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4 henomena are due, in part, to the deployment/secretion of a "decoy flare," for example, anomalous can
5 rbates ER stress-dependent reductions in the secretion of a destabilized, aggregation-prone protein a
6 y undescribed invasive mechanism whereby the secretion of a glutathione-dependent oxidoreductase driv
7 concordantly decrease the constitutive CCL17 secretion of a human Hodgkin lymphoma cell line and prev
9 type because EHF depletion alters epithelial secretion of a neutrophil chemokine and slows wound clos
10 activation by cholesterol sulfate causes the secretion of a range of proinflammatory mediators, and s
11 oach by enhancing production of tyrosine and secretion of a recombinant protein in Saccharomyces cere
12 nutrient starvation-specific unconventional secretion of Acb1 in Saccharomyces cerevisiae requires E
14 on antigen-presenting cells, EPO induced the secretion of active TGFbeta by antigen-presenting cells,
15 onclusion, these data suggest that increased secretion of activin A, particularly from microglia, in
17 K5 resulted in AD-like skin architecture and secretion of AD-related cytokines from keratinocytes in
19 lar replicative cycle of T. gondii including secretion of adhesins, motility, invasion, and egress.
20 mechanosensing ability of mussels, deterring secretion of adhesive threads, and decreasing the molecu
21 ancreatic islets, yielding similar levels of secretion of albumin or of glucose-inducible levels of i
24 nate (JA) signaling pathway, which initiates secretion of an acidic hydrolase mixture to decompose th
25 sition that blue light filtering affects the secretion of angiogenic factors by retinal pigmented epi
26 cretion of inflammatory cytokines and higher secretion of anti-inflammatory cytokines from activated
27 Serratia AS1 was genetically engineered for secretion of anti-Plasmodium effector proteins, and the
28 mpounds that prime microbial pattern-induced secretion of antimicrobial furanocoumarins (phytoalexins
34 BIGs together with ECH and ARF1 mediate the secretion of AUX1 influx carrier to the plasma membrane
35 dings imply a role for the RxLR motif in the secretion of AVR3a by the pathogen, rather than a direct
37 le of C5L2 in pulp nerve regeneration in the secretion of BDNF by pulp fibroblasts under sites of car
38 led that vacuoles were exocytic and mediated secretion of beta-hexosaminidase and cytokines accompani
41 subunit inhibits misfolding and thus allows secretion of biologically active heterodimeric IL-12.
42 th in vivo and in vitro, as characterized by secretion of both proinflammatory and anti-inflammatory
43 th toward carious injuries by modulating the secretion of brain-derived neurotrophic factor (BDNF) by
44 urb protein folding, assembly or polarity of secretion of C1QTNF5 and, importantly, all appear to des
46 g by MSC was found to be mediated in part by secretion of cathelicidin and was significantly increase
49 action between CD8+ T cells and BECs through secretion of CCL5 might promote the phosphorylation of S
50 ensity of glioma to colonize the SVZ through secretion of chemoattractant signals toward which glioma
51 luence prostate cancer behaviour through the secretion of chemokines and growth factors, acting in a
52 DCs up-regulate costimulatory molecules and secretion of chemokines, but not of cytokines typical of
54 The altered bile salt pool stimulated robust secretion of cholesterol into the intestinal lumen via t
57 e (PGANT4) in Drosophila results in aberrant secretion of components of the peritrophic/mucous membra
58 odendrocyte maturation through the regulated secretion of connective tissue growth factor (CTGF).
59 als are a major endocrine site of production/secretion of constitutive pepcan-12, as shown by its mar
60 ansmembrane domain of CpaB results in robust secretion of CpaA and CpaB, indicating that the transmem
63 Expansion of R gnavus in mice stimulated secretion of cytokines (interleukin [IL] 25, IL33, and t
64 pathway that can be targeted to inhibit the secretion of cytokines by modulating either CXCR4 or CXC
65 he induction of T-cell proliferation and the secretion of cytokines in Peripheral blood mononuclear c
68 that GSDMD pores represent conduits for the secretion of cytosolic cytokines under conditions of cel
69 on, and acinar cell homeostasis required for secretion of digestive enzymes relies on SNARE-mediated
70 link to seagrass-derived radial O2 loss and secretion of dissolved organic carbon from the below-gro
71 e chemokine receptor expression profiles and secretion of diverse effector molecules, suggesting func
74 eraction interface significantly reduced the secretion of effector proteins and HeLa cell cytotoxicit
76 om the plasma, and in some instances genital secretions, of eight HIV-1 donor and recipient pairs.
78 n between empty capsids and the envelope for secretion of empty virions.IMPORTANCE The phosphorylatio
79 f carbon is hypothesized to be driven by the secretion of enzymes by microbial organisms (5-7) , whic
80 lectrophysiological principles that regulate secretion of essential lubricants (hyaluronan and lubric
84 tudies, we establish that SRC stimulates the secretion of exosomes having promigratory activity on en
86 al loading resulted in 2-4 folds increase in secretion of extracellular matrix proteins and the reorg
87 riptomic signature suggesting expression and secretion of extracellular proteins, while mature RRCs e
88 These findings suggest that targeting the secretion of extracellular, autocrine/paracrine mediator
90 elated pathologies, presumably through their secretion of factors contributing to the senescence-asso
92 that locally induces muscle atrophy, but via secretion of FGF21 acts distally to modulate whole-body
93 sms that involve activation of ER stress and secretion of fibroblast growth factor 21 (FGF21) from sk
94 pyruvate fully rescues the impaired insulin secretion of fission-deficient beta-cells, demonstrating
98 zed that palmitate simultaneously stimulates secretion of glucagon and insulin at fasting glucose con
99 tate levels to simultaneously increase basal secretion of glucagon and insulin positions elevated lev
102 n mucosal tissue, inflammation increased the secretion of granulocyte macrophage-colony stimulating f
104 Morbidly obese patients exhibit impaired secretion of gut hormones that may contribute to the dev
109 or weight loss as well as differences in the secretion of hormones that potentially modulate inflamma
110 Cells were stimulated with agonists, and secretion of Hsp90, urokinase, and TPA was measured in t
113 ressed the proliferation of Th cells and the secretion of IFN-gamma in a cell contact-independent man
114 xpression of the receptor that regulates the secretion of IgA into the intestinal lumen, the polymeri
116 phase of TLR signaling and the TLR-dependent secretion of IL-10 (controlled by IRAKs 1 and 2) was onl
120 n armored CAR T cell capable of constitutive secretion of IL-12, and delineate the mechanisms via whi
122 ome activation and suppressed pyroptosis and secretion of IL-1alpha and IL-1beta induced by intracell
123 rm cytotrophoblast cells, with a predominant secretion of IL-1beta and IL-6, a result confirmed in hu
127 pansion by elastic stresses led to increased secretion of IL-1beta, which in turn drove strong up-reg
132 of Vgamma9/Vdelta2 T cells promoted mucosal secretion of IL-22 and ICOSL/TNF-alpha-dependent release
136 pressive ligand PD-L1, a higher constitutive secretion of IL-6 and increased basal alphaSMA levels.
138 of neutrophils (mainly) and eosinophils and secretion of IL-6, TNF-alpha, and IL-17 in contrast to t
140 ficantly lower secretion of IL-10 and higher secretion of IL-9 by casein-stimulated T cells were foun
141 k out pig conceptus IL1B2 expression and the secretion of IL1B2 during the time of conceptus elongati
143 immune system to maintain homeostasis is the secretion of immunoglobulins (Igs) across epithelial bar
144 f immunotherapeutics in diverse ways such as secretion of immunosuppressive cytokines and expression
145 y LVD was mediated by TLR4, as we found less secretion of inflammatory cytokines and higher secretion
146 rd an inflammatory phenotype, with increased secretion of inflammatory cytokines as well as chemokine
147 how Rapa MPs modulate DC function, enhancing secretion of inflammatory cytokines at very low doses, a
148 y HOCl treatment was demonstrated by reduced secretion of inflammatory cytokines in affected skin tis
149 ereas knockdown of Irf5 blunted CB1R-induced secretion of inflammatory cytokines without affecting CC
152 tigens, via bound IgE antibody, and triggers secretion of inflammatory mediators that contribute to a
155 D21, triggered endosomal TLR7 and led to the secretion of interferon (IFN) alpha via an IRF5-dependen
156 DGF-DD engagement of NKp44 triggered NK cell secretion of interferon gamma (IFN)-gamma and tumor necr
158 pyroptotic cell death and the maturation and secretion of interleukin (IL)-1beta and IL-18, which tri
162 complex called the inflammasome, leading to secretion of interleukin-1 (IL-1) family cytokines, pyro
163 containing active catalase; and 3) selective secretion of interleukin-6, interleukin-10, and vascular
165 ed epidermal structure, ascribed to aberrant secretion of lamellar bodies, which are essential for ep
169 mmune synapse of B-cells relies on the local secretion of lysosomes, which are recruited to the Ag co
170 K4A (CDKN2A) and p21CIP1 (CDKN1A), increased secretion of many bio-active factors (the senescence-ass
171 These findings reveal a new route for the secretion of MASP proteins in T. cruzi, which uses EVs a
175 pt circadian patterns and decrease nocturnal secretion of melatonin, which may disturb estrogen regul
178 that late endosomal/lysosomal targeting and secretion of mHtt could be inhibited efficiently by the
181 nd that FFAs increase hepatic expression and secretion of MIR122, which regulates energy storage vs e
182 division through E-cadherin, which prevents secretion of mitogenic epidermal growth factors (EGFs) b
184 ion, via use of an eye drop, of AAV-mediated secretion of MMP-3 into AH could have therapeutic potent
185 innate immune system by participating in the secretion of MMP-7 which in turn is important for the sh
189 nd by E-selectin and, on ligation, initiates secretion of MRP8/14 that binds TLR4 to elicit the exten
191 ductal cells, Yap drives the expression and secretion of multiple cytokines/chemokines, which in tur
192 he effects of SMF on the gene expression and secretion of neurotrophic factors- BDNF and NT3 was quan
193 is factor-stimulated enhanced expression and secretion of NF-kappaB-targeted proinflammatory mediator
199 late oral pathogens from expressed prostatic secretions of patients with periodontal disease and CPr
201 ood platelets contain polyphosphate, and the secretion of platelet-derived polyphosphate has been ass
202 tase produced by Synechococcus and a dynamic secretion of potential hydrolytic enzyme candidates used
203 n 3) and GLUT1 (glucose transporter 1); (ii) secretion of pre-formed IL-8, and Charcot Leyden crystal
204 f pathogenic lymphocyte infiltration and the secretion of pro-inflammatory cytokines are involved in
207 mportantly, Ankrd26 down-regulation enhanced secretion of pro-inflammatory mediators by 3T3-L1 adipoc
209 lls, this was associated with an accelerated secretion of proinflammatory and profibrotic cytokines (
210 Both miR-25-3p and miR-92a-3p stimulated secretion of proinflammatory cytokine IL6 from tumor-ass
211 ur results indicate that FP7 antagonized the secretion of proinflammatory cytokines (IL-6, IL-8, and
212 terized by a stable proliferation arrest and secretion of proinflammatory cytokines and chemokines, t
213 versible cell-cycle arrest combined with the secretion of proinflammatory cytokines and mitochondrial
216 the inflammasome promotes caspase-1-mediated secretion of proinflammatory cytokines interleukin (IL)-
217 inase (IRAK)-1/IRAK-4-mediated signaling and secretion of proinflammatory cytokines such as IL-12, IL
218 the activation of the NF-kappaB pathway and secretion of proinflammatory cytokines TNF-alpha and IL-
223 R4-TLR6 assembly was associated with reduced secretion of proinflammatory mediators from microglia ce
224 ive pathway prevents the correct folding and secretion of proteins that are known to form non-native
225 xert their beneficial effects mainly through secretion (of regenerative factors) and membrane-based c
226 enic B. cereus isolates harbor genes for the secretion of S-layer proteins, for S-layer assembly, and
227 ion environment increased the expression and secretion of S100A12 by nearly 70%, which in turn activa
228 sts residing at the bone surface through the secretion of Sclerostin (SOST), an inhibitor of WNT sign
229 he deletion of Xpp1 resulted in the enhanced secretion of secondary metabolites in terms of diversity
230 c IgG, but not IgA, was detected in cervical secretions of serum antibody-positive animals, predomina
231 lar endothelial cells and causes endothelial secretion of several metastasis-promoting cytokines.
232 wherein BIM-23A760 inhibited the expression/secretion of several pituitary hormones (specially GH/PR
233 influence neuronal function not only through secretion of soluble factors (eg, cytokines and chemokin
234 sistant S.aureus (MRSA) are mediated via the secretion of soluble factors by viable cells in hCVAM an
235 Moreover, prostratin and bryostatin-1 induce secretion of some proinflammatory cytokines and an incre
239 nt keratinocytes show significantly impaired secretion of specific chemokines including CXCL1, CXCL8,
240 embers of the MpPR-1 family bind and promote secretion of sterols, whereas others bind and promote se
241 ntly, we were able to demonstrate that polar secretion of substrates is critically required for Legio
242 hat the cortical actin acts as a barrier for secretion of such large granules at the cell-cell contac
243 raves' disease, but not control sera, led to secretion of TG with an increased intrinsic ability to f
244 We observed a significant increase in the secretion of TGF-beta1 ligand along with enhanced protei
247 ruption of the actin network interferes with secretion of the biomineralised elements in both C. braa
249 r-1 (PAI-1) and stimulate the expression and secretion of the chemokine, CCL5, from ECs, which then a
250 isolated corrected single cell clone showed secretion of the corrected type VII collagen at similar
252 e kinase that regulates Th1 differentiation, secretion of the inflammatory cytokine gamma interferon
253 tion of activated B cells, inhibition of the secretion of the inflammatory factors such as IgG1, IgG2
254 ted with reduced macrophage infiltration and secretion of the macrophage attractant and growth factor
256 minent example of bacterial cooperation, the secretion of the peptide siderophore pyoverdine by Pseud
258 mutants promote longevity through increased secretion of the polysaccharide colanic acid (CA), which
259 hanistically, we found that Peg3 induced the secretion of the powerful angiostatic glycoprotein Throm
260 REB) activation and subsequent synthesis and secretion of the pro-repair WNT1-inducible signaling pro
262 inflammasome results in caspase-1-dependent secretion of the proinflammatory cytokines IL-1beta and
263 Within the pancreatic islet, IL-6 stimulates secretion of the prosurvival incretin hormone glucagon-l
264 A2 activity in these splenic macrophages and secretion of the resistance-inducing lipid mediator, lys
265 osa as a model system, the authors show that secretion of the siderophore pyoverdine only incurs a fi
267 of the microtubule network does not prevent secretion of the silica scales in P. neolepis but result
268 t strongly associated variant with decreased secretion of the soluble WNT-antagonist SFRP4, in surgic
269 in cancer is activity-dependent cleavage and secretion of the synaptic adhesion molecule neuroligin-3
270 ed rapid cell activation, proliferation, and secretion of the type 2 cytokines IL-5, IL-9 and IL-13 t
271 Rab35 mutant both inhibited histamine-evoked secretion of the WPB cargos von Willebrand factor and P-
278 tes did not seem to have a major role in the secretion of tissue inhibitors of metalloproteinases (TI
280 ), a DNA-binding protein capable of inducing secretion of TNF-alpha by a monocyte/macrophage cell lin
281 tutive defense against pathogens through the secretion of toxic cyclic diterpenes, such as the antimi
282 ocytes induce local fibroblast activation by secretion of transforming growth factor beta, and a pren
283 scue the impaired glucose-stimulated insulin secretion of transgenic mice, pointing to a potential me
286 s of new protein, is not caused by decreased secretion of TSP-4, and is mediated by activation of SMA
287 us, we hypothesized that autophagy-dependent secretion of tumor-promoting factors by HNSCC-associated
288 lergen clearance exacerbated Stat6-dependent secretion of type 2 cytokines, airway eosinophilia, and
289 tein in collagen biosynthesis, which retards secretion of type I collagen and causes excessive posttr
290 oid dendritic cells (pDC) are specialized in secretion of type I interferon in response to pathogens.
291 suggest that SRC-2 coordinates cardiomyocyte secretion of VEGF downstream of the two major angiogenic
292 y, leading to the notion that HCV coopts the secretion of very-low-density lipoprotein (VLDL) for its
293 to examine the intracellular generation and secretion of vitamin D metabolites along with the regula
294 to identify factors affecting synthesis and secretion of VLDL-TAG using the growth hormone-deficient
296 ristic of type 2B VWD, upon DDAVP-stimulated secretion of VWF leading to transient thrombocytopenia a
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