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1 is function on ANO1, which normally does not scramble.
2 d treated with miR-24 inhibitor or inhibitor scramble.
3 ent noise modulation segments was temporally scrambled.
4 cyclic products are directionally uniform or scrambled.
5 mutant mice, in which neural positioning is scrambled.
6 impaired Ca(2+)-triggered phosphatidylserine scrambling.
7 insertion of loxPsym sites to enable genome scrambling.
8 een shown to be involved in Ca(2+)-dependent scrambling.
9 they are scramblases or channels regulating scrambling.
10 cyclophilin D/TMEM16F-dependent phospholipid scrambling.
11 , including Bronsted acid-catalyzed C-F/Co-C scrambling.
12 ndrome with deficient Ca(2+)-dependent lipid scrambling.
13 usly involves both Ni-H moieties without H/D scrambling.
14 nels and regulators of membrane phospholipid scrambling.
15 brane-protein interactions involved in lipid scrambling.
16 ff' = 0 [0 to 25]%, 'On' = 69 [53 to 100]%, 'Scrambled' = 28 [13 to 63]%; Friedman Chi-squared test s
17 Off' = 0 [0 to 50]%, 'On' = 69 [67 to 95]%, 'Scrambled' = 59 [42 to 95]%; Friedman Chi-squared test s
18 c with 1 except that the targeting region is scrambled (a YI-YI motif, see text), showed that 1 is co
25 that the addition of PRD to hPLSCR2 restored scrambling activity, and deletion of PRD in hPLSCR1 (Del
26 SCR2 showed Ca(2+)-dependent aggregation and scrambling activity, whereas hPLSCR2 and DeltaPRD-hPLSCR
27 ghput gene synthesis, here we report a codon-scrambling algorithm that enables the PCR-based gene syn
30 and the rate of endocytosis observed in both scrambled and ClC-5 knockdown cells were not significant
31 ectivities is a necessity to avoid disulfide scrambled and incorrectly folded forms in the final prod
32 served regions of its primary structure were scrambled and the mutations were tested for the RD3 abil
36 ), provides steric protection against ligand scrambling and metal complex oligomerization and electro
38 n inverse kinetic isotope effect, fast H2/D2 scrambling and slow alkene isomerizations pointing to an
39 ase fragment ion isomers related to sequence scrambling and the underlying fragmentation mechanism, w
41 d key amino acids necessary for phospholipid scrambling and validated the idea that ions permeate TME
42 membrane induced by oxidative stress, lipid scrambling, and artificial cell aging modulate the cell
43 sin to metarhodopsin II are not required for scrambling, and that the lipid translocation pathway eit
44 d, to determine the extent of disulfide bond scrambling, and to understand why scrambling occurs, we
45 randomizing effects from vibrational energy scrambling are avoided, and excitation-energy specific r
47 eptide, we show that UVPD occurs without H/D scrambling as the peptide probe accurately retains its s
48 lisinopril (100 mg/kg/d), PBS (control), or scrambled ASO (66 mg/kg/wk) for 10 wk, followed by tissu
49 onucleotides (ASOs) to knockdown Mogat1 or a scrambled ASO control for 12 weeks while remaining on di
51 zing a (2)H-labeled silolane probe; complete scrambling at the silicon center was observed, consisten
52 ed Cu(I)Cu(II) pair; the Cu(II), however, is scrambled between the two locations within the dicopper
53 observed both while viewing coherent versus scrambled biological motion, and while listening to happ
54 Synteny analysis uncovered localized but scrambled blocks of genes in putative orthologous relati
58 developed elaborate eccentricities, such as scrambled coding regions, nonstandard genetic codes, and
59 rization-sensitive OCT imaging, polarization-scrambling columns were found at the level of the RPE.
60 aluated in cells transfected with miR-29b or scramble control and treated with TGFbeta2, and the expr
62 se oligodeoxynucleotides targeting Notch3 or scramble control oligodeoxynucleotides in wild-type mice
63 obscurin short hairpin RNA (shRNA), but not scramble control shRNA, exhibit increased primary tumor
65 and 61% (all p<0.001), respectively, versus scrambled control and decreased COL1A1 protein by 60% (p
66 o be in the Cdc42/ciliogenesis pathway and a scrambled control morpholino showed no phenotypic effect
68 randomized to receive anti-miR-21 (KD21) or scrambled control sequence (Scr21) injections into the l
69 mals received a comparable vector encoding a scrambled control short hairpin RNA (control vector).
70 tide depletion in adult rats, CART shRNAs or scrambled control shRNAs were administered bilaterally i
74 CI, 0.30-0.36]; P = .02; mean for miR-34b vs scrambled control, 0.31 RLU [95% CI, 0.30-0.32]; P = .01
75 ase (mean luciferase activity for miR-34a vs scrambled control, 0.33 RLU [95% CI, 0.30-0.36]; P = .02
76 0.30-0.32]; P = .01; and mean for miR-34c vs scrambled control, 0.35 RLU [95% CI, 0.33-0.37]; P = .02
78 ased baseline Tshb mRNA levels compared with scrambled control, but surprisingly had no affect on the
79 rostate cancer cell xenografts compared with scrambled controls, suggesting HIP1R is a key functional
81 oron-dipyrromethene (IYIY-I2-BODIPY) and its scrambled counterpart YIYI-I2-BODIPY have been prepared.
82 unmodified or lesion-containing CRE, but not scrambled CRE or scrambled CRE with a G/U mispair, resul
83 ion-containing CRE, but not scrambled CRE or scrambled CRE with a G/U mispair, resulted in increased
84 Gly(6)-Gln(7) residues or by random sequence scrambling demonstrated a crucial role for this structur
86 ration of the lack of a significant level of scrambled disulfide bonds are critical to ensure the app
87 disulfide linkage and the ability to detect scrambled disulfide bonds from a single experiment with
93 ium-labeling studies indicate that deuterium scrambling does not take place in this sp(2) -sp(3) cros
95 r use in RT-PCR diagnostics: we encapsulated scrambled Ebola RNA sequences inside of tobacco mosaic v
96 owder reached 1g, it was replaced with 8g of scrambled egg, after then subsequent doses were increase
97 e top-down routine does not trigger hydrogen scrambling either during the electrospray ionization pro
99 urements appear to be unaffected by hydrogen scrambling, even when high collisional energies are util
101 of the reaction were further confirmed by a scrambling experiment, involving pillar[5]arene and per-
105 inferior temporal (IT) cortex to intact and scrambled faces that were filtered to selectively preser
106 , whereas face responsivity (neutral faces > scrambled faces) and face selectivity (neutral faces > n
107 longitudinally the responsiveness to faces, scrambled faces, and objects in macaque inferotemporal c
112 d that the peak was related to the disulfide scrambled forms and was isobaric with the correctly fold
113 g step, misfolded proteins such as disulfide scrambled forms can be formed, and purification steps ar
114 e complex, 5, was obtained through deuterium scrambling from eta(2)-D(2) in 2-d(2) into the methyl gr
115 the genetics by removing or recoding genes, scrambling gene order and replacing all non-coding DNA w
117 and modification by loxP-mediated evolution (SCRaMbLE) generates combinatorial genomic diversity thro
118 ncrypted genome architecture contains >3,500 scrambled genes, as well as >800 predicted germline-limi
120 This genome assembly provides a draft of a scrambled genome and a powerful model for studies of gen
121 ng disorder caused by defective phospholipid scrambling, has been associated with mutations in the TM
124 face-selective response is absent for phase-scrambled images and therefore not due to low-level info
125 en category correlations for both intact and scrambled images demonstrating distinct patterns of resp
129 rithms are utilized to convert the spatially scrambled images into fluorescent images and video.
131 However, the difference between intact and scrambled images was smaller in V3 compared to V1 and V2
132 ons are consistent with the lack of isotopic scrambling in C(16)O-(18)O(2)-(16)O(2) reactions, and wi
135 njected with EETI 2.5F proteins containing a scrambled integrin-binding sequence, demonstrating the i
136 e interaural level differences but presented scrambled interaural time differences with vocoded speec
139 is asymmetry by ATP-independent phospholipid scrambling is important in cellular signaling, but its m
141 A major consequence of Ca(2+)-dependent scrambling is the release of extracellular vesicles that
142 compare native cytotoxin 3 (CTX III) and its scrambled isomer, another category of protein mixture, f
143 cterized by cell shrinkage and cell membrane scrambling leading to phosphatidylserine (PS) externaliz
144 beta2-adrenergic and adenosine A2A receptors scramble lipids, suggesting that rhodopsin-like G protei
146 rovide a possible mechanism for phospholipid scrambling mediated by PLSCRs and the importance of PRD
147 hat target Foxp3 and IL-17, respectively, or scrambled miR (mock) or inhibitors confirmed that these
149 oint inactivation of beta- and gamma-catenin scrambles motor neuron settling position in the spinal c
150 more reliable for the intact movie than the scrambled movie, indicating that these regions accumulat
155 In contrast, neurons transfected with a scrambled nontargeting siRNA were indistinguishable from
158 lfide bond scrambling, and to understand why scrambling occurs, we determined the disulfide bond prof
159 tion of brain Galphai(2) proteins, but not a scrambled ODN, abolished the renal sympathoinhibitory re
161 ducts of deuterated retinol showed a lack of scrambling of a putative allylic radical at C-3 and C-4.
165 ements - result in a cancer genome that is a scrambling of intervals, or "blocks" of the germline gen
166 onversion of carbene and alkyne leads to the scrambling of labels over both alkynyl (sp) carbons.
168 e protein, is known to mediate bidirectional scrambling of phospholipids in a Ca(2+)-dependent manner
171 serve as channels facilitating the movement (scrambling) of phospholipids between leaflets of the mem
172 tubule cell lines compared with wild-type or scrambled oligonucleotide-treated cells, respectively.
173 ble for peptides that are prone to disulfide scrambling or are unstable in solution with partly reduc
175 gns and providing a new way to determine the scrambling patterns, which could be applied for those se
176 n, TAT-CBD3, but not CBD3 without TAT or TAT-scramble peptide, inhibited increases in cytosolic Ca(2+
177 espectively, whereas the third analogue is a scrambled peptide (Mel-SCR) that contains the amino acid
179 membrane-delineated cAMP (tau=251+/-51 s for scrambled peptide control vs. 399+/-79 s for Ht31).
185 ls (n = 12) were evenly split into pHBSP and scrambled peptide groups and injected daily (10 mug/kg p
190 the presence of EGF, Disruptin, but not the scrambled peptide, inhibits EGFR dimerization and causes
193 onclude that an engineered opsin monomer can scramble phospholipids, and that the lipid-exposed face
197 multigram scale-up route for highly soluble 'scrambled' porous cages prepared from a mixture of comme
200 whereas no tumor uptake was observed with a scrambled radiolabeled peptide (64)Cu-NO2A-GSG-DRD-RWSWW
201 est that the mixed dinuclear Pd(III) complex scrambles readily to give the two Pd(III) homodimers [Ac
202 tch are predictive of enhancer activity; (3) scrambling repressor motifs leads to aberrant reporter e
203 he design of negative controls by permitting scrambling, reversing, complementing or introducing mult
204 HSP27 short interfering RNA (siRNA) but not scrambled RNA disrupted this association and reduced the
206 e.g. OnRS/miR-124, OnRS/GFP-siRNA, OnRS/Neg (scrambled RNA) and OnRS/MGA (malachite green aptamer)) w
209 It catalyzes reduced RNase oxidation and scrambled RNase isomerization and insulin reduction and
210 ling responses were seen in the polarization-scrambling RPE layer, ranging from hyperproliferation to
211 hat the plasma membrane cell fate regulator, SCRAMBLED (SCM), is mislocalized in ugt80B1 mutants, und
212 ere identified by contrasting sentences with scrambled sentences, revealing a bilateral temporal lobe
213 th lentiviruses that expressed miR-26a1 or a scrambled sequence (control); proliferation and colony f
214 rgeting catenin beta 1 (CTNNB1; CTNNB1-LNP), scrambled sequence (Scr-LNP), or phosphate-buffered sali
215 plementary target sequence exceeds that of a scrambled sequence by nearly 3 orders of magnitude.
220 1, we overexpressed precursor miR-181c (or a scrambled sequence) in primary cultures of neonatal rat
223 cterial lung burden than mice treated with a scrambled-sequence PPMO or phosphate-buffered saline.
226 t with the prosthesis in the 'On', 'Off' or 'Scrambled' setting presented in a randomised order.
228 d with eIF5A shRNA was compared with that of scramble shRNA-transduced counterpart by the iTRAQ metho
229 aH2AX by H2O2 treatment (20 mum) subsided in scrambled shRNA but exacerbated in SelH shRNA MRC-5 cell
231 utathione level was lower in SelH shRNA than scrambled shRNA HeLa cells, and the H2O2-induced cell de
233 migrate faster than the ones expressing the scrambled shRNA on a collagen I gel (two-dimensional) al
234 pression did not change in similarly treated scrambled shRNA transgenic kidneys, and we observed no C
236 c mice that express stanniocalcin-1 shRNA or scrambled shRNA upon removal of a floxed reporter (phosp
237 lk1 knockouts, as well as with a fraction of scrambled shRNAs, suggesting a sequence-dependent but no
255 ied TMEM16-channel homologues do not mediate scrambling, suggesting that the family diverged into cha
257 act maps to detect rearrangements induced in SCRaMbLE (synthetic chromosome rearrangement and modific
259 ically, we created a series of truncated and scrambled tau constructs and characterized the size and
261 ssion of these factors and, thereby, lineage scrambling that is disconnected from TCR restriction by
265 ctions in disordered media are well-known to scramble the information content of light by complex but
266 ttering, in which multiple scattering events scramble the recorded electron diffraction intensities s
270 dex distribution of biological tissue, which scrambles the incident light and destroys the optical fo
271 Proteasomal targeting was verified by either scrambling the mODC-PEST motif, or via proteasomal inhib
273 n of an object at a particular location, but scrambling the timing of the spikes over one whisking cy
274 mplications of Ca(2+)-dependent phospholipid scrambling, the extracellular vesicles associated with t
275 -react with other amyloidogenic proteins and scrambling their grafted sequences eliminates antibody r
279 ents, regulators, and dialysis organizations scramble to keep up with the frequent release of wide-ra
282 Hep3B alpha3-positive, but not wild-type and scramble transfected, cells acquired protection by soraf
285 g only two heavy chains, generated much less scrambling under the same heat-stressed conditions.
287 ll proliferation compared with mock and pSV (scrambled vector) treatments, as determined by 5-bromo-2
290 ly support the mechanism of peptide sequence scrambling via b ion cyclization, and provide the first
291 range of nonvocal control sounds, including scrambled voices, environmental noises, and animal cries
294 butene cis-trans isomerization and H(2)/D(2) scrambling were shown to be catalyzed by MoS(2) and WS(2
296 teins and via TMEM16F-dependent phospholipid scrambling with an assistant role of mPTP formation.
299 ort that ZIP as well as its inactive analog, scrambled ZIP, induced a dose-dependent increase in spon
300 ort that ZIP as well as its inactive analog, scrambled ZIP, induced a dose-dependent increase in spon
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