ライフサイエンスコーパス: run length

1 in, plays an important role in governing the run length.

2 kinesin from the perspective of velocity and run length.

3 ommonly used to determine motor velocity and run length.

4 cluding stepping velocity and characteristic run length.

5 d slower than myoVa alone and with twice the run length.

6 distances large compared with the swimmers' run length.

7 t of Vamp2, a cargo of Kif1a, with decreased run length.

8 s motility, increasing both KHC velocity and run length.

9 ot all of which inhibit kinesin's processive run length.

10 op 2 increased actin affinity and processive run length.

11 ity of myosin V for actin and the processive run length.

12 charge on the neck coiled-coil decreases the run length.

13 rostatics, initial placement of solvent, and run lengths.

14 FPt, and mApple) cause aberrantly long motor run lengths.

15 track length has on observed characteristic run lengths.

16 Two of the 3 patients who died had very long run lengths (28.8 and 24.7 days, respectively), whereas

17 ng rate or motility parameters (velocity and run length) across experimental conditions.

18 ted published force-dependent velocities and run lengths, along with mechanical interactions between

19 y to associate motors appears to enhance the run length and attachment time of the quantum dot, impro

20 as no direct correlation between homopolymer run length and frameshift accumulation in the wild-type

21 in-1, -2, -3, -5, and -7 motors and measured run length and velocity in a single-molecule fluorescenc

22 iation from the microtubule, we measured Eg5 run lengths and also compared the duration of the last s

23 The analysis of run lengths and dwell times for the two-motor complex, w

24 activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously ch

25 antly bundled, and bundling enhances kinesin run lengths and provides a greater number of available k

26 ment of APP vesicles, increasing anterograde run lengths and reducing retrograde runs and segmental v

27 and -7 families engineered to have identical run lengths and surface attachments.

28 In addition, DCV run lengths and velocities were decreased in both axon c

29 merical simulations, the mean velocity, mean run length, and mean dwell time of the kinesin-1 motors

30 ctin for myoVa-HMM based on event frequency, run length, and speed.

31 increase in the number of motile particles, run length, and stimulated anterograde moving ZBP1 parti

32 ntrolled optical trap to probe the velocity, run length, and unbinding kinetics of mouse KIF3A/B unde

33 dence of the forward-to-backward step ratio, run length, and velocity.

34 sin Va by examining the velocity, processive run-length, and individual steps of a Qdot-labeled myosi

35 C loop L11 (KIF3ACDeltaL11) exhibited longer run lengths at approximately 1.55 mum than wild-type KIF

36 state, as well as the walking velocities and run lengths at various concentrations of ATP and ADP.

37 microtubules in 8-nm increments, with short run lengths averaging approximately eight steps.

38 e structural features that affect processive run length by analyzing the properties of chimeras of mo

39 Alteration of kinesin run length by MAPs represents a previously undiscovered

40 d some processive movements but with reduced run lengths compared with the other mutants.

41 Compared with run-length data, our model provides strong support for a

42 suggest that multiple myosin velocities and run lengths depend on both the compliance and the effect

43 he specific factors that determine kinesin's run length (distance traveled per microtubule encounter)

44 es the motors to generate a long tail in the run length distribution of the cell.

45 lymers vastly outnumber G and C HPs, and the run-length distributions of A and T homopolymers differ

46 On large datasets this compresses with run-length encoding by more than a factor of a hundred s

47 ces might determine the average velocity and run-length even when they are outnumbered by wild type m

48 om a sharp decrease in microtubule minus-end run length followed by a gradual decrease in plus-end ru

49 rest for the following high-order gray-level run-length (GLRL) gray-level zone size matrix (GLZSM) an

50 s large compared with the swimmers' size and run length has been an experimental challenge, as standa

51 lity of slippage is strongly correlated with run length, however, it was not clear whether shorter ru

52 Beyond regulating run length (i.e., biasing a random walk), the Drosophila

53 trate that Tau inhibits kinesin's processive run length in an isoform-dependent manner on GDP-microtu

54 However, the mean ECLS run length in survivors was 4.3 +/- 1.8 days and the lon

55 s a potent inhibitor of kinesin's processive run length in vitro suggests that it may actively partic

56 AD cells resulted in decreased mitochondrial run lengths in neurites.

57 These results imply that run length is determined not only by the load, but also

58 entional wisdom, the measured characteristic run length is directly coupled to the characteristic tra

59 Cargo run length is set by MT length, and higher MT coverage c

60 , V, randomness, r, stalling force, and mean run length, L, reveal a need for improved theoretical un

61 Particularly, well-designed incremental and run-length-limited encoding schemes are utilized to comp

62 vel histogram, gray-level co-occurrence, and run-length matrix statistics were evaluated.

63 on of the MT results in decreased processive run lengths measured using single-molecule fluorescence

64 The run length observed in vitro is compatible with long-dis

65 been reported to be responsible for shorter run lengths observed for another heterotrimeric kinesin-

66 .78 +/- 0.11 microm/s and display an average run length of 1.17 +/- 0.38 microm, which agrees well wi

67 ates at a moderate processivity, with a mean run length of 100-320 nt on ssDNA.

68 he plus end of microtubules, with an average run length of 2.6 +/- 0.2 mum, in a hand-over-hand fashi

69 This mechanism rivals the speed and run length of conventional motors, can support transport

70 is linearly correlated with the velocity and run length of dynein, and we use this linearity to predi

71 e level how calcium regulates the processive run length of full-length myosin V (dFull) and a truncat

72 Finally, the processive run length of kinesin is reduced on GMPCPP-microtubules

73 onformational transition, and the processive run length of myosin V, and thus, it is important to und

74 als disease-induced deficits in the flux and run length of retrogradely transported endosomes in both

75 We show that dynactin increases the run length of single dynein motors, but does not alter t

76 fect on motor activity, although the average run length of single kinesin molecules decreased by 30-5

77 ets as a function of sample size, processive run length of the motor, and distribution of track lengt

78 to account; 3) that the interaction time and run length of the motors can be estimated independent of

79 led-coil formation is highly processive with run lengths of approximately 1.23 mum and matching those

80 helix alpha7 is also highly processive with run lengths of approximately 1.62 mum and exceeding thos

81 ults in superprocessive motion, with average run lengths of approximately 10 mum, and that this prope

82 Single-motor run lengths of kinesin-2 were 4-fold shorter than those

83 Run lengths of mouse myosin V showed little salt depende

84 ns with kinesin-1 motors, the velocities and run lengths of peroxisomes driven by multiple myosinVa m

85 Processive run lengths of single molecules were determined by total

86 7A and produces a motor in which the average run length on actin at physiological concentrations of A

87 ssary to fit the dependences of velocity and run-length on substrate conditions.

88 h ionic strength there was not a decrease in run length or any selective inhibition of the diffusiona

89 C-terminal region of tubulin increased motor run length (processivity) by inhibiting "detachment" but

90 As in studies of multiple kinesins, the run lengths produced by two myosins are only slightly la

91 100 000-fold with increasing homonucleotide run length, representing the greatest effect on replicat

92 linker was replaced, kinesin-1 and kinesin-2 run lengths scaled identically with neck linker length,

93 he distinctive features of myosin VIIa (long run lengths, slow motility) will be very useful in video

94 esis at rates that increase as a function of run length, suggesting the involvement of misaligned int

95 -type KIF3AC and were more similar to KIF3AB run lengths, suggesting that L11 also contributes to tun

96 d rod of mouse myosin V (Y-MD) showed longer run lengths than mouse wild type at low salt.

97 ve kinesin mutants that have fourfold longer run lengths than the wild-type motor, but that have norm

98 r complexes on actin bundles, which showed a run length that was even shorter than that of a single m

99 With finite Markov chain Monte Carlo run lengths, the harmonic mean estimator may not be cons

100 neck-linker has been correlated with longer run lengths, the structural data to support this hypothe

101 t evolutionary pressures may limit kinesin's run length to optimize its in vivo function.

102 Best Overlap Graph) is robust to homopolymer run length uncertainty, high read coverage and heterogen

103 o microtubules was decreased threefold, bead run length was decreased over fourfold, and there was a

104 of KLC1 did not inhibit phagosome speed, but run length was decreased, and phagosome localization and

105 y 27% as compared to a single motor, whereas run length was increased by only 37%, much less than exp

106 lpha,omega-diene monomer with a 36 methylene run length was synthesized and polymerized, and the unsa

107 tage and lead to an increase in the expected run-length when the load on the cargo is in the vicinity

108 adding free P(i)) nearly doubled the kinesin run length, whereas reducing either the ATP binding rate

109 elevant quantities like average velocity and run-length without resorting to Monte Carlo simulations.