ライフサイエンスコーパス: salvage pathway

1 se in the recycling of the backbones via the salvage pathway.

2 -gamma-methiolbutyrate closes the methionine salvage pathway.

3 es from the de novo pathway and 20% from the salvage pathway.

4 er, R. rubrum lacks the classical methionine salvage pathway.

5 osphate, an important step in the pyrimidine salvage pathway.

6 ion of ethylene, a product of the methionine salvage pathway.

7 ly available to be absorbed and used for the salvage pathway.

8 ted by repletion of CTP through the cytidine salvage pathway.

9 tion of ARDs is to operate in the methionine salvage pathway.

10 de and generates NAD+ through an alternative salvage pathway.

11 sphorylase (PNP) is part of the human purine salvage pathway.

12 to refill the internal GMP pool through the salvage pathway.

13 sphorylase is a key enzyme in the pyrimidine salvage pathway.

14 sing the de novo biosynthesis pathway or the salvage pathway.

15 d from M. bovis, demonstrating a functioning salvage pathway.

16 critically requires the deoxyribonucleoside salvage pathway.

17 MA-induced formation of ceramide through the salvage pathway.

18 ase (Nampt) is a rate-limiting enzyme in the salvage pathway.

19 hosphorylase, a key enzyme in the methionine salvage pathway.

20 at provides a rate-limiting step in the NAD+ salvage pathway.

21 acterized, one of which is linked to a novel salvage pathway.

22 a requirement for the Preiss-Handler NAD(+) salvage pathway.

23 important gene in the Preiss-Handler NAD(+) salvage pathway.

24 a new PET probe for the deoxyribonucleotide salvage pathway.

25 hase LASS 5, demonstrating the action of the salvage pathway.

26 that AtNIC1 participates in a yeast-type NAD salvage pathway.

27 parasites due to the absence of a pyrimidine salvage pathway.

28 on of protein transport through a nucleoside salvage pathway.

29 n of rP nucleotide formation by a nucleotide salvage pathway.

30 nitial phosphorylation step in the thymidine salvage pathway.

31 tate (PMA) produced ceramide formed from the salvage pathway.

32 ose analog into glycoproteins via the fucose salvage pathway.

33 enzymes involved in the pyridoxal phosphate salvage pathway.

34 Thus, C. elegans lacks a functional fucose salvage pathway.

35 important role in the pyridoxal 5' phosphate salvage pathway.

36 amotoi had purA and purB genes of the purine salvage pathway.

37 oxygenases are key enzymes in the methionine salvage pathway.

38 to compensate by increasing flux through the salvage pathway.

39 prevalent metabolite in the bacterial purine salvage pathway.

40 ase (MTAP) is a key enzyme in the methionine salvage pathway.

41 ls to activate human PXR or induce the CYP3A-salvage pathway.

42 ochondrial enzyme of the deoxyribonucleoside salvage pathway.

43 also an increased reliance on the pyrimidine salvage pathway.

44 )CH(2)COCH(OH)=CH(OH) (I), in the methionine salvage pathway.

45 se (UPase) is a key enzyme in the pyrimidine salvage pathway.

46 ne phosphorylase (MTAP), a key enzyme in the salvage pathway.

47 rent pathways, the recycling pathway and the salvage pathway.

48 aci-reductone intermediate in the methionine salvage pathway.

49 d that their function is confined to the PLP salvage pathway.

50 bosyltransferase, a key enzyme in the purine salvage pathway.

51 ferase (MtHGPRT), a key enzyme of the purine salvage pathway.

52 )ation and being a constituent of the NAD(+) salvage pathway.

53 l phenotype relationship with the nucleoside salvage pathway.

54 steine, or of any compound in the methionine salvage pathway.

55 ed as a competitive substrate for the ribose salvage pathway.

56 the diet, which restored fucosylation via a salvage pathway.

57 mide phosphoribosyltransferase in the NAD(+) salvage pathway.

58 l regulation of cell death by the methionine salvage pathway.

59 CK), a key enzyme in the deoxyribonucleoside salvage pathway.

60 that INAM increases flux through the NAD(+) salvage pathway.

61 e combined action of NAD(+) biosynthesis and salvage pathways.

62 Nucleotides are synthesized from de novo and salvage pathways.

63 enesis, de novo synthesis as well as the two salvage pathways.

64 sis is regulated by both the de novo and the salvage pathways.

65 host, the parasite does not have pyrimidine salvage pathways.

66 cleotide synthesis pathways predominate over salvage pathways.

67 ituting two independent and essential purine salvage pathways.

68 nucleotides that they purportedly obtain by salvage pathways.

69 ospholipid (re)synthesis by both de novo and salvage pathways.

70 nt because of the preservation of nucleoside salvage pathways.

71 Xdh is required for purine salvage pathways.

72 llows minimal BH4 production through the BH4 salvage pathways.

73 limiting BH4 rescue through NADPH-dependent salvage pathways.

74 pyrimidine nucleotides via both de novo and salvage pathways.

75 flux, the pentose phosphate pathway, and NAD salvaging pathways.

76 salvages Cbi using both of the predicted Cbi salvaging pathways.

77 CTP originates from two sources: a salvage pathway and a de novo synthesis pathway that dep

78 PT is the rate-limiting enzyme of the NAD(+) salvage pathway and enhances SIRT1 activity by increasin

79 e spirochete is the first step in the purine salvage pathway and may represent a novel therapeutic ta

80 hydrolase is a central enzyme in the purine salvage pathway and represents a prime target for the de

81 Dietary fucose enters a salvage pathway and spares the mice.

82 yamine metabolism and adenine and methionine salvage pathways and was believed to be encoded as a sin

83 possesses this pathway, termed the thymidine salvage pathway, and can utilize thymidine as a total py

84 EHYDROGENASE1 (XDH1), involved in the purine salvage pathway, and CYTOSOLIC THIOURIDYLASE SUBUNIT1 an

85 ch point between the de novo pathway and the salvage pathway, and has been shown to be a rate-limitin

86 ferase (HPRT1) is a key enzyme in the purine salvage pathway, and mutations in HPRT1 cause Lesch-Nyha

87 in vitro, that each enzyme in the hexosamine salvage pathway, and the enzymes that affect this dynami

88 hway of regulated formation of ceramide, the salvage pathway, and they define a role for this pathway

89 pen up new avenues of research in nucleoside salvage pathways, and enhance our understanding of the p

90 Moreover, the aerobic and anaerobic sulfur salvage pathways appear to be differentially controlled,

91 Homologues for enzymes involved in a fucose salvage pathway are apparently absent in the P. falcipar

92 fectious cycle, as key enzymes in the purine salvage pathway are essential for the ability of the spi

93 Two key enzymes in purine salvage pathways are IMP dehydrogenase (GuaB) and GMP sy

94 In addition, sulfur salvage pathways are necessary to ensure that key sulfur

95 Purine salvage pathways are predicted to be present from the ge

96 Our work highlights pabA and the pyrimidine salvage pathway as potential targets for novel therapeut

97 he activation of caspase-7, and identify the salvage pathway as the critical mechanism of ceramide ge

98 and requires an intact mitochondrial NAD(+) salvage pathway as well as the mitochondrial NAD(+)-depe

99 versal pathways) and variable (recycling and salvage pathways) aspects of this subsystem.

100 ion of xanthine dehydrogenase affects purine salvaging pathways at the onset of development, creating

101 gly, fumonisin B1 (FB1), an inhibitor of the salvage pathway, attenuated loss of phosphorylation of p

102 ivity was not a result of recruitment of the salvage pathway based on the presence of adequate dTTP p

103 s extend current knowledge of the nucleotide salvage pathway by revealing the metabolism of oxidized

104 e catalyzes the first step in the nucleotide salvage pathway by transferring a phosphate group to a t

105 (ATR) reduces the output of both de novo and salvage pathways by regulating the activity of their res

106 egulates ceramide metabolism mainly from the salvage pathway, by positively regulating the expression

107 ere intriguing differences in key nucleotide salvage pathways: C.pneumoniae has a uridine kinase gene

108 Here, we show that the hexosamine salvage pathway can convert GlcNGc to UDP-GlcNGc, which

109 al component of the mitochondrial nucleotide salvage pathway, can give rise to mitochondrial DNA (mtD

110 hich catalyzes the first step of this NAD(+) salvage pathway, cannot mate due to a spicule muscle def

111 duct, mammalian cells have evolved an NAD(+) salvage pathway capable of resynthesizing NAD(+) from ni

112 However, another NAD(+) salvage pathway component, Pnc1, modulates silencing ind

113 The addition of the penultimate salvage pathway compound 4-methylthio-2-oxobutanoic acid

114 purine auxotroph possessing a unique purine salvage pathway consisting of a bacterial type purine nu

115 by UPRT, and that both the biosynthetic and salvage pathways contribute to a robust infection of the

116 Additionally, the two nicotinamide riboside salvage pathways contribute to NAD(+) metabolism in the

117 A combination of de novo and salvage pathways contribute to the biosynthesis of NAD i

118 These findings indicate that salvage pathway defects are not causally related to meth

119 C. glabrata salvage pathways defined in this article allow NAD(+) to

120 reduced expression of a putative methionine salvage pathway dehydratase, apoptotic protease activati

121 d nicotinamide riboside (NR) in the amidated salvage pathway despite no increase in nicotinamide phos

122 Here we show that enzymes of the nucleotide salvage pathway display substrate selectivity, effective

123 osphatiylserine decarboxylation, a potential salvage pathway, does not appear to be active in culture

124 tes of de novo dTMP synthesis, and increased salvage pathway dTMP biosynthesis relative to control fi

125 ed flux through the amidated arm of the NAD+ salvage pathway due to reduced sirtuin activity.

126 owth in a mouse, proving that the functional salvage pathway enables nicotinamide acquisition by the

127 , but mutants lacking the (redundant) purine salvage pathway enzyme adenosine kinase are susceptible

128 mtp53 creates a dependency on the nucleoside salvage pathway enzyme deoxycytidine kinase for the main

129 rosarcoma cell line and study how methionine salvage pathway enzyme methylthioadenosine phosphorylase

130 ch is then used as a substrate by the NAD(+) salvage pathway enzyme NA phosphoribosyltransferase (Npt

131 Finally, alterations in the NAD salvage pathway enzyme nicotinamide phosphoribosyltransf

132 wered NAD+ levels by downregulating the NAD+ salvage pathway enzyme nicotinate phosphoribosyltransfer

133 phoribosyltransferase (UPRT) is a pyrimidine salvage pathway enzyme that catalyzes the conversion of

134 opment, one is adenosine deaminase--a purine salvage pathway enzyme, and the last is a phosphatase, C

135 w that Npt1 and a previously uncharacterized salvage pathway enzyme, Nma2, are both concentrated in t

136 n wt strains and in strains lacking key NAD+ salvage pathway enzymes (PNC1 and NPT1).

137 rthermore, we revealed that both de novo and salvage pathway enzymes contribute to viral DNA replicat

138 ear ribonucleoprotein (hnRNP) A1 regulates a salvage pathway facilitating internal ribosome entry sit

139 Therefore, these proteins may provide a salvage pathway for dissociated tubulin heterodimers and

140 ved by modulating dietary fucose to supply a salvage pathway for GDP-fucose synthesis.

141 nt with an alpha-galactosidase A-independent salvage pathway for globotriaosylceramide degradation.

142 endent crosstalk between the proteins in the salvage pathway for NAD(+) biosynthesis and the proteaso

143 ctedly, overexpression of other genes in the salvage pathway for NAD(+) biosynthesis, including QNS1,

144 oes not require the presence of a functional salvage pathway for NAD(+) biosynthesis, SIR2 or an acti

145 S)-mediated cap-independent translation is a salvage pathway for protein expression when mTOR is inhi

146 This enzyme is part of a salvage pathway for reutilization of L-fucose and is als

147 kinase activity and up-regulates cers2b as a salvage pathway for sphingosine turnover.

148 yme, GalNAc kinase, has been implicated in a salvage pathway for the reutilization of free GalNAc der

149 encing and is dependent upon the de novo and salvage pathways for NAD(+) synthesis but is not correla

150 mutants, which are defective in de novo and salvage pathways for NAD(+) synthesis, respectively.

151 Recent genetic evidence reveals additional salvage pathways for NAD(+) synthesis.

152 S1) transporters are essential components of salvage pathways for nucleobases and related metabolites

153 The data are consistent with a salvaging pathway for cobinamide in which an amidohydrol

154 We propose a model for the complete salvage pathway from exogenous N-ribosylnicotinamide to

155 m glucose, just before intersection with the salvage pathway from free mannose.

156 ack loop to limit autophagy and prevent this salvage pathway from inducing RIPK1-dependent necroptoti

157 AMPT), catalyzing the first reaction in the "salvage" pathway from nicotinamide, showed potent antitu

158 ed to be dispensable when the nondeamidating salvage pathway functioned as the only route of NAD biog

159 Deletion of another NAD(+) salvage pathway gene called PNC1 caused a less severe si

160 Mutations in putative salvage pathway genes downstream of MTAP also cause elev

161 thway genes revealed an up-regulation of the salvage pathway genes in vivo and in vitro under conditi

162 Bordetella parapertussis have the recycling/salvage pathway genes pncA and pncB, for use of nicotina

163 alysis of the de novo synthesis and putative salvage pathway genes revealed an up-regulation of the s

164 ificant increases in expression of the known salvage pathway genes, PDX3 and SOS4.

165 Additional copies of the salvage pathway genes, PNC1, NMA1, and NMA2, increase te

166 creased expression was more dramatic for the salvage pathway genes.

167 containing both exogenous components of the salvage pathway, GlcNAc transporter NGT1 from Candida al

168 in genes which encode enzymes in the purine salvage pathway have long been recognized as rare causes

169 novo has been extensively characterized, the salvage pathways have received comparatively little atte

170 is an important component of the nucleotide salvage pathway in apicomplexan parasites and a potentia

171 ur results suggest that enhancing the NAD(+) salvage pathway in astrocytes could be a potential thera

172 ase to the mitochondria also enhances NAD(+) salvage pathway in astrocytes.

173 Thus, there is an active sphingolipid salvage pathway in both neurons and oligodendrocytes.

174 These results demonstrate a role for the salvage pathway in feedback inhibition of p38.

175 ts confirmed the presence of a robust purine salvage pathway in H. pylori.

176 es are likely to be active in the nucleotide salvage pathway in human cells, suggesting new designs f

177 t of a pyridoxal reductase in the vitamin B6 salvage pathway in plants.

178 fy a novel role for CerS and the sphingosine salvage pathway in regulating membrane permeability in t

179 and is an important member of the pyrimidine salvage pathway in those organisms.

180 iled comparative genomic study of the purine salvage pathway in various apicomplexan species highligh

181 e 1-phosphate (DK-MTP 1-P) in the methionine salvage pathway in which 5-methylthio-d-ribose (MTR) der

182 The pathways and enzymes of the NAD salvage pathway in yeast and animals, which diverge at n

183 egies to reconstitute an efficient thymidine salvage pathway in yeast.

184 tion of hydroxylbenzoates, and the thymidine salvage pathways in certain organisms.

185 ion of the interplay between the de novo and salvage pathways in DNA synthesis with respect to enviro

186 nally, the redundancy of functional upstream salvage pathways in GAS species narrows the choice of po

187 rs are essential for nucleotide synthesis by salvage pathways in hemopoietic and other cells that lac

188 de new information for purine and pyrimidine salvage pathways in Leishmania.

189 lase" reaction in the well-known "methionine salvage" pathway in Bacillus sp. and (2) the 5-methylthi

190 e environment, suggesting the existence of a salvaging pathway in this archaeon.

191 fic alterations in both the NAD+ de novo and salvage pathways including striking accumulations of nic

192 horibosyltransferase critical for the NAD(+) salvage pathway, increases Sir2-dependent silencing, sta

193 tfkgp mutant that is defective in the fucose salvage pathway indicates that 2F-Fuc must be converted

194 hrough the N-acetyl-D-galactosamine (GalNAc) salvage pathway induced abrogation of MAL-II and PNA epi

195 methyl)-2-methylpyrimidine (FAMP), a thiamin salvage pathway intermediate, into cells.

196 e role of NAD(+) metabolites/derivatives and salvage pathway intermediates as activators, inhibitors,

197 We introduced an exogenous GlcNAc salvage pathway into yeast, allowing cells to metabolize

198 tate) induces ceramide formation through the salvage pathway involving, in part, acid beta-glucosidas

199 Therefore, interference with the purine salvage pathway is an attractive therapeutic target.

200 , taken together, suggest that the thymidine salvage pathway is compartmentalized so that TMP kinase

201 or and cytosine, suggest that the nucleotide salvage pathway is essential for E. chaffeensis replicat

202 ion of the de novo pathway compared with the salvage pathway is not fully understood.

203 novo purine biosynthesis; hence, the purine salvage pathway is of potential therapeutic interest.

204 The purine salvage pathway is redundant and contains two routes to

205 An active NAD(+) salvage pathway is required for optimal function of each

206 l in which increased flux through the NAD(+) salvage pathway is responsible for the Sir2-dependent ex

207 ique feature of the Toxoplasma gondii purine salvage pathway is the expression of two isoforms of the

208 The first step in the salvage pathway is transport across the plasma membrane.

209 Giardia lamblia, a key enzyme in the purine salvage pathway, is a potential target for anti-giardias

210 me in the cytosolic deoxyribonucleoside (dN) salvage pathway, is an important therapeutic and positro

211 lase (UPase), a key enzyme in the pyrimidine salvage pathway, is associated with the intermediate fil

212 (MTAP), the initial enzyme in the methionine salvage pathway, is deleted in a variety of human tumors

213 tical enzyme in the mitochondrial pyrimidine salvage pathway, is essential for mitochondrial DNA (mtD

214 ynthesis pathway, rather than the nucleoside salvage pathway, is used to label DNA; the deoxyribose r

215 itional because PA can be shuttled through a salvage pathway (Kennedy pathway) by adding choline to t

216 zes an off-pathway shunt from the methionine salvage pathway leading to the production of formate, me

217 ing the stringent response to promote purine salvage pathways, maintain GTP homeostasis and ensure co

218 firms that enzymes common to the de novo and salvage pathways may be good drug targets.

219 uctone dioxygenase (ARD) from the methionine salvage pathway (MSP) is a unique enzyme that exhibits d

220 ion as tautomerases/enolases in a methionine salvage pathway (MSP).

221 organisms possess the "universal" methionine salvage pathway (MSP).

222 we report the identification of yeast purine salvage pathway mutants that are synthetically lethal wi

223 ucleotide deficiency, RS, and the nucleoside salvage pathway (NSP) enzymes deoxycytidine kinase (dCK)

224 de novo pathway (DNP) and by the nucleoside salvage pathway (NSP).

225 is down-regulated by LPS and functions as a salvage pathway of anandamide synthesis when the PLC/pho

226 The purine salvage pathway of Anopheles gambiae, a mosquito that tr

227 ponse to PMA revealed that PMA activated the salvage pathway of ceramide formation and not the de nov

228 ation of protein kinase C (PKC) promotes the salvage pathway of ceramide formation, and acid sphingom

229 gomyelin and glucosylceramide leading to the salvage pathway of ceramide formation.

230 n conjunction with tracers for the thymidine salvage pathway of DNA synthesis, because thymidine cont

231 midase (PNC), the first enzyme in the NAD(+) salvage pathway of invertebrates.

232 oxygenase (ARD) isozymes from the methionine salvage pathway of Klebsiella ATCC 8724 present an unusu

233 Unlike many components of the purine salvage pathway of L. donovani, both ASL and ADSS are cy

234 ferase (HGPRT) is a key enzyme in the purine salvage pathway of many protozoan parasites.

235 yrazinamidase (PncA) is involved in the NAD+ salvage pathway of Mycobacterium tuberculosis and other

236 ribosyltransferase involved in the mammalian salvage pathway of NAD synthesis.

237 ene encoding the rate-limiting enzyme in the salvage pathway of NAD(+) biosynthesis.

238 ase (NAMPT) is a rate-limiting enzyme in the salvage pathway of nicotinamide adenine dinucleotide bio

239 This enzyme is important in the salvage pathway of nucleoside recycling.

240 on to fcy2Delta and hpt1Delta mutants in the salvage pathway of purine nucleotide biosynthesis, mutan

241 amine (PM) kinase thought to function in the salvage pathway of pyridoxal 5'-phosphate (PLP) coenzyme

242 ly, are the only known genes involved in the salvage pathway of pyridoxal 5'-phosphate in plants.

243 The salvage pathway of the bovine tubercle bacillus Mycobact

244 this idea, we attempted to block the purine salvage pathway of the parasitic protozoan Tritrichomona

245 assess the relative roles of the de novo and salvage pathways of GDP-mannose biosynthesis.

246 e analogs to capitalize on the highly active salvage pathways of Leishmania, which are purine auxotro

247 lexible in participating in both de novo and salvage pathways of NAD synthesis.

248 an intrinsic mRNA-specific protein synthesis salvage pathway operative in glioblastoma (GBM) tumor ce

249 generation of NAD(+) from nicotinamide via a salvage pathway or by de novo synthesis of NAD(+) from t

250 in noncycling cells, are generated either by salvage pathways or through de novo synthesis.

251 rse metabolic pathways, including the uracil salvage pathway, oscillate in a circadian fashion and in

252 model in which two components of the NAD(+) salvage pathway, Pnc1p and Npt1p, function together in r

253 Gpd1p as well as a key enzyme of the NAD(+) salvage pathway, Pnc1p; (ii) Pnc1p, a nicotinamidase wit

254 th on Hcy, although it could now grow on the salvage pathway precursor methylthioadenosine.

255 ad development results from depletion of the salvage pathway product NAD(+), whereas the uv1 cell nec

256 l regulatory pathway in which the methionine salvage pathway products inhibit ODC activity.

257 The NAD(+) salvage pathway protein, Npt1, regulates Sir2-mediated p

258 One of the pivotal enzymes in its purine salvage pathway, purine nucleoside phosphorylase (PNP),

259 e pool of ceramide involved derives from the salvage pathway rather than de novo biosynthesis.

260 results show that products of the methionine salvage pathway regulate polyamine biosynthesis and sugg

261 luorouracil (5-FU) activation and pyrimidine salvage pathway regulation.

262 +) biosynthesis genes while the genes in the salvage pathway remain unaffected.

263 a formed from the protein kinase C-dependent salvage pathway results at least in part from the action

264 s mainly synthesized in human cells via the "salvage" pathways starting from nicotinamide, nicotinic

265 subunit proteins of the Calvin cycle and AMP salvage pathways suggests a strong biological role in hi

266 f glutaminolysis and triggers autophagy as a salvage pathway supporting leukemia cell metabolism.

267 n of NAD(+) levels by stimulating the NAD(+) salvage pathway suppressed mitochondrial protein hyperac

268 istance in Leishmania spp., as it provides a salvage pathway that bypasses dihydrofolate reductase (D

269 This defines a critical salvage pathway that can be autoinduced to minimize trio

270 enase (Fe-ARD'), an enzyme in the methionine salvage pathway that catalyzes the regiospecific oxidati

271 transferase, the rate-limiting enzyme in the salvage pathway that converts nicotinamide to NAD (mNAMP

272 It is part of the purine salvage pathway that has been identified only in eukaryo

273 oxidase (PDX3), have been identified in the salvage pathway that interconverts between the six vitam

274 nce of Cryptosporidium parasites on a single salvage pathway that leads to essential purine derivativ

275 and plants, most higher organisms rely on a salvage pathway that phosphorylates either pyridoxal (PL

276 atal Fc receptor, FcRn mediates an endocytic salvage pathway that prevents degradation of IgG, thus c

277 occurs either de novo or through one of the salvage pathways that converge at the point where the re

278 NAD+ metabolism in the de novo, import, and salvage pathways that originate from tryptophan (or aspa

279 an biosynthesize PLP de novo, they also have salvage pathways that serve to interconvert the differen

280 rresponding UDP sugar-donor by the canonical salvage-pathway that requires phosphorylation at the 6-h

281 lization, polyamine biosynthesis, the purine salvage pathway, the methionine salvage pathway, the SAM

282 , the purine salvage pathway, the methionine salvage pathway, the SAM radical pathways, autoinducer-2

283 ctionally address the role of the pyrimidine salvage pathway, the uridine phosphorylase (UP) salvage

284 s, and extend the function of the Rad1/Rad10 salvage pathway to 3'-phosphates.

285 we probe the contribution of the NAM-NAD(+) salvage pathway to muscle development and function using

286 pression of multiple NAD(+) biosynthesis and salvage pathways to promote homeostasis during stationar

287 To characterize the uridine salvage pathway, two genes, UKL1 and UKL2, that tentativ

288 Following the GalNAc salvage pathway, UDP-GalNGc is epimerized to UDP-GlcNGc,

289 mor proliferation as a function of thymidine salvage pathway utilization.

290 From these latter CDSs, an NAD salvage pathway was inferred that appears to be unique a

291 the bacterium Salmonella enterica, whose Cbi-salvaging pathway was blocked.

292 volved in the hydroxymethyl pyrimidine (HMP) salvage pathway, was solved by the multiwavelength anoma

293 s depleted and metabolites of the deamidated salvage pathway were reduced but intracellular NAD+ and

294 inase (TK) is a key enzyme in the pyrimidine salvage pathway which catalyzes the transfer of the gamm

295 rase 1 (NMNAT-1) constitute a nuclear NAD(+) salvage pathway which regulates the functions of NAD(+)-

296 , one of the major enzymes of the nucleoside salvage pathway, which affects peripheral T cell homeost

297 horylase (PNP) is a key enzyme in the purine salvage pathway, which provides an alternative to the de

298 Part of this effect was mediated by the NR salvage pathways, which generate NAM as a product and re

299 that supplementation of BH4 (via the pterin salvage pathway with Sep) increased Akt/eNOS phosphoryla

300 the rate-determining step in the nucleoside salvage pathway within all domains of life where the pat