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1 Os, and during idiophase (after the onset of secondary metabolism).
2 le has yet to be described in the context of secondary metabolism.
3 te rapid and irreversible development of the secondary metabolism.
4 arbon metabolism, amino acid metabolism, and secondary metabolism.
5 oduce a wide range of chemical compounds via secondary metabolism.
6 how decreased virulence coupled with reduced secondary metabolism.
7 r biosynthetic pathways in plant specialized/secondary metabolism.
8 by natural variation in Arabidopsis thaliana secondary metabolism.
9  capacity with the precursors of primary and secondary metabolism.
10  remains one of the key unsolved problems of secondary metabolism.
11  important condensation enzymes in microbial secondary metabolism.
12 erating at the interface between primary and secondary metabolism.
13 sis and as an arginine in those dedicated to secondary metabolism.
14 portant insights into the evolution of plant secondary metabolism.
15 ease, presumably to enable higher flux, into secondary metabolism.
16  sulfur partitioning between the primary and secondary metabolism.
17        It has very few genes associated with secondary metabolism.
18 ngoing evolution of biosynthetic pathways in secondary metabolism.
19  pathway, reflecting the plasticity of plant secondary metabolism.
20 uptake, vesicle trafficking, and hormone and secondary metabolism.
21 ing, and elaboration of complex molecules in secondary metabolism.
22 substances (hairs, waxes) derived from plant secondary metabolism.
23 ly of NADPH-dependent reductases involved in secondary metabolism.
24 e most common transformations in primary and secondary metabolism.
25 ltransferases (OMTs) play important roles in secondary metabolism.
26  is a critical component of both primary and secondary metabolism.
27 glucosinolate (GSL) biosynthesis, as part of secondary metabolism.
28 ies associated with gene annotation in plant secondary metabolism.
29 sue differentiation, cell cycle control, and secondary metabolism.
30 enes and large suites of enzymes involved in secondary metabolism.
31 n regulating carbon flux between primary and secondary metabolism.
32 al functions, and evolution of plant terpene secondary metabolism.
33 I terpene synthase paralogs involved in rice secondary metabolism.
34 ease resistance genes, and genes involved in secondary metabolism.
35 nscription, translation, cell signaling, and secondary metabolism.
36  growth, differentiation, pathogenicity, and secondary metabolism.
37 le, variable, and transitory nature of plant secondary metabolism.
38 ymes required for cell wall modification and secondary metabolism.
39  hyphal growth to tissue differentiation and secondary metabolism.
40 s of SCPL acyltransferases involved in plant secondary metabolism.
41 talysts in transacylation reactions of plant secondary metabolism.
42 aminoacyl-tRNA-dependent enzymes involved in secondary metabolism.
43 ified another SCPL protein involved in plant secondary metabolism.
44 mination, root hair spacing, and anthocyanin secondary metabolism.
45  reactions used in biosynthetic reactions of secondary metabolism.
46 ction relationships in a key enzyme of plant secondary metabolism.
47 re represents a junction between primary and secondary metabolism.
48  to the needs for both protein synthesis and secondary metabolism.
49  with a single plasmid carrying two genes of secondary metabolism.
50 lkaloid biosynthesis as it links primary and secondary metabolism.
51 xample of convergent functional evolution in secondary metabolism.
52  great intraspecific variability in mulberry secondary metabolism.
53  brassinosteroids and related to primary and secondary metabolism.
54 tics including pathogenesis, development and secondary metabolism.
55  unravel its role in the regulation of plant secondary metabolism.
56 e influences range from biofilm formation to secondary metabolism.
57 and has become a useful model for studies of secondary metabolism.
58 tress responses, hyphal growth, and possibly secondary metabolism.
59 thway into the interface between primary and secondary metabolism.
60 e development, stress response pathways, and secondary metabolism.
61  genes and three gene deletions that enhance secondary metabolism.
62 ed the potential for feed-back regulation of secondary metabolism.
63 -CoA/propionyl-CoA intracellular balance and secondary metabolism.
64 ways to supply more aromatic amino acids for secondary metabolism.
65  and to other studies of natural variance of secondary metabolism.
66 evelopment, as well as amino acid, iron, and secondary metabolism.
67 arbon skeleton rearrangements in primary and secondary metabolism.
68 l for functional analysis of tandem genes in secondary metabolism.
69 odelling, autophagy, signal transduction and secondary metabolism.
70 ricarp transcriptome in stress responses and secondary metabolism.
71  first studies of a UGDH homolog involved in secondary metabolism.
72  are a well-established feature of microbial secondary metabolism.
73 ism and the subsequent changes in downstream secondary metabolism.
74 S) known to influence biological control and secondary metabolism.
75 defense, defense signaling, oxidative burst, secondary metabolism, abiotic stress, cell maintenance,
76 ronmental factors associated with changes in secondary metabolism across natural environments.
77 rtant in increasing the understanding of how secondary metabolism affects plant development.
78 pt for a higher number of AraCyc pathways in secondary metabolism and a 1.5-fold increase in carbohyd
79 regulator), serves as a global gatekeeper of secondary metabolism and a repressor of numerous BGCs.
80 at PPO plays a novel and fundamental role in secondary metabolism and acts as an indirect regulator o
81 er in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative
82 mary metabolism genes, the genes involved in secondary metabolism and certain nutrient utilization pa
83 xpression of genes involved in pathogenesis, secondary metabolism and conidiation.
84  attacking each other with toxic products of secondary metabolism and defending themselves via an ars
85 s analyzed to provide a holistic overview of secondary metabolism and defense processes in the model
86       Deletion of veA, a global regulator of secondary metabolism and development, nearly eliminated
87 ' regulator, suppressing central metabolism, secondary metabolism and developmental pathways until su
88 ide enzymes for many pathways of primary and secondary metabolism and for the conjugation of hormones
89  opportunity to advance our understanding of secondary metabolism and fungal defense mechanisms.
90 y of proteins that have specialized roles in secondary metabolism and in normal cell development.
91 ty associated with several key regulators of secondary metabolism and morphological development in S.
92 A-factor regulatory cascade, controlling the secondary metabolism and morphological differentiation o
93 endent synthesis of proteins associated with secondary metabolism and oxidative and thermal stress re
94 l identity, sexual and asexual reproduction, secondary metabolism and pathogenesis in F. graminearum.
95  cork oak phellem, such as those involved in secondary metabolism and phellogen activity.
96 Gly and Ser reflected growing commitments to secondary metabolism and photorespiration, respectively.
97 proteins involved in other processes such as secondary metabolism and protein biosynthesis were gener
98 link between the transition to flowering and secondary metabolism and provide a potential target for
99 transcription factor TT8 is an integrator of secondary metabolism and stress response.
100 l reactions in D. rerio for both primary and secondary metabolism and the implementation of methods f
101 thogenicity, genes for secreted proteins and secondary metabolism and the pathogen-host interaction d
102 associated with a transition from primary to secondary metabolism and the production of antibiotics.
103 be utilized to characterize genes related to secondary metabolism and their regulation, and in breedi
104                Gamma-butyrolactones regulate secondary metabolism and, sometimes, sporulation in acti
105                         In summary, quinate (secondary metabolism) and shikimate (primary metabolism)
106 le processes, such as ethylene biosynthesis, secondary metabolism, and glutathione turnover.
107  red light photobiology, genes implicated in secondary metabolism, and important differences in Ca2+
108 nesis, cell division, virulence, primary and secondary metabolism, and intrinsic antibiotic resistanc
109 genus' astounding dexterity and diversity in secondary metabolism, and on the genetic underpinnings o
110 nes involved in plant cell wall degradation, secondary metabolism, and secreted peptidases and effect
111  including energy conversion, ion transport, secondary metabolism, and signal transduction.
112 ted gene clusters are the hallmark of fungal secondary metabolism, and there is a growing body of evi
113 alance among growth, primary production, and secondary metabolism, and thus aid in the development of
114  10,000 different diterpenes of specialized (secondary) metabolism, and fewer diterpenes of general (
115         Iron metabolism, monooxygenases, and secondary metabolism appeared to participate in isolate
116      Most elucidated hydroxylations in plant secondary metabolism are catalyzed by oxoglutarate- or c
117 rovide compounding evidence that primary and secondary metabolism are differentially programmed in bo
118 e, most of the enzymatic components of plant secondary metabolism are encoded by small families of ge
119 , products of the phenylpropanoid pathway of secondary metabolism are involved in interactions with b
120 ical mechanisms underlying morphogenesis and secondary metabolism are rarely revealed, partially beca
121 ation, compound leaf development and profuse secondary metabolism, are absent in the typical model pl
122  assess the interconnectivity of primary and secondary metabolism as well as to compare and contrast
123 revealed a novel cross talk in JAZ-regulated secondary metabolism, as irJAZh plants had significantly
124 s at high concentrations, act as inducers of secondary metabolism at low concentrations.
125  the feasibility of Ag NPs to inhibit fungal secondary metabolism at nonlethal concentrations, hence
126 eactions in Arabidopsis for both primary and secondary metabolism, automatic gap-filling, and the imp
127 rimethoprim, served as a global activator of secondary metabolism by inducing at least five biosynthe
128 ana attenuata, an ecological model with rich secondary metabolism, by combining tissue-wide nontarget
129 f the debate about the role and evolution of secondary metabolism can be accommodated within the view
130         We conclude that enzymes involved in secondary metabolism can be functionally exchangeable be
131 dated within the view that the possession of secondary metabolism can enhance fitness, but that many
132  small-molecule chemistry in microbes (i.e., secondary metabolism) can modulate the microbe-host resp
133  missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and t
134  extensive gene sets involved in central and secondary metabolism, cell cycle and transcription, but
135 remarkable gene sets involved in central and secondary metabolism, cell cycle, transcription, signall
136 ated to ribosome biogenesis and translation, secondary metabolism, cell wall modification and growth.
137                                    Microbial secondary metabolism constitutes a rich source of antibi
138 ll, lipid metabolism, stress, transport, and secondary metabolism culminated in the differentiation z
139 in numerous processes, including primary and secondary metabolism, development, and responses to abio
140  ethylene biosynthesis, fruit softening, and secondary metabolism during fruit development and ripeni
141 A, ssgB, ftsZ, whiB, whiG, smeA-ssfA) and/or secondary metabolism (e.g. nsdA, cvn9, bldA, bldC, leuA)
142  clusters encoding enzymes characteristic of secondary metabolism, eight are represented on the prote
143 nes encoding carbohydrate active enzymes and secondary metabolism enzymes.
144 te the mechanism by which light induces root secondary metabolism, extracts of mutants defective in l
145 ked to polyamine catabolism, osmoprotection, secondary metabolism (fragrance), and carnitine biosynth
146 t understanding of the genetic regulation of secondary metabolism from clustering of biosynthetic gen
147 hetic process reflects derivation of related secondary metabolism from the GA primary biosynthetic pa
148                                              Secondary metabolism gene clusters are probably responsi
149 two genomes show distinct variations in many secondary metabolism gene clusters.
150 gger compensatory transcriptional changes in secondary metabolism genes analogous to those observed i
151 isproportionately enriched in regulation and secondary metabolism genes and depleted in protein trans
152 natorial biosynthesis involves interchanging secondary metabolism genes between antibiotic-producing
153   However, under laboratory conditions, most secondary metabolism genes remain silent.
154  terpenoid synthases involved in primary and secondary metabolism have been cloned and characterized.
155 t catalyze transacylation reactions in plant secondary metabolism have been identified from wild toma
156                Several paradigms that govern secondary metabolism have emerged, including that (1) ge
157 ochemical and genetic studies on primary and secondary metabolism have laid a solid foundation for th
158 cts of culture geometry and growth matrix on secondary metabolism, highlighting the potential use of
159                                              Secondary metabolism improves and modulates the phenotyp
160 ependent regulator governing development and secondary metabolism in Aspergillus nidulans.
161 and Lae1, whereas Sge1, a major regulator of secondary metabolism in F. fujikuroi, affects gibepyrone
162 fferentiation, multiple stress responses and secondary metabolism in F. graminearum.
163           Genes involved in intermediary and secondary metabolism in fungi are frequently physically
164  possible functions of these related OMTs in secondary metabolism in M. truncatula, seven of the OMTs
165      Polyketides, the ubiquitous products of secondary metabolism in microorganisms, are made by a pr
166 at screens for expressed enzymes involved in secondary metabolism in microorganisms.
167        Here we describe a novel repressor of secondary metabolism in P. aureofaciens strain 30-84, Rp
168              Sulfur is vital for primary and secondary metabolism in plant roots.
169 -level versus pathway-specific regulation of secondary metabolism in Streptomyces species is warrante
170  genomics is providing a mechanism to assess secondary metabolism in the context of evolution and evi
171 ith the delayed morphological development or secondary metabolism in the DeltaclpP background after r
172 e resulting complexes govern development and secondary metabolism in the filamentous fungus Aspergill
173 ection between oxidative stress response and secondary metabolism in the filamentous fungus Aspergill
174 estigate the genomic regions associated with secondary metabolism in tomato fruit pericarp.
175       As part of our studies of specialized (secondary) metabolism in tomato (Solanum lycopersicum) t
176 those involved in cell wall biosynthesis and secondary metabolism, including cyanogenic glucoside for
177                      Novel genes involved in secondary metabolism, including genes implicated in ophi
178 ulfur trafficking in primary metabolism, the secondary metabolism involving sulfur has long been negl
179 ay in streamlined bacteria demonstrates that secondary metabolism is an essential component of the sy
180 th sexual and asexual development as well as secondary metabolism is consistent with the dual regulat
181                       Fungal development and secondary metabolism is intimately associated via activi
182 itical overview of engineering approaches in secondary metabolism is presented, both in heterologous
183 thermore, the role of Xpp1 as a repressor of secondary metabolism is shown by gene expression analyse
184 lines of experimental evidence indicate that secondary metabolism is triggered by oxidative stress; h
185  how gluconisolate biosynthesis, regarded as secondary metabolism, is intricately linked with hormone
186 es and at least two key global regulators of secondary metabolism, laeA and veA, with a concomitant r
187 ished by deletion of the global regulator of secondary metabolism, laeA, and to a lesser extent by de
188 under the control of the master regulator of secondary metabolism, LaeA, contains, in its entirety, t
189 -chain dehydrogenases/reductases involved in secondary metabolism (lignan biosynthesis), stress respo
190                       Despite having limited secondary metabolism, many oomycetes make chemicals for
191 ar evolutionary approach focused on genes of secondary metabolism may have broad implications for the
192 rolling important cellular processes such as secondary metabolism, motility, biofilm formation and th
193 nformation on data quality, expansion of the secondary metabolism node of the pathway ontology to acc
194 and showcases a strategy of manipulating the secondary metabolism of an organism to improve traits re
195                JHDK is an enzyme crucial for secondary metabolism of JH and possesses high specificit
196 ethyltransferase superfamily involved in the secondary metabolism of many species across all kingdoms
197 iously, these acids were thought to arise by secondary metabolism of the major nicotine metabolite co
198 (Xpp1) in the regulation of both primary and secondary metabolism of Trichoderma reesei Xpp1 was prev
199 ring the final stages (i.e., sporulation and secondary metabolism) of cellular differentiation.
200 sglutaminases, whereas mel(2) is involved in secondary metabolism or biosynthesis of fatty acids.
201 idating this important reaction of the plant secondary metabolism our study provides a foundation for
202 include genes involved in carbon metabolism, secondary metabolism, P scavenging and remobilization, p
203 kinin on genes encoding proteins involved in secondary metabolism, particularly those acting in flavo
204 son is the discovery of a vast repertoire of secondary metabolism pathways and of numerous small cyst
205 ans reveals that the products of many of the secondary metabolism pathways in these fungi have not be
206                         Analysis of putative secondary metabolism pathways might facilitate the disco
207 the other (OsCPS2ent) is involved in related secondary metabolism producing defensive phytochemicals.
208 n of carrier-protein activity in primary and secondary metabolism, providing insight into pathways th
209 tly repressing genes involved in central and secondary metabolism, redox balancing, and the consumpti
210 or carbon storage regulator and regulator of secondary metabolism, respectively; hereafter called Csr
211 lla microbiome and its impact on primary and secondary metabolism, revealing a remarkable versatility
212                       RsmA (for regulator of secondary metabolism), RsmC, and rsmB RNA, the component
213                                   Aside from secondary metabolism, ScmR also represses biofilm format
214 esults indicate that FgSSN3 is important for secondary metabolism, sexual reproduction, and plant inf
215  metabolism (FAS) and the other required for secondary metabolism (sFAS).
216 own to function as acyltransferases in plant secondary metabolism: sinapoylglucose:malate sinapoyltra
217  suggested that CaMYB31 could be involved in secondary metabolism, stress and plant hormone responses
218 cts of fungal biology, including primary and secondary metabolism, stress response, biomass degradati
219 g nutrient availability: growth, adaptation, secondary metabolism, survival, persistence, cell divisi
220 ed into three distinct lineages in bacterial secondary metabolism systems and these were precursors o
221 the draft genome are putatively dedicated to secondary metabolism, this is far too few to encode a la
222  exist to exploit these unique properties of secondary metabolism to enhance secondary product divers
223 ere primary metabolites of tamoxifen undergo secondary metabolism to form DNA adducts, which are dete
224 found in proteins are shunted into microbial secondary metabolism to form peptide antibiotics by spec
225  some of the sulfate is partitioned into the secondary metabolism to synthesize a variety of sulfated
226                       Plants deploy distinct secondary metabolisms to cope with environment pressure
227 d form, deoxynivalenol-3-O-glucose (D3G), by secondary metabolism UDP-glucosyltransferases (UGTs).
228 th important substrates for both primary and secondary metabolism via the oxidation of glucose-6-phos
229 gest that ScmR is a pleiotropic regulator of secondary metabolism, virulence, biofilm formation, and
230  sulfur partitioning between the primary and secondary metabolism, we analysed plants in which activi
231 pergillus, a fungal genus known for its rich secondary metabolism, we characterize the effects of cul
232 rder to advance the exploration of microbial secondary metabolism, we developed the largest publicall
233 y, 16 cytochrome P450 transcripts related to secondary metabolism were also identified.
234 Heritability analyses revealed that mQTLs of secondary metabolism were less affected by environment t
235 ganic remediation, antibiotic resistance and secondary metabolism were shown to significantly vary be
236 ly sets of proteins related to transport and secondary metabolism were upregulated, while in the pres
237  (c-di-GMP) signalling, iron homeostasis and secondary metabolism, were influenced by one or both reg
238 lex interactions with downstream branches of secondary metabolism, which is currently poorly understo
239 ysaccharide degradation, nutrient uptake and secondary metabolism, which may result from adaptations
240 ive to such inhibition than those devoted to secondary metabolism, which presumably limits flux towar
241 of genes including many that are involved in secondary metabolism, while downregulating a smaller num
242                          It is proposed that secondary metabolism will have evolved such that traits
243 n enhance fitness, but that many products of secondary metabolism will not enhance the fitness of the
244 specific localization of pathways underlying secondary metabolism within a plant.
245 ross talk that can occur between primary and secondary metabolism within transgenic plants.

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