ライフサイエンスコーパス: rot

1 in A (AntA), myxothiazol (Myx), or rotenone (Rot)).

2 he transcription factor repressor of toxins (Rot).

3 the transcription factor repressor of toxin (Rot).

4 y on crystalline cellulose (reduced in brown rot).

5 kidney (HEK) 293 cell using electrorotation (ROT).

6 aureus exoprotein expression (Sae) TCS, and Rot.

7 chitinases ChitA and ChitB during maize ear rot.

8 including increased incidence of blossom-end rot.

9 tional regulation of staphylococcal genes by Rot.

10 aroma precursors also increased during noble rot.

11 on largely via inactivation of the repressor Rot.

12 plant cell walls, a characteristic of white rot.

13 ng take-all and pythium and rhizoctonia root rots.

14 Rotational spinning in ROT-1' occurs at 97,000 s(-1) at 25 degrees C but is vir

15 Rot (3 mg/kg/day) was infused subcutaneously to male Lew

16 which is slower than the overall in plane (D(rot) = 3.2 rad(2)/ns) for the lipid molecule.

17 he promoter sequence of repressor of toxins (Rot), a master transcriptional regulator responsible for

18 n results from the Agr-mediated reduction in Rot activity rather than as a direct effect of the Agr s

19 We compared the transcriptional profile of a rot agr double mutant to that of its agr parental strain

20 bolomics approach, we demonstrate that noble rot alters the metabolism of cv Semillon berries by indu

21 ide host range for the ability to cause root rot and a very narrow host range for the ability to caus

22 Our data also indicate that Rot and agr have opposing effects on select target genes

23 ion of lignin has been well studied in white-rot and brown-rot fungi, but is much less well studied i

24 um rather than a dichotomy between the white-rot and brown-rot modes of wood decay.

25 ich also contains non-lignin-degrading brown rot and ectomycorrhizal species.

26 racted in parallel lineages leading to brown rot and mycorrhizal species.

27 inned berries, was a common outcome of noble rot and red-skinned berry ripening.

28 To delineate the interaction of rot and sae and the contribution of sarT to hla expressi

29 of sarT to hla expression, an assortment of rot and sae isogenic single mutants, a rot sae double mu

30 Here we demonstrate that Rot and SaeR, the response regulator of the Sae TCS, syn

31 The SarA homologs Rot and SarT were previously shown to be repressors of h

32 In vitro, abcA expression depends on rot and sarZ regulators.

33 Until now, Rot and the Sae TCS have been proposed to work in opposi

34 we have determined the crystal structure of Rot and used this information to probe the contribution

35 while limiting pythium and rhizoctonia root rots and fusarium root and crown rot in direct-seed syst

36 nization in intercellular spaces, leading to rotting and to the disruption of plant cell wall and mem

37 N(rot) and PSA were calculated with QikProp or Cerius2.

38 The relationship of rotatable bond count (N(rot)) and polar surface area (PSA) with oral bioavailabi

39 broad host-range pathogens that cause wilt, rot, and blackleg diseases on a wide range of plants.

40 le factors, including Agr, SarA, SarS, SarT, Rot, and MgrA.

41 pression of a key transcriptional regulator, Rot, and of several important exoproteins and surface fa

42 ct wild C. elegans population states in both rotting apples and reconstructed microbiomes: alpha-Prot

43 fusion due to a steeper length dependence, D(rot) approximately L(-)(3) versus D(trans) approximately

44 es without significant lignin removal (brown rot) are polyphyletic, having evolved multiple times fro

45 The role of Agr and Rot as regulators of ssl expression was observed across

46 During noble rot, B. cinerea induced the expression of key regulators

47 been classified as either white rot or brown rot, based on the ability (in white rot only) to degrade

48 nokaryotic strains PC9 and PC15 of the white rot basidiomycete Pleurotus ostreatus.

49 e laccase genes were isolated from the white-rot basidiomycete Trametes villosa (Tv).

50 Ca deficiency disorders such as blossom-end rot (BER) in tomato (Solanum lycopersicum) fruit may be

51 Blossom-end rot (BER) in tomato fruit (Solanum lycopersicum) is beli

52 Furthermore, blossom-end rot (BER) in tomato may be linked to changes in CAX acti

53 Evaluation of Rot binding to different activated and repressed promote

54 ffected by diseases such as sclerotinia stem rot, blackleg, and alternaria black spot resulting in si

55 benular nuclei in JP17 rats; the rat OT-bNP (rOT-bNP) transgene was not expressed in either line.

56 nvestigate this question, we determined that Rot bound to the protease promoters, and we observed tha

57 To assess the generality of the white-rot/brown-rot classification paradigm, we compared the g

58 The function of Rot, but not the transcription of rot, is regulated by t

59 llulose is a distinguishing feature of brown-rot, but the biochemical mechanisms and underlying genet

60 of a major pleiotropic transcription factor, Rot, by blocking its translation.

61 c electrostatic charge profile suggests that Rot can orient the WHTH domain to bind DNA.

62 h southern leaf blight and anthracnose stalk rot caused by Cochliobolis heterostrophus and Colletotri

63 nt plants were extremely susceptible to root rot caused by the fungal root pathogen Pythium mastophor

64 results of this work demonstrated that noble rot causes a major reprogramming of berry development an

65 protein production and pathogenicity in soft rot-causing Erwinia carotovora subsp. carotovora.

66 functional homologs of rsmB(Ecc) in non-soft-rot-causing Erwinia species, we cloned the rsmB genes of

67 sequence of carbohydrate removal among brown rot clades.

68 assess the generality of the white-rot/brown-rot classification paradigm, we compared the genomes of

69 Given the qualitative nature of the 'brown rot' classifier, we aimed to quantify and compare the te

70 us and the causal agent of anthracnose stalk rot, Colletotrichum graminicola.

71 es insight into a precise mechanism by which Rot controls virulence factor regulation in S. aureus.

72 Brown rot decay removes cellulose and hemicellulose from wood-

73 Rot did not affect the State 4Deltapsi of RBM and rat li

74 effects, suggesting for the first time that Rot differentially interacts with target promoters.

75 Surprisingly, we observed that Rot directly interacts with and activates the ssl promot

76 is pv. campestris, the causal agent of black rot disease of Brassica plants, possesses a specific sys

77 campestris (Xcc), the causal agent of black rot disease of Brassicaceae.

78 nic enterobacterium responsible for the soft rot disease of many plants of economic importance.

79 The impact of Lys12 on progression of root rot disease, together with the finding that similar gene

80 gely responsible for the elicitation of soft-rot diseases in plants and plant products.

81 ectate component of plant cell walls in soft rot diseases.

82 n evolutionary shift from white-rot to brown-rot during which the capacity for efficient depolymeriza

83 Soft-rot Enterobacteriaceae (SRE), which belong to the genera

84 In this issue of Developmental Cell, Rot et al. (2014) show that muscle and the fracture call

85 promoters revealed that certain mutations on Rot exhibit promoter-specific effects, suggesting for th

86 factor (sigma(B)) has a repressive effect on rot expression during the postexponential phase of growt

87 A modest upregulation of rot expression was also observed in sarS-negative strain

88 An upregulation of rot expression was observed during the stationary phase

89 Fusarium crown rot (FCR) of wheat and barley, predominantly caused by t

90 aminuria exhibit a body odour reminiscent of rotting fish, due to excessive excretion of trimethylami

91 um conicum were resistant to breakdown after rotting for extended periods or high-temperature acid tr

92 We named this ORF rot (for repressor of toxins) (GenBank accession no. AF1

93 The relative order of the values of k(rot) for different acyl groups parallels their reported

94 tational diffusion constants (D(trans) and D(rot)) for NRs were in good agreement with Tirado and Gar

95 r fruit fly larvae consume yeasts growing on rotting fruit and have evolved resistance to fermentatio

96 fungus Penicilium purpurogenum obtained from rotting fruit of the tree Averrhoa bilimbi growing in Sr

97 bacteria of C. elegans' natural habitats of rotting fruits and vegetation to provide greater context

98 cumented in the literature, although ripe or rotting fruits play an important role as a food or brood

99 Loss of Rot function during the postexponential phase of growth

100 he contribution made by specific residues to Rot function.

101 Secreted basidiomycete white-rot fungal laccases orchestrate this with high thermodyn

102 d proteins (one third of the predicted white-rot fungal proteome) in a single experiment, as one of t

103 The use of white rot fungi (WRF) for bioremediation of recalcitrant trace

104 s a heme-containing enzyme produced by white-rot fungi and is part of the extracellular lignin degrad

105 White rot fungi efficiently degrade lignin, a complex aromatic

106 Some white-rot fungi have been reported to lack LiP when grown on d

107 apable of substantial lignin decay are white rot fungi in the Agaricomycetes, which also contains non

108 Root rot fungi of the Heterobasidion annosum complex are the

109 Brown-rot fungi such as Postia placenta are common inhabitants

110 own rot of wood and that it may enable brown-rot fungi to degrade recalcitrant organopollutants.

111 To test the hypothesis that brown-rot fungi use extracellular free radical oxidants as bio

112 revious lignin biodegradation studies, white rot fungi were used to produce functional biopolymers fr

113 kely catalysts of ligninolysis in many white-rot fungi, because they have the unusual ability to depo

114 has been well studied in white-rot and brown-rot fungi, but is much less well studied in bacteria.

115 The technology has focused on the white rot fungi, which have complex extracellular ligninolytic

116 iomycetes, collectively referred to as white rot fungi.

117 ed multiple times from lignin-removing white rot fungi.

118 yketide synthase genes specific to the brown-rot fungi.

119 d PFCAs and polyfluorocarboxylic acids, wood-rotting fungi should be evaluated as potential candidate

120 The white-rot fungus Ceriporiopsis subvermispora delignifies ligno

121 terium Pseudomonas putida GB-1 and the white-rot fungus Coprinellus sp. The rate of Mn(II) oxidation,

122 pretreated with a medium dosage of the root rot fungus Heterobasidion annosum showed enhanced resist

123 promote the degradation of Azo dye by white-rot fungus Irpex lacteus CD2 in the lignin/dye/fungus sy

124 a copper metalloenzyme produced by the wood-rot fungus Phanerochaete chrysosporium as an essential c

125 Lignin peroxidases (LiP) from the white-rot fungus Phanerochaete chrysosporium oxidize veratryl

126 Comparisons with the closely related white-rot fungus Phanerochaete chrysosporium support an evolut

127 formed on Mn peroxidase (MnP) from the white-rot fungus Phanerochaete chrysosporium to investigate th

128 nd II of manganese peroxidase from the white-rot fungus Phanerochaete chrysosporium utilize the same

129 ted that manganese peroxidase from the white-rot fungus Phanerochaete chrysosporium was very suscepti

130 decomposition of carbamazepine by the white-rot fungus Pleurotus ostreatus in liquid culture compare

131 The white rot fungus Pleurotus ostreatus is able to completely rem

132 target screening for TPs formed by the white-rot fungus Pleurotus ostreatus.

133 Zn, in wood being decayed by the model brown rot fungus Serpula lacrymans.

134 This is a soft-rot fungus that may be contributing to wood degradation.

135 tructure that the principal degrader, a soft-rot fungus, mobilized the king's highly (15)N-enriched n

136 n of 6:2 FTOH [F(CF2)6CH2CH2OH] by the white-rot fungus, Phanerochaete chrysosporium, was investigate

137 he secretome of Pleurotus ostreatus, a white rot fungus.

138 emediation of environmental hazards by white-rot fungus.

139 parative and functional genomics of the "dry rot" fungus Serpula lacrymans, derived from forest ances

140 the dominant oxidant during incipient white rot had a half-life under 0.1 s.

141 We finally characterized the impact of noble rot in botrytized wines.

142 thocyanins is a consistent hallmark of noble rot in cv Semillon berries.

143 ctonia root rots and fusarium root and crown rot in direct-seed systems.

144 The transcriptional profiles of Rot in sigma(B)-positive and sigma(B)-negative strains i

145 lts provide further insight into the role of Rot in the regulatory cascade of S. aureus virulence gen

146 Noble rot-infected berries of cv Semillon, a white-skinned var

147 Rot infusion affected RLM little.

148 bind within the major groove, contributes to Rot interaction with target promoters.

149 says, we found that the repression of hla by rot is dependent on sae.

150 Our findings indicate that Rot is not only a repressor but a global regulator with

151 rough rotational diffusion and showed that D(rot) is an advantageous observable for monitoring bindin

152 Repressor of toxins (Rot) is known to be a global regulator of virulence gene

153 and discovered that the repressor of toxins (Rot) is part of this pathway.

154 unction of Rot, but not the transcription of rot, is regulated by the staphylococcal accessory gene r

155 characterization is shared among these brown rot lineages, despite their diverse genomes and secretom

156 sumed sizeable crustaceans that sheltered in rotting logs.

157 a 6- to 8-month period after cutting down a rotted maple tree (Acer sp.).

158 data implicated the importance of sae in the rot-mediated repression of hla in S. aureus.

159 However, the mechanism by which Rot mediates gene regulation has remained elusive.

160 timicrobial activity was tested against root-rot microorganisms, among others.

161 a dichotomy between the white-rot and brown-rot modes of wood decay.

162 of growth likely involves degradation of the rot mRNA but not the inhibition of rot transcription.

163 We propose that the RNAIII-rot mRNA interaction plays a key role in agr regulation

164 omplementary to two G-rich stem loops of the rot mRNA translation initiation region (TIR).

165 tary stem loops, followed by the cleavage of rot mRNA.

166 defining multiple B mating types in the wood-rotting mushroom Schizophyllum commune are predicted to

167 Finally, we tested the rot mutant in a mouse catheter model of biofilm infectio

168 creted protease genes were up-regulated in a rot mutant, and we hypothesized that this regulation cou

169 the cysteine proteases, were increased in a rot mutant.

170 sing multiple different assays, and we found rot mutants in other strain lineages were also biofilm d

171 We show that a rot mutation returns wild-type virulence to an agr mutan

172 Unlike bunch rot, noble rot promotes favorable changes in grape berri

173 ural function is to participate in the brown rot of wood and that it may enable brown-rot fungi to de

174 Fungi that cause brown rot of wood are essential biomass recyclers and also the

175 d most efficiently by fungi that cause white rot of wood.

176 ed by EPA in 1995 for control of postharvest rots of pome and citrus fruit, respectively, and are com

177 the vascular parenchyma, and maceration and rotting of the petiole and central bud.

178 The evaluation of Botrytis cinerea as noble rot on withered grapes is of great importance to predict

179 or brown rot, based on the ability (in white rot only) to degrade lignin along with cellulose and hem

180 ions due to extreme susceptibility to a root-rotting oomycete (Pythium spp), demonstrating that these

181 ve typically been classified as either white rot or brown rot, based on the ability (in white rot onl

182 s suggest that wet heartwoods, regardless of rot or not, occur widely in living trees on various habi

183 the soil, previously being leached out from rotting PA-plants.

184 tive response elicitor harpin (HrpN) of soft rot pathogen Erwinia chrysanthemi strains 3937 and EC16

185 -dependent manner by infection with the root-rot pathogen Pythium irregulare.

186 detailed the life history of the grape black rot pathogen.

187 even when immersed in inoculum from the root-rotting pathogen Nectria haematococca.

188 ion of ions and small molecules play in soft-rot pathogenicity.

189 Soft rot pathogens cause significant losses worldwide in frui

190 border cells of roots exposed to cotton root rot (Phymatotrichopsis omnivora), and the value of 7,4'-

191 ade with grapes infected and wilted by brown rot (Plasmopara viticola).

192 Rot plays a key role in regulating S. aureus virulence t

193 sition in S. lacrymans relative to the brown rot Postia placenta.

194 owed that turned green and also sprouting or rotting potato flesh contain high amounts of toxic solan

195 We show that insertion into the rot promoter by IS256 results in the derepression of cyt

196 ococcal lysates retarded the mobility of the rot promoter fragment and that the effect was reduced, b

197 nity purification of proteins binding to the rot promoter fragment, followed by N-terminal protein se

198 Primer extension analysis of the rot promoter revealed a number of discreet products.

199 Unlike bunch rot, noble rot promotes favorable changes in grape berries and the

200 dependent upon the presence of a functional Rot protein, and Rot was shown to be able to bind to the

201 dependent upon the presence of a functional Rot protein.

202 In Rot rat brain mitochondria (Rot-RBM) there was a 30-40%

203 -fold increase in O*2- or H2O2 generation in Rot-RBM oxidizing glutamate.

204 However, Rot-RBM required two times less Ca2+ to initiate permeab

205 In Rot rat brain mitochondria (Rot-RBM) there was a 30-40% inhibition of respiration in

206 oxygen species that increased 2-fold in the Rot-RBM.

207 The resulting energy of activation DeltaG()rot reflects the spatial requirement of the ortho substi

208 Transcriptional study has also shown that rot repressed sae, especially at the sae P3 promoter.

209 esults from the Agr system's inactivation of Rot repressor activity.

210 Rot (repressor of toxins), a SarA homologue, was previou

211 erived from backcrossing a Phytophthora root rot resistance locus from the donor parent Kingwa into t

212 Mutations in rot restore in vitro toxin production to agr-negative st

213 Noble rot results from exceptional infections of ripe grape (V

214 activities correlate with hla expression in rot, rot sae, and rot sae sarT mutants of COL.

215 otyviruses (Rsv1 and Rpv), Phytophthora root rot (Rps1, Rps2, and Rps3), and powdery mildew (rmd).

216 y mildew (Rmd-c), Phytophthora stem and root rot (Rps2), and an ineffective nodulation gene (Rj2) map

217 nt of rot and sae isogenic single mutants, a rot sae double mutant, and a rot sae sarT markerless tri

218 was not able to rescue the hla defect of the rot sae double mutant.

219 ngle mutants, a rot sae double mutant, and a rot sae sarT markerless triple mutant were constructed f

220 ate with hla expression in rot, rot sae, and rot sae sarT mutants of COL.

221 A rot sae sarT triple mutant was not able to rescue the hl

222 vities correlate with hla expression in rot, rot sae, and rot sae sarT mutants of COL.

223 rbon--and is derived from an ancestral white rot saprotrophy in which both lignin and cellulose are d

224 of both ectomycorrhizal biotrophy and brown rot saprotrophy were accompanied by reductions and losse

225 ntary RNAs would be predicted to occlude the rot Shine-Dalgarno (SD) site and to block rot translatio

226 ose, and they group close to the model white-rot species Phanerochaete chrysosporium in the PCA.

227 comycetes, which is reconstructed as a white rot species, and then contracted in parallel lineages le

228 ent and functional in both blackleg and soft rotting species of Erwinia.

229 to the SMF, no difference was noted between ROT spectra of unexposed and exposed yeast cells, which

230 We also compared the ROT spectrum and the extracted electrical characteristic

231 to dissect the genetics of Sclerotinia stem rot (SSR) [caused by Sclerotinia sclerotiorum (Lib.) de

232 leaf senescence, in turn, leads to charcoal rot, stalk lodging, and significant yield loss.

233 in the Polyporales, which harbors many white-rot taxa, whereas MnPs and VPs are more widespread and m

234 three additional regulators (SarA, SarZ, and Rot) that bind to the overlapping promoter region of abc

235 y, focusing first on fusarium root and crown rot, then including take-all and pythium and rhizoctonia

236 239) because of the activity associated with rot::Tn917 mutant strains.

237 ium support an evolutionary shift from white-rot to brown-rot during which the capacity for efficient

238 Thus S. aureus uses the transcription factor Rot to repress secreted protease levels in order to buil

239 Chronic infusion of rotenone (Rot) to Lewis rats reproduces many features of Parkinson

240 ta suggest that the primary mechanism of the Rot toxic effect on RBM consists in a significant increa

241 on of the rot mRNA but not the inhibition of rot transcription.

242 f these loops are critical for inhibition of rot translation and suggest that this inhibition is affe

243 ses, we show that RNAIII does, indeed, block rot translation.

244 he rot Shine-Dalgarno (SD) site and to block rot translation.

245 we demonstrate that the production of ROS by ROT treated AML12 hepatocyte cells dissociates the Trx-A

246 (CI) generated ROS, in response to rotenone (ROT) treatment, is based on the ability of reduced Trx t

247 nents, e.g. potential scaffolding cofactors (Rot/TROVE and SPFH/Band-7 modules) with their respective

248 unusual; the rotational transition state 9a-rot-ts connects directly to the orthogonal transition st

249 A more nuanced categorization of rot types is needed, based on an improved understanding

250 oteomic analysis of grapes infected by noble rot under withering conditions to identify possible mark

251 ground state decreased the expected DeltaG()rot values resulting in a minimization of their apparent

252 Rot was found to form a dimer, with each monomer harbori

253 he presence of a functional Rot protein, and Rot was shown to be able to bind to the seb promoter.

254 llin-resistant S. aureus strain deficient in Rot was unable to form a biofilm using multiple differen

255 scripts and protein production controlled by Rot, we observed that all the secreted protease genes we

256 rich loops of RNAIII and the G-rich loops of rot, we show that the sequences of these loops are criti

257 )Ir with species of the type ROAr, RO2CMe or ROTs, where R possesses beta-C-H bonds (e.g., R = ethyl

258 s of cattle such as liver abscesses and foot rot, which have economically important consequences for

259 ate recurring consumption of crustaceans and rotted wood by large Late Cretaceous dinosaurs.