ライフサイエンスコーパス: salicylate

1 -methyl-5-hepten-2-one, benzaldehyde, methyl salicylate).

2 mechanisms (cyclooxygenase-2 inhibitors and salicylates).

3 idue is required for efficient production of salicylate.

4 rob systems function together in response to salicylate.

5 were resistant to these metabolic effects of salicylate.

6 in the LA were also dramatically altered by salicylate.

7 disappeared upon treatment of seedlings with salicylate.

8 tion was moderately increased in response to salicylate.

9 ter membrane porin expression in response to salicylate.

10 dually manipulated by the prestin inhibitor, salicylate.

11 for the ionophore I with chloride as well as salicylate.

12 tin biosynthesis by converting chorismate to salicylate.

13 p90 ribosomal S6 kinase (RSK) as a target of salicylate.

14 rin and indomethacin and minimally by sodium salicylate.

15 ivation by converting acetophenone to methyl salicylate.

16 esidues that could potentially interact with salicylate.

17 in cetyltrimethylammonium bromide and sodium salicylate.

18 hat contributes to the metabolic efficacy of salicylates.

19 e inhibition of protein synthesis induced by salicylates.

20 f the chemical warfare agent simulant methyl salicylate (1.24 ppb) and for nitrobenzene (629 pptr) ar

21 FVT of methyl salicylate-1-(13)C 7a revealed a deep-seated rearrangeme

22 uple hypothesis; however, the application of salicylate (10 mM), which inhibits electromotility, is n

23 in the AC, we used a micropipette to infuse salicylate (20 mul, 2.8 mM) into the amygdala.

24 The addition of a second dose of salicylate 4 h before an indicated endpoint suppressed C

25 arked increase in relative content of benzyl salicylate (43.30%) and a significant decrease in methyl

26 Salsalate (nonacetylated salicylate, 4500 mg/d), a compound that inhibits NF-kapp

27 Furthermore, high doses of aspirin or salicylate (5 mM), well above therapeutic plasma concent

28 -containing antibacterial agent, and 5-amino-salicylate (5-ASA), an anti-inflammatory agent.

29 sis (FVT) with Ar-matrix isolation of methyl salicylate (7), 2-phenylbenzo-1,3-dioxan-4-one (8), phth

30 rved labeling pattern in the isolated methyl salicylate 7a/7b and methyl cyclopentadienecarboxylates

31 Prior treatment with salicylate, a disrupter of the SSC, confirms the influen

32 Furthermore, we find that salicylate, a hormone involved in biotrophic defense tha

33 in opposite directions during treatment with salicylate, a known competitor of required chloride bind

34 Treatment with salicylate, a known inhibitor of NLC, reestablishes cont

35 Salicylate, a plant product, has been in medicinal use s

36 ed electrode was fabricated to detect methyl salicylate, a volatile organic compound released by path

37 against COX-2, with the exception of sodium salicylate (A549 cells).

38 g SA and methylsalicylate, as a reporter for salicylate accumulation in the apoplast of plant leaves.

39 HR lesions at 90 and 168 h post-inoculation, salicylate accumulation was detected predominantly in ti

40 on of salsalate or of aspirin at high doses, salicylate activates adenosine monophosphate-activated p

41 A single dose of salicylate added with LPS/IFNgamma inhibited NOS-2 expre

42 Salicylate administration (250 mg/kg) resulted in a sign

43 Salicylate, an amphiphilic molecule and a popular member

44 esence of both mutant proteins and synthetic salicylate analogues of Ent.

45 nd K44 significantly reduced binding to both salicylate and 2,4-dinitrophenol, while a mutation in re

46 e method for the rapid determination of five salicylate and benzophenone-type UV absorbing substances

47 pulations of nonlinear capacitance with both salicylate and chloride that an enhanced area motor mode

48 er, the movements were also diminished by Na salicylate and depended on the intracellular anion, prop

49 of the CD81-HCV interaction, namely, benzyl salicylate and fexofenadine, were shown to overlap the H

50 The results show that both salicylate and ibuprofen increase membrane disorder, as

51 of two nonsteroidal antiinflammatory drugs, salicylate and ibuprofen, with vesicles prepared from 1,

52 nts sprayed with methyl jasmonate and methyl salicylate and in excised leaves supplied through cut pe

53 The nonselective COX inhibitors salicylate and indomethacin enhanced the expression of i

54 The salicylate and isochorismate synthase activities of MbtI

55 tions regarding the biosynthetic role of the salicylate and its potential impact on the mechanism of

56 (JA) biosynthesis genes and exogenous methyl salicylate and methyl jasmonate applications showed that

57 lyase activity resulting in the formation of salicylate and pyruvate as the reaction products.

58 so of its complex with the reaction products salicylate and pyruvate at 1.85 A and 2.1 A resolution,

59 raphic structures are reported for K42A with salicylate and pyruvate bound and for apo-I87T.

60 It is a bifunctional enzyme that forms salicylate and pyruvate from chorismate and water via th

61 PchB physiologically produces salicylate and pyruvate from isochorismate for ultimate

62 Activation of AMPK by salicylate and the thienopyridone A-769662 is critically

63 -methoxy-3-(1-methylpropyl)-pyrazine, methyl salicylate and tridecane.

64 tabolites and drug-like molecules, including salicylates and diclofenac, as MR1-binding ligands.

65 ively minor effects were observed with other salicylates and PJ34.

66 Two structural series included the salicylates and the N-phenylanthranilic acids, and addit

67 ast but not least, together with jasmonates, salicylate, and abscisic acid, ethylene is important in

68 licylaldehyde, o-hydroxyacetophenone, methyl salicylate, and methyl N-methyl- or N-phenylanthranilate

69 oxib, meloxicam, naproxen, rofecoxib, sodium salicylate, and SC560 as inhibitors of COX-1 and COX-2 i

70 nas putida G7 cells were exposed to glucose, salicylate, and silver nanoparticles (AgNPs) and their m

71 rent salicylate-based drugs (aspirin, sodium salicylate, and sulfasalazine) on the development of ear

72 We examined the effects of sulfasalazine, salicylates, and the poly(ADP-ribose) polymerase-1 inhib

73 ling network, jasmonate, ethylene, PAD4, and salicylate, are disabled, the hypersensitive response (H

74 convergent synthesis of this agent using the salicylate as a novel molecular switch for the chemosele

75 otential amperometry using hydrolyzed methyl salicylate as the analyte.

76 BP2 has strong esterase activity with methyl salicylate as the substrate, and that SA is a potent pro

77 ated metabolites (5-hydroxy-L-tryptophan and salicylate) as activators of the aryl hydrocarbon recept

78 its voltage dependence and susceptibility to salicylate, as well as an associated chloride-sensitive

79 Intriguingly, salicylate/aspirin prevents the phosphorylation of AMPKa

80 aspirin to salicylate in humans and the high salicylate/aspirin ratios in serum, it is likely that th

81 We found that the HIPVs menthol and methyl salicylate at 1 and 10 nmol.ml(-1) improved many perform

82 We have reported previously that salicylate at 10(-5) M inhibited LPS/IFNgamma-induced CC

83 ations in residues shown as interacting with salicylate at SAL-A and SAL-B in the MarR-salicylate str

84 logues WN-2-WN-7 and the previously reported salicylate-based analogue WN-8 are described.

85 fects of oral consumption of three different salicylate-based drugs (aspirin, sodium salicylate, and

86 es in the retinal vasculature, and all three salicylate-based drugs inhibited this cell death and for

87 EFR-triggered immunity: the potentiation of salicylate-based immunity and the repression of a jasmon

88 homologue MTH313 suggested the presence of a salicylate binding site buried at the interface between

89 e MarR-salicylate structure had no effect on salicylate binding, indicating that these sites were not

90 to test which amino acids were essential in salicylate binding, we examined the role of residues tha

91 Salicylate binds at the same site as the synthetic activ

92 only its downstream promoters in response to salicylate but also the marRAB promoter.

93 cies of diclofenac, naproxen, rofecoxib, and salicylate, but not aspirin, celecoxib, indomethacin, lu

94 xide (DMSO), dimethylformamide (DMF), methyl salicylate, caffeine, l-leucine, l-histidine, loratadine

95 In this study, we find that salicylate can induce persister formation in Escherichia

96 motor model, including augmented deltaCsa by salicylate, can accurately account for our novel finding

97 teractions between ST1710 and three ligands, salicylate, carbonyl cyanide m-chlorophenylhydrazone (CC

98 sensitive to amphipathic compounds including salicylate, chlorpromazine (CPZ), and trinitrophenol (TN

99 The ferric salicylate complexes display quasi-reversible reduction

100 dose resulting in clinically relevant serum salicylate concentrations ( approximately 1 mmol/L).

101 Plasma salicylate concentrations reached the midtherapeutic ran

102 On the other hand, the fatty acid salicylate conjugate 11 has been shown to have a unique

103 fatty acid niacin conjugates and fatty acid salicylate conjugates.

104 inomycin A is a member of a new class of bis-salicylate-containing polyene macrodiolides, which have

105 43.30%) and a significant decrease in methyl salicylate content in spring bamboo shoots were observed

106 nown to undergo a change from catecholate to salicylate coordination in acidic conditions, which is p

107 While Scn binding hinders salicylate coordination transformation, strong acidifica

108 py was applied to investigate the effects of salicylate, CPZ, and TNP on di-8-ANEPPS orientation in t

109 Although salicylate decreased topo IIalpha ATPase activity in a d

110 etophenone was reduced, while that to methyl salicylate did not change.

111 A single dose of salicylate did not inhibit C-Rel binding at any time poi

112 d a plant-derived repellent compound, methyl salicylate, differed between morphs or sexes.

113 es (DDDs) of MRP inhibitors (NSAIDs, PDE5-i, salicylates, dipyridamole) were collected.

114 Salicylate directly activates AMPK via the beta1 subunit

115 re consistent and support a picture in which salicylate disrupts membrane stability by decreasing mem

116 ntially accumulates in the membrane, whereas salicylate does not.

117 We hypothesized that salicylates downregulate 11beta-HSD1 expression, contrib

118 mproves glucose homeostasis and NAFLD is via salicylate-driven mitochondrial uncoupling.

119 g by possible withholding of antiplatelet or salicylate drugs before invasive dental treatment or by

120 rsons with prescriptions for antiplatelet or salicylate drugs before treatment.

121 Salicylate effectively reduces the apparent area compres

122 it locus (QTL) linked to higher fruit methyl salicylate emissions.

123 The lobatamides and related salicylate enamide natural products are potent mammalian

124 Now, with Ir catalysis and low-cost salicylate esters, alkene oxyacylation can be promoted b

125 Oral aspirin (as a representative of the salicylate family) inhibited diabetes-induced increase i

126 catecholate [Fe(III)(Ent)](3)(-) to the tris-salicylate [Fe(III)(H(3)Ent)](0) upon protonation, the c

127 Both SERSAM and SER(3M)SAM form tris-salicylate ferric complexes with spectroscopic and solut

128 Birch reduction of the SEM ether of methyl salicylate followed by oxidation of the intermediate eno

129 -deficient mice and C57Bl/6 mice with sodium salicylate for 4 weeks.

130 ll guide the search for potent inhibitors of salicylate formation, and hence of bacterial iron uptake

131 hloride over major lipophilic anions such as salicylate ( [Formula: see text] ) and thiocyanate ( [Fo

132 y competent intermediate in the synthesis of salicylate from chorismate.

133 de bond rotation between the catecholate and salicylate geometries using the gallic complexes of ente

134 Methyl salicylate has been identified as one of the most import

135 This reduction of electromotility by salicylate has been widely studied, but the molecular me

136 Salsalate, a nonacetylated prodrug of salicylate, has been shown to decrease blood glucose con

137 tory drug aspirin and its metabolite, sodium salicylate, have profound effects on cellular protein sy

138 s of SA through the transgenic expression of salicylate hydroxylase (NahG) in both stably transformed

139 ased electrochemical biosensor consisting of salicylate hydroxylase and tyrosinase enzymes immobilize

140 er a mutation in EDS1 or the presence of the salicylate hydroxylase gene, NahG.

141 xpression of a C(2)H(4) biosynthesis gene in salicylate hydroxylase tobacco plants implicated transcr

142 Introduction of the Naphthalene/salicylate hydroxylase transgene, which suppresses SA ac

143 NahG encodes a salicylate hydroxylase, and expression in siz1-2 seedlin

144 We report, however, that in salicylate hydroxylase-expressing tobacco (Nicotiana tab

145 Challenging salicylate hydroxylase-expressing tobacco lines and tiss

146 ld-type levels by expressing nahG, bacterial salicylate hydroxylase.

147 high-affinity BSA and HSA binding sites for salicylate, ibuprofen and picosulfate by using these sen

148 Recent trials show salicylates improve glycemic control in type 2 diabetes,

149 In C57Bl/6 DIO mice, salicylate improved glucose tolerance and downregulated

150 olds during and after middle ear infusion of salicylate in artificial perilymph (AP), applied near th

151 based on the rapid metabolism of aspirin to salicylate in humans and the high salicylate/aspirin rat

152 trical and mechanical membrane properties by salicylate in the absence of cytoskeletal or membrane-bo

153 tilized to calculate the molecular volume of salicylate in the membrane.

154 -2 responded to both acetophenone and methyl salicylate in vivo.

155 te, both of which are rapidly broken down to salicylate in vivo.

156 the potential benefit of aspirin and natural salicylates in cancer prevention.

157 a useful new tool to non-destructively assay salicylates in situ and to map their spatial distributio

158 l for methyl salicylate synthesis and methyl salicylate, in turn, likely has an important role in con

159 Salicylates, in doses administrated in our experiments,

160 ally produces bioluminescence in response to salicylates including SA and methylsalicylate, as a repo

161 h 5-aminoimidazole-4-carboxamide riboside or salicylate increased nNOS S1412 phosphorylation and was

162 hese AMPK-independent effects, we found that salicylate increases oligomycin-insensitive respiration

163 d in the presence of a high concentration of salicylate indicated two possible salicylate sites, SAL-

164 We show here that salicylates induce phosphorylation of the alpha-subunit

165 Salicylate induced a significant increase of the gap-det

166 Aspirin and its major metabolite sodium salicylate induced apoptosis and decreased colon cancer

167 Exposure to salicylate induced smooth movement with few acceleration

168 We hypothesize that these salicylate-induced alterations jointly represent a uniqu

169 To determine if salicylate-induced changes restricted to the LA would re

170 t mounted normal local resistance and methyl salicylate-induced defense responses, suggesting that mo

171 Our findings reveal that salicylate-induced oxidative stress can lead to persiste

172 Salicylate-induced ROS cause a decrease in the membrane

173 These results suggest that salicylate-induced temporal processing deficits may be d

174 nd 20 kHz (frequencies near the pitch of the salicylate-induced tinnitus in the rat).

175 c stress via the locus coeruleus; [3] sodium salicylate induces an acute excitotoxicity by potentiati

176 In addition, salicylate induction upregulates two antibiotic target g

177 imental data and support the conclusion that salicylate influences the electrical but not the mechani

178 Second, salicylate influences the electrostatic potential and di

179 resholds were elevated reversibly during the salicylate infusion.

180 short-term diabetes (2-4 months), all three salicylates inhibited the diabetes-induced loss of neuro

181 All three salicylates inhibited the diabetes-induced translocation

182 lfasalazine (also as a representative of the salicylates) inhibited the diabetes-induced upregulation

183 proved by systemic neutralization of IL-6 or salicylate inhibition of IKK-beta.

184 We propose that salicylate inhibits C/EBPbeta binding at 4 h and C-Rel b

185 We conclude that salicylate inhibits C/EBPbeta-mediated COX-2 transcripti

186 e have now determined the mechanism by which salicylate inhibits topo II.

187 otopic shift in the amygdala and infusion of salicylate into the amygdala can profoundly enhance soun

188 chorismate for ultimate incorporation of the salicylate into the siderophore pyochelin.

189 Salicylate is a small amphiphilic molecule which has div

190 Salicylate is also able to stimulate brown adipose tissu

191 Our results demonstrate that salicylate is unable to intercalate DNA, and does not pr

192 y activate micF transcription in response to salicylate, leading to reduced OmpF expression.

193 lysis revealed that growth of S. aureus with salicylate leads to the induction of genes involved with

194 tion of plant volatiles, particularly methyl salicylate, making bean plants, Vicia faba, repellent to

195 The mechanical changes induced by salicylate may affect several biological processes, espe

196 We propose that aspirin/salicylate may augment metformin's hepatic action to sup

197 tein (ACP) domain of MbtB to form covalently salicylated MbtB-ACP.

198 noncompetitive manner, this was secondary to salicylate-mediated inhibition of DNA cleavage.

199 findings provide a definitive mechanism for salicylate-mediated inhibition of topo IIalpha and provi

200 Salicylate-mediated signaling has been implicated in oth

201 omponents elicited varying responses; Methyl salicylate (MeSA) elicited the highest positive chemotax

202 resistance (SAR) in tobacco; SABP2's methyl salicylate (MeSA) esterase activity is required in healt

203 netic backgrounds, we showed that the methyl salicylate (MeSA) esterase activity of salicylic acid-bi

204 SABP2 is a methyl salicylate (MeSA) esterase that has high affinity for SA

205 The first such signal identified was methyl salicylate (MeSA) in tobacco (Nicotiana tabacum).

206 Methyl salicylate (MeSA) is a volatile plant secondary metaboli

207 posure to methyl jasmonate (MeJA) and methyl salicylate (MeSA) vapours at 10 and 100micromoll(-1) was

208 h five GLVs: methyl jasmonate (MeJa), methyl salicylate (MeSa), cis-3-hexenyl acetate (HxAc), cis-3-h

209 ancer activity of aspirin is also due to the salicylate metabolite.

210 f jasmonate, but ethylene (ET) responses and salicylate modulate the resistance of hub1 mutants to ne

211 hid-induced VOCs (ethanone, limonene, methyl salicylate, myrcene, ocimene) triggered resistance in re

212 Recent studies found that salicylate not only affects outer hair cell motility in

213 To identify the physiological effects of salicylate on central auditory system function, the infe

214 tartle reflex was used to measure effects of salicylate on gap detection acuity.

215 ivity that displaces pyruvate to form either salicylate or anthranilate.

216 nse to pathogen infection, or treatment with salicylate or the paraquat herbicide that generates acti

217 tor (indomethacin), selective COX-1 (valeryl salicylate), or selective COX-2 (SC-236) inhibitors into

218 nduced by wounding, methyl jasmonate, methyl salicylate, or ethephon, synthetic GmSubPep peptide, whe

219 In mutants deficient in jasmonate, salicylate, or ethylene signaling, APR mRNA levels were

220 ey are induced by their respective inducers: salicylate, paraquat, and decanoate.

221 ants deficient in the jasmonate/ethylene and salicylate pathways, and in wild-type plants by treatmen

222 ertechnetate, etc.) or organic anions (e.g., salicylate, pharmaceuticals, and their metabolites, whic

223 result supports other findings that suggest salicylate primarily influences electromotiliy and OHC n

224 One of these is salicylate, probably the oldest medicinal agent known to

225 The salicylate prodrug salsalate has been shown to improve m

226 of SlyA bound to the small molecule effector salicylate (Protein Data Bank code 3DEU), reveal that, u

227 ponse to inducible substrate concentrations (salicylate) ranging from 250 to 5000 ppb.

228 ity of the cyclic amide through ring strain, salicylates reduce the electrophilicity of the aryl este

229 Both resveratrol and salicylate reduced the formation of tetraploid or higher

230 reus with the nonsteroidal anti-inflammatory salicylate reduces susceptibility of the organism to mul

231 o regulate cross-talk between jasmonate- and salicylate-regulated disease response pathways.

232 is associated with reduced expression of the salicylate-regulated PR-1 gene.

233 sensor can be used to reliably detect methyl salicylate released by unhealthy plants.

234 ither resveratrol or aspirin, the prodrug of salicylate, repressed the accumulation of tetraploid int

235 In this study, we investigated one aspect of salicylate's action, namely the perturbation of electric

236 Surprisingly, comparison of salicylate's effects using purified human topo IIalpha a

237 K1, EIN2, and HUB1 but not genes involved in salicylate (SA) functions.

238 Salicylate (SA, 2-hydroxybenzoate) is a phytohormone bes

239 nate, ethylene, phytoalexin-deficient 4, and salicylate sectors, which together govern up to 80% of t

240 n topo IIalpha and topo IIbeta revealed that salicylate selectively inhibits the alpha isoform.

241 Thus, salicylates selectively trigger an endoplasmic reticulum

242 Salicylate significantly reduced deposition of G7 cells

243 tration of salicylate indicated two possible salicylate sites, SAL-A and SAL-B.

244 Surprisingly, salicylate somewhat activates transcription of rob, whil

245 potential interference from anions including salicylate, sorbate, citrate, phosphate, acetate and chl

246 th salicylate at SAL-A and SAL-B in the MarR-salicylate structure had no effect on salicylate binding

247 However, salicylate supplement inhibited NOS-2 promoter activitie

248 The presence of CCCP and salicylate suppressed ST1710-ST1 interaction, indicating

249 ase (ADCS), isochorismate synthase (IS), and salicylate synthase (SS) are structurally homologous cho

250 other chorismate-utilizing enzymes, such as salicylate synthase and anthranilate synthase.

251 kinetic mechanisms of the isochorismate and salicylate synthase enzymes of siderophore biosynthesis.

252 e isochorismate synthase enzymes but not the salicylate synthase enzymes.

253 The bifunctional salicylate synthase MbtI catalyzes the first step of myc

254 The salicylate synthase, Irp9, from Yersinia enterocolitica

255 indicate that SlSAMT is critical for methyl salicylate synthesis and methyl salicylate, in turn, lik

256 The C-4 salicylate takes the place of the more common C-4 dimeth

257 ed significantly greater responses to methyl salicylate than to acetophenone.

258 efore and after treating rats with a dose of salicylate that induces tinnitus and hyperacusis-like be

259 Salsalate is a prodrug of salicylate that lowers blood glucose in patients with ty

260 tems with two AMPK activators, metformin and salicylate (the active form of aspirin).

261 The effects of aspirin, salicylate (the natural deacetylated form of aspirin), a

262 tabolites in SAR signaling, including methyl salicylate, the abietane diterpenoid dehydroabietinal, t

263 We previously identified salicylate, the primary metabolite of aspirin, as a nove

264 In AMPK knockout mice, effects of salicylate to increase fat utilization and to lower plas

265 ic acid binding protein 2) hydrolyzes methyl salicylate to salicylic acid.

266 Local delivery of salicylate to the amygdala significantly increased the a

267 a GDSL family acyltransferase that transfers salicylate to the C-4 hydroxyl of a tetracycline interme

268 First, binding of salicylate to the membrane displaces chloride from the b

269 ation, antiinflammatory strategies including salicylate treatment and genetic suppression of myeloid

270 s assessment of Clin, which increases during salicylate treatment as motors are locked in the expande

271 gether, these results indicate that systemic salicylate treatment can induce hyperactivity and tonoto

272 Although salicylate treatment did not trigger activation of inosi

273 tinomycin D treatment blocked, and high dose salicylate treatment inhibited by 80%, TNFalpha-induced

274 ession in subcutaneous adipose, and in vitro salicylate treatment reduced adipocyte 11beta-HSD1 expre

275 sidues that bind intracellular chloride, and salicylate treatment which prevents chloride binding, ha

276 recruit to aboveground herbivory and methyl salicylate treatment, that larval D. speciosa are relati

277 of intracellular chloride and was blocked by salicylate treatment.

278 Methyl salicylate undergoes hydrolysis to form methanol, which

279 Salicylate unexpectedly increased the amplitude of the l

280 opo II (alpha and beta), we examined whether salicylate was isoform selective.

281 Conversion of acetophenone to methyl salicylate was observed in the medium of CYP1a2-expressi

282 rticular, the interference from chloride and salicylate was reduced by 2 and 6 orders of magnitude, r

283 lementation of chemically defined media with salicylate was required for equibactin production.

284 The tension-dependent partitioning of salicylate was utilized to calculate the molecular volum

285 etween AERD and control subjects, and sodium salicylate was without effect.

286 c acyl chain region of the membrane, whereas salicylate weakly associates with the phospholipid headg

287 menting abilities of chloroquine and quinine salicylate were assessed in a human skin equivalent mode

288 ionone, hotrienol, methylpyrazine and methyl salicylate were major volatile constituents in all the e

289 yperglycemic and antiinflammatory effects of salicylates were not connected to the pathogenesis of in

290 Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in diabet

291 Using the well known ototoxicant, salicylate, which competes with the putative anion bindi

292 au acetylation is inhibited by salsalate and salicylate, which enhance tau turnover and reduce tau le

293 ed in the presence of the aspirin-derivative salicylate, which impaired activation of NF-kappaB p65 i

294 onds to phenolic compounds, including sodium salicylate, which inhibit its activity.

295 t ambient temperature comprise 12.30% methyl salicylate, which provides protection against insect att

296 plex to the hsp70 loci in cells treated with salicylate, which triggers chromatin remodeling at these

297 s also seen with equimolar concentrations of salicylate, while selective Cox inhibitors did not inhib

298 MP-activated protein kinase (AMPK) including salicylate, whose chemopreventive action has been establ

299 s pH value the enzyme converts chorismate to salicylate without the accumulation of isochorismate in

300 The synthesis of salicylate WN-8 is accomplished through the union of fra