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3 SI-2 meets all of the criteria of Lipinski's rule for a drug-like molecule and has a half-life of 1 h
4 learning rule, we present an online learning rule for a recurrent neural network that achieves near-m
6 a subset of bacterial OSTs follow their own rules for acceptor-site specificity, thereby expanding t
8 structure given the task of defining uniform rules for access to and distribution of health care, ben
9 To investigate more intensively the grammar rules for active regulatory sequence, we made libraries
10 An adaptive treatment strategy (ATS) is a rule for adapting a treatment plan to a patient's histor
11 h the circularly polarized optical selection rules for addressing individual valley excitons and trio
12 a variety of locations follow a generalized rule: for all nerve pathway origins, the soma cluster ce
13 In this review, five of the effective design rules for approaching LBG semiconducting polymers with h
16 4.1, Glt1, and Ca(2+) The data show that the rules for astrocyte engagement in a neuronal circuit are
17 a(2+)and glutamate indicators to explore the rules for astrocyte engagement in the corticostriatal ci
18 linear discriminant analysis, classification rules for authentic and paraffin adulterated beeswax sam
20 and February 2013 (when predefined stopping rules for benefit were met) and outcome evaluations cont
21 preted with an expanded version of Polanyi's Rules for bimolecular reactions, and three trends are ev
22 ne isomers that follow the isolated pentagon rule for C(82), the cage stability changes markedly betw
24 Consequently, progress in developing design rules for cancer nanomedicines has been slow, hindering
25 ed to derive three additional classification rules for case subjects and one for control subjects.
26 t, and recently on bacteria, have identified rules for cell size regulation in single cells, but in t
27 ISECT) to identify the heterogeneous binding rules for cell-type-specific TF occupancy and analyze th
29 In the validation population, the prediction rule for children younger than 2 years (normal mental st
31 erived and validated age-specific prediction rules for ciTBI (death from traumatic brain injury, neur
32 aining set generated a decision-making tree (rule) for classifying voxels as malignant or benign, whi
33 ead injury can now be guided by a prediction rule for clinically important traumatic brain injury.
34 during evolution, and Hebbian-like learning rules for clusters where neurons increase their synchron
35 n of the fishery ecosystem, and that the 10% rule for collapse should not be interpreted out of conte
37 the first steps toward developing synthetic rules for complex two-dimensional covalent organic chemi
43 nd this large amount of new information, new rules for crystal growth need to be developed and tested
44 bursting in a manner analogous to the timing rule for cue-reward learning paradigms in behaving anima
47 in version 1.2.1 or higher and the stopping rule for declaring a change early is available in versio
48 temperature programs and instituted a set of rules for defining the separation of OC and EC to quanti
49 rospective study was to develop a prediction rule for delirium in a cardiac surgery cohort and to val
51 s improved understanding, we propose several rules for designing experiments for minimizing off-targe
52 ifying new Env-host cell receptor pairs, the rules for designing optimal Env libraries are still uncl
55 as small as 60 nm and provide simple design rules for determining the conditions under which nanocha
56 ent sorts of input, forms of processing, and rules for determining the output are appropriate under d
60 ITDP may provide a general synaptic learning rule for distinct forms of hippocampal-dependent memory
61 t algorithm that properly addresses all SBGN rules for drawing PD maps, including placement of substr
65 rmore, instead of a few master combinatorial rules for each stress condition, many rules were discove
66 ings establish ganglionic eminence-dependent rules for early synaptic integration programs of distinc
69 ticular food web matrix properties as design rules for economically and biologically sustainable indu
70 vestigate single-guide RNA (sgRNA) targeting rules for effective transcriptional activation, to demon
72 ogether these properties define the temporal rules for efficient information transfer at DG-CA3 synap
75 an be understood in terms of the Wade-Mingos rules for electron counting, suggesting that it may be a
77 und, we have identified new materials design rules for emerging sodium-ion systems that do not apply
78 ndent plasticity (STDP), a synaptic learning rule for encoding learning and memory, relies on relativ
80 electronic-based discussion, following clear rules for establishing consensus and agreement/disagreem
81 electronic-based discussion, following clear rules for establishing consensus and agreement/disagreem
84 s confirmed that the mode symmetry selection rules for FCS are the same as for Raman scattering and t
87 atibilities in a rare exception to Haldane's rule for female sterility in field cricket sister specie
88 , derived from the histograms, traffic-light rules for frequently observed, rare, and highly unlikely
89 for inhibitory neurons, suggesting different rules for functional excitatory-inhibitory interactions
90 Finally, we observe that there are general rules for functional molecular motors across the differe
92 ials (n = 36 per group), additional stopping rules for futility lead to the saving of resources of up
95 ment specific enhancements, such as negation rules for general practitioners' entries and a regular e
99 DNA </= 2 x 10(5) IU/mL, the APASL stopping rule for HBeAg-negative CHB patients with proper off-the
100 The sensitivities of three clinical decision rules for head injuries in children were high when used
101 or the first time, one can establish general rules for heavy metal binding to Cys-rich sites in desig
102 DB), we have deciphered and rationalized new rules for helix-helix interfaces of a common protein-fol
108 urthermore, this approach may reveal general rules for how circuit structure and neural coding within
110 t guilds, suggesting that there may be basic rules for how sets of antagonists interact with resource
111 membrane proteins must be recovered, but the rules for how this multiple cargo selection is accomplis
112 Using these results, we postulated a folding rule for i-motif formation, analogous to (but different
113 guide future research by delineating several rules for identifying appropriate templates and molecula
115 dy was the first to establish classification rules for identifying CRS in school-aged children, using
117 igators to train and evaluate classification rules for identifying objects related to processes like
121 the system automatically generates low-level rules for independent climbing robots that guarantee pro
124 cuits with intrinsically active neurons have rules for information transfer and storage that distingu
125 ceptors to control the efficacy and temporal rules for information transfer at DG-CA3 connections.
130 the need for developing individual agronomic rules for iodine biofortification of carrot for: (a) con
132 I derive expanded versions of Hamilton's rule for kith and kind selection, generalizing Hamilton'
135 ly confined optical fields, the conventional rules for light-matter interactions need to be re-examin
138 provides a powerful heterosynaptic learning rule for long-term gating of information flow through th
139 agment library, the bioisostere library, the rules for metabolic stability, the toxicophore library,
143 ytically testing the accuracy of the product rule for more than five loci has hitherto remained an op
144 ed that long-term persistence (>1 y) was the rule for most dsDNA viruses observed, suggesting that bo
151 nominal mass), and eliminating the "nitrogen rule" for nominal mass determination of number of nitrog
156 tive explanatory power, the functions of and rules for organizing maps and their plasticity are not w
161 rophobic surface area; (iii) a well-defined "rule" for packing of stable cores exists, but this rule
163 ial databases, we sought to develop stopping rules for patients destined to fail boceprevir-based com
164 tudy was to determine quantitative injection rules for pediatric PET allowing clinical implementation
168 nder which underlying spike-timing-dependent rules for potentiation and depression can be separated f
169 can be prevented by precisely balancing STDP rules for potentiation and depression; however, experime
170 hat represents a novel methodology to define rules for predicting gene function by examining the emer
172 ts establishes the general utility of the RS rules for predicting retinocollicular topography, and de
173 reaction led to the development of powerful rules for predicting the regioselectivity of borylation,
175 stic acceptance of it to evaluate prediction rules for primary prevention of cardiovascular disease.
178 results provide important and useful design rules for QD-based light harvesting applications using t
179 el-to-fluid melting temperatures (T(m)), the rules for raft formation in membranes are not completely
180 vations and physical model establish general rules for raft partitioning of TMDs and support the cent
183 subtle material issues of control and design rules for reconfigurable dipolar materials with building
184 marking reveals distinctive factor-specific rules for recruitment of these crucial transcription fac
185 derived and validated a clinical prediction rule for recurrent CDI that is simple, reliable, and acc
186 This study aimed to develop a prediction rule for recurrent CDI using the above derivation cohort
188 gly, these results raise questions about the rules for renal filtration, given that these large molec
192 ate how to implement a sequential monitoring rule for safety using a completed phase I trial that inc
193 The system generates candidate names using rules for scientific names and applies probabilistic mac
194 vailability of electronic media and parental rules for sedentary behaviours was self-reported by chil
197 s transplanted bacterial enzyme, and provide rules for selecting Cas9 target sites distinct from and
198 iews, peer interviews, scores using an "and" rule for self- and peer reports, and separate tests for
200 extrinsic plasticity (DEP) as a new synaptic rule for self-learning systems and apply it to a number
203 formly distributed over its surface, and the rules for self-replication are encoded into the specific
204 derivative that does not obey the classical "rules" for shape and functional group placement that are
205 any have viewed microbes as following strict rules for shifting their metabolic activities when preva
206 Our observations allowed for deducing a rule for SLC6 family members: a hydrophobic residue (Tyr
208 re to nicotine during adolescence alters the rules for spike timing-dependent plasticity in prefronta
209 dividual release sites also revealed general rules for spontaneous and evoked release, and indicate t
210 ese findings, coupled with other established rules for SR proteins, provide a theoretical framework t
211 d Protection Agency (EPA) proposed a revised rule for "Standards of Performance for Greenhouse Gas Em
213 ve ability of the CHA(2)DS(2)VASc prediction rule for stroke and death in a nonanticoagulated populat
214 lometric method harnessing normative scaling rules for subcortical size and shape in humans, which we
216 on between SH3BP2 and Tankyrase and describe rules for substrate recognition by this poly(ADP-ribose)
224 urones in the inferior olive implement novel rules for synaptic integration and suggest new principle
225 are robustly expressed, suggesting different rules for synaptic plasticity across these regions.
226 c events in a wide temporal window, and that rules for synaptic plasticity in human neocortex are rev
230 emical and genetic analyses to delineate the rules for TAM receptor-ligand engagement and find that t
233 ing techniques (2) development of a decision rule for the constructed FLN to optimize functional anno
234 n the form of an activity-dependent learning rule for the development of retinocollicular projections
237 which provides a hitherto unexpected design rule for the incorporation of nanoparticles within cryst
238 interactions between networks play a crucial rule for the outcome of evolutionary games taking place
239 iously explained by an economical clustering rule for the probability of functional connectivity betw
241 This review seeks to set the basic ground rules for the analysis of different initiation pathways
242 the foundation toward defining the molecular rules for the ARO/CYC cyclization specificity, whose rat
248 AD co-oligomer and therefore to draw general rules for the design of PDI-based dyads and triads with
249 is essential for the development of general rules for the design of peptoids with discrete and novel
250 the mathematics of tessellations, we derive rules for the design of single CMPs that self-assemble i
251 ds have been condensed into a set of general rules for the design of thermostable CHA circuits with h
256 e segment, providing simple geometric design rules for the fabrication of complex 3D structures.
260 homoallylic system dissociated according to rules for the homoallylic system, with an additional fra
262 we analyze current data to distill a set of rules for the induction and maintenance of central memor
265 colleagues, has developed DSSs and decision rules for the management of diseases in a variety of cro
266 sualize the resulting networks, defining the rules for the molecular interactions typically requires
267 ved of these CTCF interactions have specific rules for the orientation of the paired CTCF sites, impl
273 of these experiments provide a set of ground rules for the successful engineering of hr-PKS and PKS-N
275 ent literature regarding clinical prediction rules for the use of cranial computed tomography (CT) in
276 rto overlooked dependence on (or 'propensity rule' for) the magnetic quantum number m of the molecule
280 are few organizational principles or guiding rules for this highly hysteretic, dissipative material.
281 ditis elegans, uncovering a conserved set of rules for this protein modification and identifying subs
282 e an important exception to temperature-size rules for three reasons: (i) we use many more species th
283 d Drug Administration (FDA) issued the final rule for title 21 of Code of Federal Regulations part 21
285 cal structural descriptors to derive general rules for trapping molecules in high-energy conformation
286 progressed, and use of a CVR-based decision rule for treatment in which patients with CVR impairment
291 a range of force-fields), we derived robust rules for urea unfolding that are valid at the proteome
294 cent study introduces a validated prediction rule for use in mild CHI, to limit the number of CT scan
295 ant next step would be to develop prediction rules for use in clinical practice, so that older person
297 and Drug Administration recently issued new rules for using ceftiofur in food animals in part becaus
300 lectric material, cannot be a general design rule for ZT enhancement and a detailed transport study i
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