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1 d long-chain base and a C24 monohydroxylated saturated fatty acid.
2 ed fatty acid fraction was higher than total saturated fatty acid.
3 e cashews exceed the disqualifying amount of saturated fatty acids.
4 lyzed for unsaturated fatty acids (UFAs) and saturated fatty acids.
5 ontained palmitic and stearic acids as major saturated fatty acids.
6 acids (n-3 and n-6), and the lower levels of saturated fatty acids.
7 id subspecies containing monounsaturated and saturated fatty acids.
8 ynthesis of monounsaturated fatty acids from saturated fatty acids.
9 overstimulation of the JNK1/c-Jun pathway by saturated fatty acids.
10 lum (ER) stress is elicited in beta-cells by saturated fatty acids.
11 patocyte sensitivity to cytotoxic effects of saturated fatty acids.
12 d unsaturated fatty acids for growth but not saturated fatty acids.
13 high levels of intracellular cholesterol and saturated fatty acids.
14 ceride biosynthesis increased sensitivity to saturated fatty acids.
15 egulation of fabA transcription by exogenous saturated fatty acids.
16 oprotein(a) in comparison with diets high in saturated fatty acids.
17 rimentally observed omega-1 hydroxylation of saturated fatty acids.
18 holesterol and also a much higher content of saturated fatty acids.
19 ynthesis of monounsaturated fatty acids from saturated fatty acids.
20 culture with monounsaturated fatty acids and saturated fatty acids.
21 le and beta-cells under conditions of excess saturated fatty acids.
22 composition toward lower proportions of all saturated fatty acids.
23 present that can preferentially preserve the saturated fatty acids.
24 ert a part of their dietary carbohydrates to saturated fatty acids.
25 ere observed only in adipocytes treated with saturated fatty acids.
26 sis and promotes the hepatic accumulation of saturated fatty acids.
27 ntration of the total and certain individual saturated fatty acids.
29 s1 (fab1) mutant has increased levels of the saturated fatty acid 16:0 due to decreased activity of 3
31 from our previous studies demonstrated that saturated fatty acids activate TLRs, whereas n-3 polyuns
33 ich in omega-3 fatty acids to a diet rich in saturated fatty acid affects the substrates for brain pl
35 y acid needs, including both unsaturated and saturated fatty acids, along with the 3-hydroxyl fatty a
36 synthetic PC species containing at least one saturated fatty acid also support the native conformatio
37 xposure of primary peritoneal macrophages to saturated fatty acids also alters iron metabolism gene e
38 ing pathway triggered by TLR4 recognition of saturated fatty acids, an event that is essential for li
39 ntent, total phenolic acids, gamma-oryzanol, saturated fatty acid and mono-unsaturated fatty acid of
40 both innate and adaptive immune responses by saturated fatty acid and n-3 polyunsaturated fatty acid
41 turated or trans fatty acids instead of high-saturated fatty acid and trans fatty acid or low-fat sna
42 effect that an atherogenic diet (AD) high in saturated fatty acids and cholesterol has on disease pro
43 strain had significantly elevated levels of saturated fatty acids and longer chain lengths than the
44 , odd-chain fatty acids, and very-long-chain saturated fatty acids and low concentrations of gamma-li
47 pes of dietary fat, and food sources rich in saturated fatty acids and the incidence of type 2 diabet
48 its membrane and storage lipids contain only saturated fatty acids and the monounsaturated products o
50 legumes, cereals, fish, monounsaturated and saturated fatty acids, and alcohol and constructed MeDi
51 ial set of fatty acids, highly enriched with saturated fatty acids, and caveolin-1 was acylated by pa
52 e; intakes of energy, trans fatty acids, and saturated fatty acids; and use of supplements, cardiovas
56 that saturated fatty acyl-CoAs, rather than saturated fatty acids, are high affinity PPAR alpha liga
57 We evaluated synthetic omega-3 epoxides of saturated fatty acids as antiproliferative and pro-apopt
58 l analyses, and the data indicate long chain saturated fatty acids as the biological substrates of th
59 We found that the fraction of CD36-dependent saturated fatty acid association/absorption in these mod
60 o cultured cells by showing that exposure to saturated fatty acids at concentrations that lead to end
61 eered yeast lipid comprises EPA at 56.6% and saturated fatty acids at less than 5% by weight, which a
62 aberrant generation of bioactive lipids when saturated fatty acid availability to tissues is increase
63 higher delta(18)O, delta(2)H, linoleic acid, saturated fatty acids beta-sitosterol, sn-1 and 3 diglyc
64 in fat absorption, especially of long-chain saturated fatty acids, but pancreatic triglyceride lipas
65 ice fed a high-fat diet, increased uptake of saturated fatty acids by the osteoblast accelerates the
67 erminal alkenes are produced from a range of saturated fatty acids (C12-C20), and stopped-flow spectr
69 dation of tyrosinase, whereas palmitic acid (saturated fatty acid, C16:0) retarded the proteolysis.
70 , these two co-products are rich in long and saturated fatty acids (C22:0-C24:0), contain cholesterol
71 idence that palmitic acid, the major dietary saturated fatty acid, can directly activate TLR has not
72 of them (>90%) were totally esterified with saturated fatty acids (capric, lauric, myristic, palmiti
73 ation by demonstrating that the much shorter saturated fatty acid, caprylate, has no significant effe
76 meat also contributes to the intake of fat, saturated fatty acids, cholesterol, and other substances
78 curred within the upper physiologic range of saturated fatty acid concentrations in vivo, suggesting
79 1.0 vs 41.4 +/- 0.3), together with a lower saturated fatty acid content (33.5 +/- 0.5 vs 47.3 +/- 0
80 found that TMX-treated livers have increased saturated fatty acid content despite changes in gene exp
82 whole adult animals, show an increase in the saturated fatty acid content of several phospholipid spe
85 on of alkanes, alcohols, organic acids and n-saturated fatty acids coupled to sulfate reduction and t
87 arkedly reduced hepatic steatosis, increased saturated fatty acids, decreased acetyl-CoA carboxylase
88 hown that a diet with high levels of dietary saturated fatty acids decreases survival in septic mice,
89 s increased when cells are supplemented with saturated fatty acids, demonstrating the physiological r
90 tion and insulin resistance, suggesting that saturated fatty acids derived from the high-fat diet act
92 ferase long chain (Sptlc)-2, is required for saturated fatty acid-driven Nlrp3 inflammasome activatio
93 fatty acids), but not weak affinity ligands (saturated fatty acids), elicited conformational changes
94 Prolonged ingestion of a cholesterol- or saturated fatty acid-enriched diet induces chronic, ofte
95 preferential uptake into lipid storage while saturated fatty acid exhibits toxicity in hepatic cells.
97 Here we show that high fat diet (HFD) or saturated fatty acid exposure directly activates CCAAT/e
99 reinhardtii cells deprived of iron have more saturated fatty acid (FA), possibly due to the loss of f
101 ) macrophages showed an increased content of saturated fatty acids (FAs) and decreased omega-3 FAs (e
102 an HF diet rich in either monounsaturated or saturated fatty acids (FAs) and of exercise on EE and ch
104 yl reductase, which diverts intermediates to saturated fatty acid formation, in contrast to E. coli w
107 catalyze the deacylation of the amide-linked saturated fatty acid from ceramide to generate sphingosi
108 Higher total fat (>25-30% of energy), saturated fatty acids (>13% of energy), and monounsatura
109 or acute intracerebroventricular infusion of saturated fatty acid had less palmitoylated LMO4, less o
112 R influences the effect of substituting high-saturated fatty acid (HSFA) diets by isoenergetic altera
114 The DeltaplsX strain contained longer chain saturated fatty acids imparting a distinctly altered pho
117 lacement of TFA with STA compared with other saturated fatty acids in foods that require solid fats b
119 of lipin-2 in the proinflammatory action of saturated fatty acids in murine and human macrophages.
120 hat SCD1 inhibition promoted accumulation of saturated fatty acids in plasma and tissues and reduced
121 ty acids (MUFAs) or a high ratio of MUFAs to saturated fatty acids in plasma, reflecting a high activ
122 Dietary approaches to restore levels of saturated fatty acids in the intestine might reduce etha
125 cause of this specificity, the occurrence of saturated fatty acids in the TAG sn-2 position is infreq
131 SIS) in a PKA-dependent manner and prevented saturated fatty acid-induced apoptosis in human and rat
132 an upstream signaling component required for saturated fatty acid-induced ceramide biosynthesis.
133 diets with similar calcium contents affect a saturated fatty acid-induced increase in blood lipids di
134 iet, milk- and cheese-based diets attenuated saturated fatty acid-induced increases in total and LDL
136 indings identify pannexins as new targets of saturated fatty acid-induced inflammation in myotubes, a
137 association between sleep duration and lower saturated fatty acid intake in younger (aged 20-64 y) ad
139 neonatal exposure to a maternal diet rich in saturated fatty acids is associated with altered activit
140 idopsis results in a two-thirds reduction in saturated fatty acids, largely palmitate, in the leaf ex
141 Here, we report for the first time that the saturated fatty acid lauric acid induced dimerization an
143 presented in this study demonstrate that the saturated fatty acid, lauric acid, up-regulates the expr
144 posure included the following: (i) decreased saturated fatty acids levels, (ii) retention of unsatura
147 olyunsaturated fatty acids predominated over saturated fatty acids, mainly due to the contribution of
148 t the depth and duration of deep torpor, and saturated fatty acids may be preferentially used during
149 gest that a higher consumption of long-chain saturated fatty acids may enhance the risk of gallstone
151 ts that high intake of total fat and certain saturated fatty acids may worsen prostate cancer surviva
152 mentation with whey protein and medium-chain saturated fatty acids (MC-SFAs) improved postprandial li
153 was used for quantification of medium chain saturated fatty acids (MCSFAs) and the results revealed
154 SIMS) was used to measure the diffusivity of saturated fatty acid molecules from a fingerprint on a s
155 T) catalyses the attachment of the 14-carbon saturated fatty acid, myristate, to the amino-terminal g
159 umption of specific and different classes of saturated fatty acids on the risk of gallstone disease i
160 thioester-linked modification of a 16-carbon saturated fatty acid onto the cysteine residue of a prot
163 t cancer risk (621 cases): caprate (10:0), a saturated fatty acid (OR: 1.77; 95% CI = 1.28, 2.43); ga
164 the highest quartile of intake of total fat, saturated fatty acids, or monounsaturated fatty acids ha
166 the rumenic acid (P < 0.01), and reduced the saturated fatty acids (P < 0.01) and the n-6/n-3 PUFA ra
167 demonstrated an increase in TFAs (p<0.001), saturated fatty acids (p<0.001) and decrease in cis-unsa
168 acrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-
169 n primary macrophages exposed to the dietary saturated fatty acid palmitate in combination with LPS.
170 expression is induced in macrophages by the saturated fatty acid palmitate, acts via its receptor Un
175 docosahexaenoic acid (DHA), relative to the saturated fatty acid palmitic acid (PA), on the hepatic
176 We now demonstrate that treatment with the saturated fatty acid palmitic acid results in sustained
178 inoleic, oleic and elaidic acids) as well as saturated fatty acids (palmitic and stearic acids) in al
179 ore, treatment of rat 3T3-L1 adipocytes with saturated fatty acids (palmitic or stearic acids) in the
180 Caco-2/TC7 enterocytes were treated with the saturated fatty acid, palmitic acid, the insulin-signali
181 hromatography/mass spectrometry identified 2 saturated fatty acids, palmitic acid methyl ester (PAME)
182 cGlcDAG provided that PE or PC contained one saturated fatty acid) paralleled the results observed pr
183 ence of the two factors: ripeness influenced saturated fatty acids, pigment content and deacetoxy ole
184 of the Healthy Diet Indicator (HDI) included saturated fatty acids, polyunsaturated fatty acids, mono
185 acids, alpha-linolenic acid, linoleic acid, saturated fatty acids, polyunsaturated fatty acids, omeg
187 , glucosamine, or amino acids had no effect, saturated fatty acids potently reduced PGC-1alpha and -b
188 mmary, the leaf cell responds to the loss of saturated fatty acid production in the fatb-ko mutant by
189 ercial yarrow have higher content of fat and saturated fatty acids, proteins, ash, energy value, suga
193 r knowledge, no studies have evaluated a low-saturated fatty acid (SFA) (<7% calories) diet that cont
194 showed that palmitic acid-the most abundant saturated fatty acid (SFA) and the major SFA in the HFD
195 comparison between extreme quintiles, higher saturated fatty acid (SFA) and trans-fat intakes were as
198 UFA), polyunsaturated fatty acid (PUFA), and saturated fatty acid (SFA) in the breast adipose tissue.
201 disease (CVD) risk involve reducing dietary saturated fatty acid (SFA) intake to </=10% of total ene
202 d dysfunction have been shown to depend upon saturated fatty acid (SFA) oversupply and de novo sphing
203 tic triglyceride monounsaturated acid (MUFA)/saturated fatty acid (SFA) ratio despite induction of th
204 ion and polyunsaturated fatty acid (PUFA) to saturated fatty acid (SFA) ratio were higher and C18:2n-
205 otal cholesterol (TC), amplified response to saturated fatty acid (SFA) reduction, and increased card
206 ed that metabolism of palmitate, a prevalent saturated fatty acid (SFA), could drive solid-like domai
207 of various types of fatty acids, especially saturated fatty acid (SFA), on cardiovascular disease (C
209 ilk sold in the summer contained lower total saturated fatty acid (SFA; 67 vs 72 g/100g fatty acids)
210 polyunsaturated (PUFA) fatty acids and lower saturated fatty acids (SFA) than those from pigs raised
211 e role of lipid-modifying enzymes converting saturated fatty acids (SFA) to monounsaturated fatty aci
213 d in cell culture by exposing macrophages to saturated fatty acids (SFA), and endoplasmic reticulum (
214 ignificantly increased the concentrations of saturated fatty acids (SFA), mono-unsaturated fatty acid
215 calibrations were developed and proposed for Saturated Fatty Acids (SFA), Monounsatured Fatty Acids (
217 ng the association between intake of dietary saturated fatty acids (SFAs) and cardiovascular disease
218 carcinogenesis, and blood levels of specific saturated fatty acids (SFAs) and monounsaturated fatty a
219 affects insulin homeostasis via synthesis of saturated fatty acids (SFAs) and monounsaturated fatty a
220 ither monounsaturated fatty acids (MUFAs) or saturated fatty acids (SFAs) and their impact on glucose
229 ata support the benefits of reducing dietary saturated fatty acids (SFAs) on insulin resistance (IR)
230 tion and body composition during overfeeding saturated fatty acids (SFAs) or polyunsaturated fatty ac
232 cute elevation of NEFAs enriched with either saturated fatty acids (SFAs) or SFAs with long-chain (LC
236 iscuss macronutrient replacement options for saturated fatty acids (SFAs) to optimize cardiovascular
237 s generally recommend reducing the intake of saturated fatty acids (SFAs) to reduce coronary artery d
238 rcise, but the effects of the replacement of saturated fatty acids (SFAs) with monounsaturated fatty
240 l diet with no pistachios [25% total fat; 8% saturated fatty acids (SFAs), 9% monounsaturated fatty a
241 rse genetics, revealed that NoDGAT2A prefers saturated fatty acids (SFAs), NoDGAT2D prefers monounsat
242 haracteristic of the Western diet, including saturated fatty acids (SFAs), omega-3 (n-3) fatty acids,
243 three high-fat (HF, 60% kcal) diets rich in saturated fatty acids (SFAs), omega-6 or omega-3 polyuns
244 ed total carbohydrate (grams per day), total saturated fatty acids (SFAs), percentage of energy from
247 the AAD [designed to contain 38% fat and 14% saturated fatty acids (SFAs)], the Step I diet (30% fat
248 plant proteins, and ratio of unsaturated to saturated fatty acids, showed significant inverse associ
249 ecular weight and carbon preference index of saturated fatty acids significantly decreased within fin
250 two-thirds was either soybean oil (SO), low-saturated fatty acid soybean oil (LoSFA-SO), high-oleic
253 At the molecular level, these events involve saturated fatty acid stimulation of the adenine nucleoti
255 ctic factors after exposure of adipocytes to saturated fatty acids, such as palmitate, occurs via tra
256 ttenuated SREBP activity maintain long-chain saturated fatty acid synthesis, while losing fatty acid
257 that hfRPE cells can metabolize palmitate, a saturated fatty acid that constitutes .15% of all lipids
258 n-2 in proinflammatory signaling mediated by saturated fatty acids that occurs concomitant with an en
259 eramide (CM) from ROS contained PUFAs but no saturated fatty acids; the converse was true of CM from
260 ecommendations, should the steps to decrease saturated fatty acids to as low as agriculturally possib
261 trachomatis that selectively scavenges host saturated fatty acids to be used for the de novo synthes
262 demonstrated as a shift from primarily C16:0 saturated fatty acids to C16:1 monounsaturated fatty aci
263 We determined whether lowering the ratio of saturated fatty acids to monounsaturated fatty acids in
264 the Calvin cycle to the de novo synthesis of saturated fatty acids to replace polyunsaturated ones in
265 Their synthesis depends on the conversion of saturated fatty acids to unsaturated fatty acids by Delt
266 , the transfer of myristic acid (a 14-carbon saturated fatty acid) to an N-terminal glycine catalyzed
268 predict polyunsaturated, monounsaturated and saturated fatty acids, together with triacylglycerides,
270 ligands provides a mechanism accounting for saturated fatty acid transactivation in cell-based assay
271 een implicated, the exact mechanisms whereby saturated fatty acids trigger beta-cell death remain elu
275 is required for the synthesis of C28 and C30 saturated fatty acids (VLC-FA) and of C28-C38 very long
285 erols and sphingolipids with very long chain saturated fatty acids when compared with the bulk of the
287 packed with cholesterol, sphingomyelin, and saturated fatty acids, whereas disordered domains contai
288 Deletion of SCT1 decreases the content of saturated fatty acids, whereas overexpression of SCT1 dr
289 , PERPP is suppressed by antioxidants and by saturated fatty acids, which are not susceptible to lipi
290 nd other phospholipids were also enriched in saturated fatty acids, which could reflect limited acyl
291 ts as the result of increased levels of free saturated fatty acids, which promote insulin receptor ub
292 lammation and elevated levels of circulating saturated fatty acids, which trigger inflammatory respon
293 milk that contains excessive long chain and saturated fatty acids, which triggers ceramide accumulat
294 uivalents as FADH2 through beta-oxidation of saturated fatty acids, while COD:N of 11:1 do it through
295 ent and T2D (P-trend = 0.24), but intakes of saturated fatty acids with 4-10 carbons, lauric acid (12
297 een TLR4-mediated inflammatory signaling and saturated fatty acids with regard to ceramide generation
298 saturated fatty acids), or milk fat (rich in saturated fatty acids) with or without fish oil (rich in
299 is of retinal NSLs indicated an abundance of saturated fatty acids, with the presence of VLC-FAs but
300 eness of different cell types and tissues to saturated fatty acids would depend on the expression of
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