novel role of FANCD2 in governing cellular ATP production, and
101             These results establish dominant roles of AMPARs in governing bidirectional synaptic and
102                                          The role of mutations in GP and NP is not clear.
103 were identified almost a decade ago, yet the role of repulsive interactions in guiding structure form
104  in further elucidation of the physiological role of FPR2 in health and disease.
105                    To describe the expanding role of telemedicine in healthcare, the key criteria req
106                             To determine the role of ILK in hepatic insulin action in vivo, male C57B
107                                 However, the role of TGR5 in hepatic metabolism has not been explored
108 also enhanced by LY6E, suggesting additional roles of LY6E in HIV-1 replication.
109 otential to improve our understanding of the role of global methylation in human diseases, especially
110                                          The role of neuronal oscillations in human somatosensory per
111 ed for the first time, to our knowledge, the role of PIKfyve in human and mouse neutrophils.
112                                 However, the role of this cascade in human HCC remains unclear.
113                           To investigate the role of YAP1 in human eye development, we performed in s
114 ion and facilitate efforts to understand the roles of microglia in human brain diseases.
115                    To evaluate the potential role of these residues in hydrophobic gating, Leu267 and
116                            The physiological role of these proteins in IFN-gamma signaling has not be
117                     We discuss the potential role of these biofilms in ikaite column formation.
118 groundwork for future studies to explore the role of DNA replication in immune cell generation and fu
119                    Therefore, the biological role of CCRL2 in immunity is still unclear.
120 ides a specific mechanism accounting for the role of IFN-alpha in immunosuppression and predicts that
121 ects of this material have been studied, the role of defects in improving the energy storage density
122                The available evidence on the role of arsenic metabolism in individual susceptibility
123 ts also impose restrictions on the potential role of atmospheric CO2 in inferred warmer conditions an
124 olutionary model of inteins and a functional role of HEN domains in inteins.
125 les-based approaches, and highlights the key role of these calculations in interpreting increasingly
126 d by ubiquitylation and acetylation, but the role of this residue in intrinsic KRAS function has not
127 To date there is no clear information on the role of VEGF-A in IPF.
128                          We investigated the role of Act1 in keratinocyte responses to IL-17 using a
129    Replication studies and understanding the roles of these genes in keratoconus are warranted.
130                           We then tested the role of JAK2/STAT3 in ketamine-induced plasticity in the
131     Whereas another review will focus on the role of Runx factors in leukemias, this review will prov
132                           Given the critical role of BCRP in limiting fetal exposure to drugs and xen
133 c oral epithelium ( Irf6 cKO), bypassing the role of the gene in lip and palate morphogenesis and thu
134 anel of lipid-associated genes, indicating a role of SLC7A11 in lipid metabolism.
135       In conclusion, we present an oncogenic role of FAM83H in liver cancer, which is closely associa
136 ken together, our study has revealed a novel role of GSK3 in liver regeneration after APAP overdose a
137 motes the release of AA, we investigated the role of PLA2 in local and systemic disease during S. pne
138                                 To study the role of neutrophils in LPS-induced endotoxemia, we devel
139                   To further investigate the role of inflammation in lung carcinogenesis, we evaluate
140 bset of T cells with cytotoxic function, the role of which in lung immunity is unclear.
141 s review, we present current concepts on the role of clonal evolution in lymphoid and myeloid leukemi
142 he late-blooming phase, suggesting an active role of this group in lysing P. donghaiense cells.
143                    Here, we investigated the role of HCA2 in macrophage-mediated inflammation and the
144           These results confirm the critical role of parrotfish in maintaining coral-dominated reef h
145                This review will focus on the role of cell death in maintenance of T-cell homeostasis
146                      Although the pathogenic role of Mycoplasma genitalium in male urethritis is clea
147           Our results clarify the functional role of Phf8 in mammalian development and behaviour and
148      Lysosomal distribution is linked to the role of lysosomes in many cellular functions, including
149                                The important role of vesicles in many aspects of cell function is wel
150 teractions and the evidence for an important role of IL-6 in mediating allograft rejection.
151    Thus, these studies identify the critical role of KLF15 in mediating the salutary effects of gluco
152 partitioning of TMDs and support the central role of rafts in membrane traffic.
153          Our results provide support for the role of oscillatory reinstatement in memory retrieval.SI
154 on with a waxing and waning of interest, the role of sleep in memory processing remains controversial
155 nerative diseases due in part to the central role of mitochondria in metabolism, ROS regulation, and
156                              The fundamental role of AOX in metabolizing xenobiotics is also due to t
157 ar interactions important for the regulatory roles of MAP2c in microtubule dynamics.
158  results provide insights into the potential role of mineral surfaces in mimicking aspects of biochem
159                                 Although the role of CL in mitochondrial function, biogenesis, and ge
160         These results focus attention on the role of EHF in modifying CF lung disease severity.
161 and invasion, suggesting an ATGL-independent role of ABHD5 in modulating PCa aggressiveness.
162        Here, we provide evidence for a novel role of CTRP6 in modulating both inflammation and insuli
163                     Here we investigated the role of exogenous ABA in modulating thrombopoiesis, the
164 c and diabetic islets, suggesting a positive role of linagliptin in modulating alpha cell function to
165 ose of the present study was to evaluate the roles of CAFs in modulating tumor vasculature, chemoresi
166 f MPM patients with a focus on the expanding role of MMT in MPM.
167                   The present work shows the role of SOCS1 in murine melanoma development and the pot
168                                          The roles of these receptors in myeloid cells during B cell
169 We found no convincing evidence for a direct role of vitamin D in myopia risk.
170 deed, very few studies have investigated the role of plant toxins in nectar for defense against necta
171                                     Emerging role of dopamine in neovascularization of pheochromocyto
172                                 To study the role of Copb2 in neural development, we utilized genome-
173  novo protein design as well as defining the role of protein misfolding in neurodegenerative disorder
174 and traumatic brain injury, though the exact role of the immunoproteasome in neuropathology remains p
175                    This review discusses the role of astrocytes in neurovascular signalling in both p
176                                          The role of temozolomide chemotherapy in newly diagnosed 1p/
177 nsight into understanding the alteration and role of MEG3 in nickel-induced lung tumorigenesis.
178 review article, we will first review the key role of Ca(2+) in normal cardiac function-in particular,
179 logical significance because of the critical role of folate in normal cell function and the wide rang
180 rk provides an improved understanding of the role of ionic correlations in NP assembly and design rul
181 e investigated the functional and prognostic role of TRIM14 in NSCLC using in vitro and in vivo pertu
182 c electrostatic interactions, supporting the role of XRCC1 in nuclear cotransport of APLF.
183 sphorylation on AID serine38 (pS38), but the role of pS38 in off-target activity has not been evaluat
184 m implementation, and the current and future role of home monitoring in ophthalmology.
185 ription of protein-coding genes has left the roles of Pol III in organismal physiology relatively une
186                These findings reveal a novel role of HNF-1beta in osmoregulation and identify multipl
187             The present study determined the role of HOTAIR in pancreatic cancer TRAIL resistance and
188 uccessfully remove the virus and examine the role of the virus in parasitemia and the pathogenesis of
189  significant enteric pathogen of humans, the roles of these regulators in pathogenesis are less known
190 ession to CCC, but little is known about the role of epigenetic modifications in pathological gene ex
191  been used and provided evidence for the key role of serotonergic pathology in patients with Parkinso
192                      The study evaluated the role of TCZ in patients with noninfectious uveitis (NIU)
193 d on what has been established regarding the role of the microbiome in patients with asthma, atopic d
194 ion in multiple PCa cell lines, suggesting a role of KPNA4 in PCa progression.
195 contrast, barely anything is known about the role of glycylation in primary cilia because of limitati
196  yeast Saccharomyces cerevisiae However, the roles of Msn2/4 in primary metabolic pathways such as fa
197 ar prion protein, leading us to question the role of fH in prion disease.
198        Thus, we have identified an important role of TCTP in promoting DNA double-stand break repair
199 , our results elucidate the tumor-suppressor role of SPOP in prostate cancer in which it acts as a ne
200 hus provides direct evidence for the crucial role of Nrf2 in protecting human organ function (i.e., s
201 onverbal social behaviors, and highlight the role of human attachment in providing a template for two
202 ditions in Arabidopsis thaliana The possible role of zeaxanthin in PSI photoprotection is discussed.
203 factor-1alpha (HIF-1alpha) is increased, the role of HIF-1alpha in pulmonary artery smooth muscle cel
204                                  To test the role of the RMTg in punished reward seeking, adult male
205                         These data support a role of the amygdala in recovery from depression.
206                  Our results uncover a novel role of GRP78 in reducing prion pathogenesis, suggesting
207 ion of early B and pro-B cells, suggesting a role of AHR in regulating B lymphopoiesis.
208                             We also reveal a role of Crem in regulating striatal structural plasticit
209 However, failing to recognize the additional role of environmental factors in regulating birth and mo
210                                        A new role of EPiR in regulating the developmental responses o
211 to deciphering the mechanisms underlying the role of FCSCs in regulating bone formation.
212 f angiogenesis by TLRs and confirm a central role of Fli1 in regulating vascular homeostasis.
213 ng yeast nucleus, demonstrates the conserved role of genome architecture in regulating DNA replicatio
214                                          The role of hormones in regulating corneal tissue structure
215 kinases is of particular interest due to the role of these kinases in regulating resistance to beta-l
216                                 However, the role of this gradient in regulating tissue size is a top
217 genic translocations as well as a functional role of TOP2A cleavage in regulating transcription elong
218                                          The role of FXR in regulation of bile acid synthesis and hep
219                                  To test the role of nuclear surveillance in reprogramming gene expre
220 tudy aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA).
221                         Here, we explore the role of natural selection in shaping the processes that
222 s steady-state output level, and analyze the role of network design in shaping this diversity from ge
223 for noncoding sequences, suggesting a larger role of splicing coordination in shaping proteins.
224 is in other vertebrates, we investigated the role of RFRP-3 in social reproductive suppression in NMR
225                            Understanding the role of this mechanism in specific circuits requires ide
226 s GC precursor fate in Arabidopsis The novel role of BdMUTE in specifying lateral SCs appears linked
227 ualism and acting can help us understand the role of gesture in spoken/sign language.
228                                          The role of space charges in stabilizing polarization gradie
229  should be conducted to explore the critical role of CAR in survival of cancer patients.
230 smission and provide novel insights into the role of Unc-104 in synapse maturation.
231                                          The role of mature domains in targeting and secretion is unc
232 e our understanding of vRNA assembly and the role of cytoskeletal proteins in that process.
233                                          The role of AP-2 in the maintenance of proper apical membran
234  provides a blueprint for characterizing the role of bacteria in the host response to chemotherapeuti
235                                              Role of cardiotrophin-1 in the regulation of metabolic c
236 ovided direct evidence for understanding the role of CNTs/MnO2 in the lithiation process used in lith
237 maging in Drosophila embryos, we dissect the role of condensin I in the maintenance of mitotic chromo
238                                          The role of electrostatic interactions in the formation of l
239                          Here we studied the role of ELMO1 in the fate of internalized targets.
240                            To understand the role of EMP2 in the etiology of disease, gene analysis w
241  sets and uncover a previously unappreciated role of epigenome deregulation in the genesis of 13% of
242                      Herein, we analyzed the role of exosomes in the differentiation of HT29 cells.
243  In conclusion, these findings underline the role of fat content in the diet in altering gut microbio
244                                          The role of fetal hepcidin in the regulation of placental ir
245 gether, our results provide insight into the role of gene expression in the susceptibility of complex
246 e bathypelagic layer, indicating the central role of heterotrophy in the dark ocean.
247                             To determine the role of HPV in the regional perfusion redistribution in
248                              We assessed the role of IL-33 in the augmented effects of ozone observed
249                                          The role of ions in the fungal decay process of lignocellulo
250 Yet, the evidence is uncertain regarding the role of iron in the development of gestational diabetes
251 ts new questions regarding the controversial role of lactate in the brain.
252 or cirrhotic livers, suggesting an important role of liver fibrosis in the premalignant environment (
253         These findings revealed an essential role of LRRK in the survival of DA neurons and in the re
254 ity of the cells to paclitaxel, suggesting a role of mechanotransduction in the evolution of drug res
255    These findings demonstrate the functional role of miR-146b in the chondrogenic differentiation of
256 hybridization was performed to determine the role of MT in the assembly of multiple vRNA segments.
257                              We examined the role of neuroimaging in the setting of autoimmune enceph
258 y sensory entrainment, supporting a critical role of ongoing oscillations in the integration/segregat
259    Future investigations should focus on the role of Pax3+ cells in the diaphragm during adaptation t
260 ally, the 2009 IAV pandemics highlighted the role of pigs in the emergence of IAVs with pandemic pote
261                       Here, we evaluated the role of prolactin action in the MPOA using complementary
262                      However, the functional role of RavA-ViaA in the cell is not yet well establishe
263     The results advance our knowledge on the role of sensory input in the generation of the neural dr
264                          Here, we review the role of SERT in the development of motor and nonmotor co
265 a cell proliferation and suggest a potential role of SLC13A5 in the progression of human hepatocellul
266 ovided fundamental information regarding the role of substrate oxidation in the development of obesit
267         Our results highlight the beneficial role of sulfur vacancies in the electrocatalytic perform
268             In this study, we focused on the role of T cells in the maintenance/survival of the matur
269                      However, the functional role of the TJ in the glomerular podocyte is unclear.
270                 These sex differences in the role of these prostanoids in the PVAT-induced contractio
271  remained elusive, maintaining enigmatic the role of this gene in the human embryo.
272 tiation of P19 cells, suggesting a conserved role of this kinase in the epigenic activation of MOR in
273 ether, these findings demonstrate regulatory roles of ASHCEs in the creation of avian-specific traits
274                         However, the in vivo roles of TFEB in the mammalian intestinal epithelium wer
275 lobally can improve our understanding of the roles of wetlands in the global C cycle.
276  and motility, but little is known about the role of EGFR in these mechanosensing processes.
277                             To determine the role of OCT3 blockade in these effects, we examined the
278                                The potential role of AMPK in this setting is widely unknown.
279                         However, the precise role of BM in this axis remains unknown.
280 d show efficacy in multiple cancers, but the role of costimulatory molecules in this T cell rescue re
281 tion of TH2 differentiation and the critical role of GATA-3 in this process.
282 y associated with CDR formation, whereas the role of other GTPases in this process is either lacking
283                                      The key role of tyrosine kinases in this process is further subs
284                                 However, the role of Mac-1 in thrombosis is undefined.
285  approximately 0.4-0.5) suggest an important role of sulfate in tracer formation via both physical an
286  will review recent literature regarding the role of lncRNAs in transcriptional control of inflammato
287 ed in biomarker discovery studies, while the role of MS in translating biomarker candidates to clinic
288           However, little is known about the role of bat ectoparasites in transmitting and maintainin
289       Taken together, we demonstrate a novel role of proteasome inhibitors in treating radiation-indu
290         In the present study, we outline the role of Dll4 in Treg cell differentiation, stability, an
291                                 Although the role of 5-LO in tumor cells is beginning to emerge, with
292 equisite in epithelial tumor initiation, the roles of CDC42 in tumorigenesis are still poorly underst
293                                Recently, the roles of FAM83H in tumorigenesis have been interested an
294 ool for investigating the pathophysiological roles of lymphocytes in various diseases including cance
295                 We next examined a potential role of PTP1B in VEGF-induced angiogenesis.
296                                          The role of CTD phosphorylation in virion secretion, if any,
297                   Our results describing the role of MT in vRNA transport and assembly expand upon pr
298 nnels in VSMCs and are the first to show the role of Homer proteins in VSMCs and its importance in ne
299                           Due to the central role of skeletal muscle in whole-body metabolism, we aim
300 e inconsistencies preclude assessment of the role of LBR in Xist spreading.

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