ライフサイエンスコーパス: screening method

1 ss the proposed method may be used as a fast screening method.

2 small interfering RNA-based synthetic lethal screening method.

3 es, identified by using a simple plate-based screening method.

4 ed high-throughput synthesis and biochemical screening method.

5 s a high-throughput BBB penetration oriented screening method.

6 e role for laxative-free CTC as an alternate screening method.

7 luate the effectiveness of this quantitative screening method.

8 enzymatic hydrolysis using a high-throughput screening method.

9 han and comparable specificity to the manual screening method.

10 , was discovered by fluorescence image-based screening method.

11 improve further the clinical utility of this screening method.

12 nteracting molecules by the yeast two-hybrid screening method.

13 ntropy can be designed via a high-throughput screening method.

14 esults in order to be used as a quantitative screening method.

15 vaccine effectiveness was assessed using the screening method.

16 n times may preclude its adoption as a rapid screening method.

17 medical significance to this high-throughput screening method.

18 c assay as a new approach in high-throughput screening method.

19 and mass spectrometry-based high-throughput screening methods.

20 traits difficult to analyze by other genetic screening methods.

21 assembly as well as to afford rapid in vivo screening methods.

22 implementable alternative to direct on-line screening methods.

23 assays are commonly used in high-throughput screening methods.

24 ated the performance characteristics of both screening methods.

25 subtypes with greater efficacy than isolated screening methods.

26 response, is a new approach to develop such screening methods.

27 ompared to wild type, thereby validating the screening methods.

28 evaluations, as an improvement over current screening methods.

29 entified mainly in an empirical manner using screening methods.

30 azetidinone CB1 antagonists by using virtual screening methods.

31 logical advances that will extend RNAi-based screening methods.

32 been a substantial push for new multianalyte screening methods.

33 ut has been limited by the lack of efficient screening methods.

34 there is a clear need to identify efficient screening methods.

35 velopment of improved functional metagenomic screening methods.

36 used to complement classical analysis and as screening methods.

37 s on animals; hence requiring new predictive screening methods.

38 ing intervals across the different available screening methods.

39 tes is hampered by a lack of reverse genetic screening methods.

40 are identifiable through existing amblyopia screening methods.

41 The substrate activity screening method, a substrate-based fragment identificat

42 infusion mass spectrometry (MS)-based glycan screening method acquires data on a millisecond time sca

43 Modern high-throughput screening methods allow researchers to generate large da

44 a powerful functional and chemical genomics screening method and provide guidelines for designing ef

45 difficulties is unclear and the appropriate screening method and subsequent management is the subjec

46 Using both the biosensor based screening method and the in vitro biological assay, the

47 to achieve with conventional forward genetic screening methods and mammalian cell cultures.

48 In contrast to traditional screening methods and mammalian models, this facile, tim

49 e development of protein-protein interaction screening methods and offers new perspectives on protein

50 el interactions and recently developed toxin screening methods and practical applications of engineer

51 estigated the utility of several noninvasive screening methods and the propagation of new treatments

52 ectiveness of 2 population-based skin cancer screening methods and to assess their budget effect and

53 ectiveness of 2 population-based skin cancer screening methods and to assess their budget effect and

54 lysis are a high mutation rate, an efficient screening method, and a trait with high heritability.

55 mproved sensitivity over all tested antibody screening methods, and detected antibody in 7 of 19 spec

56 ersies surrounding the use of different PROP screening methods are addressed.

57 those for other chronic diseases; effective screening methods are available for only a few cancers.

58 Conventional screening methods are based on different technologies, m

59 Such comprehensive screening methods are essential to define the concerted

60 enzymes by engineering approaches, suitable screening methods are necessary.

61 More efficient, quantitative high-throughput screening methods are needed to guide the optimization o

62 A), effective computational and experimental screening methods are not currently known for this speci

63 nt of infection prevention programs, yet few screening methods are published.

64 Screening methods are the first step in the control of a

65 Rapid and inexpensive screening methods are utilized when molecular methods ar

66 fections proved to be helpful as a secondary screening method, as opposed to the more traditional com

67 yet there are no reliable noninvasive early screening methods available.

68 ere analyzed initially by an anticancer drug-screening method based on a sulforhodamine B assay.

69 Employing a sequential screening method based on antibiotic sensitivity, RFLP p

70 We describe a novel quantitative viral screening method based on single-molecule detection that

71 Here, we report the use of a screening method based on the Gutzeit methodology to det

72 In this study, we use screening methods based on wide scope solvent extraction

73 regression was used to assess the effect of screening method, breast density, patient age, and cance

74 we developed an efficient combinatorial drug screening method called the Feedback System Control (FSC

75 Fragment-based screening methods can be used to discover novel active s

76 Current screening methods can only be used to disrupt a gene or

77 rk presents a sensitive and easily performed screening method capable of detecting AZAs at concentrat

78 ction immunoassay provides an easy and rapid screening method capable of detecting simultaneously in

79 Virtual screening methods combined with experimental assays were

80 High throughput screening methods combined with literature curation are

81 An screening method, comprised of straightforward sample tr

82 non-invasive, inexpensive, easily accessible screening method could be useful in both clinical and re

83 This screening method could be widely used to detect numerous

84 An FT-IR screening method coupled to data analysis using chemomet

85 Epigenome-wide screening methods cover an increasing number of CpG site

86 In this work, a screening method covering 116 human and veterinary drugs

87 We have developed a virtual ligand screening method designed to help assign enzymatic funct

88 ased immunoassay is suitable to be used as a screening method, detecting saxitoxin from 260 to 2360 m

89 Current blood bank screening methods do not identify infected donors, and B

90 asive cervical carcinoma was similar between screening methods during the first 2.5 years of follow-u

91 no-, micro- and mesoscales to random library screening methods (e.g. phage display), in vitro cellula

92 logy who are not identified with traditional screening methods (eg, CIA-positive, rapid plasma regain

93 here were differences in the microbiological screening methods employed, the individual clinical risk

94 A1, we made use of a rapid, high-throughput screening method exploiting laser-induced uncaging of gl

95 ing at age 40 versus 50 years with different screening methods (film, digital) and screening interval

96 Screening methods focusing solely on brightness or wavel

97 High-concentration biophysical screening methods followed by high-throughput crystallog

98 Using an in vivo screening method following the simultaneous randomizatio

99 otential of SERS application as a diagnostic screening method, following further validation and optim

100 ital breast tomosynthesis (DBT) as a primary screening method for breast cancer.

101 has been established as the primary imaging screening method for breast cancer; however, the sensiti

102 We have developed an on-line screening method for CB1 and CB2 ligands, where cellular

103 Single digital FOBT is a poor screening method for colorectal neoplasia and cannot be

104 lomere length is a sensitive but nonspecific screening method for DC.

105 ved the biosensor capability to be used as a screening method for detection of carbamate drugs in was

106 before CONDOR can replace pDUS as a reliable screening method for detection of eHAT.

107 s discovered using a glycan microarray-based screening method for detection of substrate specificitie

108 magnetic resonance (NMR) spectroscopy-based screening method for determining the use of two widely a

109 graphy as an easy, rapid and non-destructive screening method for evaluating large population trials

110 stem that could be used as a high throughput screening method for finding new alpha-synuclein anti-ag

111 e challenge test (OGCT) is a widely accepted screening method for gestational diabetes mellitus (GDM)

112 copy could offer a rapid and high-throughput screening method for identification of Leptospermum hone

113 This profile could provide a zero-cost screening method for identification of mecC-positive MRS

114 This provides a simplified screening method for identifying genetic or environmenta

115 chodilators provides an efficient cell-based screening method for identifying potent dilators from am

116 A simple screening method for isolation and determination of the

117 Ultrasound can be used as a screening method for malrotation eliminating the need fo

118 onsidered suitable for health authorities as screening method for MCs and to optimize frequency of sa

119 gh Resolution Melting (HRM) application as a screening method for must and wine authenticity.

120 d be used in a manner similar to the testing/screening method for neural tube defects and common chro

121 It also may serve as the basis for a simple screening method for new enzyme inhibitors for disease t

122 We developed a screening method for orphan receptor ligands, in which c

123 The sandwich ELISA can be a viable screening method for OVTXs detection in monitoring progr

124 od nowadays, a sensitive, accurate and rapid screening method for potential food allergens has become

125 we have developed a high-throughput library screening method for quantifying stability changes, whic

126 posed method can be recommended as a routine screening method for quantitation of sulfonamides in mil

127 s great potential as a qualitative molecular screening method for resource-limited settings when comb

128 A screening method for six biomarkers from polycyclic arom

129 In the present contribution, an automated screening method for studying ligand interactions of sel

130 ent a fast, sensitive, reliable and low-cost screening method for the authentication of processed com

131 essed the performance of pulse oximetry as a screening method for the detection of critical congenita

132 Currently there is a need for a rapid screening method for the detection of veterinary drugs i

133 We invented a high-throughput screening method for the examination of radioprotective

134 development of a high resolution melt (HRM) screening method for the identification of eight common

135 The aim of this study was to develop a screening method for the identification of novel modulat

136 A novel, fast, and sensitive screening method for the identification of the two most

137 spot assay has been widely used as a general screening method for the quantification and characteriza

138 This paper proposed a new screening method for the simultaneous detection of five

139 ed with the patch-clamp, an equally powerful screening method for the transport of uncharged compound

140 deficits underlying TBI as well as a useful screening method for therapeutic drugs.

141 ort routine clinical breast examination as a screening method for women at average risk.

142 The research on fast screening methods for antibodies against zoonotic pathog

143 l need for high fidelity and high-throughput screening methods for cell surface interactions.

144 significant opportunity to develop practical screening methods for complex formulations.

145 Moreover, screening methods for cutaneous therapeutics require acc

146 This study compares three screening methods for detecting GISA and hGISA strains i

147 Consequently, screening methods for duplication of FAD3 orthologues in

148 hallenge that would benefit from advances in screening methods for early detection that are rapid and

149 development of cost-effective toxicological screening methods for engineered nanomaterials.

150 The method was adapted for high-throughput screening methods for enzymology and drug discovery.

151 nsity of the pre-frying oil are suggested as screening methods for estimating the MCPD-E and G-E cont

152 We consider 7 single-step and modular screening methods for identifying G-E interaction at a g

153 rams, yet the lack of robust high-throughput screening methods for large libraries of enzyme variants

154 ere is a need for facile and high-throughput screening methods for monitoring programs.

155 e, sensitive, quantitative, and mobile rapid screening methods for pathogenic organisms are not yet r

156 xpression can complement traditional genetic screening methods for the identification of genes essent

157 Here we develop high-content phenotypic screening methods for the systematic identification of m

158 laboratory validation of this immunological screening method, for this complex group of toxins with

159 A simple high-throughput solid-phase screening method has also been developed to identify PAL

160 In the present study, a rapid screening method has been developed for the direct surfa

161 tography-tandem mass spectrometry (LC-MS/MS) screening method has been developed targeting 23 pharmac

162 With regard to diagnosis, a new screening method has been developed that allows predicti

163 A rapid screening method has been developed to determine binding

164 A mix and measure fluorescent screening method has been developed, that utilizes multi

165 re for the first time, a new, easy and rapid screening method has been used to investigate the DNA da

166 In addition, the screening method has the potential to provide the malari

167 s progress in high-throughput small molecule-screening methods has facilitated the rapid expansion of

168 However, the performance of different screening methods has not been studied.

169 In addition, new screening methods have been designed to select for speci

170 These findings suggest that both Etest screening methods have excellent NPV, but positive resul

171 However, assessments of novel screening methods have generally failed to distinguish b

172 o discover such molecules by high-throughput screening methods have utilized, as a read-out, a single

173 industry-standard preclinical cardiotoxicity screening methods, identify the effects of well-characte

174 Noncathartic CT colonography is an effective screening method in first-degree relatives of patients w

175 atologists, LDS is an acceptable alternative screening method in health care systems with limited bud

176 sive; hence, it is suggested to be used as a screening method in the field for preselection of rice w

177 momentum as a potential primary colon cancer screening method in the USA.

178 n neoplasms and is better than current stool screening methods in detecting those with advanced adeno

179 emands, other issues associated with labeled screening methods include signal interference that can a

180 Using high-throughput screening methods, including computational docking studi

181 We recommend colonoscopy as the preferred screening method, initiation of screening at age 40 year

182 ed for favorable harm-benefit ratios vary by screening method, interval, and outcome measure.

183 A mass spectrometry screening method is available to detect the addition of

184 This screening method is based on measurements of immunoglobu

185 The screening method is demonstrated for both ammonia lyases

186 A single-cell drug screening method is described that produces rich single-

187 A rapid, sensitive, and specific screening method is needed for in-field or bedside testi

188 The development of this single-cell drug screening method is presented, and fluorescent and stati

189 d on UV-VIS spectroscopy and chemometrics, a screening method is proposed to quickly screening some c

190 The most readily available supplemental screening method is ultrasonography, but little is known

191 This screening method is using a database of over 600 metabol

192 The development of improved breast cancer screening methods is hindered by a lack of cancer-specif

193 The accuracy of various screening methods is variable throughout the literature.

194 Current screening methods lack sensitivity, specificity, and hav

195 e of pesticides in soil, a multiple-compound screening method (log Kow 1.7-5.5) was developed based o

196 We compared the performance of two Etest screening methods (macromethod [MAC] and glycopeptide re

197 Using this screening method, mature leaves from fully developed pla

198 n we have combined an underutilized fragment screening method, native state mass spectrometry, togeth

199 Therefore, an alternative screening method, not directly based on the structure bu

200 A limitation of the conventional biomarker-screening method of enzyme-linked immunosorbent assay (E

201 We have developed a screening method of identifying the 'master regulator' t

202 a promising and viable approach for a green screening method of phenolic compounds in EVOO, by means

203 Using the orthogonal fragment screening methods of native state mass spectrometry and

204 ul tool to assess the performance of virtual screening methods on NRs, to assist the understanding of

205 Thus, a complete recessive carrier screening method or diagnostic test should detect CNV al

206 the recommended age of screening initiation, screening method, preparation, and the interval for repe

207 This protocol covers the docking and virtual screening methods provided by the AutoDock suite of prog

208 rlap score (xLOS), a 3D ligand-based virtual screening method recently developed in our group, to sel

209 ded to identify the biological processes and screening methods relevant for other common diseases.

210 This study demonstrates the success of the screening method resulting in a powerful lysin with pote

211 Screening methods should be simple, quick, inexpensive a

212 By utilizing this double-layer screening method, six positive mutants were obtained fro

213 f death from colorectal cancer indicate that screening methods such as colonoscopy have a positive im

214 The future implementation of early screening methods such as exhaled breath condensate anal

215 ogether with two proven and popular fragment screening methods, surface plasmon resonance and X-ray c

216 We report a high-throughput screening method that allows diverse genotypes and corre

217 provides a sensitive, rapid, and noninvasive screening method that can be used for imaging and quanti

218 Here, we present a screening method that comprehensively explores the param

219 des a rapid, sensitive, and easily performed screening method that could be multiplexed for the simul

220 and validity data on a brief neurocognitive screening method that could be used to routinely screen

221 Since MLVA is a high-throughput screening method that is fairly inexpensive, easy to per

222 Here, we report a screening method that probes over 3,000,000 combinations

223 veloped a broadly applicable high-throughput screening method that simultaneously identifies multiple

224 We present a novel screening method that utilized 144 additive conditions t

225 thus a need for inexpensive and non-invasive screening methods that are able to accurately estimate b

226 g novel chemopreventatives, therapeutics and screening methods that are not possible with cultured ce

227 ation networks facilitate network based gene screening methods that can be used to identify candidate

228 evelopment has been aided by high throughput screening methods that detect compound effects on a sing

229 Therefore, screening methods that help to rapidly identify activato

230 Screening methods that use traditional genomic, transcri

231 ntially following the introduction of breast-screening methods, the clinical significance of early de

232 he review focused on resting ABI as the sole screening method; the diagnostic performance of ABI test

233 ass spectrometry as a complementary fragment screening method to accelerate drug discovery.

234 Hence, vMALDI-LIT/MS can be used as a rapid screening method to complement the traditional GC/MS and

235 The concept of using pulse oximetry as a screening method to detect undiagnosed critical congenit

236 this quantitative method is very useful as a screening method to determine gelatin from various sourc

237 d a polyacrylamide gel electrophoresis-based screening method to determine topological effects of het

238 light mass spectrometry (MALDI-TOF MS)-based screening method to discover natural products that modif

239 DTS is a simple screening method to discover novel viral nucleic acids.

240 -energy searches, which provide an in silico screening method to evaluate candidate molecular buildin

241 an spectroscopy has been explored as a quick screening method to evaluate the presence of lactose and

242 We used insertional mutagenesis to develop a screening method to generate null alleles in a human cel

243 previously undescribed flow cytometry-based screening method to identify bacterial genes expressed i

244 ary, we developed an in vivo Drosophila RNAi screening method to identify flow-sensitive genes that r

245 on and has been adapted as a high-throughput screening method to identify genes involved in essential

246 study established a novel, simple and quick screening method to identify gRNA candidates for targeti

247 roblasts, thus validating the ability of the screening method to identify intracellular replication-d

248 fluorimetry (DSF) is a rapid and inexpensive screening method to identify low-molecular-weight ligand

249 yme-linked immunosorbent assay (ELISA)-based screening method to identify mutants from a transposon i

250 Here we developed a high throughput screening method to identify mutants of 6-phosphoglucona

251 Here we describe a screening method to identify mutations that have a criti

252 otential of this cell-based, high-throughput screening method to identify novel radiosensitizers and

253 Therefore, we have developed a new screening method to identify novel substrates for DNA po

254 holds potential to be further developed as a screening method to identify pathogen-specific recogniti

255 In this study, we use a screening method to identify that two miRNAs (miR-25 and

256 pression technology (RIVET) and used it as a screening method to identify Vibrio cholerae genes that

257 ection model provides a valuable preclinical screening method to investigate cutaneous immune respons

258 try (DSF) as an inexpensive, high throughput screening method to investigate the folding of silk prot

259 mulation in seed, we have developed a simple screening method to isolate Arabidopsis seed oil mutants

260 as a simple and generic biophysical fragment screening method to reproduce assessments from NMR-based

261 e first stage, we use a Bayesian independent screening method to select the most promising SNPs.

262 ht to investigate the ability of whole-exome screening methods to detect disease-causing variants in

263 r study evaluated two susceptibility testing screening methods to detect mupirocin high-level resista

264 Two screening methods to detect staphylococcal colonization

265 emia, sample availability is very scarce and screening methods to diagnose the illness are not common

266 We applied high-content screening methods to monitor B-cell activation on the ce

267 High-quality screening methods to prioritize homes for monitoring and

268 cal production cell lines requires efficient screening methods to select the host cell line and final

269 The three screening methods used were brain heart infusion agar wi

270 e report a novel PTK activity and inhibition screening method using hydrogel-immobilized peptide subs

271 used to develop and optimize a HRMS suspect screening method using only the exact mass as a priori i

272 Here we present a genetic screening method using photo-highlighting for candidate

273 The novel screening method using sterile sponges was easy to perfo

274 Here, we present novel screening methods using an electrochemical chip coupled

275 required to implement comprehensive suspect screening methods using high-resolution mass spectrometr

276 Here, we describe a high-throughput screening method utilizing error-prone PCR and next-gene

277 ng tandem mass spectrometry (wide-SIM/MS(2)) screening method utilizing ultraperformance-LC nanoelect

278 An efficient screening method was developed for functionalized DNA-ta

279 A four-step screening method was employed to search for the lowest-e

280 This screening method was first applied to the dpiB gene from

281 A random PCR-based molecular screening method was used to identify the infectious age

282 Using MeDIP-chip, a methylation microarray screening method, we found that 0.5% (120 loci) of human

283 Using a high-throughput screening method, we have identified several compounds t

284 Using our screening method, we have identified small molecules tha

285 Applying our screening method, we identified 51 lncRNAs that can posi

286 Using a differential whole-proteome screening method, we identified Plasmodium falciparum sc

287 Here, by using in silico drug-screening methods, we discovered that Celastrol, a penta

288 Using these orthogonal screening methods, we identified drugs that restored the

289 apting translation assays to high-throughput screening methods, we showed that null yeast strains har

290 n value, sensitivity and specificity of this screening method were established through ROC analysis.

291 past 10 years, as cell-based high-throughput screening methods were applied, together with large chem

292 e allowed for the development of nontargeted screening methods, where data sets can be archived and r

293 The change in color offers a fast pre-screening method, whereas monitoring via SERS is used fo

294 This screening method will expedite the discovery of drug tar

295 ed for large-scale use, this high-throughput screening method will facilitate rapid screening of nano

296 technology is a promising and feasible mass-screening method with reasonable sensitivity for detecti

297 his work, we demonstrate the validity of the screening method with the commercial laccase from the fu

298 We argue that combining multiple diagnostic screening methods with multivariate logistic regression

299 e combination of pharmacophore-based virtual screening methods with radioactive methylation assays pr

300 Nontargeted screening methods with ultrahigh-performance liquid chro