ライフサイエンスコーパス: salen

1 ld asymmetrically substituted 2-quinoxalinol salens.

2 Nonsymmetric substitution of salen (1(R(1),R(2))) and reduced salen (2(R(1),R(2))) Cu

3 involving an equilibrium between nickel(II) salen (15) and two reduced forms, one being the metal-ce

4 titution of salen (1(R(1),R(2))) and reduced salen (2(R(1),R(2))) Cu(II)-phenoxyl complexes with a co

5 f the bimetallic aluminum(salen) complex [Al(salen)](2)O and tetrabutylammonium bromide (or tributyla

6 which the apical Ni site of the Ni*Cs-BINOL-salen activates the enone and the naphthoxide base activ

7 Chiral (salen)Al complex 1a catalyzes the highly enantioselectiv

8 A salen-Al-catalyzed aldol reaction was employed to constr

9 ylaluminum bromide was used to prepare three Salen aluminum bromide compounds salen((t)Bu)AlBr (1) (s

10 Optimization of a (salen)aluminum complex revealed significant remote elect

11 in catalytic applications compared with the salen analogues.

12 ernary complexes of Co(III)(salen)+, Fe(III)(salen)+, and Mn(III)(salen)+ with several angiotensin pe

13 n (EHC) reactions using catalytic nickel(II) salen as a mediator.

14 sion between helical diastereomers of nickel-salen-based foldamers can be observed on a NMR time scal

15 heir uranyl complexes combine a chiral (R,R) salen bridge and an inherent chiral tris-bridged quinoxa

16 '- bis(salicylidene)ethylenediamine iron (Fe(Salen)), but not other metal salen derivatives, intrinsi

17 Specifically, the dimeric yttrium salen catalyst accelerates the ring opening of aliphatic

18 ation of celestolide with a chiral manganese salen catalyst afforded the azide product in 70% ee, rep

19 ation of celestolide with a chiral manganese salen catalyst followed by trapping with aniline afforde

20 h CO2 using a bifunctional rac-/(S,S)-cobalt salen catalyst in high carbonate linkage selectivity (>9

21 A crystal structure of a Co-salen catalyst with two equivalents of benzaldehyde prov

22 e reaction is first order in the Ni*Cs-BINOL-salen catalyst.

23 available manganese porphyrin and manganese salen catalysts and various fluoride ion reagents, inclu

24 uctures show that this new class of Ni-BINOL-salen catalysts contains an unoccupied apical site for p

25 the design and development of chiral Co(III)-salen catalysts for enantioselective Diels-Alder reactio

26 In addition, chromium salen catalysts have been discovered as uniquely effecti

27 expressed in the design and synthesis of new salen catalysts whose effectiveness has been compared wi

28 ane-1,2-diamine-a common component of chiral salen catalysts-is a surprisingly weak director of absol

29 toward highly active and selective supported salen catalysts.

30 s with excess propylene oxide using aluminum salen catalysts.

31 4-EB) and CO2 using bifunctional cobalt(III) salen catalysts.

32 pproach toward polymer-supported, metalated, salen catalysts.

33 ary degradation studies using enantiopure Co(salen) catalysts are also reported.

34 g alkyn-1-yl radicals arising from nickel(I) salen catalyzed cleavage of the carbon-halogen bond of e

35 ble for elucidating the mechanism of Mn(III) salen catalyzed reactions and ultimately for designing o

36 rigin of asymmetric induction in the Mn(III)(salen)-catalyzed epoxidation by peracetic acid have been

37 tudy the Mn salen complex during the Mn(III) salen-catalyzed epoxidation of cis-beta-methylstyrene.

38 dinuclear clusters formed during the Mn(III) salen-catalyzed epoxidation reaction.

39 A pair of diastereomeric salen cavitands and their uranyl complexes combine a chi

40 ne oxide (PO) using biaryl-linked bimetallic salen Co catalysts was investigated experimentally and t

41 R) of terminal epoxides catalyzed by chiral (salen)Co(III) complex 1 x OAc affords both recovered unr

42 ution of terminal bis-epoxides catalyzed by (salen)Co(III) complexes affords epoxy-diols and N-protec

43 that the stereochemistry of each of the two (salen)Co(III) complexes in the rate-determining transiti

44 e absolute stereochemistry of each of these (salen)Co(III) complexes is the same.

45 g of oxetanes with alcohols is catalyzed by (salen)Co(III) complexes.

46 carbon dioxide with indene oxide utilizing (salen)Co(III)-2,4-dinitrophenoxide in the presence of an

47 In the (salen)Co(III)-catalyzed hydrolytic kinetic resolution (H

48 The (salen)Co(III)-catalyzed hydrolytic kinetic resolution (H

49 The commonly used (salen)Co-OAc and (salen)Co-Cl precatalysts undergo complete and irreversib

50 The commonly used (salen)Co-OAc and (salen)Co-Cl precatalysts undergo compl

51 antitative formation of weakly Lewis acidic (salen)Co-OH and severely diminished reaction rates in th

52 lled by partitioning between a nucleophilic (salen)Co-OH catalyst and a Lewis acidic (salen)Co-X cata

53 In contrast, (salen)Co-OTs maintains high reactivity over the entire c

54 to epoxide is reversible in the case of the (salen)Co-OTs.

55 ic (salen)Co-OH catalyst and a Lewis acidic (salen)Co-X catalyst.

56 ion of catalyst partitioning with different (salen)Co-X precatalysts and demonstrate that counterion

57 these targets with [(18)F]KF, labeling with (salen)CoF is possible in the last step and under excepti

58 transition metal fluoride catalyst, [(18)F](salen)CoF, and its use for late-stage enantioselective a

59 st catalyst system, which is prepared from a salen complex and an onium salt, this convenient route e

60 es in the modes of binding between the metal-salen complex and the peptide ligand.

61 Using a Cu(II) 2-quinoxalinol salen complex as the catalyst and tert-butyl hydroperoxi

62 A chiral iron(III)-salen complex based on a cis-2,5-diaminobicyclo[2.2.2]oc

63 , we have used dual-mode EPR to study the Mn salen complex during the Mn(III) salen-catalyzed epoxida

64 The aluminum salen complex exhibits exceptional selectivity for copol

65 present the first instances wherein a nickel salen complex has been used in this manner.

66 Coordination of cis-stilbene sulfide to the salen complex in a ligand substitution reaction was esta

67 For a nickel salen complex made from a particularly bulky ligand, pre

68 evaluate the proposed mechanism of a yttrium-salen complex-catalyzed acylation of secondary alcohols

69 ety of epoxides catalyzed by a chromium(III) salen complex.

70 The combined use of the bimetallic aluminum(salen) complex [Al(salen)](2)O and tetrabutylammonium br

71 ed salen ligand and the corresponding Co(II)(salen) complex at low monomer concentrations results in

72 synthesis using the same bimetallic aluminum(salen) complex.

73 The process is catalyzed by manganese salen complexes and uses nucleophilic fluorine sources,

74 Halide or alkoxide free yttrium-salen complexes are excellent catalysts for the ring ope

75 e synthesis of monofunctionalized Mn- and Co-salen complexes attached to a norbornene monomer via a s

76 catalyzed by chromium, cobalt, and aluminum salen complexes is reported.

77 condary alcohols catalyzed by chiral Mn(III)-salen complexes using HOBr, Br(2)/H(2)O/KOAc or PhI(OAc)

78 Chiral polymeric Co(III) salen complexes with chiral ((R)/(S)-BINOL, diethyl tart

79 of a series of oxidized nitridomanganese(V) salen complexes with different para ring substituents (R

80 ble synthetic catalysts (chiral cobalt-based salen complexes) have been used for the efficient asymme

81 ated with redox properties of the metal(III)(salen) complexes (Co > Fe > Mn), while differences in th

82 ss-linked micelles (SCMs) containing Co(III)-salen cores were prepared from amphiphilic poly(2-oxazol

83 Whereas the mechanism for the (salen)Cr(III)-catalyzed ARO of epoxides displays a squar

84 Preliminary investigations of this (salen)Cr(III)-catalyzed system for the coupling of propy

85 The air-stable, chiral (salen)Cr(III)Cl complex (3), where H(2)salen = N,N'-bis(

86 ohexene oxide or propylene oxide) using the (salen)Cr(III)Cl complex as catalyst, where H(2)salen = N

87 on pathway involving anionic six-coordinate (salen)Cr(N3)X- derivatives.

88 he reactions between (TPP)AlCl/DMAP and (R,R-salen)CrCl and rac-PO/S-PO/R-PO and CO(2), has been inve

89 d poly(cyclohexylene)carbonate catalyzed by (salen)CrN3 (H2salen = N,N,'-bis(3,5-di-tert-butylsalicyl

90 using TBHP as oxidant with a 2-quinoxalinol salen Cu(II) complex as catalyst is reported.

91 mouse leg tumor and tail melanoma models, Fe(Salen) delivery with magnet caused a robust decrease in

92 Chromium salen derivatives in the presence of anionic initiators

93 nganese(III) complexes of three fluorophilic salen derivatives were used to prepare ion-selective ele

94 iamine iron (Fe(Salen)), but not other metal salen derivatives, intrinsically exhibits both magnetic

95 and cyclohexene oxide catalyzed by chromium salen derivatives.

96 pathway include (1) the formation of a Mn(V)-salen dibromide, (2) its subsequent reaction with the al

97 iation (SID) of ternary complexes of Co(III)(salen)+, Fe(III)(salen)+, and Mn(III)(salen)+ with sever

98 weak director of absolute helicity in nickel-salen foldamers.

99 ly, electron withdrawing substituents on the salen framework resulted in a more redox stable Co(III)

100 Here, we show that an iron-salen, i.e., mu-oxo N,N'- bis(salicylidene)ethylenediami

101 Fe(Salen) is an anti-cancer compound with magnetic property

102 to both the electron-donating ability of the salen ligand and the [cocatalyst], where N-heterocyclic

103 s of a monocyclooct-4-en-1-yl functionalized salen ligand and the corresponding Co(II)(salen) complex

104 ymerization, and the interaction between the salen ligand and the growing polymer chain is a fundamen

105 ohexane-(1R,2R)-diamine) with a non-innocent salen ligand has been investigated both in the solid sta

106 A series of manganese Hangman salen ligand platforms functionalized by tert-butyl grou

107 minum initiator stabilized by a C2-symmetric salen ligand which shows a hitherto unknown high activit

108 hromium(III) system was achieved utilizing a salen ligand with tert-butyl groups in the 3,5-positions

109 mediated by the stepped conformation of the salen ligand, and not the shape of the chiral diamine ba

110 of hydrogen from carbon to an oxygen of the salen ligand.

111 e most widely used Schiff base ligands, the "salen" ligand, has been extensively researched.

112 iminophosphorane derivative of the popular "salen" ligand, termed "phosphasalen".

113 etic strategy for the construction of chiral salen ligands bearing two rigid xanthene spacers functio

114 1R,2R)-(-)-1,2-diaminocyclohexane to produce salen ligands featuring an expandable molecular cleft ca

115 e-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1:1:1 molar ratio of

116 onbiological molecules based on salophen and salen ligands that fold into single-stranded helices in

117 at could arise from tetradentate ligation of salen ligands to rhenium, one major isomer is observed a

118 The triplesalen ligand system based on three salen-like coordination environments bridged by a common

119 MR studies performed on 6 indicated that the salen macrocycle had rearranged upon thiirane coordinati

120 The addition of the steric groups to the salen macrocycle leads to enhanced catalase activity by

121 nder aerobic and acidic conditions, these Co(salen) macrocycles exhibit extremely high reactivities a

122 Two free radical scavengers, the salen-manganese complex EUK-134, and the spin trap s-PBN

123 This supports the concept that salen-manganese complexes represent a class of SOD and,

124 This study describes two series of salen-manganese complexes, comparing catalytic ROS scave

125 In previous papers, two salen-manganese complexes, EUK-8 and EUK-134, had supero

126 UK-8 is a member of a new class of synthetic salen-manganese compounds with low toxicity that possess

127 cterized as a side product of the nickel(II) salen mediated electroreductive cyclization of 11.

128 Salen metal complexes incorporating two chiral BINOL moi

129 ghly enantioselective addition reactions by (salen)metal catalysts to an important new class.

130 class of chiral 5,5'-di(2,4,6-trialkyl)aryl salen-metal complexes have been developed and shown to c

131 f macrocyclic oligomeric structures with the salen moieties being attached in an unsymmetrical, flexi

132 iral (salen)Cr(III)Cl complex (3), where H(2)salen = N,N'-bis(3,5-di-tert-butyl-salicylidene)-1,2-cyc

133 len)Cr(III)Cl complex as catalyst, where H(2)salen = N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cycl

134 o the characterization of the Mn(III) salen (salen = N,N'-ethylene bis(salicylideneaminato)) complex

135 compound [Ru(salen)(NO)(H(2)O)](SbF(6)) (1) (salen = N,N'-ethylene-bis-salicylidene aminate) reacts c

136 inum bromide compounds salen((t)Bu)AlBr (1) (salen = N,N'-ethylenebis(3,5-di-tert-butylsalicylideneim

137 reaction was established by isolation of [Ru(salen)(NO)(cis-stilbene sulfide)](SbF(6)) (6).

138 The compound [Ru(salen)(NO)(H(2)O)](SbF(6)) (1) (salen = N,N'-ethylene-bi

139 The method uses Mn(salen)OTs as an F-transfer catalyst and enables the faci

140 tron transfer during dissociation of Co(III)(salen)-peptide complexes is mainly determined by differe

141 on behavior was obtained for various Co(III)(salen)-peptide systems of different angiotensin analogue

142 ed by the cyclohexanediamine backbone of the salen platform is revealed by the epoxidation of 1,2-dih

143 ochemistry of the cyclohexyl backbone of the salen platform is revealed in the epoxidation of 1,2-dih

144 While nickel(II) salen proved effective, the analogous cobalt complex as

145 oxide, with this activity most influenced by salen ring alkoxy substitution and aromatic bridge modif

146 cellent enantioselectivities using a chiral (Salen)Ru(II) cyclopropanation catalyst in the key asymme

147 nique to the characterization of the Mn(III) salen (salen = N,N'-ethylene bis(salicylideneaminato)) c

148 ites, and the high local concentration of Co(salen) species resulting from the macrocyclic framework.

149 roperties which are not always observed with salen systems as a result of their pi-conjugation.

150 has been increased interest in pi-conjugated salen systems, known as "salphen" ligands, as a result o

151 six-coordinate cationic aluminum compounds [salen((t)Bu)Al(Ph(3)PO)(2)]Br (4), [salpen((t)Bu)Al(Ph(3

152 epare three Salen aluminum bromide compounds salen((t)Bu)AlBr (1) (salen = N,N'-ethylenebis(3,5-di-te

153 The alkane elimination reaction between Salen((t)Bu)H(2) ligands and diethylaluminum bromide was

154 The Salen(tBu) ligand and its derivatives were used to prepa

155 tive oxazaborolidine reduction and a chiral (salen)Ti(IV) catalyzed asymmetric synthesis of silyl cya

156 roups that can enhance enantioselectivity of salen titanium complexes when they are used in asymmetri

157 with laccases and other catalysts like a Co(salen) type catalyst and PdCl(2) clearly demonstrate tha

158 tization (HPD) reaction promoted by a chiral salen-type bis(lambda(5)-iodane) reagent, followed by an

159 when bis(3-pyridyl)-functionalized free-base salen-type ligand was employed in the reaction.

160 Zn(II)-metalation of the salen-type ligands in the molecular loops converts the l

161 with bis(4-pyridyl)-functionalized free-base salen-type ligands.

162 (2) and bis(4-pyridyl)-functionalized Zn(II)-salen-type ligands.

163 se in tumor size, and the accumulation of Fe(Salen) was visualized by magnetic resonance imaging.

164 o(III)(salen)+, Fe(III)(salen)+, and Mn(III)(salen)+ with several angiotensin peptide analogues was s