ライフサイエンスコーパス: rosacea

1 ow-up, we identified 5,462 incident cases of rosacea.

2 ent thinking about the parent disorder, acne rosacea.

3 nd 7.62 (95% CI, 6.78-8.57) in patients with rosacea.

4 lation and 4.99 (4.32-5.76) in patients with rosacea.

5 = 1.14-1.37), respectively, in patients with rosacea.

6 42.2 [16.5] years) were registered as having rosacea.

7 individuals, including 82,439 patients with rosacea.

8 nder TRPV4 a translational-medical target in rosacea.

9 influence of environmental factors affecting rosacea.

10 etinoin, are associated with improvements in rosacea.

11 and expectations of individuals affected by rosacea.

12 uture studies to better understand and treat rosacea.

13 eutrophils reach a maximum in papulopustular rosacea.

14 n underestimated hallmark in all subtypes of rosacea.

15 ciation between smoking and risk of incident rosacea.

16 therapy, and topical cyclosporine for ocular rosacea.

17 owed by a crescendo pattern toward phymatous rosacea.

18 urveyed regarding risk factors implicated in rosacea.

19 entarium for recalcitrant cases of childhood rosacea.

20 en different measures of smoking and risk of rosacea.

21 es such as psoriasis, atopic dermatitis, and rosacea.

22 as a critical element in the pathogenesis of rosacea.

23 cal protease involved in the pathogenesis of rosacea.

24 ilation and the inflammation associated with rosacea.

25 icacy and fewest adverse events for treating rosacea?

26 , contact lens wear in the setting of ocular rosacea (3 eyes), benzalkonium chloride toxicity (2 eyes

27 7] years) and 184 of the 68372 patients with rosacea (67.3% women; mean [SD] age, 42.2 [16.5] years).

28 Rosacea, a common facial skin disorder, has a poorly und

29 have been implicated in the pathogenesis of rosacea, a disorder treated by the use of low-dose doxyc

30 ection of the cathelicidin peptides found in rosacea, addition of SCTE, and increasing protease activ

31 ease in patients classified as having ocular rosacea (adjusted IRR, 2.03 [95% CI, 1.67-2.48]), and te

32 ed at significantly higher concentrations in rosacea-affected than in normal tear fluids.

33 trend = 0.003) and with a decreased risk of rosacea among current smokers (P for trend < 0.0001).

34 king was associated with an elevated risk of rosacea among past smokers (P for trend = 0.003) and wit

35 eligible for analysis; of these, 68 372 had rosacea and 5 416 538 constituted the reference populati

36 ons, we investigated the association between rosacea and dementia, including AD in Danish registers.

37 luid was collected from patients with ocular rosacea and normal control subjects.

38 olved non-genital-tract pathologies, such as rosacea and psoriasis.

39 nd as an immunomodulator in diseases such as rosacea and psoriasis.

40 We identified correlations between rosacea and UV radiation exposure, alcohol, smoking, ski

41 nformation on history of clinician-diagnosed rosacea and year of diagnosis was collected in 2005.

42 in the enhanced sensitivity of patients with rosacea, and observed that the epidermis of patients wit

43 pport the concept of a genetic component for rosacea, and provide candidate targets for future studie

44 th regards to etiology and therapy of ocular rosacea, and will also examine current thinking about th

45 ssed forms of cathelicidin peptides found in rosacea are different from those present in normal indiv

46 er smoking, we observed an increased risk of rosacea associated with past smoking (multivariable-adju

47 ndividuals and patients with dry eye who had rosacea-associated meibomian gland disease (MGD) or Sjog

48 in all except 1 patient who had significant rosacea blepharokeratoconjunctivitis, whose BCVA remaine

49 ea patients have signs or symptoms of ocular rosacea, but few cases were confirmed by an ophthalmolog

50 ited to patients with a primary diagnosis of rosacea by a hospital dermatologist (n = 5964), the adju

51 ggest an explanation for the pathogenesis of rosacea by demonstrating that an exacerbated innate immu

52 discovery group of 22,952 individuals (2,618 rosacea cases and 20,334 controls) was analyzed, leading

53 in a new group of 29,481 individuals (3,205 rosacea cases and 26,262 controls).

54 tion of the immune system in all subtypes of rosacea, characterizing erythematotelangiectatic rosacea

55 (BP), and chronic atopic and chronic ocular rosacea cicatrizing conjunctivitis; and normal human ser

56 as 1.71 (95%, CI 1.52-1.92) in patients with rosacea compared with the reference population.

57 Rosacea constitutes an independent risk factor for Parki

58 cea, characterizing erythematotelangiectatic rosacea (ETR) already as a disease with significant infl

59 with the erythematotelangiectatic subtype of rosacea (ETR).

60 Here we show that individuals with rosacea express abnormally high levels of cathelicidin i

61 observed that the epidermis of patients with rosacea expressed higher amounts of Toll-like receptor 2

62 he perifollicular inflammatory infiltrate of rosacea for both proteins.

63 ormal control subjects, patients with ocular rosacea had a greater delay of tear fluorescein clearanc

64 ecent articles on the pathogenesis of ocular rosacea have focused on the role of bacterial lipases, a

65 Therapies currently in vogue for ocular rosacea have not been rigorously studied with regards to

66 rimary initial diagnosis of acne vulgaris or rosacea in 2010.

67 Recent articles on the prevalence of ocular rosacea in patients with acne rosacea suggested that bet

68 proteins, were significantly associated with rosacea in the discovery group and confirmed in the repl

69 fluid obtained from 13 patients with ocular rosacea (including 1 patient with recurrent epithelial e

70 ng these antibiotics exclusively for acne or rosacea (indications that could be risk factors for brea

71 Rosacea is a chronic inflammatory skin disease whose pat

72 Ocular rosacea is a common and potentially blinding eye disorde

73 Rosacea is a common chronic inflammatory skin disease of

74 Rosacea is a common chronic inflammatory skin disorder w

75 Rosacea is a common skin disease that manifests unique i

76 Rosacea is a common, chronic skin disease that is curren

77 Acne rosacea is an inflammatory skin disease that affects 3%

78 tors influence rosacea, the genetic basis of rosacea is not established.

79 The relationship between smoking and rosacea is poorly understood.

80 Rosacea is significantly associated with dementia, parti

81 The pathogenesis of rosacea is unclear, but increased matrix metalloproteina

82 A-DRA and BTNL2 expression in papulopustular rosacea lesions from six individuals, including one with

83 /HNihrJaeBsmJ (KitW-sh) mice did not develop rosacea-like features.

84 in immunocompetent children with rosacea or rosacea-like refractory eruptions.

85 Elevated gelatinase B activity in ocular rosacea may be involved in the pathogenesis of the irrit

86 cognitive dysfunction in older patients with rosacea may be relevant.

87 ocus on neurologic symptoms in patients with rosacea may be warranted.

88 Prices of acne and rosacea medications increased a mean of 195%, and prices

89 lytic cathelicidin fragment LL37 in a murine rosacea model and that TRPV4 loss of function attenuates

90 leotide polymorphisms (SNPs) associated with rosacea, one of which replicated in a new group of 29,48

91 s with a hospital dermatologist diagnosis of rosacea only, the adjusted HRs of dementia and AD were 1

92 considered in immunocompetent children with rosacea or rosacea-like refractory eruptions.

93 tide that has been shown to be an enabler of rosacea pathogenesis.

94 cea suggested that between 6 and 18% of acne rosacea patients have signs or symptoms of ocular rosace

95 n of pro-MMP-9 (92 kDa) in the tear fluid of rosacea patients than controls.

96 e immunohistochemistry on facial biopsies of rosacea patients, classified according to their clinical

97 (MC) numbers are increased in the dermis of rosacea patients.

98 ogy, etiology, and optimal therapy of ocular rosacea remain to be determined, and will require a more

99 Faculty dermatologists determined a rosacea score for each twin participant according to the

100 2.46 and 42 fraternal twin pairs with a mean rosacea score of 0.75.

101 re were 233 identical twin pairs with a mean rosacea score of 2.46 and 42 fraternal twin pairs with a

102 nmelanoma skin cancer, dermatophytosis, acne rosacea, seborrheic keratosis, or warts; 74.1% of the su

103 h twin participant according to the National Rosacea Society (NRS) grading system.

104 a were confirmed on erythematotelangiectatic rosacea subjects who showed a decrease in matrix metallo

105 The NRS score and rosacea subtype were assessed using the NRS grading syst

106 ence of ocular rosacea in patients with acne rosacea suggested that between 6 and 18% of acne rosacea

107 m of gelatinase B was observed in 46% of the rosacea tear samples and none of the controls.

108 activity is greater in patients with ocular rosacea than in normal eyes.

109 Although environmental factors influence rosacea, the genetic basis of rosacea is not established

110 To our knowledge, this is the first study on rosacea to formally define genetic and environmental con

111 lation of activated MCs may be a therapy for rosacea treatment.

112 o presented with severe ocular and cutaneous rosacea unresponsive to oral doxycycline, oral isotretin

113 te ratio (95% CI) of glioma in patients with rosacea was 1.36 (1.18-1.58) in our primary analysis.

114 Rosacea was associated with a significantly increased ri

115 The risk of rosacea was significantly increased within 3-9 years sin

116 Comparatively few papers on ocular rosacea were published in the past year.

117 cells are increased in all three subtypes of rosacea, whereas neutrophils reach a maximum in papulopu

118 ly in the tear fluid of patients with ocular rosacea who had corneal epithelial disease.

119 h as acne, atopic dermatitis, psoriasis, and rosacea with an imbalance of the microflora even in the