ライフサイエンスコーパス: saccular

1 Most RAAs were saccular (79%) and noncalcified (63%).

2 CT revealed 25 saccular (93%) and two fusiform (7%) aneurysms with a me

3 These results suggest that alteration in saccular afferent firing rates are sufficient to induce

4 tern of current spread involving only PC and saccular afferent neurons at this level of stimulation.

5 the vestibular nuclear complex suggest that saccular afferents contribute to the vestibulospinal sys

6 robiotin was injected iontophoretically into saccular afferents of toadfish (Opsanus tau) after intra

7 semicircular canal terminal fields, whereas saccular afferents projected to regions that received ve

8 Thresholds were similar for utricular and saccular afferents, as well as for lateral, fore/aft, an

9 ions, physiology, and best directions of the saccular afferents.

10 cheal fluid from preterm infants can prevent saccular airway branching.

11 in the fetal lung mesenchyme causes arrested saccular airway branching.

12 s chronic lung disease results from arrested saccular airway development and is most common in infant

13 Expression of Spry-4 during the saccular and alveolar stages, from E18.5 to postnatal da

14 iary bundles, that are presumed to represent saccular and lagenar maculae.

15 Only saccular and PC afferent neurons exhibited increases in

16 soura), a Stellifer-group sciaenid, both the saccular and utricular otoliths are enlarged relative to

17 Although there is extensive overlap of saccular and utricular projections, saccular inputs to t

18 ns, NT3 expression is weak and restricted to saccular and utricular supporting cells.

19 edominantly for fusiform aneurysm (n = 144), saccular aneurysm (n = 94), acute (n = 64) or chronic (n

20 lished the feasibility of an animal model of saccular aneurysm inflammation that can be seen with cli

21 Saccular aneurysm of left internal carotid artery was di

22 may be a cause of stroke; (2) it may mimic a saccular aneurysm on radiographic studies; and (3) it su

23 Saccular aneurysms (especially those with lobulated cont

24 Saccular aneurysms did not demonstrate a significantly h

25 Platinum coils placed into experimental saccular aneurysms in New Zealand White rabbits failed t

26 of whether to treat incidental intracranial saccular aneurysms is complicated by limitations in curr

27 Besides fusiform and saccular aneurysms that can thrombose, SA/C vasculitis l

28 er (mean age, 62.5 years; 68% women) who had saccular aneurysms that were 3 mm or more in the largest

29 Elastase-induced saccular aneurysms were created at the root of the right

30 onal animal care and use committee approval, saccular aneurysms were created in 20 rabbits and treate

31 Saccular aneurysms were created in New Zealand White rab

32 Elastase-induced, saccular aneurysms were created in rabbits and embolized

33 Angiography showed 13 saccular aneurysms with lobulated contour in 10 (77%).

34 ted at branch points of major vessels, large saccular aneurysms with multiple efferent arteries, doli

35 troying the wall into the adventitia causing saccular aneurysms, which can thrombose or rupture.

36 MR imaging showed three saccular aneurysms.

37 tilated lungs appeared immature, retaining a saccular architectural pattern.

38 th airway morphometry, elastin staining, and saccular branching similar to those in control littermat

39 abetes for 5 years resulted, as expected, in saccular capillary aneurysms, pericyte ghosts, acellular

40 By screening a bullfrog saccular cDNA library, we identified abundant PMCA1b and

41 g the glossopharyngeal nerve that enters the saccular chamber and in having the glossopharyngeal fora

42 hemical features and the localization of the saccular collagen (SC) protein in vivo using polyclonal

43 Conversely, the saccular cysts described by others arise predominantly b

44 SWOPP was diagnosed when a saccular dilatation of the terminal portion of the dorsa

45 t understanding of the active role played by saccular epithelium in the local regulation of the [Na(+

46 Most of the hair cells in the saccular epithelium in vitro were electrically tuned to

47 central (striolar)-zone afferents of the rat saccular epithelium.

48 Saccular fibers entered the medulla posterior to and at

49 addition, Cdh23 is expressed in the urticulo-saccular foramen,the ductus reuniens, and Reissner's mem

50 ckened interstitial mesenchyme and defective saccular formation.

51 Saccular geometry did not increase diameter-normalized s

52 , intraluminal thrombus, calcifications, and saccular geometry on peak wall stress (PWS) in finite el

53 in the number of small, potentially immature saccular hair bundles in reproductive females.

54 han the specific loss of Cx30 that underlies saccular hair cell death in Cx30(-/-) mice.

55 The seasonal increase in saccular hair cell density and smaller hair bundles in r

56 ty are concurrent with seasonal increases in saccular hair cell receptors.

57 CN1 was immunolocalized to discrete sites on saccular hair cell stereocilia, consistent with gradated

58 -Mb goldfish bipolar neuron and the bullfrog saccular hair cell.

59 leads to significant reduction of numbers of saccular hair cells and neuromasts and to hearing loss.

60 of voltage-gated Ca(2+) channels in bullfrog saccular hair cells by means of perforated and cell-atta

61 These results show that some frog saccular hair cells can generate spontaneous rhythmic ac

62 revealed on-going apoptosis specifically in saccular hair cells of Cx30(-/-) mice.

63 d this hypothesis at the afferent synapse of saccular hair cells of the leopard frog, Rana pipiens.

64 We conclude that frog saccular hair cells possess an intrinsic synaptic freque

65 ngle voltage-gated Ca2+ channels in bullfrog saccular hair cells to assess the roles of the channels

66 We used electron tomography of frog saccular hair cells to reconstruct presynaptic ultrastru

67 confocal and electron microscopy of bullfrog saccular hair cells using an anti-myosin-Ibeta antibody

68 xpressed in the mammalian organ of Corti and saccular hair cells was found to interact with an intrac

69 lectrophysiological recordings from bullfrog saccular hair cells with such spontaneously oscillating

70 As in frog saccular hair cells, adaptation shifted the current-defl

71 In saccular hair cells, TRPN1 was located prominently in th

72 y full-length HCN isoform expressed in trout saccular hair cells, was found by yeast two-hybrid proto

73 Using an in situ binding assay on saccular hair cells, we demonstrated previously that Myo

74 Using grassfrog (Rana pipiens) saccular hair cells, we show that the reported discrepan

75 of hair bundles and apical surfaces of frog saccular hair cells.

76 K(+) (K(Ca)) currents of frog (Rana pipiens) saccular hair cells.

77 f the ribbon-class afferent synapses in frog saccular hair cells.

78 some in the Cx30(-/-) background rescued the saccular hair cells.

79 Cx30 were not essential for the survival of saccular hair cells.

80 multimodal input early in development and on saccular input alone during the transition to amphibious

81 erlap of saccular and utricular projections, saccular inputs to the lateral portions of the vestibula

82 n contrast to the ubiquitous distribution of saccular inputs, those from the lagena are segregated to

83 minant polycystic kidney disease (ADPKD) and saccular intracranial aneurysms (ICA), the risk of MRA-d

84 Saccular intracranial aneurysms are balloon-like dilatio

85 romoted maturation with the development of a saccular lung.

86 ges, maintenance of otolith tethering to the saccular macula is dependent on tectorin alpha (tecta) f

87 amp recordings while the apical surface of a saccular macula was bathed with solutions containing var

88 the future superior crista, lateral crista, saccular macula, and posterior crista, as confirmed by i

89 canal ampullae, with weaker staining in the saccular macula.

90 the peristriolar zones of the utricular and saccular maculae.

91 striola is absent in both the utricular and saccular maculae.

92 s of homology to the zebrafish utricular and saccular maculae.

93 ulted in ablation of all hair cells from the saccular maculae.

94 cochlear sense organs, Reissner's membrane, saccular membrane, and the dark cells adjacent to canal

95 ew, cerebral aneurysms can be classified as 'saccular' - most commonly occurring, and 'other types',

96 The central projections of the utricular and saccular nerve in macaques were examined using transgang

97 The principal brainstem areas of saccular nerve termination were lateral, particularly th

98 lar apparatus, including degeneration of the saccular neuroepithelium and occasional malformation of

99 l complications rates; at least 10 patients; saccular, nondissecting UAs; original study published in

100 ne of the two distinct layers of the sunfish saccular OM.

101 lysate and in homogenates of microdissected saccular OMs.

102 Intracranial saccular or berry aneurysms are common, occurring in abo

103 Only saccular or broad-based aneurysms 2 mm or larger in grea

104 143 patients, 178 aneurysms) with unruptured saccular or fusiform aneurysms or recurrent aneurysms af

105 dextran amine was injected directly into the saccular or utricular neuroepithelium of fascicularis (M

106 e utricular otolith gradually fuses with the saccular otolith.

107 ously, we identified a cDNA from the sunfish saccular otolithic organ that encoded a new member of th

108 nd the utricles, deeply grooved sulci on the saccular otoliths, two-planar saccular sensory epithelia

109 nctions for Six1-Eya1-SHH pathway during the saccular phase of lung morphogenesis, providing a concep

110 opment as well as alveolarization during the saccular phase of lung morphogenesis.

111 Mutant lung histology at the saccular phase shows mesenchymal and saccular wall thick

112 and alveolar phenotype of mutant mice at the saccular phase.

113 the histologic alterations described in the saccular phenotype of Eya1(-/-) or Six1(-/-) lungs.

114 both Six1 and Eya1 genes results in a severe saccular phenotype, including defects of mesenchymal cel

115 atic increase in the magnitude of the evoked saccular potentials and a corresponding decrease in the

116 Saccular projections remain stable across larval develop

117 d sulci on the saccular otoliths, two-planar saccular sensory epithelia, and a unique orientation pat

118 lasm of supporting cells at the edges of the saccular sensory epithelium, indicating that these cells

119 of sensory hair cell ciliary bundles on the saccular sensory epithelium.

120 We monitored the synaptic output of saccular sensory receptors (hair cells) by measuring the

121 al NF-kappaB activation selectively impaired saccular stage lung development, with a phenotype compri

122 Fibulin-5 expression by saccular stage lung fibroblasts was consistently inhibit

123 -5 rescued extracellular elastin assembly by saccular stage lung fibroblasts.

124 Elastin organization was disrupted in saccular stage lungs of preterm infants exposed to syste

125 inhibited maturation of the lung during the saccular stage of development.

126 s of AMF differentiation appeared around the saccular stage of lung development (E18.5).

127 iation as well as alveolarization during the saccular stage of lung development are still unknown.

128 t were major bioprocesses induced during the saccular stage of lung development at E16.5-E17.5.

129 ngs exhibited lung morphology typical of the saccular stage of lung development, including dilated ai

130 d for transition from the canalicular to the saccular stage of lung development.

131 e pups at embryonic day 18, during the early saccular stage of pulmonary development.

132 ular stage but not during the canalicular or saccular stage surprisingly delayed distal differentiati

133 tical window for elastin assembly during the saccular stage that is disrupted by inflammatory signali

134 nontransgenic littermates was typical of the saccular stage.

135 ive inflammasome activity displayed abnormal saccular-stage lung morphogenesis and died soon after bi

136 of maximal fetal growth, and canalicular and saccular stages of fetal lung development).

137 The more rostral saccular striola is a curving band with hair cell orient

138 cretory protein (CC10+) airway-like and SPC+ saccular structures within 6 days.

139 stress and their lungs failed to form normal saccular structures.

140 Small saccular terminals contacted a few dendrites in the tang

141 In contrast, small saccular terminals contacted many dendrites and a few ne

142 natal hyperoxia acutely initially diminished saccular TGF-beta signaling coincident with alveolar sim

143 rtic aneurysms (n=10 total, 5 fusiform and 5 saccular) underwent 3-dimensional reconstruction with cu

144 Most auditory saccular units in reproductive, summer females showed ro

145 ans, including alveolar hypoplasia, variable saccular wall fibrosis, and minimal airway disease.

146 than 1,000 g: alveolar hypoplasia, variable saccular wall fibrosis, and minimal, if any, airway dise

147 at the saccular phase shows mesenchymal and saccular wall thickening, and abnormal proliferation of

148 geneity of pulse wave propagation within the saccular wall, which is lower in unstable aneurysms than

149 geneity of pulse wave propagation within the saccular wall.