ライフサイエンスコーパス: secondary

1 undles did not reach the orbit, resulting in secondary aberrant misinnervation of the lateral rectus

2 ine coupling stoichiometries of electrogenic secondary active transporters reconstituted in proteolip

3 li has become the paradigm for this class of secondary active transporters.

4 n-based RIC with MAC in patients with MDS or secondary acute myeloid leukemia.

5 ding bile acid sequestrants only as optional secondary agents for consideration in patients intoleran

6 A hydrogen borrowing reaction employing secondary alcohols and Ph* (Me5C6) ketones to give beta-

7 mination of the alkene with simple exogenous secondary amines under extraordinarily mild reaction con

8 ch for the alpha-functionalization of cyclic secondary amines.

9 or the facile transfer of primary (-NH2) and secondary amino groups (-NHR) to heteroaryl- as well as

10 For secondary amino ozonides, additional functional groups h

11 releukemia, low-risk MDS, high-risk MDS, and secondary AML.

12 Other secondary analyses confirmed these results.

13 We did our primary and secondary analyses in the per-protocol set, which exclud

14 Secondary analyses showed significantly greater likeliho

15 e proceeding to complicated, time consuming, secondary analyses.

16 In a prespecified secondary analysis designed to address the relationship

17 A secondary analysis loop in EoE patients defined an IGHE

18 This was a preplanned secondary analysis of a prospective cohort enrolled from

19 Secondary analysis of data from the prospective randomiz

20 ingle-center, prospective cohort, as well as secondary analysis of existing transcriptomic and proteo

21 Secondary analysis of prospective data from the Randomiz

22 The authors performed a secondary analysis of the RIVER-PCI (Ranolazine in Patie

23 This prespecified secondary analysis shows that, when added to usual care,

24 s who had received pneumococcal vaccination (secondary analysis).

25 In a prespecified secondary analysis, no difference in mortality was found

26 important limitation of this study since the secondary and sensitivity analyses results were inconsis

27 at -78 degrees C in the presence of primary, secondary and tertiary alcohols affords the correspondin

28 bed herein allows the construction of stable secondary and tertiary amine-linked protein conjugates w

29 vation which promotes the alpha-cyanation of secondary and tertiary amines using magnetic nano-ferrit

30 The coupling of ortho- and para-phenols with secondary and tertiary boronic esters has been explored.

31 relays on intracellular events amplified by secondary and tertiary messenger molecules.

32 entary site selectivities in the addition of secondary and tertiary radicals to pyidinium salts are d

33 766244 children attending Scottish primary, secondary, and special schools at any point between Sept

34 Nonstabilized primary, secondary, and tertiary radicals can be used to install

35 munized mice promptly produced a more potent secondary anti-RABV neutralizing antibody response than

36 We present the coupling of primary and secondary benzyl alcohols with indoles to form 3-benzyla

37 ved a changed preference for a low-affinity, secondary binding motif.

38 include compounds that link the primary and secondary binding sites.

39 mal hydrogen bonds of type YH-X analogous to secondary bonding.

40 stituted benzylamines gave the corresponding secondary boronic esters with high ee.

41 Instead of the secondary C-H bond, the new catalyst is capable of preci

42 e (MR) imaging in the detection of index and secondary cancers in women with newly diagnosed breast c

43 ng local solution saturation with respect to secondary carbonates.

44 , randomised withdrawal phase 2a trial in 25 secondary care centres in Denmark, Estonia, France, Germ

45 ial features of GICs in order to prevent the secondary caries.

46 ring oil palm plantations triggered powerful secondary 'cascading' effects on natural habitats locate

47 inical and laboratory evaluations to exclude secondary causes of disease.

48 tion of microglia and increase reactivity to secondary challenges.

49 From these, the secondary chemical screen identified SETD8, the H4(K20me

50 Secondary clinical outcomes demonstrated no significant

51 Secondary clinical outcomes included organ-specific symp

52 ocol population (n=58), the primary and most secondary clinical outcomes significantly favoured MT (a

53 ed primary sludge and its reuse potential as secondary coagulant were investigated.

54 ER stress, and defective cell morphology are secondary consequences of bulky cargo retention.

55 sorting (ILS) and/or introgression following secondary contact.

56 ithin-estuary mixing and supply of reworked, secondary contamination from erosion of anthropogenicall

57 roposed Arg-His cation-pi interaction in the secondary coordination sphere of the outermost, "distal"

58 can distinguish ZIKV with previous DENV and secondary DENV infections with a sensitivity of 87.5% an

59 Secondary disorders of erythrocyte hydration include sic

60 Secondary diversification occurs when Ig V regions under

61 Secondary DNA structures are uniquely poised as therapeu

62 ng RNAs (ncRNAs) could stabilize deleterious secondary DNA structures, noncoding RNA associated DNA/R

63 tor and sensory function is primary cause or secondary effect of abnormal body weight is uncertain.

64 Secondary effects on protein folding homeostasis likely

65 By implementing this method in secondary electron (SE) microscopy, a SE spectrum (white

66 val [CI], 0.79 to 0.92; P<0.001) and the key secondary end point (816 [5.9%] vs. 1013 [7.4%]; hazard

67 None of the secondary end point or day-30 all-cause mortality or hea

68 ontrast-associated acute kidney injury was a secondary end point.

69 y end point and overall survival (OS) as the secondary end point.

70 sed for the second primary end point and the secondary end points in the final analysis.

71 Secondary end points included anatomic patency, adverse

72 Secondary end points included cardiac magnetic resonance

73 Secondary end points included change in body weight and

74 Secondary end points included clinical outcomes (major a

75 Secondary end points included disease-free survival and

76 Secondary end points included intraoperative and postope

77 The primary end point was PFS; secondary end points included overall survival (OS), obj

78 Secondary end points included overall survival and subgr

79 Secondary end points included overall survival, distant

80 Secondary end points included repeat revascularization a

81 The secondary end points included short-term weight loss, se

82 Secondary end points included the proportion of patients

83 Secondary end points were a 50% or greater reduction in

84 Secondary end points were change in 6-minute walk distan

85 Main secondary end points were overall survival and bronchiol

86 Secondary end points were the change in the mean number

87 Secondary end points were the number of telephone calls

88 lso did not significantly improve any of the secondary end points.

89 Efficacy and pharmacodynamics were secondary end points.

90 sion-free survival and overall survival were secondary end points.

91 t was hemodialysis independence at 3 months; secondary end points: hemodialysis independence rates at

92 Group differences on secondary endpoints of disease progression measuring cog

93 The secondary endpoints were physiological parameters, durat

94 se in luciferase expression, coinciding with secondary energy failure, in lesioned mice compared to c

95 munity regulators; however, their effects on secondary exosome secretion by distal organs have not be

96 , TGF-beta pathways are heavily regulated by secondary factors, such as membrane-associated EGF-CFC f

97 es is also discussed, since it underlies all secondary genomic analyses such as RNA sequencing (RNA-S

98 mplicated in >80% of lower grade gliomas and secondary glioblastomas and primarily affect residue 132

99 ns to be fully elucidated how progression of secondary growth is properly controlled.

100 We tested the hypothesis that reduced root secondary growth of dicotyledonous species improves phos

101 by serving as a liaison between primary and secondary health services to ensure they are receiving h

102 esoderm accompanied by the expression of the secondary heart field marker, Islet1.

103 pathogenetic features in STEC-HUS, aHUS, and secondary HUS are simultaneous damage to endothelial cel

104 Secondary hyperparathyroidism commonly complicates CKD a

105 Most proposals were for secondary hypothesis-generating questions, with only 1 p

106 Secondary immunogenicity outcomes are antibody titres at

107 disease that represent the average number of secondary infections produced by a random infectious ind

108 Treatment of secondary injury after severe traumatic brain injury bas

109 imaging-confirmed NHS including primary and secondary intracerebral hemorrhage, hemorrhagic transfor

110 Our study therefore suggests that secondary introgression, rather than ILS, explains most

111 Gas cluster ion beam-secondary ion mass spectrometry (GCIB-SIMS) has shown th

112 table isotope probing coupled with nanoscale secondary ion mass spectrometry (nanoSIMS) and fluoresce

113 lopment of 3D imaging cluster Time-of-Flight secondary ion mass spectrometry (ToF-SIMS) as a label-fr

114 Time-of-flight secondary ion mass spectrometry (ToF-SIMS) has received

115 Secondary ischemic end points were also evaluated.

116 nnectivity at the lower (primary) or higher (secondary) level of the auditory network.

117 main absorption lines for Cu, Zn and Si and secondary lines for Mn and Mg were selected to carry out

118 However, neither T cell recruitment into secondary lymphoid organs nor initial T cell activation

119 ve Ag-specific B cells arrive in Ag-draining secondary lymphoid organs, they may join the ongoing GC

120 Despite their absence in secondary lymphoid tissues during homeostasis, gammadelt

121 he upregulation of immunomodulatory genes in secondary lymphoid tissues.

122 Secondary measures included those same individual measur

123 n their expression and activity, providing a secondary mechanism to extend the hypoxic signalling res

124 rely on a simple molecule, the intracellular secondary messenger c-di-GMP (Bis-(3'-5')-cyclic dimeric

125 ronmental factors associated with changes in secondary metabolism across natural environments.

126 thermore, the role of Xpp1 as a repressor of secondary metabolism is shown by gene expression analyse

127 (Xpp1) in the regulation of both primary and secondary metabolism of Trichoderma reesei Xpp1 was prev

128 yocyanin is a virulence factor produced as a secondary metabolite by the opportunistic human pathogen

129 Enterobactin is a secondary metabolite produced by Enterobacteriaceae for

130 X-ray co-crystal structure of the synthetic secondary metabolite with the eukaryotic 80S ribosome.

131 Filamentous fungi produce a diverse array of secondary metabolites (SMs) critical for defense, virule

132 Distinctive patterns in the accumulation of secondary metabolites according to the main diversificat

133 ole-containing, highly modified, macrocyclic secondary metabolites made from ribosomally synthesized

134 etide synthases and the determination of the secondary metabolites of xpp1 deletion and overexpressio

135 Phlorotannins are secondary metabolites produced by brown seaweed, which a

136 Bacteria produce a diverse array of secondary metabolites that have been invaluable in the c

137 9 associations influencing 13 primary and 19 secondary metabolites with large effects at high resolut

138 us Aspergillus nidulans synthesizes numerous secondary metabolites, including sterigmatocystin (ST).

139 analysis, and was able to identify 14 fungus secondary metabolites, namely aflatoxin B1, aflatoxin G1

140 advantage by secreting various nutrients and secondary metabolites.

141 smonate (MeJ) could improve the synthesis of secondary metabolites.

142 development and ability to produce numerous secondary metabolites.

143 ment of specific members of CYP450 family in secondary modifications for the biosynthesis of bioactiv

144 nd fast body bends, more ventral, higher-Rin secondary motoneurons (SMns) are recruited during weaker

145 sms involved in the dynamic deterioration of secondary MR during exercise, its functional and prognos

146 Although secondary MR is characteristically dynamic in nature and

147 An exercise-induced increase in secondary MR, however, is associated with impaired exerc

148 Because DFNA5-induced secondary necrosis and GSDMD-induced pyroptosis are depe

149 t that targets the plasma membrane to induce secondary necrosis/pyroptosis.

150 The secondary objective was the test performance, based on r

151 A secondary objective was to assess changes in left ventri

152 Secondary objective was to compare cost analyses using h

153 Secondary objectives are to determine if patient age, an

154 Secondary objectives include determining the incidence r

155 atients with early-stage BC receiving an AI; secondary objectives included evaluation of adverse even

156 Secondary objectives included patients' assessment of th

157 Secondary objectives included progression-free survival

158 ikely inhaling more fresh OC2 and OC3, since secondary OC4 and PC varies much less drastically in spa

159 Although secondary ocular blast injuries due to flying debris are

160 ing from single stranded regions to discrete secondary or tertiary structures.

161 eatures may come from the primary sequences, secondary or three dimensional structures of macromolecu

162 Secondary organic aerosol (SOA) formation during photo-o

163 temperature and concentration dependence of secondary organic aerosol (SOA) yields has been investig

164 between-group differences were seen for any secondary outcome at 4 weeks or the end of follow-up.

165 Secondary outcome measures include IOP, glaucoma medical

166 Secondary outcome measures included the time until onset

167 d no significant effect on RV dysfunction or secondary outcome parameters in repaired tetralogy of Fa

168 Secondary outcome was survival to hospital discharge wit

169 The secondary outcome was survival.

170 Our secondary outcome was the diagnosis of overt PH in patie

171 was the prespecified, multiplicity-adjusted secondary outcome.

172 y mortality with Medicare reimbursement as a secondary outcome.

173 he referral of black and white patients as a secondary outcome.

174 Secondary outcomes included a composite of mortality or

175 Secondary outcomes included adjusted time-weighted avera

176 Secondary outcomes included conversion to multiple scler

177 Secondary outcomes included death and death-censored all

178 Secondary outcomes included energy self-regulation and e

179 Secondary outcomes included ICU admission rate, in-hospi

180 Secondary outcomes included immunogenicity and antibody

181 Secondary outcomes included incidence of malaria, parasi

182 Secondary outcomes included inflammatory markers.

183 Secondary outcomes included major adverse cardiovascular

184 Secondary outcomes included major adverse cardiovascular

185 Secondary outcomes included other distress-related measu

186 Secondary outcomes included rate of reepithelialization,

187 Secondary outcomes included recurrence of endometrial ca

188 king channel culture showing 1 or more MDRO; secondary outcomes included the frequency of duodenoscop

189 rimary outcome of in-hospital mortality, and secondary outcomes including 30-day mortality, in-hospit

190 verse Simpson's alpha-diversity index), with secondary outcomes of beta and gamma Simpson's and Shann

191 Trial sequential analyses on primary and secondary outcomes suggested that required information s

192 Secondary outcomes were clinician-assessed remission of

193 Meta-estimates for primary and secondary outcomes were derived using a binomial-normal

194 Secondary outcomes were impaired functioning (measured b

195 Secondary outcomes were reconsultation, further antibiot

196 Secondary outcomes were splenic injury and aspiration pn

197 Secondary outcomes were the associations between antidep

198 Included among 10 prespecified secondary outcomes were the PHQ-9 score at 12-month foll

199 Primary and secondary outcomes were transplant hospitalization morta

200 sure cytokine production relevant to asthma (secondary outcomes).

201 ated with increased risk of any of the other secondary outcomes.

202 s with baseline vitamin D deficiency and for secondary outcomes.

203 nt-centered communication but did not affect secondary outcomes.

204 ath and incident chronic kidney disease were secondary outcomes.

205 dition, it was necessary to pool primary and secondary outcomes.INT that is provided by a dietitian c

206 The use of a secondary oven is often the solution to the problem.

207 nscripts localize initially to the precursor secondary parietal cells then predominantly to daughter

208 st phases and speciation in both primary and secondary phases.

209 ce accumulates high foliar concentrations of secondary phenolic metabolites, with important functions

210 roduction of PhCN to the reactions involving secondary phosphines with hydrosilanes allowed the heter

211 ist to improve the quality of cardiovascular secondary prevention care among patients with diabetes m

212 ls comparing anticoagulants with aspirin for secondary prevention in arterial thrombosis and aspirin

213 527 users of low-dose aspirin for primary or secondary prevention in the Swedish prescription registe

214 fectiveness of AIT and its potential role in secondary prevention of respiratory allergy progression.

215 ecent meta-analyses and randomized trials on secondary prevention of squamous cell carcinoma observed

216 aspirin with anticoagulants for primary and secondary prevention of venous thrombosis.

217 Attainment of 5 secondary prevention parameters-aspirin use, lipid contr

218 ich was added to standardised cardiovascular secondary prevention therapy.

219 AM/TSP, 74 relapsing-remitting MS [RRMS], 17 secondary progressive MS [SPMS], and 40 primary progress

220 rate of whole brain atrophy in patients with secondary progressive multiple sclerosis (SPMS).

221 tients should be preferentially targeted for secondary prophylaxis and/or regular medical follow-up.

222 tricular assist device patients who received secondary prophylaxis with octreotide after their index

223 Then, they serve as the secondary pump, and deep-UV SHs are generated within the

224 ls to pyidinium salts are documented: harder secondary radicals favor C-2 addition (2->10:1), while s

225 recovered from reservoirs using primary and secondary recovery mechanisms, and thus a major focus of

226 tance determinants, collectively termed the "secondary resistome".

227 e host institution and underwent primary and secondary reviews before analysis.

228 Here, we report that the architecture of the secondary root system in flooded rice plants is controll

229 In contrast, in secondary S. venezuelensis infection, our evidence indic

230 f formal education attained (primary school, secondary school, or tertiary education) and the allocat

231 nnual, cross-sectional survey of students in secondary schools in the contiguous United States.

232 ed infectious complications in patients with secondary sclerosing cholangitis.

233 e safety of ERC, especially in patients with secondary sclerosing cholangitis.

234 d 18% of anal biopsies following initial and secondary screening, respectively.

235 pment, gonad differentiation, development of secondary sex characteristics (SSC) and gametogenesis.

236 s BMP4 acts as a morphogen but this requires secondary signals and particular cell densities.

237 Conditional analyses distinguished six secondary signals at NOS1AP (n = 2), ATP1B1 (n = 2), SCN

238 um patterns between the 13 lead SNPs and six secondary signals with previously reported index SNPs in

239 k to its wild-type position by mutation at a secondary site with restoration of wild-type two-pronged

240 rminal mannose residue occupying an adjacent secondary site.

241 ntinuous growth, whereas the newly nucleated secondary small nuclei through a concentration change ha

242 Many of the same secondary structural features in both enzymes are pertur

243 hed with proline residues that regulate both secondary structure and aggregation propensity.

244 difficult to determine, and the link between secondary structure and RNA conformation is only beginni

245 by these fermentative aroma compounds on the secondary structure and stability of VVTL1, a Thaumatin-

246 eristic 2D IR features of amyloid beta-sheet secondary structure are created by as few as four or fiv

247 mino acid residues to participate in helical secondary structure at room temperature in the absence o

248 RNA in terms of both nucleotide sequence and secondary structure but differs from it in that its regu

249 chroism spectroscopy was used to confirm the secondary structure content and the stability through te

250 mation of a protein; not only its percentage secondary structure content, but also the juxtaposition

251 NCX1 palmitoylation is governed by a distal secondary structure element rather than by local primary

252 Analyses of secondary structure elements revealed substantial change

253 four or five strands and so identify amyloid secondary structure even if the aggregates themselves ar

254 ighly ordered beta-sheets typical of amyloid secondary structure even if the fibers themselves are to

255 Collectively, 5 induces strong secondary structure in Abeta and inhibits its functions

256 el method (RS3D) that can assimilate the RNA secondary structure information, small-angle X-ray scatt

257 However, although a large contributor, secondary structure is not the only factor that influenc

258 e-specific classification of two independent secondary structure motifs.

259 l polysaccharides induced similar changes in secondary structure of gluten proteins concerning format

260 d formation mechanism and the quaternary and secondary structure of soluble NFGAIL oligomers.

261 ) linked to increased cancer risk alters the secondary structure of the paRNA, with the risk allele f

262 These findings illustrate that the secondary structure of the RNA molecule-and its absence-

263 ality depends on segment length, the type of secondary structure of the segment and local quality of

264 protein residue-residue contact prediction, secondary structure prediction, and fold recognition.

265 of peptoid foldamers yields a new and unique secondary structure that we term an "eta-helix" due to i

266 onal diversity, ncRNAs mostly preserve their secondary structure throughout the dynamic ensemble.

267 oncert with prior knowledge of the canonical secondary structure, allow accurate inference of non-can

268 -40 conformations were analyzed by computing secondary structure, backbone fluctuations, tertiary int

269 cessary for transcription process stimulates secondary structure-formation thereby amplifying the pot

270 depicting the alignment of sequences on the secondary structure.

271 orm internal base pairs, leading to a folded secondary structure.

272 volution with implications for targeting and secondary structure.

273 eful guide: Peptide macrocycles lack regular secondary structures and hydrophobic cores, and can cont

274 DNA secondary structures and methylation are two well-known

275 on of the TurboFold algorithm for predicting secondary structures for multiple RNA homologs.

276 ies show that compound 1 also forms extended secondary structures in solution.

277 strate concurrent targeting of different DNA secondary structures offers an effective, precise, medic

278 science has motivated the development of new secondary structures that can serve as architectural ele

279 Secondary study end points were fractional flow reserve

280 this study, we aimed to explore the roles of secondary surgical cytoreduction and bevacizumab in this

281 based organic processes of evolution and the secondary system of cultural inheritance that is based o

282 The secondary, tertiary, and quaternary structures of squid

283 teria phenotypically tolerant to antibiotics secondary to a reduced metabolic state.

284 by fibers of the oculomotor nerve in DRS is secondary to absence of the abducens nerve.

285 has been implicated in cell death signaling secondary to axonal damage in retinal ganglion cells (RG

286 were those 16 or older with thrombocytopenia secondary to bone marrow failure, requiring prophylactic

287 randomized trials of BMAs in control of pain secondary to bone metastases.

288 with visual impairment due to macular edema secondary to branch retinal vein occlusion (BRVO).

289 By 12 weeks after TAC, mice developed CKD secondary to CHF associated with elevated renal GPCR-Gbe

290 However, outcomes remain poor secondary to corneal melting, scarring, and perforation.

291 Eighteen patients died, 14 secondary to disease.

292 f Ito currents in UNx EPI cardiomyocytes was secondary to downregulation of KChIP2 but not Kv4.2, Kv4

293 lammatory process involving the colonic wall secondary to fecal impaction with high morbidity and mor

294 on of the Shh pathway and breakdown of TJPs, secondary to increased MMP-9 activity which suggests tha

295 erforation following BAT is thought to occur secondary to mesenteric hematoma formation or mesenteric

296 notype, which are thus shown to be partially secondary to pathogen-induced inflammation.

297 ar AMD and 1 eye (3%) had neovascularization secondary to pseudoxanthoma elasticum, all showing simil

298 ne patient developed decreased visual acuity secondary to radiation retinopathy.

299 atural History of the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) study.

300 s results in faster resolution compared with secondary treatment.