ライフサイエンスコーパス: scale up

1 , increased safety profile, and potential to scale up.

2 d is costly, poorly reproducible and hard to scale up.

3 ed fabrications, high cost, and inability to scale up.

4 isting delivery platforms for feasibility of scale-up.

5 ction times, high concentrations, and facile scale-up.

6 reproducibility, bioprocess optimization and scale-up.

7 clinical trials have challenged programmatic scale-up.

8 tion in confined volumes and possible future scale-up.

9 avert 5.3 million infections relative to no scale-up.

10 that determine the potential for industrial scale-up.

11 ovide evidence for effective replication and scale-up.

12 it difficult to pinpoint a goal for surgical scale-up.

13 person, respectively, by the final years of scale-up.

14 T aerogel formation, thus limiting effective scale-up.

15 important causes of health burden need to be scaled up.

16 trol markedly increased as the programme was scaled up.

17 lure of the interventions to be developed or scaled up.

18 m gold catalysis is quite general and can be scaled up.

19 overcoming barriers to implementation and to scaling up.

20 regulated synaptic AMPAR accumulation during scaling up.

21 limitations and bottlenecks associated with scaling up.

22 ered by low productivity and difficulties in scaling up.

23 erature range (-78 degrees C to ambient) and scale up (10 g), while the chiral catalyst can be reused

24 d MMC (2004-2007), and during mature program scale-up (2007-2013).

25 nstrumentation, and cell designs involved in scaling up a benchtop experiment to an industrial-scale

26 stigating the cost and cost-effectiveness of scaling up a STH MDA programme targeting Ascaris lumbric

27 r people on ART, and efforts are underway to scale up access in resource-limited settings.

28 Scaling up access to HIV viral load testing for individu

29 with primary care providers is essential to scaling-up AIT provision in Europe, but to achieve this,

30 Scaling up all interventions in these packages from cove

31 es associated with cost, infrastructure, and scale up also need investigating.

32 Over lifetime, PrEP scale-up among 20- to 29-year-old women was very cost-ef

33 e to certain substrates and are difficult to scale up and implement on curved surfaces.

34 arine animals and the need to geographically scale up and prioritize conservation of high-value marin

35 Hence, they are bulky and hard to scale up and, more critically, typical carpet cloaks int

36 t presents a potential barrier to production scale-up and commercialization.

37 ose a new framework to accelerate viral load scale-up and ensure equitable access to this essential t

38 liance on GNA, which is unsuitable for large scale-up and global vaccine delivery.

39 e (HIVDR) as a consequence of aggressive ART scale-up and is actively promoting 3 key steps to mitiga

40 t the material is a viable candidate for the scale-up and removal of dye pollutants on a wider scale.

41 To demonstrate the ease of scale-up and synthetic potential of some organic solid s

42 he poorest countries, inhibiting progress in scaling up and also in achieving Roadmap goals.

43 ntally measured values, this method does not scale up, and is limited to small TMBs.

44 The reaction was amenable to scale up, and the enantioenriched quaternary alpha-nitro

45 , efficient linkage to care, rapid treatment scale-up, and adherence and retention interventions towa

46 HIV prevalence, sexual behaviours, treatment scale-up, and demographics.

47 emain including low power density, difficult scale-up, and durability of the cell components.

48 s in previously reported methods, is readily scaled up, and proceeds through stable intermediates sui

49 tial benefits of innovation are successfully scaled up, and that possible pitfalls are avoided.

50 ols used to isolate the EVs are difficult to scale up; and assays for efficacy are difficult to devel

51 elopment of this biofilter has the potential scaling-up application as gas-processing of industrial w

52 2D TMD layers, which remain impractical for scaled-up applications.

53 The capacity to prototype scaled up architectures of natural fabrics provides a ne

54 s suggest that future resource needs for ART scale-up are smaller than stated elsewhere but still sig

55 study provide a potential goal for surgical scale-up around the world.

56 Our findings support continued efforts to scale up ART coverage among HIV-positive PWUD.

57 acility-level financial resources needed for scaling up ART in these countries from 2015 to 2020 are

58 t is expected that the current WOP-EP can be scaled up as an efficient air-cleaning device to control

59 Greater political prioritisation is core to scale-up, as are policies that afford families time and

60 le structural barriers to implementation and scale-up at various levels.

61 Propagating to the proteome and scaling up at the metabolome, metabolic background depen

62 ) increase in odds of TDR since national ARV scale-up attributable to an increase in non-nucleoside r

63 the cost and complexity of VL is preventing scale-up beyond developed countries and there is a lack

64 ibility of maintaining high power density at scaled-up BMFCs was explored by arranging multiple anode

65 density and achieve high power output in the scaled-up BMFCs.

66 esearch is needed to test the feasibility of scaling up bubble CPAP in district hospitals and to impr

67 Effective scale-up can be achieved through health system and labor

68 The need to scale up cancer care in the low- and middle-income count

69 s, and new approaches to improve quality and scale up cancer surgical systems through education and t

70 apid solidification of chains and methods to scale up chain production.

71 n Pakistan and further emphasize the need to scale-up clinical and environmental surveillance as well

72 s wall material and a process feasible to be scaled-up: coacervation of soybean protein concentrate (

73 food (RUTF) is among the major obstacles to scaling up community-based management of acute malnutrit

74 These findings support substantial treatment scale-up, community-wide coverage, integrated treatment

75 For example, when scaling up control in the projected district from 10% to

76 dicting materials excited states properties, scaling up conventional GW calculations for large system

77 If scale-up costs are comparable, programs should add birth

78 major hurdles remain before optimization and scale-up could be achieved.

79 oves increasingly leverage carbon-finance to scale up dissemination of interventions.

80 respond to different environmental factors, scaling up diversity to the community level leads to an

81 (NTD), including lymphatic filariasis (LF), scaled up dramatically after the signing of the London D

82 Further investment in scaling up effective interventions in this area is urgen

83 adults had viral suppression, reflecting ART scale-up efforts to date.

84 adults had viral suppression, reflecting ART scale-up efforts to date.

85 N Initiative, in developing, validating, and scaling up emerging genomic and anatomical mapping techn

86 ines, as these can achieve a large effect if scaled up even if imperfectly efficacious.

87 the importance of implementation science in scaling up evidence-based interventions.

88 However, if impossible to scale up existing interventions to the extent assumed, e

89 onsultation with country stakeholders, which scaled up existing interventions to high but feasible co

90 Scaling up experiments in 12L barrels verified findings

91 h Africa, and analyzed scenarios of RPV PrEP scale-up for combination HIV prevention in comparison wi

92 cell densities developed towards the goal of scale-up for large animal pre-clinical studies.

93 rder of hundreds of nanoliters and cannot be scaled up for the preparative collection of charge varia

94 to result in ecological mismatches that can scale up from individual responses, to communities, to e

95 However, scaling-up from small, laboratory-sized experiments to h

96 ealth provides a critical starting point for scaling up, given its reach to pregnant women, families,

97 gs for children remains critical to ensuring scale-up globally.

98 Failure to scale up has severe personal and social consequences.

99 dom and model its trajectory with or without scaled-up HCV direct-acting antivirals (DAAs).

100 The epidemic was projected with current or scaled-up HCV treatment, with or without a 20% behaviora

101 trated by some of the successful examples of scale up identified in this paper.

102 1998 and 2009, which pre-dated the dramatic scale-up in ITN distribution and use.

103 can serve as development models for service scale-up in these regions, based on rigorous evaluation

104 human immunodeficiency virus (HIV) have been scaled up in many low- and middle-income countries.

105 mine the specific AMPAR subunit required for scaling up in CA1 hippocampal pyramidal neurons, and fou

106 re lengthy treatment programs that may limit scaling up in LMICs.

107 framework is an approach that is ripe to be scaled up, in particular through integration within nati

108 Scaling up interventions that are capable of increasing

109 We estimated the impact of scaling up interventions to reach the UNAIDS targets, as

110 .5% of the potential LBW births prevented by scaling up IPTp-SP would in fact have already have been

111 Furthermore, reaction scale up is often less problematic as this is addressed

112 innovative approaches are needed to address scale-up issues associated with the fabrication of the i

113 pact (PIA) and efficiency (NNT) at plausible scale-up levels.

114 however limited drug loading capacities and scale up limit their use.

115 Scaling up linear-optics quantum computing will require

116 f various 1,2,4-thiadiazole derivatives in a scaled-up manner with good to excellent yields using ine

117 The scaled-up manufacturing cost of Ni-MOF-74 synthesized vi

118 nse progress in antiretroviral therapy (ART) scale-up, many people still lack access to basic standar

119 les obsolescence method (SOM) and the survey scale-up method (SSUM), were used in order to compare th

120 The network scale-up method is a promising technique that uses sampl

121 searchers to continue to improve the network scale-up method.

122 Here, we scale up multiplexed smFISH to the transcriptome level a

123 cost-effectiveness studies of HIV treatment scale-up need to include health system constraints to be

124 crucial role in particle nucleation and the scale up of carbon capture and storage technology which

125 This work demonstrated the optimization and scale up of microwave-assisted extraction (MAE) and ultr

126 for future health programs with accelerated scale up of programs, to take a cautious approach on sup

127 force densities of 20 per 100 000 by 2030, a scale up of the surgical workforce is required.

128 IV infection declined significantly with the scale-up of a combination strategy for HIV prevention, w

129 tality rates since 2010, coincident with the scale-up of a community-wide "seek-and-treat" campaign.

130 For India, and particularly for China, full scale-up of all interventions in tuberculosis-programme

131 ciation between the incidence of HIV and the scale-up of antiretroviral therapy (ART) and medical mal

132 After the scale-up of antiretroviral therapy (ART) for human immun

133 for AIDS Relief (PEPFAR) supports aggressive scale-up of antiretroviral therapy (ART) in high-burden

134 2006 guidelines were developed prior to the scale-up of antiretroviral therapy (ART).

135 much of this decline is attributable to the scale-up of antiretroviral treatment (ART), as previous

136 Aggressive scale-up of any single intervention scenario could not a

137 ness of supply chains will likely impact the scale-up of both viral-load monitoring and HIVDR testing

138 n HCV transmission could be achieved through scale-up of DAAs and moderately effective behavioral int

139 V transmission may thus be expected from the scale-up of early ART, even in the context of behavioral

140 The scale-up of effective malaria control in the last decade

141 hemical and electrochemical instability, and scale-up of electrode films.

142 The scale-up of existing interventions (condom promotion, an

143 e of interventions, encompassing the further scale-up of existing interventions (promoting condom use

144 m effect on the epidemic is most affected by scale-up of existing interventions and the successful de

145 other approaches that can be used if further scale-up of existing interventions is limited.

146 Scale-up of existing interventions with increased invest

147 However, without scale-up of existing interventions, our model showed tha

148 tion impact would focus on strengthening the scale-up of existing interventions, while pursuing a wor

149 any of these gains could be achieved through scale-up of existing technologies and health services.

150 A large scale-up of eye care provision to cope with the increasi

151 highlight possibilities for the bioprinting scale-up of functional tissue and organ constructs for t

152 Further operational research to inform scale-up of hepatitis services is needed in low-income a

153 ystems and services would severely limit the scale-up of human immunodeficiency virus infection preve

154 st that this was achieved mainly through the scale-up of interventions that are effective against the

155 act of the UNAIDS targets will require rapid scale-up of interventions, particularly testing, ART ini

156 would place great emphasis on the following: scale-up of male circumcision and early ART initiation w

157 INTERPRETATION: Scale-up of male circumcision in sub-Saharan Africa has

158 the landmark WHA 54.19 resolution for global scale-up of mass administration of anthelmintic drugs fo

159 how emerging technologies might support the scale-up of mental health treatment and prevention effor

160 ffer a bright opportunity toward the use and scale-up of MES and AF for an economically viable acetic

161 found elsewhere, this would support further scale-up of MMC and ART for HIV prevention in sub-Sahara

162 h American cities and emphasize the need for scale-up of opioid agonist therapy and increased coverag

163 icted to be temporary, and in the absence of scale-up of other interventions, such as vector control,

164 QIseq has the potential to enable the scale-up of piggyBac-mediated genetics across multiple e

165 ntative expenditure over the 15 year period, scale-up of prevention along present funding channels co

166 A massive scale-up of rapid diagnosis and treatment is necessary t

167 Compared with no PrEP, prioritized scale-up of RPV PrEP in KwaZulu-Natal could be very cost

168 Compared with no PrEP, unprioritized scale-up of RVP PrEP covering 2.5%-15% of adults prevent

169 berculosis infection in at-risk populations, scale-up of short-course treatment regimens, engagement

170 We modelled the possible scale-up of surgical services in 88 low-income and middl

171 ance system or registry to monitor progress, scale-up of targeted testing for latent tuberculosis inf

172 Broad scale-up of TB control activities in Western Province wi

173 A scale-up of the ATH of 4-chromanone to the gram scale qu

174 In Ethiopia, extensive scale-up of the availability of health extension workers

175 Here, we report more than a 1,000-fold scale-up of the CMap as part of the NIH LINCS Consortium

176 to the period before 2006 (i.e., before the scale-up of the combination strategy for HIV prevention)

177 The scale-up of the present method was achieved at an isolat

178 Scale-up of the reaction and synthetic applications of t

179 The model did not involve the scale-up of the surgical workforce needed to address unm

180 mited data on the population-level effect of scale-up of these interventions in sub-Saharan Africa.

181 mise as novel separation platforms; however, scale-up of these membranes to large-areas remains an un

182 We compared scale-up of these regimens to a baseline reflective of c

183 titis C virus (HCV) therapies have spurred a scale-up of treatment to populations at greater risk of

184 Scale-up of vaccination coverage, innovations in scalabl

185 The plan included the introduction or scale-up of various new innovations and strategies, whic

186 Rwanda has achieved substantial progress in scaling up of antiretroviral therapy.

187 d forecasting of tOPV needs, bOPV licensing, scaling up of bOPV production and procurement, developin

188 The scaling up of breastfeeding to a near universal level co

189 Scaling up of effective interventions targeting the most

190 mate the impact of current interventions and scaling up of existing interventions for prevention of i

191 Scaling up of interventions for PWID remains a crucial p

192 Scaling up of opioid agonist therapies within prisons an

193 e little cross-talk, allowing for a dramatic scaling up of qubit number.

194 e do not show the characteristic homeostatic scaling up of the amplitude of miniature excitatory post

195 Scaling up of this system can be achieved by simply tuni

196 an papillomavirus (HPV) vaccine prices makes scaling up of vaccination programs attractive for countr

197 enable lattice design at the nanoscale; the scaling-up of nanolattice fabrication is currently the m

198 noscale CC-ZIFs are biocompatible and easily scaled-up offering excellent loading capacity and contro

199 ntiate (99m)Tc-CXCL8 SPECT as a biomarker to scale up or step down treatment with immune-modulating d

200 ted rewards followed the same function, just scaled up or down.

201 l-level health service coverage is gradually scaled up over time.

202 The costs of providing a significantly scaled up package of specified cost-effective interventi

203 evidence comes from small-scale studies, and scaling-up patterns of biodiversity-ecosystem functionin

204 orce the urgent need to overcome barriers to scaling up pediatric protease inhibitor-based regimens i

205 technology provides key benefits from safety/scale up perspectives.

206 Finally, the scale-up potential for continuous-flow reactors is descr

207 ardous oxidants, high interfacial areas, and scale-up potential.

208 broad spectrum of applications ranging from scaled-up power generation to medically related devices.

209 lementation of the CDC PrEP guidelines while scaling up PrEP coverage could result in a significant d

210 ed tropical diseases (NTDs), particularly to scale up preventive chemotherapy, surveillance, and elim

211 Scaled-up primary care integration of this intervention

212 Scaled-up production of these strains in benchtop biorea

213 Continued and enhanced efforts to scale up proven life-saving interventions are needed to

214 ostic tools and effective control options to scale up public health interventions and improve clinica

215 Emphasis is placed on scaled-up reactions and on purification procedures that

216 cedure for the preparation of NU-1000 can be scaled up reliably, and it is suitable for the productio

217 Although previous scale-up research has focused exclusively on networks of

218 , AED of 450J/mL are able to achieve similar scale up results.

219 cesses, and we present a one-step, multigram scale-up route for highly soluble 'scrambled' porous cag

220 Here, we present ideas for modernizing and scaling up snail control, including spatiotemporal targe

221 MSM in Bangkok, and the most cost-effective scale-up strategy.

222 ldhood development (Paper 1 of this Series), scaled up support for the youngest children is essential

223 ore analog syntheses as well as improved and scale-up syntheses.

224 s transformation is demonstrated through the scale-up synthesis.

225 this transformation is demonstrated through scaled-up synthesis.

226 Here, a novel approach is established to scale up the multidimensional fiber patterns of natural

227 They will play a vital role to scale up the number of users in quantum key distribution

228 emporal imaging (PARTI) system is devised to scale up the temporal recording length without sacrifici

229 The need to scale-up the primary prevention actions is urgent.

230 Scaling up the complexity and diversity of synthetic mol

231 reduction in mortality could be achieved by scaling up the coverage of infant vaccination (to 90% of

232 By scaling up the distribution of the predicted bodyweight

233 redict the behavior of multiple populations, scaling up the expectation and variance of the dynamics

234 and manipulation can be achieved by linearly scaling up the number of phototransistors and device are

235 With no fundamental obstacles for scaling up, the technology's simplicity, efficiency and

236 are already doing in vivo patch clamping to scale up their efforts by reducing training time for new

237 However, it remains challenging to scale up these circuits owing to the limited number of d

238 The annual incremental cost of immediately scaling up these essential interventions would be US$6.2

239 hen, using engineering rendering software to scale up this natural tissue fabric, as well as multidim

240 humanitarian contexts and supports calls to scale up this research.

241 stigate the population-level implications of scaling up this new regimen.

242 1) ensuring adequate financial investment in scaling up this test; (2) achieving pricing agreements a

243 e this knowledge into real-world practice by scaling-up this programme through the National Mental He

244 neficial and unsuitable for industrial grade scale-up, this study accomplished the task of optimizing

245 Despite several attempts, bioprinting of scale-up tissues at clinically-relevant dimensions with

246 delivery medium, and facilitated native-like scale-up tissues.

247 ith 1 mum channel reaches 33 GHz/17 GHz, and scale up to 350 GHz/53 GHz for 100 nm channel (assuming

248 . growth, survival and dispersal), which can scale up to affect population rates of growth and spread

249 t sub-lethal effects of neonicotinoids could scale up to cause losses of bee biodiversity.

250 ivers of population dynamics that ultimately scale up to determine community structure.

251 on of multi-scale microstructures, and their scale up to industrial-size manufacturing is emphasized

252 ysiological functions, but how these effects scale up to influence competition, a key driver of commu

253 ic variant calling strategies either fail to scale up to large datasets or abandon joint calling stra

254 ucture were manufactured, with potential for scale up to much larger gel dimensions.

255 int variant calling and imputation which can scale up to over 10,000 samples while producing SNV call

256 iations, but how microevolutionary processes scale up to shape the expansion of phenotypic diversity

257 With potential for simple scale up to volume manufacturing though standard semicon

258 .2g/L were produced in W and WH in a further scale-up to 5L bioreactors, confirming the suitability o

259 With DAA scale-up to 80% within 1 year of diagnosis (regardless o

260 To examine a realistic scale-up to larger models or potentially patients for su

261 buted computing framework, which allows easy scale-up to manage the large amounts of data expected to

262 a metal-free one-pot synthesis, and ease of scale-up to multigram quantities.

263 oduction of a 50%-efficacy vaccine gradually scaled up to 70% coverage.

264 al groups on the starting alkynes and can be scaled up to a gram scale.

265 The protocol was successfully scaled up to a multigram scale and the catalyst was succ

266 esponded to conventional therapy is commonly scaled up to biological agents, but surgery can also off

267 Cardiopatches can be scaled up to clinically relevant dimensions, while prese

268 ith different functional groups and has been scaled up to gram level.

269 The reaction was scaled up to gram quantities by using a flow-chemistry p

270 The CTFs synthesized were also readily scaled up to gram quantities.

271 the use of single substrates, and a reaction scaled up to grams make this strategy very attractive an

272 Comparative phylogeographic analyses scaled up to large geographic regions and hundreds of sp

273 ws for existing algorithms to be efficiently scaled up to operate on large sets of alignments.

274 t-effective health interventions that can be scaled up to reduce maternal, newborn, and child deaths,

275 However, when scaled up to the entire 1 km restoration reach with a si

276 mmercial nanotechnology, as it can be easily scaled up to the fabrication of staple nanofibers at rat

277 ogies can enable metabolic engineering to be scaled up to the industrial level, either by cutting off

278 When scaled up to the population level, long-term exposure to

279 duals initiate ART could be substantial when scaled up to the population level.

280 served patterns, especially at small spatial scales (up to [Formula: see text]4,000 km).

281 effect of temperature on metabolic processes scales up to animal movement and beyond.

282 simulator (ARGON) for the DTWF process that scales up to hundreds of thousands of samples and whole-

283 Furthermore, cellular succulence scales up to morphological succulence according to vario

284 nsight into how the behavior of single cells scales up to processes at the population level provides

285 longitudinal stress propagation over length scales up to several tens of nanometers before damping.

286 Scaling-up to the country level, paramo peatlands likely

287 not require an external oxidant, is readily scaled up (up to 98 mmol), and the structurally diverse

288 Future studies should address how to scale up use of the resources, long-term effects, includ

289 (up to 96% ee), and is amenable to decagram scale-up using catalyst loadings as low as 0.05 mol %.

290 However, due to technical issues scaling up vaccine production and an unforecasted demand

291 There is therefore an urgent need to scale up vector control and access to health care for ru

292 This study provides additional rationale for scaling up violence prevention interventions that combin

293 ies implement the 2015 WHO recommendation to scale up viral load monitoring.

294 For countries that have just started to scale up viral load testing, lessons can be learnt from

295 ncorrected presbyopia, highlight the need to scale up vision impairment alleviation efforts at all le

296 uld be a financially sustainable approach to scale up water treatment and improve health in low-incom

297 bserved that the process is not sensitive to scale-up, which is essential for its future translation

298 f pulmonary tuberculosis in children and its scale-up will improve access to tuberculosis diagnostics

299 rameters are higher at the island center and scale up with island size, which we confirmed experiment

300 on proceeds under mild conditions and can be scaled up without compromising the asymmetric induction.