ライフサイエンスコーパス: secondary bile acid

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1 potentially carcinogenic metabolites such as secondary bile acids.

2 nsistent with accumulation of TLCA and other secondary bile acids.

3 echanism underlying the oncogenic effects of secondary bile acids.

4 ficant shift in the abundance of primary and secondary bile acids.

5 lationship between polyp reduction and fecal secondary bile acids after feeding UDCA to these rats.

6 ected microbially modified molecules such as secondary bile acids and unexpected microbial molecules

7 rial 7 alpha-dehydroxylase and PI-PLC, fecal secondary bile acids, and colonic mucosal DAG kinase and

8 accompanied by decreased free and conjugated secondary bile acids as well as changes in gut microbiot

9 Secondary bile acids (BA) such as deoxycholic acid (DCA)

10 of dietary fat on colonic bacterial enzymes, secondary bile acids, colonic mucosal and tumor DAG kina

11 Fecal secondary bile acid concentrations were higher in Africa

12 novel role for specific bile acids, and the secondary bile acid DCA in particular, in the regulation

13 in the presence of physiologic levels of the secondary bile acid deoxycholate.

14 enzyme also activates chenodeoxycholate, the secondary bile acids deoxycholate and lithocholate, and

15 ation, enhances resistance to infection in a secondary bile acid dependent fashion.

16 In particular, the secondary bile acid derivative lithocholic acid (LCA) is

17 Levels of secondary bile acids, glucose, free fatty acids and dipe

18 aled that Goat(-/-) mice exhibited increased secondary bile acids >2.5-fold.

19 Secondary bile acids have long been postulated to be tum

20 We examined the effects of a natural secondary bile acid, hyodeoxycholic acid (HDCA), on lipi

21 Deoxycholic acid (DCA) is an endogenous secondary bile acid implicated in numerous pathological

22 A majority of primary and secondary bile acids in higher vertebrates have a 3alpha

23 carcinogenesis may include the production of secondary bile acids in the colon and the modulation of

24 Subsequently, mice were treated with these secondary bile acids in vivo to assess their ability to

25 t flora modify primary bile acids to produce secondary bile acids leading to a chemically diverse bil

26 Secondary bile acids like deoxycholic acid (DCA) are wel

27 hat VDR also functions as a receptor for the secondary bile acid lithocholic acid (LCA), which is hep

28 and lower fibre consumption, higher colonic secondary bile acids, lower colonic short-chain fatty ac

29 Because fecal secondary bile acids [particularly deoxycholic acid (DCA

30 Secondary bile acids, particularly deoxycholic acid (DCA

31 t-chain fatty acids pathway, and primary and secondary bile acids pathways.

32 dehydroxylase that is involved in generating secondary bile acids, phosphatidylinositol-specific phos

33 Microbial genes encoding for secondary bile acid production were more abundant in Afr

34 rial and colonic mucosal enzymes and colonic secondary bile acids relevant to colon tumor promotion.

35 or) protects the body from hepatotoxicity of secondary bile acids such as lithocholic acid (LCA) by i

36 fed the HFCO diet excreted higher levels of secondary bile acids, such as deoxycholic acid and litho

37 rmentation and butyrogenesis, and suppressed secondary bile acid synthesis in the African Americans.

38 r M-BAR) is a G protein-coupled receptor for secondary bile acids that is highly expressed in monocyt

39 erol is converted into dozens of primary and secondary bile acids through pathways subject to negativ

40 human livers were incubated with primary and secondary bile acids to determine their effects on LCFA

41 Primary bile acids were similar, whereas secondary bile acids were absent, in GF mdr2(-/-) mice.

42 Primary, but not secondary, bile acids were detected among the remaining

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