ライフサイエンスコーパス: secretion pathway

1 ry autophagy, an autophagy-based alternative secretion pathway.

2 fector proteins to plant cells via a type IV secretion pathway.

3 ly, and we suggest that they follow the same secretion pathway.

4 colitica exports Yop proteins via a type III secretion pathway.

5 problems is the type V (or autotransporter) secretion pathway.

6 pears to rely mostly on a distal step in the secretion pathway.

7 rotein to plant cells via the hrp (type III) secretion pathway.

8 mpartment of eukaryotic cells via a type III secretion pathway.

9 as a conduit for proteins that transit this secretion pathway.

10 oteins are normally exported via the type II secretion pathway.

11 g a possible role for these proteases in the secretion pathway.

12 s targeted to the cilia by an unconventional secretion pathway.

13 the cytoplasm of macrophages via a type III secretion pathway.

14 oteins that function in the type III protein secretion pathway.

15 require LepB and TraQ but not the SecA-SecY secretion pathway.

16 compete with each other for entrance to the secretion pathway.

17 ia the autotransporter (or type V) bacterial secretion pathway.

18 a C(1) compound known to block the type III secretion pathway.

19 ec-dependent mechanism and not by a type III secretion pathway.

20 am-negative bacteria via the autotransporter secretion pathway.

21 Hemolysin A belongs to the two-partner secretion pathway.

22 newly identified NO-cGMP-dependent platelet secretion pathway.

23 ke PNPase, regulates a terminal event in the secretion pathway.

24 d as unfolded substrates through the general secretion pathway.

25 lated exocytosis but not in the constitutive secretion pathway.

26 retromer functions in the same conserved Wnt secretion pathway.

27 YopQ or YopR cleavage products to enter the secretion pathway.

28 structures assembled by the chaperone/usher secretion pathway.

29 s dictate the processing of CTDs by the T9SS secretion pathway.

30 o the periplasm of E. coli by use of the sec secretion pathway.

31 vated macrophages through a vesicle-mediated secretion pathway.

32 may represent a novel stress-induced protein secretion pathway.

33 is a vital component of the general protein secretion pathway.

34 nk between the insulin signaling and insulin secretion pathways.

35 gy to chaperone proteins from other type III secretion pathways.

36 s in the SecB-dependent and SecB-independent secretion pathways.

37 in the regulated (LH) and constitutive (FSH) secretion pathways.

38 e was notable for increases in virulence and secretion pathways.

39 fectors during infection, following distinct secretion pathways.

40 latelet aggregation, spreading, and granular secretion pathways.

41 somally encoded and plasmid-encoded type III secretion pathways act independently.

42 upports the recent demonstration of separate secretion pathways adopted by the two types of particles

43 s been identified as the most common protein secretion pathway among Gram-negative bacteria.

44 occus aureus encodes the Sec-independent Ess secretion pathway, an ortholog of mycobacterial T7 secre

45 Collectively, secretion pathways ancestrally related to bacterial conj

46 ri and Legionella pneumophila - have evolved secretion pathways ancestrally related to conjugation sy

47 e data unveil a novel PKG-dependent platelet secretion pathway and a mechanism by which PKG promotes

48 ototype members of the bacterial two-partner secretion pathway and examples of the expanding number o

49 the immunoglobulin complexes in the default secretion pathway and further increased antibody product

50 the twin-arginine translocase (Tat) protein secretion pathway and likely forms a secretion pore.

51 HMW1 adhesin is secreted via the two-partner secretion pathway and requires HMW1B for translocation a

52 nzae HMW1 adhesin occurs via the two-partner secretion pathway and requires the HMW1B outer membrane

53 lex nature of protein quality control in the secretion pathway and reveal multiple sites that recogni

54 te the effects that clathrin defects have on secretion pathways and plant growth.

55 f several exoenzymes that follow the type II secretion pathway, and decreased virulence.

56 into gastric epithelial cells via a type IV secretion pathway, and on entry into target cells, CagA

57 ing all known components of this alternative secretion pathway are clustered at the same genetic locu

58 Proteins destined to travel this secretion pathway are targeted to the secretion machine

59 d GSP nomenclature and the type II, IV and V secretion pathways are also described to show how they h

60 e ColIb conjugation system and other type IV secretion pathways are discussed.

61 of chylomicrons and chylomicron-independent secretion pathways are expected to be the next frontiers

62 These studies indicate two conserved secretion pathways are initiated by caspase-1, lysosome

63 In several instances protein secretion pathways are similar to those involved in asse

64 gic and enteroaggregative E. coli, but their secretion pathways are unknown.

65 ron, two critical components of the type III secretion pathway, are as efficient as wild-type Salmone

66 y or the main terminal branch of the general secretion pathway, as it has also been referred to, is w

67 e by multiple mechanisms, including specific secretion pathways, autolysis, and membrane vesicle form

68 In these complex secretion pathways, bacterial chaperones direct effector

69 retion system can be modified to travel this secretion pathway by introduction of discrete mutations.

70 stacking protein (GRASP), an unconventional secretion pathway component, is required for Upd2 secret

71 s located in an operon that also encodes Hrp secretion pathway components and is part of the function

72 lla spp. by the zirTS antivirulence genes: a secretion pathway comprised of the outer membrane transp

73 Furthermore, this secretion pathway contributes to flagellar biogenesis an

74 as a substantial impact on astrocyte protein secretion pathways, contributing to motor neuron patholo

75 us intermedius mediate cell contact- and Esx secretion pathway-dependent growth inhibition of diverse

76 two substrates of the first Sec-independent secretion pathway described in M. tuberculosis, which we

77 rophyte) or hrp mutants defective in the Hrp secretion pathway did not induce hin1 significantly.

78 The P. gingivalis contact-dependent protein secretion pathway differs to some extent from type III p

79 U (ExoU), that is delivered via the type III secretion pathway directly into contacting host cells.

80 , and those that lacked a functional Type II secretion pathway displayed nanowires that were poorly c

81 n that is absent in FGF-2 and that the FGF-1 secretion pathway does not restrict the release of high

82 sts that B. anthracis activates the type VII secretion pathway during infection.

83 ; targets include components of the type III secretion pathway, elements involved in envelope and cel

84 cretes the HrpZ harpin by a type III protein secretion pathway encoded by a cluster of hrp (hypersens

85 StcE is secreted by the etp type II secretion pathway encoded on pO157, and extracellular St

86 lus influenzae and are prototype two-partner secretion pathway exoproteins.

87 In gram-negative bacteria, the two-partner secretion pathway exports large, mostly virulence-relate

88 t that the specificity of the stress-induced secretion pathway for FGF-1 involves a carboxyl-terminal

89 MVs function as an alternate secretion pathway for Gram-negative bacteria; therefore,

90 However, the lysosomal-mediated secretion pathways for interleukin-1 beta secretion and

91 Due to differences in cellular sources and secretion pathways for TNF and IFN-gamma, the possibilit

92 that are essential components of the general secretion pathway found in a variety of Gram-negative pa

93 Autotransporter (AT) is a protein secretion pathway found in Gram-negative bacteria featur

94 ymes and toxins using the type II or general secretion pathway, found in a variety of Gram-negative b

95 Due to its secretion via multiple secretion pathways GLUC can find multiple applications a

96 The terminal branch of the general secretion pathway (Gsp or type II secretion system) is u

97 The general secretion pathway (GSP) of Vibrio cholerae is required f

98 The general secretion pathway (GSP), found in a wide range of bacter

99 he main terminal branch (MTB) of the general secretion pathway (GSP).

100 The two-partner secretion pathway has been identified as the most common

101 the target protein at various stages of the secretion pathway has proved to be important.

102 mical dissection of the hrp-encoded type III secretion pathway has revealed new mechanisms by which p

103 etion pathway rather than the SecA-dependent secretion pathway have not yet been identified.

104 negative pathogens, four distinct classes of secretion pathways have been identified that deliver vir

105 Given the essentiality of the general secretion pathway in bacteria and the contribution of vi

106 wo different signal peptides for the protein secretion pathway in Escherichia coli.

107 The two-partner secretion pathway in Gram-negative bacteria consists of

108 etion of proteins via the type II or general secretion pathway in gram-negative bacteria requires the

109 The stimulus-secretion pathway in L-cells is still incompletely under

110 red into host mammalian cells via a type III secretion pathway in pathogenic Yersinia species.

111 and functional components (e.g., Sec vs. Tat secretion pathway in typical nos), and that previous nos

112 lular messengers in islets or other stimulus-secretion pathways in different cells.

113 chaperone pairs are identified from type III secretion pathways in different strains of bacteria.

114 differs to some extent from type III protein secretion pathways in enteric pathogens, as a gene homol

115 essing and the pancreatic beta cell stimulus-secretion pathway including PC1/3, PC2, GLUT-1, glucokin

116 osed whereby rejection of YopE-DHFR from the secretion pathway inhibits type III gene expression.

117 , several Yops are transported by a type III secretion pathway into the host cell cytoplasm.

118 spheroplast formation, indicating that their secretion pathway is accessible to the periplasm or to t

119 The type III secretion pathway is broadly distributed across many par

120 The Esx secretion pathway is conserved across Gram-positive bact

121 ggesting this chromosomally encoded type III secretion pathway is distinct from the flagella secretio

122 A model for the alternate chloride secretion pathway is proposed whereby chloride uptake vi

123 A specialized protein secretion pathway is used by some Gram-negative bacteria

124 system (main terminal branch of the general secretion pathway) is used by diverse gram-negative bact

125 cretion (TPS) is the most widely distributed secretion pathway known.

126 odium falciparum-specific IL-12p70/IFN-gamma secretion pathways known to play a key role in resistanc

127 rain-specific differences in replication and secretion pathways linked to the vector-pathogen interac

128 rogression of tauopathy and that the exosome secretion pathway may be a therapeutic target.

129 ssically been used in studies of the general secretion pathway of Escherichia coli.

130 imilar to precursor protein D of the general secretion pathway of gram-negative bacilli, while the 20

131 The general secretion pathway of gram-negative bacteria is responsib

132 homology to proteins of the type II general secretion pathway of gram-negative bacteria.

133 ialized mode of substrate recognition by the secretion pathway of gram-positive cocci.

134 protein production methods by employing the secretion pathway of serum-free adapted human suspension

135 ating the terminal step in the extracellular secretion pathway of TcpF.

136 acement were constructed and directed to the secretion pathway of the methylotropic yeast Pichia past

137 ich are known to be involved in the type III secretion pathway of virulence proteins.

138 retion pathway is distinct from the flagella secretion pathway of Y. enterocolitica.

139 The type II secretion pathway or the main terminal branch of the gen

140 A novel secretion pathway originally found in plants has recentl

141 on is the designation given to those protein secretion pathways, primarily in pathogenic Gram-negativ

142 We find that a Rab10-based secretion pathway promotes pericellular BM protein accum

143 the secretion of Fap1 to the SecA2-dependent secretion pathway rather than the SecA-dependent secreti

144 nsfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and eff

145 the TTSS-associated chaperones is to confer secretion-pathway specificity to their cognate secreted

146 n A, a well known inhibitor of the classical secretion pathway, suggesting that it follows an unconve

147 To test the hypothesis that the anterograde secretion pathway supplies PM components for retrograde

148 it functions at a later step in the protein secretion pathway than formation of post-Golgi secretory

149 the changes in the lipoprotein assembly and secretion pathway that are caused by 7alpha-hydroxylase.

150 that SecA2-dependent export is a new type of secretion pathway that is part of a virulence mechanism

151 Y. enterocolitica thus has three type III secretion pathways that appear to act independently.

152 Gram-negative bacteria contain multiple secretion pathways that facilitate the translocation of

153 EHEC, including those encoding the type III secretion pathway, the secreted Esp proteins, Tir, and i

154 of bacterial pathogens utilize the type III secretion pathway to deliver effector proteins directly

155 ies use a virulence-plasmid encoded type III secretion pathway to escape the innate immune response a

156 embrane channel component used by the type I secretion pathway to export toxins and other bacterial v

157 identify novel contributions of the type III secretion pathway to post-invasion-specific processes, d

158 ggest that excess soluble A1PiZ transits the secretion pathway to the trans-Golgi network and is sele

159 variety of pathogenic bacteria use type III secretion pathways to translocate virulence proteins int

160 mber of pathogenic bacteria utilize type III secretion pathways to translocate virulence proteins int

161 een EpsE and other components of the type II secretion pathway together with these data further suppo

162 Each secretion pathway was associated with different traffick

163 The Ess (ESX secretion) pathway was previously defined as a genomic c

164 ng protein Cdc42, in the mastoparan stimulus-secretion pathway, was examined.

165 ould help identify substrates of the general secretion pathway, we analyzed the main porin of M. smeg

166 to host cells through the bacterial type III secretion pathway, where it activates disease resistance

167 nce factors are secreted via the two-partner secretion pathway, which consists of an exoprotein calle

168 components of the glucose-dependent insulin secretion pathway whose expression is dependent upon HNF

169 ained unchanged upon blockage of the tubular secretion pathway with probenecid, a necessary condition

170 balancing the anabolic lipoprotein assembly/secretion pathway with the cholesterol catabolic bile ac

171 ence that directly links the Mtb specialized secretion pathway with the evolutionary conserved signal

172 Thus, the Snm secretion pathway works to subvert normal macrophage res