ライフサイエンスコーパス: sebum

1 icrobial action of free fatty acids in human sebum.

2 he sebaceous gland responsible for producing sebum.

3 l therapy, no agents are available to reduce sebum.

4 ith a significant role in the composition of sebum.

5 PCNA, and correspondingly high production of sebum.

6 ecretes a unique mixture of lipids, known as sebum.

7 ple treatments caused greater suppression of sebum.

8 arget given its central role in formation of sebum, a key factor in acne pathogenesis.

9 As a way to reduce sebum and its interference with the process of follicula

10 nt to effective antimicrobial penetration in sebum and selective antimicrobial action in the skin are

11 ed from a coacervate vehicle into artificial sebum and the coacervate's composition and properties.

12 d, with the sebocytes producing little or no sebum and undergoing abnormal cornification.

13 of entrained agents from the coacervate into sebum and, consequently, higher bioavailability on the s

14 ate is the most abundant fatty acid in human sebum, and among hair-bearing animals is restricted to h

15 consisting of desquamated keratinocytes and sebum, are central to its pathogenesis.

16 which naturally accumulate in epidermis and sebum, as autoantigens presented by CD1a.

17 sebum production, because over 80% of human sebum components contain fatty acids.

18 , through a variety of cellulosic coacervate/sebum composite barriers prepared on cell culture insert

19 lterations in sebaceous gland activation and sebum composition.

20 Moreover, gender-related differences in sebum content are not associated with altered SC hydrati

21 significant for SC glycerol content than for sebum content.

22 onsteroidal androgen receptor antagonist for sebum control and treatment of androgenetic alopecia.

23 Overproduction of sebum, especially during adolescence, is causally relate

24 Sebum excretion rate and auto-fluorescence from follicul

25 Medical therapies that reduce sebum excretion result in clinical improvement of acne.

26 Sebum excretion was eliminated for several weeks, and de

27 In this study, we examined the effects of sebum FFAs on the antimicrobial peptide (AMP)-mediated i

28 These data suggest that sebum FFAs upregulate the expression of hBD-2 in human s

29 Various sebum free fatty acids (FFAs) have shown antibacterial a

30 Sebum from these mice contained a reduced level of type

31 We assessed here whether sebum influences stratum corneum hydration or permeabili

32 irst insights into a potential link of lower sebum levels and lipid content and thus reduced skin moi

33 ion and is EGFR dependent, as gland size and sebum levels return to normal values after crossing to t

34 Although a mixture of synthetic, sebum-like lipids (sterol/wax esters, triglycerides) did

35 well as in the formation and composition of sebum, likely by regulating the trafficking of fatty aci

36 level of type II diester wax, a major mouse sebum lipid species, and showed perturbations in mass sp

37 atty acids necessary for proper synthesis of sebum lipids.

38 ndicates that an additional component of the sebum may be required to improve bacterial clearance.

39 Sebum on the skin surface was naturally fluorescent and

40 cooling damaged sebaceous glands and reduced sebum output for 2 weeks, with minimal injury to surroun

41 TrueMass Sebum Panel analyses showed a reduction in saturated and

42 nes or fibrates had significant increases in sebum production (37 and 77%, respectively) when compare

43 lands in mature mice, leading to exacerbated sebum production and accumulation on the skin surface.

44 flake homozygotes show reduced sebum production and are unable to synthesize the monoun

45 nd could be a desirable approach to reducing sebum production and improving acne.

46 sites, and SC hydration correlates with both sebum production and SC glycerol content, but the correl

47 of melanocortins in the regulation of human sebum production and support the use of the rat preputia

48 ndicate that PPARs play a role in regulating sebum production and that selective modulation of their

49 abolizing enzymes is important in regulating sebum production because these enzymes can convert weak

50 for melanocortins in the modulation of human sebum production has not been established.

51 and to assess the effects of PPAR ligands on sebum production in patients.

52 asing our understanding of the regulation of sebum production is a milestone in identifying alternati

53 Excess sebum production is an integral part of disease pathogen

54 Understanding the factors that regulate sebum production is important in identifying therapeutic

55 Sebum production is key in the pathophysiology of acne,

56 Sebum production is regulated by the opposing effects of

57 enzonit rile (1), for the topical control of sebum production is reported.

58 Sebaceous gland size and sebum production may serve as biomarkers for EDAR stimul

59 (13-cis RA)) is the most potent inhibitor of sebum production, a key component in the pathophysiology

60 it resulting from androgen-induced increased sebum production, altered keratinisation, inflammation,

61 strength, sexual function, prostate volume, sebum production, and hematocrit and lipid levels did no

62 strength, sexual function, prostate volume, sebum production, and hematocrit and lipid levels.

63 ma (PPARgamma), a potential cause of reduced sebum production, as well as the potential involvement o

64 s glands is designed to substantially affect sebum production, because over 80% of human sebum compon

65 sebaceous gland differentiation with reduced sebum production, chronic inflammation, and ultimately t

66 linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratini

67 the contribution of each receptor subtype to sebum production, lipogenesis assays were performed in S

68 ocytes results in enlarged SGs and increased sebum production.

69 crine glands, including a marked decrease in sebum production.

70 may account for the regional differences in sebum production; (iii) to compare the activity of 17bet

71 ied in both Eda mutant and wild-type mice by sebum secretion to levels higher than those observed in

72 ereas the gland's main function-excretion of sebum via the holocrine mechanism-can only be evaluated

73 decrease in squalene levels, a biomarker for sebum, was observed.