ライフサイエンスコーパス: safe

1 ted by Solvent-Assisted Flavour Evaporation (SAFE).

2 model using live BCG and PPD is feasible and safe.

3 long-term anticoagulant treatment is likely safe.

4 PAD after neoadjuvant treatment is safe.

5 All interventions were safe.

6 nd their respective expertise such as PP was safe.

7 patients do not influence mortality and are safe.

8 isk surgical patients is either effective or safe.

9 reveal the workings of an evolutionary fail-safe, a duplicate enhancer mechanism that is hard-wired

10 Thus, it can serve as a promising safe adjuvant platform that can help to protect against

11 ators have been proposed to assess access to safe, affordable, timely surgical and anesthesia care, w

12 of mycotoxin levels currently recognized as safe (aflatoxin B(1): 2 mug/kg, ochratoxin A: 3 mug/kg,

13 demonstrated that SimCells can be used as a safe agent (as they cannot replicate) for bacterial ther

14 To date, no safe allergen-specific immunotherapy for patients with p

15 ns and pointing to phenytoin as a more human-safe alternative to dantrolene for therapies against hea

16 uvian population would consume the estimated safe amount of seafood.

17 n order to make the diagnostic procedures as safe and accurate, but also as cost-effective, as possib

18 normal development of a placental bed with a safe and adequate blood supply and a villous placenta-bl

19 Rifampin appears to be safe and as effective as isoniazid across many populatio

20 venous injection of (68)Ga-DOTA-Siglec-9 was safe and biodistribution was favorable for testing of th

21 : The tracer (18)F-JK-PSMA-7 was found to be safe and clinically useful.

22 ly weight-bearing in a functional brace as a safe and cost-effective alternative to plaster casting.

23 targeted vaccine administration in humans is safe and could be a viable option for the increasing bur

24 entional anti-tumor therapeutics, offering a safe and economic strategy for combination therapy.

25 design provides a platform technology for a safe and effective anti-PLA2 approach.

26 I placed without a scleral patch graft is as safe and effective as AADI placed with a patch graft in

27 s was that an acceptable cure need not be as safe and effective as optimally delivered antiretroviral

28 erative diagnosis is essential for providing safe and effective care during cancer surgery(1).

29 Safe and effective COVID-19 vaccines must avoid VAH.

30 and highlights ongoing research to optimise safe and effective delivery of vectors into the nervous

31 Identifying new drug targets and developing safe and effective drugs is both challenging and risky.

32 onclude that a 4-week diet low in FODMAPs is safe and effective for managing persistent gut symptoms

33 fovea-sparing yellow subthreshold laser was safe and effective for treating CI-DME patients with goo

34 fication and IOL implantation surgery can be safe and effective in eyes with uveitis.

35 The flexible ArtificialIris seems to be a safe and effective iris prosthesis in combination with a

36 increased community penetration supported a safe and effective LTx practice during the early COVID-1

37 and supports this type of laser therapy as a safe and effective minimally-invasive treatment option.

38 Mechanical neuro-thrombectomy seems equally safe and effective on a single or biplane angiography sy

39 F-DMEK is a safe and effective procedure in failed PK patients, with

40 Probing is a safe and effective procedure.

41 These results have implications for the safe and effective production of not just current produc

42 limination will require widespread access to safe and effective radical cure.

43 En-bloc HLTx technique is a safe and effective strategy, decreasing operative times,

44 harmaceutical therapy (RPT) is emerging as a safe and effective targeted approach to treating many ty

45 er both gain and loss of function to develop safe and effective therapeutic strategies.

46 Early mobilization is considered a safe and effective therapeutic strategy for accelerating

47 ght to the clinic and hopefully will provide safe and effective therapies.

48 Pericardiectomy is a safe and effective treatment for posttransplant constric

49 ografts, and may be a novel approach for the safe and effective treatment of breast cancer.

50 Tocilizumab might therefore be another safe and effective treatment to prevent relapses in pati

51 One challenge is identifying a safe and effective tumor antigen.

52 nd, when instituted, are expected to promote safe and effective use.

53 A safe and effective vaccine for severe acute respiratory

54 A safe and effective vaccine is desperately needed to prev

55 use and open a new developmental path for a safe and effective vaccine.

56 ID-19 pandemic underscores the urgency for a safe and effective vaccine.

57 A substantial unmet need remains for safe and effective vaccines against dengue virus disease

58 There is a desperate need for safe and effective vaccines, therapies, and diagnostics

59 the treatment of myopia and astigmatism was safe and effective, and the reported AEs had no signific

60 Oral cholera vaccine (OCV) is safe and effective, but has not been seen as a primary t

61 While we found oral eplerenone to be safe and effective, further studies would be required be

62 h GDD implantation in children is relatively safe and effective, these data should be interpreted in

63 na was recommended and whether marijuana was safe and effective.

64 tracorporeal membrane oxygenation [ECMO]) is safe and effective.

65 riffithsin (GRFT), has been shown to be both safe and efficacious against HSV-2 and HIV-1 infections

66 ventricular septal defect (VSD) closure is a safe and efficacious alternative to surgery.

67 est available option in the race to identify safe and efficacious drugs that can be used to prevent a

68 logy, pharmacology, and medicine to discover safe and efficacious drugs.

69 ed virus (AAV) vectors have been shown to be safe and efficacious in clinical trials for diseases aff

70 ogical investigations for the development of safe and efficient biological control programs.

71 Materials capable of the safe and efficient capture or degradation of toxic chemi

72 This study point to soft bread as a safe and efficient source of melanoidins, that could be

73 PE, the pregnancy-adapted YEARS algorithm is safe and efficient, rendering computed tomographic pulmo

74 strointestinal cancer.RESULTSThe vaccine was safe and elicited mutation-specific T cell responses aga

75 amOVA EPIT via laser-generated micropores is safe and equally effective compared to SCIT with alum, w

76 ing extracorporeal carbon dioxide removal is safe and feasible and avoids the deleterious effects of

77 using an infusion time of less than 5 min is safe and feasible in clinical practice.

78 Conclusion: FME using EMI-137 appeared to be safe and feasible within a 1- to 3-h dose-to-imaging int

79 and mobilization during critical illness are safe and feasible, but little is known about the prevale

80 acement using 29-mm Sapien-3 and 34-mm ER is safe and feasible.

81 CRISPR-Cas9 gene-edited T cells is generally safe and feasible.

82 attack rates compared with placebo and were safe and generally well tolerated.

83 The vaccine was safe and generated robust immune responses, but delayed

84 Conclusion: (89)Zr-IAB22M2C imaging is safe and has favorable kinetics for early imaging.

85 s, considering the growing market demand for safe and healthy food products.

86 onclude that sofosbuvir-based DAA therapy is safe and highly effective in HCV-HIV patients with decom

87 ine ([fIPV] one fifth of normal IPV dose) is safe and immunogenic; however, id administration is perc

88 gents and the potential of IONPs to serve as safe and improved alternative to gadolinium-based chelat

89 Vaccination was found to be safe and induced a broad, strong, durable and functional

90 We sought to identify doses of RMD that were safe and induced HIV-1 expression.

91 CVac-primaquine/chloroquine is safe and induces sterile immunity to P. falciparum in so

92 vailability is high, AWL could be used for a safe and long-term storage of CO(2).

93 A safe and manufacturable mimic of anabolic bone is the pr

94 upon seven topics: 1) early mobilization is safe and may reduce healthcare costs, 2) safety criteria

95 tivity in and near the hospital bed, appears safe and mostly feasible in ICU patients requiring conti

96 y learned the probabilities of options being safe and of partners being reliable and combined these c

97 t selective intra-arterial embolization is a safe and painless procedure that is well tolerated becau

98 econd laser -assisted cataract surgery was a safe and precise procedure but enhanced visual outcomes

99 Conclusion: First-line SIRT is safe and produced promising outcomes in patients with uv

100 in of JUNV, has been demonstrated to be both safe and protective against AHF.

101 pine at the dose studied was confirmed to be safe and provides therapeutic exposure concentrations.

102 re, treatment with ferric carboxymaltose was safe and reduced the risk of heart failure hospitalisati

103 -low volume of iodine contrast seems to be a safe and reliable diagnostic tool to detect and assess T

104 deS treatment before AAV vector infusion was safe and resulted in enhanced liver transduction, even i

105 f NAMPT inhibitor at the tumor site offers a safe and robust means to alter an immune tumor microenvi

106 ology and genetic editing technique offers a safe and robust strategy in activating the body's immune

107 ferase immunoprecipitation system assay is a safe and sensitive method for detecting SARS-CoV-2 antib

108 Evolocumab was safe and significantly reduced lipid levels in dyslipide

109 and sizing of nanoparticles to ensure their safe and sustainable employment.

110 Aluminium batteries constitute a safe and sustainable high-energy-density electrochemical

111 of body fluids, the presented approach is a safe and sustainable route to meet the power requirement

112 s and patient group direction users provided safe and therapeutically appropriate medication.

113 th recurrent or advanced cervical cancer was safe and treatment-related adverse events were manageabl

114 coholic formulations of 4%-5% CHG seem to be safe and twice as effective as PVI (alcoholic or aqueous

115 KAF156 was safe and well tolerated and demonstrated high levels of

116 e further showed that a variant of AL002c is safe and well tolerated in a first-in-human phase I clin

117 the preventive treatment of migraine and was safe and well tolerated in patients for whom multiple pr

118 EZ width in any cohort.CONCLUSIONOral NAC is safe and well tolerated in patients with moderately adva

119 taneous VRC01 as single or multiple doses is safe and well tolerated in very young infants and is sui

120 Subcutaneous VRC01 was safe and well tolerated with only mild-to-moderate local

121 All doses were generally safe and well tolerated, with no clinically relevant cha

122 Flurpiridaz PET was safe and well tolerated.

123 Vaccines were generally safe and well tolerated.

124 anib and pirfenidone, the medical need for a safe and well-tolerated antifibrotic treatment of IPF re

125 timicrobial therapy (OPAT) is a widely used, safe, and cost-effective treatment.

126 safety profile of PFA potentiated efficient, safe, and durable PVI and LAPW ablation.

127 ign of a subunit-based vaccine that would be safe, and effectively protect against heterologous infec

128 We show that APP-103 is safe, and that it effectively promotes kidney function f

129 patients with SRI appeared to be relatively safe, and the potential benefit outweighed the theoretic

130 are needed that are effective, rapid acting, safe, and tolerable.

131 ylcellulose capsules are employed as a fast, safe, and user-friendly chemical delivery system contain

132 n is one of the necessary conditions for the safe application of 2D materials.

133 Lacosamide was efficacious and generally safe as adjunctive treatment for uncontrolled PGTCS in p

134 r in terms of local cancer control and is as safe as an international standard 15-fraction regimen af

135 Thoracoscopy is as safe as thoracotomy regarding leakage (OR -1.92; 95% CI

136 support system (AI-DSS) is as effective and safe as those guided by physicians in controlling glucos

137 ed for renal dysfunction appear feasible and safe assessing thromboembolic disease in critically ill

138 The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomo

139 y as the range of pressure for efficient and safe BBB opening is very narrow.

140 obubble destabilization occurred resulted in safe BBB openings, as shown by MR images and gross patho

141 e many individuals are still not offered the safe, best-evidence treatments recommended for OA care.

142 Additionally, such control would provide safe biocontainment of transgenes and gene drives.

143 Risk-averse behaviours, such as standing on 'safe' blocks and testing blocks prior to movement, incre

144 year of biweekly infusion of belapectin was safe but not associated with significant reduction in HV

145 Protein vaccines are safe, but conventional approaches for protein-based vacc

146 n that includes enfuvirtide post-alloBMT was safe, but life-threatening viral rebound can occur with

147 gister data strengthening and a modified WHO Safe Childbirth Checklist; facilities in the interventio

148 ts or an unpredictable-threat condition to a safe condition in healthy participants.

149 However, updating in a similar safe context erroneously shifts fear from the dangerous

150 eously shifts fear from the dangerous to the safe context.

151 The LNG-IUS appears to be a safe contraceptive with regard to HIV disease and may be

152 PBMT can be potentially a safe, convenient, and cost-effective modality to improve

153 Controllable, precise, and safe delivery of diagnostic biosensing devices and thera

154 ess to high-quality cancer care; (2) support safe delivery of high-quality cancer care; (3) advance p

155 For efficient and safe delivery to cancer cells, nucleic acids must genera

156 ncome countries must be understood to ensure safe deployment of these interventions in less affluent

157 There are further concerns regarding the safe disposal of fluoropolymers and their associated pro

158 use, waste collection, and recycling; expand safe disposal systems; and accelerate innovation in the

159 delivery system, selection of effective and safe dosage is the key to sparing local therapy.

160 ion with the histological analysis reveals a safe dose of microcapsules (20 x 10(6)), which has not l

161 ity water system that is regulated under the Safe Drinking Water Act.

162 Lack of access to safe drinking water is a global problem, and methods to

163 Access to clean and safe drinking water is a perpetual concern in Arctic com

164 d its potential to displace other sources of safe drinking water, which could in turn hamper efforts

165 (e.g., energy conservation, healthy living, safe driving).

166 As a guide to safe drug development, it therefore becomes important to

167 Ziv-aflibercept is a highly effective and safe drug in cases of active myopic CNV; however, a larg

168 is an urgent need for novel, affordable, and safe drugs for prevention and treatment of malaria.

169 h hydroxychloroquine is generally considered safe during pregnancy based on studies in patients with

170 , the exposure of released TLZ from a single safe, effective dose of the prodrug exceeded that of ora

171 SSIS is a safe, effective, and durable strictureplasty in patients

172 ing frontline clinicians' ability to deliver safe, efficient, and effective care.

173 al pathways should be established to provide safe elective cancer surgery during current and before f

174 been that alternative nitrogenases are fail-safe enzymes that are used in situations where molybdenu

175 The American Heart Association supports safe, equitable active transportation policies in commun

176 in collaboration with public health, enables safe evaluation and specimen collection outside the heal

177 This information may inform safe exercise and recovery protocols in asymptomatic mal

178 S (quick, easy, cheap, effective, rugged and safe) extraction step, and a liquid chromatography-ultra

179 e hospital 2 days after kidney transplant is safe, feasible, and improves value.

180 n areas have access to clean drinking water, safe food supply, and uncontaminated water bodies is ess

181 and/or refractory ITP during pregnancy seems safe for both mother and neonate and is likely to be hel

182 hese 10 nonpharmacological interventions are safe for cancer-related cognitive impairment management.

183 tshade leaves were evaluated and found to be safe for consumption.

184 tic exercise (ID) programs are effective and safe for hemodialysis (HD) patients to avoid functional

185 lations, this approach has been argued to be safe for post hoc tailoring of analysis windows under ma

186 It also appears to be safe for proceduralists to perform in this timeframe.

187 with addiction treatment may be feasible and safe for PWID with serious infections.

188 ompromise graft function and outcomes and is safe for the donor.

189 Additionally, the Pt NPs are safe for use in humans and can act as anti-cancer agents

190 etry estimates suggest that (64)Cu-Macrin is safe for use in humans.

191 ms at any time vs. blocks in which they were safe from screams.

192 The proposed preparation method ensures safe handling of the tissue sections guarantees the pres

193 zebrafish loci and efficient integration at safe harbor loci in porcine and human cells.

194 apeutic drugs to the brain, which provides a safe haven for cancer cells in the brain and confers poo

195 egligible, meticulous rules (precise triage, safe hospital path, high level of protection for health-

196 Programs promoting safe IDU practices, drug treatment, and hepatitis A and

197 Conclusion: (64)Cu-DOTATATE PET/CT is a safe imaging technique that provides high-quality and ac

198 Retinal fundus photography is a safe imaging technique used for capturing the overall st

199 tion schedule of PCV13 followed by PPSV23 is safe, immunogenic, and thus beneficial in the majority o

200 is, therefore, necessary in order to ensure safe implantation and positioning of the catheter in tho

201 orozoites [SPZ]) has been well tolerated and safe in >1526 malaria-naive and experienced 6-month to 6

202 Although it is generally safe in a clinical setting, it can be addictive, and sev

203 Moreover, it is found to be safe in animals with a dose of 30 mg/kg BID for 12 days

204 t that transfusion of convalescent plasma is safe in hospitalized patients with COVID-19.TRIAL REGIST

205 7), an oral NLRP3-specific inhibitor that is safe in humans.

206 lobinopathies, deferiprone was effective and safe in inducing control of iron overload during 12 mont

207 NSAIDs in the early postoperative period is safe in selected patients following major gastrointestin

208 CLC with PD-L1 expression at least 1% and is safe in selected patients with untreated brain metastase

209 that the hybrid approach may be feasible and safe in selected recipients.

210 3 weeks for local tumour control, and is as safe in terms of normal tissue effects up to 5 years for

211 We investigated whether eGFR only is safe in this setting.

212 flammatory disorders might be beneficial and safe, in particular to treat diseases of the vascular sy

213 sly assumed and is expected to be a good and safe intervention for controlling a mumps outbreak.

214 guided discontinuation of DAPT appears to be safe, irrespective of HBR.

215 Given that there are no safe levels of metals in infants, the observed increases

216 Li metal toward high-energy, long-life, and safe Li metal batteries.

217 - 1.1 hours/day kept B(T) and B(T) /A within safe limits throughout childhood, but B(T) increased 0.4

218 A safe low-cost alternative is provided by using broadly n

219 -generation lithium-metal batteries, a "fail safe" mechanism for internal short is highly desirable.

220 Injection of non-safe microcapsule dose leads to carriers staying in glom

221 The development of effective and safe nanobead-based interventions can be particularly re

222 ressive malignancies, and allowed apparently safe nonoperative surveillance for >80% of MT-negative p

223 ature, there is a need to achieve efficient, safe, nontoxic, fast, and economical processing of clini

224 -wide association study data, while ensuring safe open access to prevent research participant identif

225 t contribute to improving food security in a safe operating space, which is shrinking as a result of

226 ion to ensure that humanity remains within a safe operating space.

227 ir formations is essential for effective and safe operations.

228 offers a case-based discussion for reviewing safe opioid prescribing practices in the hematology sett

229 ts made repeated choices between harmful and safe options, each with different probabilities of gener

230 e initial viral infection is limited, and no safe or effective vaccine currently exists.

231 smaller hospital, and being in a state with safe patient handling and mobility legislation.

232 Safe patient handling legislation has been enacted in 11

233 cteristics after the passage of California's safe patient handling legislation.

234 ospitals reported slightly better scores for safe patient handling program variables than their count

235 -teaching hospitals for both hospital-level (safe patient handling programs and organizational practi

236 This study was to investigate the changes in safe patient handling programs in hospitals, and nurses'

237 However, greater positive changes in safe patient handling programs shown in certain hospital

238 For one of the cognitive strategies (safe place), the performance of pain attenuation was exp

239 tice guides are available to help facilitate safe prescribing.

240 m the cTnI mutation Gly203Ser, and present a safe, preventative therapy for associated cardiomyopathy

241 L-LLS is a safe procedure that can be standardized and successfully

242 To create a truly safe, productive, and vibrant environment in academia re

243 health problems through an agreed-on set of safe, quality, and cost-effective interventions at the i

244 setting of acute ischemic stroke in rats is safe, reduces infarct size and improves functional recov

245 oncentration of SBA must be controlled under safe regulations to avoid damaging human health.

246 Safe, reliable, and equitable water access is critical t

247 t of interventions, thereby facilitating the safe reopening of schools.

248 Mean safe-reporting scores were lower in the US than other En

249 s limited by difficulty in breathing, and no safe reusability), which have yet to be addressed in a s

250 ucture such as Complete Streets policies and Safe Routes to School initiatives, and the microscale of

251 demand motivates the pursuit of inexpensive, safe, scalable, and high-performance rechargeable batter

252 entration estimates are assumed to be on the safe side for comparison with environmental quality stan

253 hNVs are safe, stable, drug loadable, and suitable for genetic ed

254 ransformable nanovaccine offers a robust and safe strategy for cancer immunotherapy.

255 g materials and technologies could provide a safe strategy for geoengineering to mitigate global clim

256 TaNT clearly provides a safe strategy for large-scale ivermectin treatment and o

257 echanism of transformation results in a fail-safe strategy for the population as half of the populati

258 ly mild lesions with large plaque burden was safe, substantially enlarged the follow-up MLA, and was

259 Instead, it may represent a fail-safe system in case of impaired hypoglycemia sensing by

260 the treatment of BPH proved an effective and safe technique in patients who were not candidates for s

261 on predesigned conditions, without exceeding safe temperature limits that do not result in damage of

262 development of oncolytic VSV recombinants as safe therapeutics for cancer.

263 for an alternative, yet highly efficient and safe therapy.

264 esophageal dilation appears to be relatively safe, there is no evidence that it reduces esophageal eo

265 ified eplet mismatches was linear, without a safe threshold at which de novo DSA did not occur.

266 hibitor FXII900 is a promising candidate for safe thromboprotection in acute medical conditions.

267 metals) analyses proven that refined PPMO is safe to be consumed.

268 tantially mislead policymakers on when it is safe to remove travel bans or relax quarantine and socia

269 pediatric brain tumors and that metformin is safe to use and tolerable in this population.

270 noculation (DVI) with PfSPZ vaccine has been safe, tolerable, and feasible in adults, but safety data

271 ional and transplant center levels to ensure safe transplantation despite significant redirection of

272 00 IR sublingual HDM tablet is an effective, safe treatment for HDM-induced allergic rhinitis.

273 s immunotherapy (EPIT) may be a relevant and safe treatment for peanut allergy and may improve the qu

274 Allergen immunotherapy is a proven, safe treatment for respiratory allergies.

275 al prodrug design for the most effective and safe treatment of inflammatory arthritis.

276 The effective and safe treatment of pain is an unmet health-care need.

277 M techniques as an alternative effective and safe treatment option.

278 Allergen Immunotherapy is an effective and safe treatment, that modifies the natural course of alle

279 distinguish between potentially harmful and safe ultrasound conditions in the brain with very short

280 and Japan, S6821 and S7958 were approved as safe under conditions of intended use as bitter taste bl

281 ood and Drug Administration (FDA), to secure safe use of deep learning methods.

282 drug monitoring of NOACs and may improve the safe use of these drugs.

283 ated with COVID-19, developing effective and safe vaccines is a top research priority.

284 y data suggests that to design a potentially safe vector-based pan-Leishmania vaccine, without geogra

285 A safe waiting period of 17-18 d after final insecticide a

286 (quick, easy, cheap, efficient, rugged, and safe) was revisited and modified using mixed-mode SPE pu

287 other LMICs toward universal and affordable safe water access.

288 trition, overcrowding, and lack of access to safe water and healthcare can increase susceptibility to

289 nths reared specimens), the maximum possible safe weekly consumption (400 g) is suggested.

290 mtricitabine, and tenofovir alafenamide as a safe, well tolerated, and durable treatment for people w

291 Novel OPV2 candidates were as safe, well tolerated, and immunogenic as monovalent OPV2

292 he tetravalent vaccine regimen was generally safe, well-tolerated, and found to elicit higher immune

293 pally designed to keep the body biologically safe, which they do by continually monitoring and respon

294 asures are required to keep laboratory staff safe while producing reliable test results.

295 owever, the risk is modest and FHT is likely safe with regard to noninfectious uveitis risk in the ma

296 compartments of the lower leg appears to be safe with regard to the results of this study.

297 Conclusion Gadoxetic acid may be safe with respect to nephrogenic systemic fibrosis in th

298 2 patients demonstrated that the regimen was safe, with no treatment-related serious adverse events o

299 arily linked to more improvements in nurses' safe work practices and experiences of musculoskeletal s

300 pment of DHA-based nanoARVs as an effective, safe yet technically simple strategy to enhance brain de