ライフサイエンスコーパス: scam

1 e substituted cysteine accessibility method (SCAM).

2 e substituted cysteine accessibility method (SCAM).

3 e substituted cysteine accessibility method (SCAM).

4 e substituted cysteine accessibility method (SCAM).

5 ow been analyzed by scanning mutagenesis and SCAM.

6 ved in spine/synapse maturation, Shank and S-SCAM.

7 y other GPCR in which TM6 has been mapped by SCAM.

8 nts of decision making and susceptibility to scams.

9 decisions and are selectively vulnerable to scams.

10 herapy resulted in a significant decrease in sCAMs.

11 d a self-report measure of susceptibility to scams.

12 SCaM-1 and M144V produced greater inhibition of NOS's ox

13 r the protein phosphatase calcineurin (CaN); SCaM-1 half-maximally activated mammalian CaN at approxi

14 SCaM-1 is a plant calmodulin (CaM) isoform that is 91% i

15 A V144M back mutation in SCaM-1 significantly restored its ability to activate NO

16 thionine at position 144, is responsible for SCaM-1's inhibition of mammalian NOS.

17 xide synthase (NOS) at 180 nM while another (SCaM-1) served as a competitive antagonist (Ki approxima

18 r competitive antagonism of NOS, M144V, like SCaM-1, exhibited a similar dose-dependent activation of

19 with a similar K(i) (approximately 15 nM) as SCaM-1.

20 ed mammalian CaN at approximately 12 nM, and SCaM-4 competitively antagonized (Ki approximately 70 nM

21 One cloned soybean CaM isoform (SCaM-4) half-maximally activated mammalian nitric oxide

22 lication of Synaptic Scaffolding Molecule (S-SCAM, also called MAGI-2), which encodes a postsynaptic

23 rt that the synaptic scaffolding molecule (S-SCAM; also called membrane-associated guanylate kinase i

24 vel of decision making and susceptibility to scams; analyses controlled for age, sex, education, and

25 l substituted cysteine accessibility method (SCAM) and a new fluorescence binding assay.

26 The SCAM approach involved a systematic probe of receptor st

27 g levels of soluble cell adhesion molecules (sCAMs) are more pronounced in DM2-MV than in DM2 and con

28 We identify S-SCAM as a novel component of neuronal nicotinic synapses

29 PSD-93 and S-SCAM bind to APC and its binding partner beta-catenin, r

30 to decreased postsynaptic accumulation of S-SCAM, but not PSD-93.

31 validate a causal relationship of the rare S-SCAM CNV and provide supporting evidence for the rare CN

32 The SCAM data were consistent with a C-terminus at 4.58, but

33 Combining the SCAM data with rhodopsin-based molecular models of the r

34 in vivo functional characterization, in vivo SCAM, electrophysiological studies, and disulfide-trappi

35 study, using a method coined as the "in vivo SCAM", identified several residues in the channel pore t

36 The levels of sCAMs in malaria are thus not an accurate reflection of

37 e substituted cysteine accessibility method (SCAM) in transmembrane domains 6 (TM6) and 7 (TM7) and e

38 Further, S-SCAM increased surface AMPAR levels in the absence of PS

39 Together, these results suggest that S-SCAM is an essential AMPAR scaffolding molecule for the

40 he earliest identifiable podocytes, MAGI-2/S-SCAM is first detected in junctional complexes in podocy

41 e induction of long term-depression, while S-SCAM knockdown did not.

42 Conversely, decreasing S-SCAM levels by RNA interference-mediated knockdown cause

43 g the duplication conditions, elevation of S-SCAM levels in excitatory neurons of the forebrain was s

44 Increasing S-SCAM levels in rat hippocampal neurons led to specific i

45 tion in skin biopsies did not correlate with sCAM levels or disease severity.

46 x proteins from glomerular lysates, MAGI-2/S-SCAM (membrane-associated guanylate kinase inverted 2/sy

47 Finally, S-SCAM overexpression hampered NMDA-induced internalizatio

48 ision making and increased susceptibility to scams (p's<0.001).

49 tween cognitive decline, decision making and scams persisted in analyses restricted to persons withou

50 We show that S-SCAM, PSD-93, neuroligin and neurexin are enriched at al

51 Importantly, S-SCAM regulated synaptic AMPAR levels in a manner, depend

52 e CB2 binding pocket, further confirming our SCAM results.

53 Seven SCAM-sensitive residues (S3107.33, F3147.37, and I3167.3

54 shoplifting were making money illegally and scamming someone for money.

55 to the accessibility patterns determined by SCAM studies of TMH6 in the opioid and dopamine D2 recep

56 the Xenopus oocyte expression system and the SCAM (substituted cysteine accessibility method), we fou

57 S-SCAM (synaptic cell adhesion molecule) and PSD-93 (posts

58 inase inverted-2), a protein also known as S-SCAM (synaptic scaffolding molecule).

59 MAGI-2 [also known as S-SCAM (synaptic scaffolding molecule)] is a multi-PDZ dom

60 e of PSD-95, while PSD-95 was dependent on S-SCAM to increase surface AMPAR levels.

61 e substituted-cysteine accessibility method (SCAM) to map the residues in the sixth membrane-spanning

62 e substituted cysteine accessibility method (SCAM) to map the residues of the transmembrane helices (

63 d substituted cysteine accessibility method (SCAM) to provide new evidence for a centrally located ga

64 e substituted-cysteine-accessibility method (SCAM) to the M2 segment and the M1-M2 loop of the acetyl

65 Furthermore, the S-SCAM transgenic mice provide a valuable new animal model

66 Notably, the S-SCAM transgenic mice showed a unique sex difference in s

67 S-SCAM transgenic mice showed an increased number of later

68 e substituted cysteine accessibility method (SCAM) was applied to the first membrane-spanning segment

69 e substituted-cysteine accessibility method (SCAM) was applied to transmembrane span seven of the hum

70 e substituted-cysteine-accessibility method (SCAM), we are mapping the residues that contribute to th

71 e substituted-cysteine-accessibility method (SCAM), we are mapping the residues that contribute to th

72 e substituted cysteine accessibility method (SCAM), we defined the VirB2 IM topology and then identif

73 e substituted cysteine accessibility method (SCAM), we evaluated the role of possible pore-lining res

74 sidues to thiol blockers (a technique called SCAM), we have identified the pore-lining residues of a

75 e substituted cysteine accessibility method (SCAM), we previously mapped the residues in the third, f

76 helium and increased levels of soluble CAMs (sCAMs), were seen in both severe and uncomplicated malar

77 jects and of decreased monocyte activity and sCAMs with AT therapy in diabetic subjects with and with

78 ituted cysteine (Cys) accessibility methods (SCAM) with sodium (2-sulfonatoethyl)methanethiosulfonate