ライフサイエンスコーパス: scratch

1 significantly worse than trees inferred from scratch.

2 effort than writing sequential programs from scratch.

3 ritating sensation that triggers a desire to scratch.

4 ive locomotion and decreasing during fictive scratch.

5 ations, current pipelines must be rerun from scratch.

6 ls recruitment and CCT in mice with a cornea scratch.

7 en of starting the construction process from scratch.

8 available, we do not try to bin contigs from scratch.

9 patients endorsed a history of cat or kitten scratch.

10 eory predicts herein enzymatic activity from scratch.

11 y stated, "There is pleasure when an itch is scratched.

12 shown previously for cat walking and turtle scratching.

13 fied during cat and human walking and turtle scratching.

14 studies of cat and human walking and turtle scratching.

15 n spinal neurons and prevented BA-stimulated scratching.

16 moval of a spatial constraint rather than by scratching.

17 hanges triggered by dry-skin-evoked itch and scratching.

18 hese mice selectively attenuated itch-evoked scratching.

19 ent increase in spontaneous and touch-evoked scratching.

20 RPR internalization and morphine-independent scratching.

21 mice scratched after observing a conspecific scratching.

22 l A1 (TRPA1) gene deletion blocks CQ-induced scratching.

23 ing are a peculiarity for motoneurons during scratching.

24 eviously shown for spinal motoneurons during scratching.

25 pothalamus of mice that displayed contagious scratching.

26 and the flexion components of locomotion and scratching.

27 ns (aggression, grooming, and play) and self-scratching (a proxy indicator of anxiety) at 11-14 month

28 subjected to tape stripping, a surrogate for scratching, a cardinal feature of AD.

29 prior training or reward, we found that mice scratched after observing a conspecific scratching.

30 How do you touch yourself, for instance, to scratch an itch?

31 If the DNA parts must be generated from scratch, an additional 2-5 d are necessary.

32 intrathecal injection of GRP led to intense scratching, an effect largely reduced by either GRPR ant

33 of water flushing, and after repeated knife scratch and sandpaper abrasion under 570 kPa.

34 sed conductance in spinal motoneurons during scratch and swim network activity.

35 h1-shRNA both enhanced in vitro migration in scratch and transwell migration assays.

36 parison of laser induce damage resistance of scratched and non-scratched fused silica surfaces after

37 used silica (e.g. photosensitive impurities, scratches and redeposited silica compounds) were mitigat

38 H1 receptor antagonist terfenadine prevented scratching and alloknesis evoked by histamine, but not 5

39 eurons receive intense synaptic input during scratching and behave like neurons in the hindlimb enlar

40 strated a substantial reduction of excessive scratching and dramatic resolution of skin lesions.

41 t displacement behaviour--activities such as scratching and face touching--represents an important st

42 rent from the previous findings in low speed scratching and high speed grinding, in which there is an

43 and compared the cerebral mechanism of self-scratching and its correlation with pleasurability in 10

44 mid-thoracic segments contribute to hindlimb scratching and may be part of a distributed motor networ

45 lts in an itchy phenotype with constant skin scratching and multi-organ inflammation.

46 w that IL-23 is released in human skin after scratching and polarizes human skin DCs to drive an IL-2

47 mice lacking HTR7 or TRPA1 displayed reduced scratching and skin lesion severity.

48 t others could use this relationship between scratching and stress as an indication of the animal's s

49 inal motoneurons during network activity for scratching and swimming in an ex vivo carapace-spinal co

50 t of motoneurons are distinctly different in scratching and swimming.

51 ctivity may be associated with the addictive scratching and/or neural hypersensitization.

52 ir water repellency after finger-wipe, knife-scratch, and even 40 abrasion cycles with sandpaper.

53 FN-alpha2b , or ribavirin using intradermal, scratch, and/or patch tests, as well as lymphocyte activ

54 he ocular surface in untreated (UT), corneal scratched, and EDE mice.

55 Coitus, biting, and scratching are transfer mechanisms for the two primary s

56 o address this issue, we use turtle hindlimb scratching as a model for fine motor control, since this

57 sought to validate and test the severity of scratching as an objective measure of itch (4-point ordi

58 aCaT keratinocytes measured by wound healing scratch assay and chemoattractant-induced Transwell migr

59 PRCP-depleted cells migrated less on scratch assay and murine PRCP(gt/gt) aortic segments had

60 hort hairpin RNA (shRNA), was evaluated in a scratch assay and transwell migration assay.

61 ression, enzymatic assay aromatase activity, scratch assay cell migration, immunocytochemistry alpha-

62 tection following CNS injury in an astrocyte scratch assay in vitro and a rat TBI model in vivo.

63 Migration was quantified using a scratch assay over 12 hours.

64 A keratinocyte monolayer scratch assay was used to assess re-epithelialization; w

65 d healing assay, also known as the "in vitro scratch assay" as a simple, versatile, and cost-effectiv

66 Many experiments, such as a scratch assay, never display this asymptotic behaviour,

67 ity and directional migration in a monolayer scratch assay.

68 keratinocyte monolayers in an in vitro wound scratch assay.

69 Cell motility was assessed using a scratch assay.

70 ivalents (EVPOME) and closure of an in vitro scratch assay.

71 in Ndst1-silenced lymphatic endothelia, and scratch-assay responses to VEGF-C and FGF-2 were reduced

72 reduced cell migration as determined by both scratch assays and trans-well cell migration assays.

73 Scratch assays evaluated the promigratory activity of LG

74 Migration capacity was assessed by scratch assays in time-lapse imaging.

75 In vitro scratch assays of primary cultures were used to evaluate

76 Scratch assays showed partial inhibition of MVS and zinc

77 f PKCalpha with DLG1 promotes wound healing; scratch assays using cells depleted of PKCalpha and/or D

78 ifferent in vitro cell proliferation assays, scratch assays, and measurement of the epidermal thickne

79 ion had no impact on wound healing in normal scratch assays, but after subjecting the cells to mechan

80 , quantitative real-time PCR, western blots, scratch assays, CCK-8 assays and tubule formation assays

81 lerates re-epithelialization of keratinocyte scratch assays, potentially via chemokine receptor pairs

82 rin and stimulate the migration of cells in "scratch assays," both activities of which were inhibited

83 of two human cancer cell lines in monolayer scratch assays.

84 The final width and depth of the residual scratch at the onset of chip formation measured vary fro

85 High pressure phases are absent from the scratch at the onset of either chip or crack formation.

86 4A domain of murine type XVII collagen begin scratching at age 2 months and then develop erosions, su

87 exion during flexion reflex, locomotion, and scratching based on evidence from studies of cat and hum

88 e, or endothelin-1) and recorded spontaneous scratching before and after drug administration.

89 n followed by wetting in macro-scale surface scratches beginning approximately 2% below the dew-point

90 mice lacking NAAA failed to develop edema or scratching behavior after challenge with DNFB, confirmin

91 ate the contribution of Mrgprs to SP-induced scratching behavior and activation of cultured dorsal ro

92 SP-induced scratching behavior and activation of cultured dorsal ro

93 Chronic BDL rats displayed enhanced scratching behavior and thermal hyperalgesia indicative

94 subpopulations of itch-responsive neurons to scratching behavior and thermal hypersensitivity.

95 cids and a TGR5-selective agonist stimulated scratching behavior by gastrin-releasing peptide- and op

96 te infiltration, and antihistamine-resistant scratching behavior in mice exposed to the haptens, oxaz

97 i.d.) administration of AYP elicited intense scratching behavior in mice, which was prevented by the

98 nduced calcium influx in DRG neurons and the scratching behavior in mice.

99 pport this novel concept based on attenuated scratching behavior in response to histaminergic (histam

100 nt thymic stromal lymphopoietin also induced scratching behavior in the specific pathogen-free NC/Tnd

101 Injection of recombinant TSLP also induced scratching behavior in the SPF NC/Tnd mice.

102 re defective in SP signaling, and SP-induced scratching behavior was abolished in Trpa1(-/-) mice.

103 Scratching behavior was also induced by the intrathecal

104 dermally injected into mice and itch-related scratching behavior was assessed.

105 In a murine itch model, ET-1-induced scratching behavior was substantially augmented by pharm

106 opeptides, activation of spinal neurons, and scratching behavior were studied using TRPA1 antagonists

107 In support of this concept we found that scratching behavior, evoked by direct intradermal activa

108 Combined studies of scratching behavior, patch-clamp recording, and Ca(2+) r

109 GRPR neurons in the SCN abolished contagious scratching behavior, which was recapitulated by chemogen

110 lockade or PI3Kgamma inhibition reversed the scratching behavior.

111 ns in the brainstem exhibit markedly reduced scratching behavior.

112 ng gastrin-releasing peptide (GRP)-dependent scratching behavior.

113 th hapten-induced cutaneous inflammation and scratching behavior.

114 ility, and heightened evoked and spontaneous scratching behavior.

115 Activation of SCN GRP/GRPR neurons evoked scratching behavior.

116 se mice led to significantly diminished itch-scratching behaviors and reduced TRPA1 expression in der

117 Here, we report that scratching behaviors induced by histamine-dependent and

118 lopment of lesions, HOCl reduced lesions and scratching behaviour to a similar extent as a positive c

119 The diminished scratching behaviour was confirmed by impaired response

120 (licking or wiping) and itch-like (biting or scratching) behaviours.

121 Scratching beneath the surface: Pt-M(3d)-Pt(111) (M(3d)

122 Severity of scratching best correlated with patient-reported global

123 he injection site elicited discrete hindlimb scratch bouts directed toward the stimulus.

124 ild-type mice were observed in the number of scratch bouts elicited by SLIGRL and histamine.

125 as well as midge allergen-challenge-induced scratch bouts, midge allergen-induced IL-13 and IL-4 pro

126 ce exhibited significantly fewer 5-HT-evoked scratching bouts compared with wild-type mice.

127 gel prevented the development of lesions and scratching bouts during the whole observation period.

128 hibited robust reversal of histamine-induced scratching bouts in mice.

129 ited by inadequate frequency and duration of scratching bouts required for contagious itch test.

130 nductance states are present not only during scratching but also during swimming.

131 imply that new structures are not built from scratch, but rather form by co-opting preexisting gene n

132 scharge at itch nerve terminals and bouts of scratching by about 50%.

133 ation induces neuronal hyperexcitability and scratching by unknown mechanisms.

134 Scratched corneas of female A/J mice were inoculated wit

135 ation of the animal's stress state, and thus scratching could potentially have social function.

136 efficiency remained above 93% even after 40 scratch cycles, and the materials could be reused with a

137 ombination of two measures of variability of scratch density, namely standard deviation and coefficie

138 xtensor activities underlying locomotion and scratching, even in the absence of brain inputs and move

139 a mouse model of chronic itch, we show that scratching evoked by impaired skin barrier is abolished

140 (+) neurons led to substantial reductions in scratching evoked by multiple pruritogens and occurring

141 Scratching evokes a rewarding and pleasurable sensation,

142 simpler molecular mechanisms, designed from scratch, exhibit the same range of behaviors?

143 c dermatitis and psoriasis, including robust scratching, extensive epidermal hyperplasia, and dramati

144 yer is formed at the topmost of the residual scratch, followed by the pristine crystalline lattice be

145 Scratching friction tests were conducted using a nano-in

146 nduce damage resistance of scratched and non-scratched fused silica surfaces after HF etching with hi

147 We performed scratch-hardness tests on hardened samples of class G ce

148 So far, such scratching has been seen as a by-product of physiologica

149 vere infections in humans after dog bites or scratches, has a lipopolysaccharide (LPS) (endotoxin) wi

150 agious behaviors such as yawning and itching/scratching have mirror-like properties and clearly defin

151 chronic nicotine characterized by increased scratching, head nods, and body shakes.

152 proteasome, and apoptosis either during cell scratch healing or ganciclovir-induced apoptosis.

153 Watching someone scratch himself can induce feelings of itchiness in the

154 upregulated in tape-stripped mouse skin and scratched human skin.

155 expressing, mitochondria-depleted cells from scratch in 23 d, as well as offer a variety of methods f

156 d the production of, and social responses to scratching in a group of free-ranging rhesus macaques (M

157 nels are required for generating spontaneous scratching in a mouse model of ACD induced by squaric ac

158 as investigated the cerebral activity during scratching in chronic itch patients and whether it diffe

159 A higher activity during scratching in chronic itch patients, versus healthy cont

160 cratching in normal mice observing excessive scratching in genetically modified demonstrator mice.

161 withdrawal (flexion reflex), locomotion, and scratching in limbed vertebrates.

162 Q) stimulates itch nerves and causes intense scratching in mice by activating the G-protein coupled r

163 vates MrgprC11 and evokes receptor-dependent scratching in mice.

164 gious itch occurs in mice based on imitative scratching in normal mice observing excessive scratching

165 e studies are needed to validate severity of scratching in other pruritic disease.

166 The bouts of scratching in response to CQ were not different between

167 ls of BAs, prevented exacerbated spontaneous scratching in TGR5 overexpressing mice.

168 ergic signaling not only reduced spontaneous scratching in the IL-31Tg mice but also dramatically res

169 signaling in vitro and reduced IL-31-induced scratching in vivo.

170 agonist significantly attenuated 5-HT-evoked scratching in vivo.

171 ction potentials in DRG neurons and elicited scratching in WT mice but not Tlr3(-/-) mice.

172 ring two fictive motor tasks (locomotion and scratch) in decerebrate cats.

173 3-drug combination regimen for children from scratch, independent of adult regimens, in <2 years.

174 Scratching-induced pleasurability significantly activate

175 hat this reward system has a crucial role in scratching-induced pleasurability.

176 subjected to tape stripping, a surrogate for scratching, induces an IL-22 response that drives epider

177 iR-124-3p inhibited neuronal inflammation in scratch-injured neurons.

178 miR-124-3p promoted neurite outgrowth after scratch injury, characterized by an increase on the numb

179 In primary astrocyte cultures, hypoxia and scratch injury-induced astrogliosis was attenuated by bo

180 corneal epithelial primary cultures through scratch injury.

181 omonas aeruginosa ulcerative keratitis after scratch injury.

182 Marks designating gingival recession were scratched into the anterior segments of the replicas.

183 n this study, a novel approach of high speed scratching is carried out on silicon (Si) wafers at nano

184 The scratching is conducted on a Si wafer of 150 mm diameter

185 Because scratching is highly specialized rhythmic behavior, it i

186 ation we feel and the relief that comes from scratching, is an evolutionary warning system and defens

187 [very prominent] based on the observation of scratching lesions).

188 e appearance of the first abundant arthropod scratch marks in Earth evolution.

189 Severity of scratching may be a useful endpoint in clinical trials a

190 P channels participate in pruritogen-induced scratching may involve sites of action other than the pr

191 form MOR1D is essential for morphine-induced scratching (MIS), whereas the isoform MOR1 is required o

192 The comparison of scratches morphology after static etching and high-frequ

193 CI1) in locusts that performed natural aimed scratching movements.

194 Intense synaptic transmission during scratch network activity increases conductance and induc

195 are functionally integrated in the hindlimb scratch network.

196 key spinal interneurons with locomotion and scratching networks across limbed vertebrates generally.

197 Histamine itself elicited bouts of scratching not associated with the mechanical stimulus,

198 We demonstrate that scratching of human skin and tape stripping of mouse ski

199 ed to a significant reduction in spontaneous scratching of the hapten-challenged nape of the neck of

200 d, the simplest way, offline introduction of scratched or cut pieces of strips into the IMS injection

201 gh-conductance state is a select feature for scratching or a property that goes with spinal motor net

202 ction independently, as in behaviors such as scratching or searching, or be used in coordinated patte

203 In contrast, the scratching persisted and skin lesions worsened over time

204 e mid-thoracic interneurons activated during scratching project descending axons toward the hindlimb

205 te of protein structure predictors at http://scratch.proteomics.ics.uci.edu.

206 te of protein structure predictors at http://scratch.proteomics.ics.uci.edu/

207 lable as part of the SCRATCH suite at http://scratch.proteomics.ics.uci.edu/.

208 ow environmental representations emerge from scratch provided a new window into the information proce

209 The itch-scratch reflex serves as a protective mechanism in every

210 In addition, there is no scratch related damage initiations found on the samples

211 Watching video clips of someone scratching (relative to control videos of tapping) activ

212 y performances that can be "engineered" from scratch, remain elusive.

213 y elastic moduli exceeding 20 GPa, excellent scratch resistance and flexibility, and very low oxygen

214 interface attachment with Cu, improving the scratch resistance and oxidation resistance of Cu.

215 , the low friction coefficient and excellent scratch resistance make them attractive as solid lubrica

216 tes mediate itch by evoking a Tgr5-dependent scratch response in mice.

217 ic acid (0.2 mol/L) pH-dependently induced a scratching response in mice when applied intradermally t

218 1, is involved in the acidic citrate-induced scratching response.

219 A1 and TRPV1 channels may be involved in the scratching responses to intradermal pruritogens, this is

220 ature cattle were injured by blunt impact or scratching, resulting in localized chondrocyte death.

221 id-thoracic segments leads to a weakening of scratch rhythmicity.

222 ming of (i.e., reset) cat walking and turtle scratching rhythms; in addition, reflex responses to leg

223 There was a significant decrease in scratching severity for patients experiencing itch impro

224 Patients experiencing improvement of scratching severity of 1 point or greater had significan

225 on reflex, multiple forms of locomotion, and scratching share key components.

226 croarray analysis of L. rhamnosus GG treated scratches showed increased expression of multiple genes

227 Severity of scratching showed responsiveness over time.

228 Scratching significantly attenuated the itch sensation (

229 Secondly, when macaques scratched, subsequent interactions were less likely to b

230 sol, but not stress-related behaviors (e.g., scratching), suggesting the possibility of some anxiolyt

231 CMAPpro is available as part of the SCRATCH suite at http://scratch.proteomics.ics.uci.edu/.

232 libraries and data are available through the SCRATCH suite of protein structure predictors at http://

233 ta and web servers are available through the SCRATCH suite of protein structure predictors at http://

234 ests were conducted using a nano-indentation-scratching system with the tip motion parallel or perpen

235 whereas cell motility was assessed using the scratch test and confocal microscopy.

236 ducibility and overall agreement between the scratch test and USG was moderate, with a spearman's rho

237 We conclude that the scratch test deserves further investigation.

238 The scratch test has very high reproducibility and overall a

239 , the two raters independently performed the scratch test on separate randomly selected patients (15

240 The scratch test uses auscultation to detect the lower liver

241 s outpatients were randomly selected and the scratch test was performed by two raters independently,

242 Agreement between raters on the scratch test was very high, with an intra-class correlat

243 phage migration by using Boyden chambers and scratch tests, characterized its contribution to experim

244 In nano-scratch tests, the TFMG coatings achieved a coefficient

245 in design is to build protein scaffolds from scratch that allow precise control over metal coordinati

246 ive science-centered information system from scratch that has been afforded by the Sidra Medical and

247 rs initially sought to design circuits "from scratch" that functioned as independently as possible fr

248 basic biological processes, but we have only scratched the surface of what they have to offer as rese

249 s have anti-bat strategies, and we have just scratched the surface.

250 Scratching the skin of healthy adults and tape stripping

251 elopment, has restricted researchers to only scratching the surface of this inherently challenging su

252 During fictive scratch, the amplitudes of DRPs and PADs evoked by both

253 Primary human keratinocyte monolayers were scratched then exposed to lysates of Lactobacillus (L) r

254 een noxious and pruritic pathways, and allow scratch to inhibit itch.

255 to almost every leg motion, from posture to scratching to locomotion.

256 rophysiologic reflexes, such as coughing and scratching, to expel invading pathogens and noxious envi

257 Scratching triggers skin flares in atopic dermatitis.

258 Scratching was attenuated in Tgr5-KO mice but exacerbate

259 Spontaneous scratching was exacerbated in transgenic mice that overe

260 Firstly, we found that the likelihood of scratching was greater around periods of heightened soci

261 Histamine- and touch-evoked scratching was inhibited by the mu-opiate antagonist nal

262 Touch-evoked scratching was observed following i.d. 5-HT (5-hydroxytr

263 In addition, no corneal scratching was observed using fluorescein stain.

264 d local symptoms in the absence of a bite or scratch were more common in patients with bat-acquired r

265 nd hyperactive behaviors such as jumping and scratching were recorded.

266 Primates (including humans) scratch when stressed.

267 methods, which recompute the hierarchy from scratch when the network topology changes, our method ad

268 Nppb triggered potent scratching when injected intrathecally in wild-type and

269 dently elicit the same degree of robust itch scratching, which can be inhibited by mu-opioid peptide

270 ide range of structures can be designed from scratch with atomic-level accuracy.

271 both beta-endorphin- and GRP-elicited robust scratching without affecting pain processing.

272 Scratch wound and proliferation assays revealed that cul

273 bladder cancer cell migration in a modified scratch wound assay and invasion through Matrigel.

274 In the scratch wound assay of cell spreading, HIF stabilization

275 A scratch wound assay, cell number count, and type I colla

276 Importantly, in vitro scratch wound assays demonstrate that the positive role

277 wth factor (HB-EGF) inhibits KC migration in scratch wound assays.

278 tions of AS II to assess cell proliferation, scratch wound closure, L-arginine uptake, cationic amino

279 corneas was performed in concert with linear scratch wound healing studies in primary and telomerase-

280 However, for claudin-1 effects on scratch wound healing were more pronounced when TJs coul

281 duced cell migration was evaluated by linear scratch wound healing, a cell migration assay, and live

282 xpression resulted in significantly impaired scratch wound healing, with delayed migration and reduce

283 An in vitro scratch wound initiated the release of thymic stromal ly

284 bit the motile behavior of melanoma cells in scratch wound, three-dimensional collagen-implanted sphe

285 Occludens-1, accelerated cell migration in a scratch wound-healing assay.

286 corneal epithelial cells following a linear scratch wound.

287 on through measurements of cell migration in scratch-wound assays.

288 Analysis of single-cell migration and scratch-wound closure clearly demonstrated that hERG1-ex

289 Cultured keratinocytes were scratch wounded and expression levels of the B2AR and ca

290 rast and NIMS images of phospholipids from a scratch-wounded cell monolayer were obtained.

291 Immunofluorescence analysis of scratch-wounded cells reveals that P2X7 inhibition resul

292 Accordingly, in a scratch-wounded epithelium, TGFbeta provokes cilium loss

293 njured paclitaxel-treated zebrafish skin and scratch-wounded human keratinocytes (HEK001) display red

294 Nucleotides released after scratch wounding activate purinergic receptors, leading

295 tic enzymes and release norepinephrine after scratch wounding.

296 The induction of cellular migration by scratch-wounding confluent cell cultures, culturing unde

297 en implicated, e.g., 2D cell migration after scratch-wounding, invasion of cancer cells, and finally,

298 ts on fibroblast cytoskeletal dynamics after scratch-wounding.

299 y of corneal epithelial cells to seal linear scratch wounds in a manner that was associated with a tr

300 less proliferative and failed to seal linear scratch wounds.