ライフサイエンスコーパス: scallop

1 ent subcommissures between posterior leaflet scallops.

2 Here we investigate the complex eye of scallops.

3 nsitive to the precise temporal structure of scallops.

4 , we conclude that seismic exposure can harm scallops.

5 nsitive to the precise temporal structure of scallops.

6 oped switches the DNA-binding selectivity of Scalloped.

7 ories: thin-scalloped, thick-flat, and thick-scalloped.

8 Scallop achieves higher sensitivity and precision than p

9 izzard regulatory light chain (RLC) bound to scallop adductor muscle myofibrils in key physiological

10 two alpha-helical strands of a model of the scallop alpha-helical coiled coil.

11 We introduce Scallop, an accurate reference-based transcript assemble

12 he motor and the lever is similar in rabbit, scallop and chicken S1.

13 ependent on (a) conjunctive presentations of scallop and light, (b) number of conditioning trials, an

14 ombined action of the general wing activator Scalloped and a putative locally provided factor, the ac

15 hereas 30 (31.3%) and four (8.2%) with thick-scalloped and thin-scalloped biotypes, respectively, had

16 rthermore, combinations of binding sites for SCALLOPED and transcriptional effectors of signaling pat

17 The proteins Scalloped and Vestigial are known from genetic studies t

18 studies highlight the importance of correct scalloped and vestigial expression levels to normal wing

19 The scalloped and vestigial genes are both required for the

20 xity and, consistent with this, we show that Scalloped and Vestigial suppress terminal dendritic bran

21 t sensory neurons by selective expression of Scalloped and Vestigial.

22 ctor Cut, and the transcriptional regulators Scalloped and Vestigial.

23 Scalloped and Yorkie, transcriptional effectors of the H

24 patterns, including nodulation, banding and scallops and fingers.

25 Applied to scallops and related clades, we find that accumulating k

26 with partial detection in molluscs: mussels, scallops and snails but none in oyster, octopus and squi

27 d pre-stroke conformations of Dictyostelium, scallop, and chicken myosin II as well as Dictyostelium

28 of scalloped function, ectopic expression of scalloped, and ectopic expression of vestigial on the de

29 e nAChR/microsphere-based assay for mussels, scallops, and clams.

30 ies of scalloped mutant clones, implies that scalloped- and vestigial-dependent cell adhesion contrib

31 leaflet coaptation by drawing the individual scallops apart.

32 Endoscopic findings included scalloping appearance, mucosal cracking, and redness of

33 Our results suggest that clams and scallops are unlikely to acclimate to ocean acidificatio

34 ations that cause loss of wing tissue (e.g., scalloped, Beadex, cut, and apterous-Xasta), Lyra wing d

35 had mitral valve repair involving >1 leaflet scallop between October 2001 and July 2010.

36 These findings expand the roles for Yorkie/Scalloped beyond growth to encompass specific cell-fate

37 Vestigial protein that are not required for Scalloped binding in solution are required for the forma

38 nd four (8.2%) with thick-scalloped and thin-scalloped biotypes, respectively, had APE.

39 The effect of Pi on the E2 form of the scallop Ca-ATPase was also investigated, when it was fou

40 binding site for substrate on the E1 form of scallop Ca-ATPase was occupied by Pi, AMP-PNP, AMP-PCP,

41 mentation patterns of the E1 and E2 forms of scallop Ca-ATPase were examined.

42 In cells, Nwk-induced scallops can be extended by cytoskeletal forces to produ

43 main, corresponding to one type found in sea scallop catch ("smooth") muscle.

44 This reconstituted LCD is of a sea scallop catch muscle myosin with its phosphorylatable re

45 kely to act as an on-switch in regulation of scallop catch muscle myosin.

46 various transcriptomes, and proteomes of the scallop Chlamys farreri, a semi-sessile bivalve with wel

47 The hyperpolarizing receptor potential of scallop ciliary photoreceptors is attributable to light-

48 formation of the heterotetrameric Vestigial-Scalloped complex on DNA.

49 0.6 mm laterally away from the posteromedial scallop, corresponding to anterior displacement of the m

50 ired with durable results when simple single-scallop disease is addressed.

51 perpolarizing, ciliary photoreceptors of the scallop does not use IP3-mediated Ca release, and the li

52 anipulated the temporal structure of natural scallops during behavioral playback and in vivo electrop

53 yses of the marine bivalve clade Pectinidae (scallops) during a major Plio-Pleistocene extinction in

54 onstrate that phenotypic expressivity of the scalloped(E3) (sd(E3)) mutation of Drosophila melanogast

55 Coins with scalloped edges or holes should be endoscopically remove

56 gy due to Gaussian curvature associated with scalloped edges, demonstrating that colloidal membranes

57 me unstable, instead forming structures with scalloped edges, where two adjacent lobes with opposite

58 riments to probe the temporal sensitivity of scallop encoding and recognition.

59 cortical thickening (33 patients), cortical scalloping/erosion (37 patients), and/or perpendicular p

60 , (b) number of conditioning trials, and (c) scallop extract concentration.

61 In general, the scallop extract potentiated phototactic suppression.

62 ctic behavior by compound pairings of light, scallop extract, and rotation were assessed.

63 The sole crystallin of the scallop eye lens was found to be homologous to Omega-cry

64 Within the scallop eye, immunofluorescence tests indicated that Ome

65 Cells overexpressing scalloped fail to proliferate in both notal and wing-bla

66 lones of cells mutant for a strong allele of scalloped fail to proliferate within the wing pouch, but

67 le image reconstruction of Ca(2+)-regulated (scallop) filaments reveals a helical array of myosin hea

68 ed from single neurons discriminated natural scallops from time-reversed, randomized, and jittered se

69 nalyzed the consequences of complete loss of scalloped function, ectopic expression of scalloped, and

70 Scallop heavy meromyosin (HMM) preparation obtained by a

71 Further, Yorkie or Scalloped hyperactivation induced ectopic crystal cells

72 Genetic manipulation of yorkie and scalloped in the lymph gland specifically alters Serrate

73 nting time-reversed, randomized, or jittered scallops increased behavioral response thresholds, demon

74 In Drosophila, the TEF-1 homolog Scalloped interacts with the cofactor Vestigial to drive

75 usly, but at temperatures near 0 degrees C a scalloped interface morphology appeared with convex and

76 The Drosophila TEAD ortholog Scalloped is required for Yki-mediated overgrowth but is

77 Scallop larvae exposed to playbacks of seismic pulses sh

78 noise sources to affect recruitment of wild scallop larvae in natural stocks.

79 evation (44%), hyporeflective vessels (40%), scalloped layers (22%), and retinal spaces (11%).

80 Omega-crystallin of the scallop lens is an inactive aldehyde dehydrogenase (1A9)

81 The primary geometric mechanism underlying scallop malcoaptation in acute ischemic mitral regurgita

82 Interactions between scalloped, mastermind and Chip mutations indicate that m

83 Mutations in scalloped, mastermind, and a previously unknown gene, Ch

84 immunoassays performed well with mussel and scallop matrixes displaying adequate dynamic ranges and

85 hows that the increase in the edge energy of scalloped membranes is compensated by concomitant decrea

86 embranes attached to chromatin with a unique scalloped morphology, but these nuclei neither accumulat

87 In all patients, mucosal changes of scalloping, mucosal mosaicism and reduced folds were see

88 Fully functional scallop muscle fibers were prepared such that each myosi

89 abeled regulatory light chains in functional scallop muscle fibers.

90 y of spin-labeled regulatory light chains in scallop muscle fibers.

91 the light chain domain of myosin in relaxed scallop muscle fibers.

92 Digestion of scallop muscle membrane fractions with trypsin led to re

93 ist within the Ca(2+) regulatory domain of a scallop muscle Na(+)-Ca(2+) exchanger that mediates dire

94 paramagnetic resonance (EPR) of spin-labeled scallop muscle, in conjunction with laser flash photolys

95 is of these clones, together with studies of scalloped mutant clones, implies that scalloped- and ves

96 sory organ development and can rescue a wing scalloping mutant phenotype associated with loss of cut

97 Native RLC from scallop myofibrils was extracted and replaced completely

98 Single-headed scallop myosin (shM) was prepared by papain digestion of

99 prepared by papain digestion of filamentous scallop myosin and purified by hydrophobic interaction c

100 tion of the ATPase activity of single-headed scallop myosin by Ca2+ paralleled closely the Ca2+ bindi

101 ed coil rod, contribute to the regulation of scallop myosin by Ca2+.

102 disrupt their predicted interactions (using scallop myosin coordinates), we measured basal ATPase, V

103 The 3.1-A x-ray structure of the scallop myosin head domain (subfragment 1) in the ADP-bo

104 Docking of atomic models of scallop myosin head domains into the motifs reveals that

105 have determined the structure of the intact scallop myosin head, containing both the motor domain an

106 We conclude that in the "off" state, scallop myosin heads interact with each other, forming a

107 e entire coiled-coil, a study is made of the scallop myosin II S2 subdomain for which an x-ray struct

108 The mechanism of calcium regulation of scallop myosin is not understood, although it is known t

109 Here we report a 2.3-A crystal structure of scallop myosin S1 complexed with ADP.BeF(x), as well as

110 ermined a 3.2-A nucleotide-free structure of scallop myosin S1, which suggests that in the near-rigor

111 Atomic structures of scallop myosin subfragment 1(S1) with the bound MgADP, M

112 In scallop myosin, the region corresponding to Glu124-Arg14

113 und SH1 helix first seen in an unusual 2.5-A scallop myosin-MgADP structure and described as correspo

114 pin labels bound to the regulatory domain of scallop myosin.

115 Previous studies in vertebrate and scallop myosins have shown a correlation between actin f

116 8-mm diameter hole was punched in the middle scallop of the posterior mitral leaflet to create "pure"

117 overexpression in the chick limb results in scalloping of the AER and limb truncations, suggesting t

118 nts, fusion of the cerebral hemispheres, and scalloping of the dentate gyrus.

119 visualization of the MV (85% to 91% for all scallops of both MV leaflets), interatrial septum (84%),

120 he clip successfully approximated the middle scallops of the anterior and posterior leaflets in all 1

121 designed to grasp and approximate the middle scallops of the anterior and posterior mitral leaflets w

122 surgical technique approximating the middle scallops of the mitral leaflets to create a double orifi

123 Scallop Omega-crystallin (officially designated ALDH1A9)

124 Like other enzyme-crystallins, scallop Omega-crystallin appears to be present in low am

125 Here we have cloned the scallop Omega-crystallin gene.

126 -crystallins, which are tetrameric proteins, scallop Omega-crystallin is a dimeric protein.

127 ave a structure very similar to human ALDH2, scallop Omega-crystallin was enzymatically inactive with

128 s into zigzags, creating ridges and periodic scallops on membranes in vitro.

129 During "scallops", only DP-PCN neurons with high baseline firing

130 hologically, having a cylindrical shape with scalloped or "nibbled" edges.

131 Relative to mutations in scalloped or mastermind, a Chip mutation hypersensitizes

132 The CT scan showed scalloping over the right supra-orbital ridge with an in

133 om the different samples evaluated (mussels, scallops, oysters, clams, cockles) nor interference from

134 the cloning and sequencing of mtDNA from the scallop Pecten maximus, and were used to study genetic d

135 ave now determined the structure of the same scallop peptide in three additional crystal environments

136 two classes of visual cells, we examined in scallop photoreceptors the effects of several antagonist

137 Hyperpolarizing scallop photoreceptors, like vertebrate rods, use cGMP a

138 spin-labeled regulatory light chain (RLC) in scallop (Placopecten magellanicus) muscle fibers.

139 Scallop preserves long-range phasing paths extracted fro

140 On 10 human RNA-seq samples, Scallop produces 34.5% and 36.3% more correct multi-exon

141 A TEA DNA-binding domain in the Scalloped protein binds the wing margin enhancer.

142 wing identity by forming a complex with the Scalloped protein that binds sequence specifically to es

143 that Vestigial requires the function of the Scalloped protein, a member of the TEA family of transcr

144 Many other organisms, such as scallops, rarely swim at Re less than 100.

145 rmined the crystal structure of a molluscan (scallop) RD in the absence of Ca(2+).

146 real bevacizumab results in a characteristic scalloped regression pattern that is highly associated w

147 edge in a stereotyped pattern, suggestive of scalloped regression.

148 sin molecule has been created by attaching a scallop regulatory domain to the end of each of the two

149 .01), hyporeflective vessels (P = 0.04), and scalloped retinal layers (P = 0.006).

150 scans for (1) retinal vessel elevation, (2) scalloped retinal layers, (3) hyporeflective vessels, an

151 The scallop's large striated muscle is energy-dynamic but no

152 of those genes may have profound effects on scallop's phenotype and adaptation.

153 on for destabilization of this helix in some scallop S1 but not in other S1 isoform structures.

154 with the previously determined structure of scallop S1 complexed with MgADP (which we interpret as a

155 ule at this resolution: it too resembles the scallop S1 crystal structure.

156 monly closely resemble the appearance of the scallop S1 structure rather than the methylated chicken

157 The rate of monofunctional labeling of scallop S1 was increased in the presence of MgADP and Mg

158 factors that influence the SH1-SH2 helix in scallop S1 were examined using monofunctional and bifunc

159 by the initial attachment of the reagent to scallop S1.

160 ond between SH1 and SH2, were much faster in scallop S1.ADP than in rabbit skeletal S1.ADP and were r

161 so compared the melting temperatures of this scallop S2 peptide with those of analogous peptides from

162 imulations on an existing x-ray structure of scallop S2 yielded force spectra with either two or thre

163 hat the TEAD/TEF family transcription factor Scalloped (Sd) acts together with the coactivator Yorkie

164 Here we identify the TEAD/TEF family protein Scalloped (Sd) as a DNA-binding transcription factor tha

165 The TEAD/TEF factor Scalloped (Sd) has been identified as the first known tr

166 Surprisingly, expression of Yorkie (Yki) and Scalloped (Sd) in salivary glands fails to phenocopy wts

167 ulates downstream target genes together with Scalloped (Sd), a DNA-binding protein.

168 or Yorkie (Yki) and the transcription factor Scalloped (Sd), leading to activation of Yki target gene

169 a complex with Yki and its binding partner, Scalloped (Sd), on target-gene promoters and is essentia

170 a complex with DNA-binding proteins such as Scalloped (Sd).

171 the TEAD/TEF family of transcription factor Scalloped (Sd).

172 A characteristic scalloping seen on imaging (depression in the outer or i

173 The Scalloped selector protein controls wing development in

174 d by Drosophila TCF (dTCF) and the Vestigial/Scalloped selector system and that temporal control is p

175 re sensitive to interindividual variation in scallop sequences, raising the question of whether fish

176 uorescence, it localized in densely staining scalloped-shaped distortions of the nuclear membrane in

177 Furthermore, scallops showed persistent alterations in recessing refl

178 licit energetically expensive behaviors, but scallops showed significant changes in behavioral patter

179 le frequencies in Aequipecten opercularis, a scallop species with a similar distribution and life his

180 the alphaTN4-1, L929, and Cos7 cells and the scallop stomach and oligonucleotides derived from the pu

181 In scallop striated adductor muscle, the disordering that t

182 position of Tm in native thin filaments from scallop striated adductor muscle.

183 s completely and specifically extracted from scallop striated muscle fibers, eliminating the Ca sensi

184 t (51 residues plus a leucine zipper) of the scallop striated muscle myosin isoform.

185 structure of a proteolytic subfragment from scallop striated muscle myosin, complexed with MgADP, ha

186 a leucine-zipper-stabilized fragment of the scallop striated-muscle myosin rod adjacent to the head-

187 the motifs are similar in both systems, the scallop structure is more tilted and higher above the fi

188 ing the question of whether fish may analyze scallop structure to gain information about the sender.

189 front door." In addition, using a variety of scallop structures, including a relatively high-resoluti

190 -0.6 mm apically away from the anterolateral scallop; such displacement correlated with lateral displ

191 We show that binding of Vestigial to Scalloped switches the DNA-binding selectivity of Scallo

192 cofactors that interact with members of the Scalloped/TEAD family of transcription factors and modul

193 a member of the ATTS/TEA (AbaA, TEF-1, TEC1, Scalloped/TEF-1, TEC1, AbaA) class of transcription fact

194 rved in Drosophila Yki (the YAP homolog) and Scalloped (the TEAD homolog).

195 It is shown that SCALLOPED, the DNA binding component of the selector pro

196 We provide evidence that Yorkie and Scalloped, the Drosophila homologs of YAP and TEAD, are

197 We show that the constraints of the scallop theorem can be escaped in frictional media if tw

198 The Scallop theorem states that reciprocal methods of locomo

199 number is subject to the constraints of the scallop theorem, which dictate that body kinematics iden

200 hich was divided into three categories: thin-scalloped, thick-flat, and thick-scalloped.

201 of Tm is consistent with the hypothesis that scallop thin filaments are Ca(2+) regulated.

202 on vehicles of transmission were undercooked scallops (three outbreaks caused by enterotoxigenic Esch

203 t that Vestigial affects the conformation of Scalloped to create a wing cell-specific DNA-binding sel

204 mastermind and Chip act synergistically with scalloped to regulate the wing margin enhancer.

205 The scallop uses hepatopancreas to accumulate neurotoxins an

206 the impact of exposure to seismic surveys on scallops, using measurements of physiological and behavi

207 ceptor pathway in the wing margin, including scalloped, vestigial, mastermind, Chip, and the Nipped l

208 ent of the posteromedial edge of the central scallop was 1.4+/-0.9 mm anteriorly and 0.9+/-0.6 mm lat

209 stole, the anterolateral edge of the central scallop was displaced 0.8+/-0.9 mm laterally and 0.9+/-0

210 ich interact with the ELC (Ca(2+) binding in scallop), was sufficient to abolish motility and diminis

211 Yorkie and its partner transcription factor Scalloped were found to regulate transcription of the Ru

212 an individually stereotyped signal called a scallop, which consists of a distinctive temporal patter

213 Malcoaptation of the scallops within the posterior leaflet during acute left

214 ree-dimensional dynamics of the 3 individual scallops within the posterior mitral leaflet during acut