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1 drug delivery combined with transient vessel scaffolding.
2 ion of laminin trimers and basement membrane scaffolding.
3 lished findings and a refined model of IQGAP scaffolding.
4 in compared to control mice that received no scaffolding.
5 desensitization is directed by PKA via AKAP scaffolding.
6 omosome conformation capture data for genome scaffolding.
7 hanisms, including sporadic mutations in its scaffolding A and regulatory B subunits or more frequent
8 ind that ARPP-16 interacts directly with the scaffolding A subunit of the serine/threonine protein ph
9 ugh epigenetic modifications of postsynaptic scaffolding A-kinase anchoring protein 79/150 (AKAP79/15
10 ntains a catalytic (C) subunit, a structural/scaffolding (A) subunit, and a regulatory (B) subunit.
13 urther suggest co-targeting of enzymatic and scaffolding activities within Ras-MAPK signalling comple
15 tailored torques to specific environments by scaffolding alternative stator placement and number.
17 esults indicate that the respective roles of scaffolding and coat proteins may have been redistribute
18 potentiates sequence assembly of genomes via scaffolding and comparisons that globally validate or co
19 read sequencing technology by assisting with scaffolding and detecting large and complex structural v
20 which CAV1 phosphorylation facilitates CAV1 scaffolding and GRK2-CAV1 interaction, thus clustering e
21 -forming connexin proteins and also multiple scaffolding and regulatory protein components, which wer
22 g the kinase arm, PI3Kgamma inhibits PP2A by scaffolding and sequestering, playing a key parallel syn
28 eir conserved reticulon homology domain, and scaffolding, arising from the ability of RTNs to form lo
29 Rab3-interacting molecules (RIMs) provide scaffolding at presynaptic active zones and are involved
30 a previously unnoticed link between membrane scaffolding by endoA2 and pulling-force-driven dynamic s
31 n, short reads for consensus validation, and scaffolding by optical and chromatin interaction mapping
32 epair systems and components, e.g. potential scaffolding cofactors (Rot/TROVE and SPFH/Band-7 modules
34 heterotypic association is used to assemble scaffolding complexes with distinct binding properties a
40 ner of Sirt1, as shown by the binding of the scaffolding domain of caveolin-1 (amino acids 82-101) to
43 blocked CAV1 phosphorylation induced by CAV1 scaffolding domain, indicating that CAV1 interaction wit
46 the Hsp70 co-chaperone, BAG3, is a modular, scaffolding factor to bring together sHsps and Hsp70s.
48 ected by the giant protein titin, which is a scaffolding filament, signaling platform, and provider o
49 onomic details of diversity are an essential scaffolding for biology education, yet outdated methods
50 extracellular matrix (ECM) provides physical scaffolding for cellular constituents and initiates bioc
51 f coordinated activities between wedging and scaffolding for endophilin to produce stable membrane tu
52 t this topographic organization provides the scaffolding for the subsequent development of visual cor
53 a, we discuss the insights obtained from the scaffolding function and how this non-canonical role cou
54 Our findings support a kinase-independent scaffolding function of CK2alpha that promotes resistanc
55 dence from recent studies implicate that the scaffolding function of enzymes could be as important in
56 osphorylation, we have demonstrated that the scaffolding function of receptor interacting protein kin
57 RAC1/PAK1 and promoted a kinase-independent scaffolding function that led to recruitment and phospho
58 suppressor homologs 1/2 (LATS1/2), uses its scaffolding function to link MST1/2 with MARK3, and inhi
59 isoforms are emerging with localizations and scaffolding functions at sites away from the NE, suggest
60 hese findings, we propose that Brc1 provides scaffolding functions linking gammaH2A, Rhp18, and Smc5/
61 pletion suggest that OGT's glycosylation and scaffolding functions play distinct roles in the replica
66 trates an unexpected level of autoregulatory scaffolding in mammalian stress-activated MAP kinase sig
68 hly resolved assembly graphs with long-range scaffolding information promises the complete and automa
69 d to calculate the effective kon and koff of scaffolding interactions such as those that immobilize r
70 nases is kept at a minimum in the absence of scaffolding interactions, which position the enzymes for
72 otic genomes; however, at present additional scaffolding is needed to achieve chromosome-level assemb
73 ury (SCI), we demonstrated that the tailored scaffolding maintained hMSC stemness, engraftment, and l
74 ombining the programming ability of DNA as a scaffolding material with a one-step lithographic proces
76 e observations elevate the importance of the scaffolding mechanism, rather than H0 insertion, for the
78 in SZ cohorts is the duplication of Synaptic Scaffolding Molecule (S-SCAM, also called MAGI-2), which
79 , a gene encoding a protein kinase A-binding scaffolding molecule, were significantly associated with
86 truct a highly accurate de novo assembly and scaffolding of a human genome with scaffold N50 of 20 Mb
88 atal experiences may shape the somatosensory scaffolding of later perceptual, cognitive, and social d
92 -eluting stents, while providing a transient scaffolding of the vessel to prevent acute vessel closur
93 non-canonical role of class IIa HDACs in the scaffolding of transcriptional regulatory complexes, whi
95 eins, Ras guanine exchange factors, kinases, scaffolding or adaptor proteins, ubiquitin ligases, phos
98 Multisensory processes are fundamental in scaffolding perception, cognition, learning, and behavio
100 uitination, which markedly modifies PSD-95's scaffolding potentials, enables its synaptic targeting,
101 euse theory, empirical tests of the related "scaffolding" principle of abstract concept development s
103 provide a novel mechanism that exploits the scaffolding properties of the N terminus of p120RasGAP t
104 and show that CpmB competes with the 80alpha scaffolding protein (SP) for a binding site on the capsi
107 d G protein-coupled receptors coupled by the scaffolding protein A-kinase-anchoring protein (AKAP)79/
108 During varphiX174 assembly, the external scaffolding protein acts like a coat protein, self-assoc
111 smaller than a Golgi subdomain positive for scaffolding protein AKAP450, which is thought to recruit
113 ite for the dynamic functions of IQGAP1 as a scaffolding protein and a critical mechanism in temporal
114 apsid') built by multiple copies of coat and scaffolding protein and by one dodecameric portal protei
115 dditionally, we explored the function of the scaffolding protein and main component of caveolae, cave
120 at appears to contain substantial amounts of scaffolding protein as well as DNA, suggesting that DNA
121 ule dynamics at both locations, but how this scaffolding protein assembles microtubule nucleation mac
122 ne-associated guanylate kinase, is the major scaffolding protein at excitatory postsynaptic densities
124 bstitutions ranged from inefficient internal scaffolding protein B binding to faulty procapsid elonga
126 a interaction protein (GSKIP) is a cytosolic scaffolding protein binding protein kinase A (PKA) and g
128 called MAGI-2), which encodes a postsynaptic scaffolding protein controlling synaptic AMPA receptor l
130 74 morphogenesis, 240 copies of the external scaffolding protein D organize 12 pentameric assembly in
131 assembly intermediates, whereas the external scaffolding protein D organizes 12 of these intermediate
133 neuromuscular junction (NMJ), the endocytic scaffolding protein Dap160 colocalizes during the SV cyc
134 -CDF) of CaV1.3 channels that depends on the scaffolding protein densin and CaMKII and that outlasts
135 orted interaction among CaV1.3 channels, the scaffolding protein densin, and CaMKII could generate a
136 HTT forms a ternary protein complex with the scaffolding protein DISC1 and cAMP-degrading phosphodies
141 tein likely acting as a dynamic cell surface scaffolding protein for the assembly of different signal
142 basolateral amygdala, the clustering of the scaffolding protein Gephyrin and of gamma-aminobutyric a
143 otein collybistin (CB) recruits the receptor-scaffolding protein gephyrin to mammalian inhibitory gly
144 ere we show that the conserved signaling and scaffolding protein Girdin localizes to the proximal reg
149 rtant new insights into the role of FAK as a scaffolding protein in molecular complexes that regulate
150 omplementation group A (XPA) is an essential scaffolding protein in the multiprotein nucleotide excis
154 STATEMENT: Integrin-linked kinase (ILK) is a scaffolding protein involved in integrating signals from
155 ozygous mutations in CARD11, which encodes a scaffolding protein involved in lymphocyte receptor sign
156 1; also known as p62) encodes a multidomain scaffolding protein involved in various key cellular pro
157 our capsids, aided by the discovery that the scaffolding protein is exceptionally prone to radiation-
160 es, MAP17 is known to interact with PDZK1, a scaffolding protein linked to other transporters, includ
161 also called AKAP450/CG-NAP/AKAP9) is a large scaffolding protein located at both the centrosome and G
162 Here, we show that loss of function of a scaffolding protein Mask, also known as ANKHD1 (Ankyrin
163 sis of human metastatic genes identified the scaffolding protein metastasis suppressor 1 (MTSS1) as a
164 Mutations in NBEAL2, the gene encoding the scaffolding protein Nbeal2, are causal of gray platelet
165 nsically disordered tail of the multi-domain scaffolding protein NHERF1, which affects the intracellu
166 milar to mice overexpressing PSD-95, a major scaffolding protein of postsynaptic density involved in
167 Disrupted in Schizophrenia 1 (DISC1) is a scaffolding protein of significant importance for neurod
168 teins BAZ2A and BAZ2B constitute the central scaffolding protein of the nucleolar remodeling complex
172 lation of GluN2B Y1472, whereas the synaptic scaffolding protein postsynaptic density protein 95 (PSD
173 s a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors
174 where it associates with and stabilizes the scaffolding protein PSD95, promoting dendritic spine mat
177 ogene required for development, and DCAF7, a scaffolding protein required for craniofacial developmen
178 with poor patient prognosis, and BRPF1 is a scaffolding protein required for the assembly of histone
179 me through direct interaction with the large scaffolding protein RPN2 within the 19S regulatory parti
180 roteins 1 and 2 and with the multifunctional scaffolding protein sequestosome-1 (SQSTM1/p62) confirme
183 ises the NAD-dependent deacetylase Sir2, the scaffolding protein Sir4, and the nucleosome-binding pro
186 rrent study, we identify the multifunctional scaffolding protein spinophilin as a novel Group I mGluR
187 cultured astrocytes, suggesting that the DLG scaffolding protein stabilizes EAAT2b at the surface.
189 y reported that the immunophilin FKBP51 is a scaffolding protein that can enhance PHLPP-AKT interacti
190 ation of the Mdm2 pathway degrades PSD-95, a scaffolding protein that clusters NMDARs at the synapse
191 s sigma-1 receptor) is a unique chaperone or scaffolding protein that contributes to cellular protein
192 signaling is negatively regulated by Axin, a scaffolding protein that controls a rate-limiting step i
194 chizophrenia 1 (DISC1) is a multi-functional scaffolding protein that has been associated with neurop
197 Zonula occludens-1 (ZO-1) is a submembrane scaffolding protein that may display proinvasive functio
199 ptic density 95 (PSD-95) is a major synaptic scaffolding protein that plays a key role in bidirection
200 cells by knocking down ANLN, a cytoskeletal scaffolding protein that regulates cytokinesis and might
201 associated with its binding partner Homer, a scaffolding protein that regulates mGlu5 localization to
202 exclusively to wag31, a gene that encodes a scaffolding protein thought to orchestrate cell elongati
203 t RA T cells abundantly express the podosome scaffolding protein TKS5, which enables them to form tis
205 igher-order protein complexes containing K-H scaffolding protein to gain insight into its cellular fu
206 mplex comprising DNA ligase IIIalpha and the scaffolding protein X-ray repair cross-complementing pro
207 ng of DNA from the histone octamer; that the scaffolding protein XRCC1 enhances the ligation; that th
208 9 (AC9) is found tightly associated with the scaffolding protein Yotiao and the IKs ion channel in he
209 y a novel functional complex of the junction scaffolding protein ZO-1 and the F-BAR-domain protein TO
210 nding of CCCTC-binding factor, a chromosomal scaffolding protein, and increases histone and DNA methy
211 r components of the node is the cytoskeletal scaffolding protein, ankyrin G (AnkG), which interacts w
212 multiple ankyrin repeat domains 3 (SHANK3B) scaffolding protein, defective expression of which has b
213 ighly conserved double-PDZ domain-containing scaffolding protein, is robustly expressed in human-deri
214 which otoferlin acts as a calcium-sensitive scaffolding protein, localizing SNARE proteins proximal
215 rangement of the coat protein and release of scaffolding protein, resulting in dramatic procapsid lat
216 nhibitor, pointed to a mechanism involving a scaffolding protein, Wag31, involved in polar elongation
224 guanylate kinase (MAGUK) family of synaptic scaffolding proteins anchor glutamate receptors at CNS s
225 ion, we observed marked loss of postsynaptic scaffolding proteins and reduced complexity of the sub-s
226 as associated with reduced recruitment of TZ scaffolding proteins and reduced Smoothened levels at ci
228 taining for PSD-95 and gephyrin postsynaptic scaffolding proteins as proxies for excitatory and inhib
230 nalling domain interacts with the chemotaxis scaffolding proteins CheV and CheW, and comparative geno
231 eodomain finger-containing (BRPF) family are scaffolding proteins important for the recruitment of hi
232 domain and PHD finger-containing) family are scaffolding proteins important for the recruitment of hi
235 guanylate kinase (MAGUK) family of synaptic scaffolding proteins is critical for localization of glu
236 ts suggest that enzyme sequestration through scaffolding proteins is exploited by evolution to genera
237 DZ-binding motif allowing for binding of the scaffolding proteins Na(+)/H(+) exchanger regulatory fac
238 MAGUK (membrane-associated guanylate kinase) scaffolding proteins or NMDA receptors, it is necessary
241 m increase in the expression of the synaptic scaffolding proteins PSD-95 and SAP90/PSD-95-associated
244 isoform was recruited to nascent AZs by the scaffolding proteins Syd-1 and Liprin-alpha, and Unc13A
245 ) exchanger regulatory factor (NHERF) family scaffolding proteins that are required for many aspects
247 regulatory proteins (TARPs) are a family of scaffolding proteins that regulate AMPA receptor traffic
248 4-3-3 proteins, a family of highly conserved scaffolding proteins ubiquitously expressed in all eukar
249 al cellulosome assembly, including conserved scaffolding proteins unique to the Neocallimastigomycota
250 se disorders are those encoding postsynaptic scaffolding proteins with roles in synaptic transmission
251 ins constitute a highly conserved network of scaffolding proteins, adaptors and enzymes that form and
252 olytic metabolon is dependent on presynaptic scaffolding proteins, and disruption of the glycolytic m
254 es, including transcription factors, adaptor/scaffolding proteins, and uncharacterized proteins.
255 ned with RNA-induced phase separation of key scaffolding proteins, may be a general mechanism for con
257 ignal through Gi/o-coupled G-proteins and/or scaffolding proteins, such as beta-arrestin, we find tha
258 hogen effectors by partnering with different scaffolding proteins, which can each recognize distinct
265 s enriched in sphingolipids, cholesterol and scaffolding proteins; they serve as a platform for signa
266 deficiency of Shank3 can impair mGluR5-Homer scaffolding, resulting in cortico-striatal circuit abnor
270 psids are empty, B capsids retain a shrunken scaffolding shell, and C capsids-which develop into infe
272 oassembly of the surface shell with an inner scaffolding shell; then the procapsid matures via a majo
273 ts indicated that impaired AKAP-mediated PKA scaffolding significantly reduces DOR-GRK2 association a
275 shed yet constantly evolving multifunctional scaffolding strategies as well as in the emerging on-dem
276 ripotent stem cells, which bioengineering or scaffolding strategies have the most potential for kidne
279 cleation, serving as an excellent biomimetic scaffolding strategy to rebuild natural bone integrity.
282 ort the biological importance of PSMD12 as a scaffolding subunit in proteasome function during develo
283 NF-kappaB essential modulator (NEMO) is the scaffolding subunit of the inhibitor of kappaB kinase (I
284 -binding protein), whose binding to eIF4G (a scaffolding subunit) and eIF4A (an ATP-dependent RNA hel
287 ilaments thus serve an important function in scaffolding the axon/myelin-unit, evidently a late stage
290 nsic role that developmental vision plays in scaffolding the neural implementation of touch perceptio
292 ilin are thought to bend lipid membranes via scaffolding (the molding of membranes through the cresce
293 on laser lithography is employed for LC cell scaffolding to accurately verify theoretical predictions
295 iable vocal behavior of human infants is the scaffolding upon which speech and social interactions de
298 ough several different mechanisms, including scaffolding, wedging, oligomerization, and crowding.
299 it of the COPII coat contributes to membrane scaffolding, which enforces curvature on the nascent ves
300 These networks are built upon a structural scaffolding with intrinsic neuroplasticity that changes
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