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1 the presence of Leishmania in the gut of the sand fly.
2 sruption of transmission by the phlebotomine sand fly.
3 rasite patches that govern infectiousness to sand flies.
4 y blood-feeding female Lutzomyia longipalpis sand flies.
5 an hosts by the bites of bloodsucking vector sand flies.
6  long-term reservoir of infection for vector sand flies.
7 g-term reservoir of infection back to vector sand flies.
8 ania mexicana-infected Lutzomyia longipalpis sand flies.
9 eficient mice challenged by bite of infected sand flies.
10 Leishmania major metacyclic promastigotes by sand flies.
11  vaccinated dogs that are also infectious to sand flies.
12 d are transmitted by bites from phlebotomine sand flies.
13 ckettsia were reported for the first time in sand flies.
14 Fabaceae family was detected in 94.7% of the sand flies.
15 ism of Leishmania transmissibility to vector sand flies.
16 nated papers was determined with wild-caught sand flies.
17 ansmitted to the vertebrate host by infected sand flies.
18                        All patients infected sand flies.
19 cted long term when challenged with infected sand flies.
20  were used to coinfect Lutzomyia longipalpis sand flies.
21  following a natural challenge with infected sand flies.
22 st bite in volunteers exposed to colony-bred sand flies.
23 isceral leishmaniasis (VL) is transmitted by sand flies.
24  distribution reduces the expected number of sand flies acquiring parasites, it increases the infecti
25 s papatasi, and to maintain infection in the sand fly after excretion of the digested bloodmeal.
26  to endogenous self-Dsg1 and exogenous LJM11 sand fly Ag.
27 phoglycans (lpg2-) were unable to survive in sand flies and macrophages, but retained the ability to
28 ternate between flagellated promastigotes in sand flies and nonflagellated amastigotes in mammals, ca
29  life cycle involving transmission by biting sand flies and replication within mammalian macrophage p
30 n of molecules present in the midgut of this sand fly and the transcripts potentially modulated by bl
31 rast to bloodsucking Nematocera (mosquitoes, sand flies, and black flies), appear to concentrate a go
32 is study, we show that salivary Ags from the sand fly, and specifically the LJM11 salivary protein, a
33                                 Phlebotomine sand flies are hematophagous insects that harbor bacteri
34                                              Sand flies are the exclusive vectors of the protozoan pa
35                                 Phlebotomine sand flies are the vectors of medically important Leishm
36 e, we demonstrate that gut microbes from the sand fly are egested into host skin alongside Leishmania
37  the Leishmania parasites and the gut of the sand fly are poorly understood.
38 attractive to a greater proportion of female sand flies as the infection progresses.
39 fter feeding on the Leishmania that uses the sand fly as a vector.
40 athogen, and the Leishmania that utilize the sand fly as a vehicle for transmission between mammalian
41  the way to function characterization of the sand fly associated microbiome.
42 ave identified the first representative of a sand fly-associated flavivirus, Ecuador Paraiso Escondid
43 icantly more attractive to 50% of the female sand flies at the end of infection compared to before in
44 icantly more attractive to 75% of the female sand flies at the end of infection.
45 vade and exploit the innate host response to sand fly bite in order to establish and promote disease.
46 hallenge with L. major by needle or infected sand fly bite in resistant C57BL/6 mice.
47 stained neutrophilic infiltrate at localized sand fly bite sites.
48 are introduced into mammalian skin through a sand fly bite, but different species cause distinct clin
49              Following challenge by infected sand fly bite, polyprotein-vaccinated animals had compar
50 ds were transmitted to the mammalian host by sand fly bite.
51 o protection following challenge by infected sand fly bite.
52 te the durability and T(H)1 nature of DTH to sand fly bites in humans living in a cutaneous leishmani
53                      The relevance of DTH to sand fly bites in humans living in a leishmaniasis-endem
54 ns have proven to be effective in preventing sand fly bites, and subsequently infection.
55 vary gland homogenates (SGHs) or by infected sand fly bites.
56 ir vertebrate hosts by infected phlebotomine sand fly bites.
57 leishmaniasis have established infection via sand fly bites.
58                    This represents the first sand fly-borne flavivirus identified in the New World.
59 replication of vesicular stomatitis virus in sand fly cells and resulted in strains that initially re
60 s, isolated from mosquitoes and phlebotomine sand flies collected in Brazil, Peru, the United States,
61 rior exposure of mice to bites of uninfected sand flies conferred powerful protection against Leishma
62 ion for developing intervention strategy for sand fly control.
63 cted dogs and household spraying to kill the sand fly) could be effective, but have proven hard to ma
64       To mimic natural transmission, we used sand fly-derived metacyclic forms of L. major and preexp
65 ration of immune homeostasis in phlebotomine sand flies during the growth of bacterial and Leishmania
66 profile of certain midgut transcripts in the sand fly during blood meal digestion and that this modul
67              Identifying genes important for sand fly ecological adaptability and sand fly-Leishmania
68  greatly facilitate the understanding of the sand fly ecology, which would provide critical informati
69                                     Notably, sand flies efficiently acquired parasites after feeding
70                      The bites of uninfected sand flies favor the transmissibility of L. donovani by
71                                              Sand flies feeding at sites in mouse ears that had a DTH
72 rasites, it increases the infection load for sand flies feeding on a patch, increasing their potentia
73      Importantly, 45.6%, 50.0%, and 33.3% of sand flies feeding on ear, mouth, and testicular lesions
74 cales provide the best fit with experimental sand fly feeding data, pointing to the importance of the
75 r organisms, <4% were identical to described sand fly genes, and 42% had no match to any database seq
76                                              Sand fly gut populations of both L. mexicana and L. infa
77        The Leishmania protozoa reside in the sand fly gut, but the nature of the immune response to t
78                                          The sand flies have adapted to various ecological niches in
79 following transmission to the skin by vector sand flies have been difficult to examine directly.
80                           To investigate the sand fly immune response and its interaction with the Le
81 have demonstrated that the activation of the sand fly immune system, via depletion of a single gene,
82                             The abundance of sand flies in IRS and non-IRS villages was significantly
83 s and enterobacteria, both are shared in the sand flies in the two regions.
84 ngs suggest that the ecological diversity of sand fly in Sichuan and Henan may contribute to shaping
85                                       During sand fly infections by the protozoan parasite Leishmania
86                                              Sand flies inject saliva while feeding in the vertebrate
87 ment site inside the alimentary tract of the sand fly insect vector.
88                                   Leishmania-sand fly interactions are reviewed in the context of the
89              This review looks at Leishmania-sand fly interactions as the parasites develop from amas
90 phoglycan-containing molecules in Leishmania-sand fly interactions were tested by using mutants speci
91 sed sugars of its LPG to manipulate parasite-sand fly interactions.
92 nfected mice to transmit parasites to vector sand flies, it was observed that following low-dose chal
93 udied plant feeding of Lutzomyia longipalpis sand flies, known vectors of Leishmania infantum/chagasi
94 fter transmission through the bite of female sand flies, Leishmania spp. can cause a broad spectrum o
95 ant for sand fly ecological adaptability and sand fly-Leishmania genetic co-variation could be helpfu
96                          Female phlebotomine sand flies Lutzomyia longipalpis naturally harbor popula
97 ries constructed from midgut tissue from the sand fly Lutzomyia longipalpis and analyzed the transcri
98  that salivary gland lysate of the New World sand fly Lutzomyia longipalpis markedly enhanced L. majo
99 istributed hematophagous insect vectors, the sand fly Lutzomyia longipalpis s.l., the mosquitoes Anop
100 n with Leishmania major is enhanced when the sand fly Lutzomyia longipalpis salivary peptide maxadila
101  isolated from salivary gland lysates of the sand fly Lutzomyia longipalpis, a vector of leishmaniasi
102 LJM11, an abundant salivary protein from the sand fly Lutzomyia longipalpis, belongs to the insect "y
103 nformation of the transcripts present in the sand fly Lutzomyia longipalpis.
104 lly isolated from the salivary glands of the sand fly Lutzomyia longipalpis.
105 th the distribution of its known vector, the sand fly Lutzomyia verrucarum.
106 e of leishmaniasis, a disease transmitted by sand fly (Lutzomyia longipalpis) bites.
107 w that the concentration of ROS increased in sand fly midguts after they fed on the insect pathogen S
108 gotes and procyclic LPG were able to bind to sand fly midguts in vitro whereas metacyclic parasites a
109 at Leishmania are transmitted exclusively by sand flies, none of the experimental models of leishmani
110  are transmitted exclusively by phlebotomine sand flies of the genera Phlebotomus and Lutzomyia.
111                                              Sand fly Phlebotomus chinensis is a primary vector of tr
112  In this article, we investigate whether the sand fly Phlebotomus papatasi, known to produce a strong
113 asite transmitted in nature by the Old World sand fly Phlebotomus papatasi.
114  shown for the first time in the wild-caught sand fly populations of Turkey.
115 e that prior exposure to bites of uninfected sand flies potentiates their ability to transmit infecti
116 e where it was discovered, was isolated from sand flies (Psathyromyia abonnenci, formerly Lutzomyia a
117 he blood or skin as a source of infection to sand flies remains unclear, and the possible effect of m
118  demonstrates a differential response of the sand fly ROS system to gut microbiota, an insect pathoge
119  fly or by silencing a gene that expresses a sand fly ROS-scavenging enzyme.
120 experiments demonstrate that pre-exposure to sand fly saliva confers protection against leishmaniasis
121       Together, these results imply that the sand fly saliva facilitates Leishmania evasion of the ho
122 mmune activation, oxidative stress, and anti-sand fly saliva IgG concentrations in dog sera with diff
123               A panel of biomarkers and anti-sand fly saliva IgG were measured in canine sera.
124 e describe the duration and nature of DTH to sand fly saliva in humans from an endemic area of Mali.
125                                  Immunity to sand fly saliva in rodents induces a T(H)1 delayed-type
126 od mononuclear cells (PBMCs) stimulated with sand fly saliva in vitro.
127                                              Sand fly saliva is known to enhance Leishmania infection
128 l needle challenge with Leishmania major and sand fly saliva when vaccinated intravenously.
129  the vertebrate host is also inoculated with sand fly saliva, which exerts powerful immunomodulatory
130   PBMCs from 98% of individuals responded to sand fly saliva.
131 functional genomics approach to identify the sand fly salivary components that are responsible for th
132 moglein 1 (Dsg1) cross-reacts with the LJM11 sand fly salivary gland Ag.
133  as a vaccine expression system for LJM11, a sand fly salivary protein identified as a good vaccine c
134 umulative evidence that immunity to specific sand fly salivary proteins confers a significant level o
135 rmal immunization of mice with 500 ng of the sand fly salivary recombinant protein LJM11 (rLJM11) fro
136 ases that degrade the stomodeal valve of the sand fly; secretion of a neuropeptide that arrests midgu
137                    Exposure to L. intermedia sand flies skews the human immune response, facilitating
138 laviviruses are rarely (if ever) vectored by sand fly species, at least in the Old World.
139                            The proportion of sand flies testing positive for DNA from a given plant f
140 of Leishmania within the alimentary canal of sand flies the parasites have to survive the hostile env
141 hroids, and susceptibility profile of Indian sand flies, the continued use of DDT in this IRS program
142 et of sequence data reported from a specific sand fly tissue and provides further information of the
143       Leishmania parasites need phlebotomine sand flies to complete their life cycle and to propagate
144 rotected against cutaneous disease following sand fly transmission of Leishmania major in susceptible
145          Employing i.d. inoculation to model sand fly transmission of parasites has significant conse
146 eishmania major (L.m.) parasites early after sand fly transmission or needle inoculation, but phagocy
147 against the potency of a Leishmania-infected sand fly transmission.
148 ocytic choriomeningitis virus (LCMV), or the sand fly-transmitted arbovirus Toscana virus (TOSV).
149                 Cutaneous leishmaniasis is a sand fly-transmitted disease characterized by skin ulcer
150 s the pathology and immunity associated with sand fly-transmitted infection.
151 d controlled protective immune response to a sand fly-transmitted Leishmania somewhat mimicking "leis
152 (LPG) implicated in parasite survival in the sand fly vector and the initial stages of establishment
153 ), and a decidedly peripatetic and adaptable sand fly vector are the primary forces.
154 ajor strains during their development in the sand fly vector has been experimentally shown.
155 omes infected with Leishmania major when the sand fly vector injects parasites into skin along with s
156                            The saliva of the sand fly vector of leishmaniasis significantly enhanced
157  that the infectiousness of patients for the sand fly vector of visceral leishmaniasis is linked to p
158 quence tag library has been generated from a sand fly vector of visceral leishmaniasis, Lutzomyia lon
159  the differentiation of parasites within the sand fly vector to the highly infective metacyclic proma
160                  Mating occurred only in the sand fly vector, and hybrids were transmitted to the mam
161                                     Its main sand fly vector, Lutzomyia longipalpis s.l.
162 hich were efficiently picked up by a natural sand fly vector, Phlebotomus sergenti.
163             During its life cycle within the sand fly vector, the parasite differentiates from a divi
164                            To survive in its sand fly vector, the trypanosomatid protozoan parasite L
165 ishmania spp. is transmitted to mammals by a sand fly vector.
166 l for parasite survival in the midgut of its sand fly vector.
167 y large skin lesions and is transmitted by a sand fly vector.
168 fter they are deposited into the dermis by a sand fly vector.
169 ccurs between Leishmania parasites and their sand fly vectors.
170 vertebrate macrophages and be transmitted by sand fly vectors.
171 ania parasites, and 4 contained phlebotomine sand fly vectors.
172 their ability to transmit L. major to vector sand flies was completely abrogated.
173                                         From sand flies, we isolated most of the known Phlebovirus st
174 tion of parasites by the bite of an infected sand fly, we identified differences in the preexisting a
175                                              Sand flies were collected from different towns (Karaburu
176                 After sterile washing steps, sand flies were dissected and guts were separated.
177                                              Sand flies were highly resistant to DDT but susceptible
178          Microbiome profiling of wild-caught sand flies will be of great help in the investigating of
179                    Finally, the treatment of sand flies with an exogenous ROS scavenger (uric acid) a
180 biota by pretreatment of Leishmania-infected sand flies with antibiotics or neutralizing the effect o
181                           The coevolution of sand flies with Leishmania species of mammals and lizard
182                                           In sand flies with mature Leishmania infections the anterio
183 ur after exposure to the bite of an infected sand fly, yet only one is under evaluation in humans.

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