ライフサイエンスコーパス: ruggedness

1 terms of assay sensitivity, selectivity, and ruggedness.

2 tal elevation model for a measure of terrain ruggedness.

3 e state, or could slow folding by increasing ruggedness.

4 verage values of Delta occur at intermediate ruggedness.

5 towards the native state is larger than its ruggedness.

6 the tortoise-hare pattern is an indicator of ruggedness.

7 etection capability, trueness, precision and ruggedness according to the Youden's approach.

8 y of fitness optima, which dominates at high ruggedness and acts to decrease Delta.

9 increase the fitness, which dominates at low ruggedness and acts to increase Delta; and (2) a higher

10 e landscape is difficult owing to both local ruggedness and amino acid-specific epistatic hotspots an

11 ories by multiple chemists authenticates the ruggedness and good reproducibility of the analytical pr

12 nges for theory and experiments owing to the ruggedness and high dimensionality of these potentials,

13 mplified design could improve robustness and ruggedness and may allow device construction via nontrad

14 basin) has the largest average depth-related ruggedness and slope, at all resolutions.

15 apeutic monoclonal antibodies, demonstrating ruggedness and suitability for high-throughput process a

16 the sensor to overcome technical problems of ruggedness and would therefore be ideal for industrial p

17 components in the GC system, thus improving ruggedness and, consequently, reducing need for frequent

18 are attractive because of their small size, ruggedness, and amenability to automated handling.

19 , the number of energy basins, the landscape ruggedness, and the slope decrease accordingly; ii), the

20 Analysis speed and system ruggedness are key requirements for bioanalysis of thous

21 ecreased mutational robustness and increased ruggedness, as measured by fitness effects of mutations

22 etween two cutoffs for 5% and 10% artificial ruggedness becomes negligible for potentials decreasing

23 oach has improved both assay sensitivity and ruggedness, compared to the whole plasma protein digesti

24 The artificial ruggedness decreases to tolerable thresholds for cutoffs

25 folding experiments of proteins and RNA, the ruggedness energy scale epsilon, can be directly measure

26 This artificial ruggedness exists for short cutoffs and gradually disapp

27 arity, sensitivity, accuracy, precision, and ruggedness, for both of these methods were comparable wi

28 plexes agree with the analysis of artificial ruggedness in a dataset of 62 protein-protein complexes,

29 lyte for improved specificity and analytical ruggedness in quantitative LC-MS-MS.

30 e predictions in simulated populations where ruggedness is manipulable, we explore average fitness in

31 Increasing the ruggedness leads to two competing effects: (1) more poss

32 ility (<21% over the maximum residue limit), ruggedness (<5.6%) and stability.

33 We provide a tool based on terrain ruggedness modelling of individual catchments to predict

34 hat demonstrate the potential usefulness and ruggedness of LTP-MS for the detection of explosives of

35 The interaction cutoff contribution to the ruggedness of protein-protein energy landscape is studie

36 However due to the size and ruggedness of RNA energy landscape, energy-guided search

37 These data demonstrate that severe ruggedness of RNA folding landscapes extends into confor

38 loop-receptor interaction in determining the ruggedness of the energy landscape for folding of the Te

39 in the loop contribute significantly to the ruggedness of the energy landscape.

40 on-native secondary structure determines the ruggedness of the energy landscape.

41 dispersion in fitness that characterizes the ruggedness of the evolutionary landscape.

42 multiple sequence changes, can modulate the ruggedness of the folding energy landscape.

43 zymes and provided a preliminary view of the ruggedness of the landscape, relating function to struct

44 vs the above parameters, we demonstrate the ruggedness of the method in predicting VD through the Oi

45 s controlled by solvent friction alone, with ruggedness of their energy landscapes having no conseque

46 To demonstrate the ruggedness of this approach, optimized cocktails were fi

47 The ruggedness of this interface was evident by the continuo

48 In the ruggedness test, sample amount, pre-extraction time, des

49 Through ruggedness tests, the application field of radiochemical

50 lifetimes and increases their robustness and ruggedness, thus making them more amenable for field app

51 chniques allow their unprecedented oxidative ruggedness to be monitored and verified.

52 Assay ruggedness was demonstrated by consistent internal stand

53 quate instrumental performance, some lack of ruggedness was encountered during routine application.

54 The assay ruggedness was improved by optimizing the trypsin digest

55 h %CV of 8.2-9.9 and 7.1-9.8%, respectively; ruggedness with %CV of 9.3-17.5%; spike recovery of 80-1

56 ee-energy surface that exhibits native-state ruggedness with apparently similar barrier heights to fo