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1 s significantly altered the quality of their secretome.
2 through its diverse metabolite and adipokine secretome.
3 tein in mammals, is actively degraded by the secretome.
4 spectrometry of heart extracts and a fungal secretome.
5 ure from the Mycobacterium marinum bacterial secretome.
6 predominant difference in the pks2(-) mutant secretome.
7 processing of these proteins in the biofilm secretome.
8 ied 11 enriched in the mesenchymal stem cell secretome.
9 ates angiogenic components of the tumor cell secretome.
10 characterization of the B. pseudomallei T2SS secretome.
11 characterized by proteomics analysis of the secretome.
12 -directed EMT activation and Sec23a-mediated secretome.
13 hanisms, including a potent immunomodulatory secretome.
14 port the effect of InhA1 on the B. anthracis secretome.
15 zone and activated to release arrhythmogenic secretome.
16 he inhA1 secretome than in the parent strain secretome.
17 labeling of the C. thermocellum cellulosomal secretome.
18 hemical biology tools for characterizing the secretome.
19 helial traits and Sec23a-mediated tumor cell secretome.
20 changes compared with the normal fibroblast secretome.
21 e media in the presence of the entire Jurkat secretome.
22 hemical biology tools for characterizing the secretome.
23 gulation and the regulation of the mammalian secretome.
24 hologous proteins belong to the core Frankia secretome.
25 racellular matrix components to modulate the secretome.
26 d among the strains, termed the core Frankia secretome.
27 uced growth factors and cytokines in the CMV secretome.
28 ication technology, to comprise the root cap secretome.
29 a key signature in cataloguing the parasite secretome.
30 (CLIC3) is an abundant component of the CAF secretome.
31 h soluble and exosomal fractions of the hMSC secretome.
32 cardial recovery via the components of their secretome.
33 c alterations that include a proinflammatory secretome.
34 categorize the A. fumigatus putative in vivo secretome.
35 g the expression of a complex pro-metastatic secretome.
36 the role of VEGF in modifying the angiogenic secretome.
37 unstressed cells, particularly targeting the secretome.
38 ng several predicted members of the parasite secretome.
39 cells also predicts their cell-type-specific secretome.
40 lineages, despite their diverse genomes and secretomes.
41 cted to specific organs, specific stages, or secretomes.
42 d by the greatest extent in both NSF and SSc secretomes.
43 the relationship between the TIF and plasma secretomes.
44 To better define the L. pneumophila type II secretome, a 2D electrophoresis proteomic approach was u
47 terized, including platelet releasates (the 'secretome'), alpha and dense granules, membrane and cyto
48 ells and/or inhibiting their proinflammatory secretome also improves cardiovascular function, enhance
50 ights into the global beta-cell sheddome and secretome, an important prerequisite to uncover novel me
51 ranscription-PCR (RT-PCR), Western blot, and secretome analyses established that S. Paratyphi A expre
60 co pattern searches to define a pneumococcal secretome and analyzed the transcriptome of the clinical
61 ing components of the differentiating stroma secretome and designed a potential therapeutic strategy
62 mor interstitial fluid (TIF) encompasses the secretome and holds the key to several of the phenotypic
63 a-derived MCSF induces changes in microglial secretome and identified insulin-like growth factor-bind
64 ysin as a major determinant of the S. aureus secretome and identified the phenol-soluble modulins as
65 tant protein-1/chemokine ligand 2 in the MSC secretome and improved MSCs immunosuppressive capacity (
66 of the most abundant proteins of the CyHV-3 secretome and is structurally very similar to carp Il10
68 racterization of the platelet transcriptome, secretome and proteome also suggest that additional func
71 e increased ER-Golgi trafficking, an altered secretome and sensitivity to the retrograde transport in
72 rgoing glutathionylation and apply it to the secretome and the proteome of human monocytic cells.
73 termine interactions between the immune cell secretome and the TRACER-identified active transcription
76 -infected human small airway epithelial cell secretome and was differentially expressed in smaller ai
77 this study, we have examined the M. marinum secretomes and identified four proteins specific to ESX-
78 as well as for expression of the senescence secretome, and (iv) p35 is up-regulated in senescing cel
79 ted with the initial growth medium, isolated secretome, and living bacteria, and characterized for th
80 cellular proteins were identified in the RPE secretome, and only 8 were found to be selectively cleav
81 ructure, was observed in the presence of the secretome, and the rate limiting step of the reaction wa
84 proteins processed by the secretory pathway (secretome) are critical players in the development of mu
85 strate the feasibility of harnessing the MSC secretome as a defined, noncellular strategy to improve
86 nderstanding of the properties of the cancer secretome, as its clinical evaluation may change the the
87 which exocytic vesicles harboring a venomous secretome assembled a sophisticated predatory structure
90 found in individual datasets) and Fugu (14%) secretomes based on analysis of their nearly complete pr
91 parasite Plasmodium falciparum constitute a "secretome" carrying a host-targeting (HT) signal, which
92 greatly aid the annotation of the parasite "secretome" catalog of proteins that are targeted to the
93 inhibition of oncogenic drivers induces vast secretome changes in drug-sensitive cancer cells, parado
96 ing capability, one with a transcriptome and secretome closer to normal fibroblasts (CAF-N) and the o
97 of this tRNA specifically drive synthesis of secretome components, resulting in a type II collagen-ri
98 atory properties are highly variable and the secretome composition following infusion is uncertain.
99 otic mesenchymal stromal cells or with their secretome (conditioned medium) in a transwell system.
101 ry and immunoassays, and found that the HCMV secretome contains over 1,000 cellular proteins, many of
102 transiently controlled antiinflammatory MSC secretome could be achieved at target sites of inflammat
103 tify novel effector proteins, we coupled our secretome data with a machine learning algorithm (SIEVE,
104 in patients with ileal CD, because the PBMC secretomes derived from patients with CD were unable to
106 argeting senescent cells or modulating their secretome for anti-aging therapy may have negative conse
107 supernatants from HCMV-infected cells (HCMV secretomes) for growth factors, by mass spectrometry and
111 compared the expression of secreted factors (secretome) from MDA-PCa-118b and MDA-PCa-133 by cytokine
112 ontrol of secreted factors, and we show that secretome genes are preferentially controlled by synergi
116 Global quantitative analysis of the hypoxic secretome identified lysyl oxidase (LOX) as significantl
118 2 gene products from the wildtype M. marinum secretome in a single CZE-tandem mass spectrometry (MS/M
121 served between the TIF and plasma angiogenic secretomes in triple negative MDA-MB-231 breast cancer x
123 kines were significantly induced in the HCMV secretomes including interleukin-6 (IL-6), granulocyte m
124 s have been developed to characterize these 'secretomes', including the yeast secretion trap (YST) sc
125 tumor microenvironment alter the tumor cell secretome, including those proteins required for tumor g
126 roblasts was also inhibited by S. marcescens secretomes indicating that the effect is not cornea spec
129 herapeutic cells for TBI, and lncRNAs in the secretome is an important mechanism of cell therapy.
131 t of proteins encoded by the genome, and the secretome is the part of it secreted from the cell.
135 present preliminary evidence that the liver secretome may be directly suppressed by PPARalpha, but i
136 gest that celecoxib-driven alteration of the secretome may be involved in some of its clinical side e
138 upregulated MAPK signaling in the pancreatic secretome may reflect the pathophysiological development
140 an et al. propose that ribosomes translating secretome messenger RNAs (mRNAs) traffic from the cytoso
141 ses, and proteases found in the core Frankia secretome might facilitate hyphal penetration through th
142 trated that CMV but not herpes simplex virus secretomes not only induce AG/WH but also promote neoves
143 xpression of secreted cellular proteins (the secretome) occur that have profound effects on host-cell
146 ur analysis revealed an unexpectedly complex secretome of 410 proteins with venomous and lytic but al
148 rometry was used to identify proteins in the secretome of aCPCs and nCPCs, and the literature-based n
150 ete protein spots was altered in the biofilm secretome of an mep72 mutant, including type III secreti
157 identified specific pathways affected by the secretome of CPCs in the setting of myocardial infarctio
159 CXCR2-activating chemokines were part of the secretome of cultured primary benign intestinal adenomas
163 ences the phenotypic characteristics and the secretome of human cardiac progenitor cells (CPCs), and
173 results provide molecular insights into the secretome of P. destructans, and identify serine endopep
175 ysis of many of the effectors comprising the secretome of P. syringae pv tomato DC3000 led to the ide
176 Already, it is evident that the effector secretome of pathogenic oomycetes is more complex than e
177 es of human ileal tissue, we showed that the secretome of peripheral blood mononuclear cells (PBMCs)
178 resented and positionally constrained in the secretome of Phytophthora relative to other eukaryotes.
179 ding enzymes, are integral components of the secretome of Pleurotus ostreatus, a white rot fungus.
180 antitative proteomic approach to analyze the secretome of primary neurons after acute BACE1 inhibitio
181 ibited the production of the proinflammatory secretome of senescent cells using a JAK inhibitor (JAKi
182 as inflammatory mediators that demarcate the secretome of senescent cells, also referred to as the se
186 vation was that GRP-78 was identified in the secretome of these cells and in the bone matrix, suggest
188 uantitative mass spectrometry to compare the secretome of wild-type B. thailandensis to that of a mut
189 sed a proteomic approach to characterize the secretome of X. fastidiosa, both in vitro and in planta,
190 inhibitor I9 domain was more abundant in the secretomes of a wide range of necrotising fungi relative
191 these, Protein S (PROS1) was elevated in the secretomes of all of the androgen-independent prostate c
194 gorithms were used to predict the individual secretomes of each strain, and the set of secreted prote
195 matography-mass spectrometry analysis of the secretomes of encapsulated organisms yielded detailed ge
197 eted by PEL cell lines after comparison with secretomes of human cell lines representative of diverse
199 ld detect structural differences between the secretomes of pancreatic cancer and non-cancerous cells.
200 tudy, we used cytokine arrays to analyze the secretomes of poorly and highly metastatic colorectal ca
203 y a host-targeting (HT) signal present on a "secretome" of hundreds of parasite proteins engaged in r
204 Blood stage malaria parasites target a 'secretome' of hundreds of proteins including virulence d
205 fferences among the extracellular proteomes (secretomes) of three isogenic strains of B. anthracis th
207 s and regional differences in the epithelial secretome participating in RSV lower respiratory tract i
209 omics enabled the identification of a unique secretome pool from these lignocellulose-degrading commu
211 ation in resistin release and the neutrophil secretome profile were observed following exposure to di
213 s in other fungal genomes and found that the secretome profiles cluster the tested basidiomycetes int
214 ce-associated secretory phenotype, and their secretome promotes vascular remodeling and angiogenesis.
216 alysis revealed the interaction of DPSC/SCAP secretome proteins and these proteins were found to be a
219 not exosome-depleted, fractions of the hMSC secretome recapitulated the effects observed with hMSC c
220 r morpholino-based screen for members of the secretome required for vascular development, we identifi
223 f the P. placenta genome, transcriptome, and secretome revealed unique extracellular enzyme systems,
224 sing a proteomics approach with fractionated secretome samples, we were able to identify a spectrum o
228 Eliminating exosomes from the cancer cell secretome, targeting Rab27a, abolished differentiation a
230 ntrast, little is known about changes in the secretome that accompany latent infection, yet this is l
231 dentify proteins from the cardiomyocyte (CM) secretome that are directly targeted by the muscle-speci
233 in mammary fibroblasts induces an oncogenic secretome that remodels the extracellular milieu acceler
234 ADD dependent and identify the TRAIL-induced secretome to drive monocyte polarization to myeloid-deri
235 eceptor on ECs abolished the ability of HCMV secretome to increase survivin expression and activated
238 secretomes with polymyxin B agarose rendered secretomes unable to inhibit epithelial cell migration.
239 SK9-interacting proteins in the HepG2 cells' secretome using co-immunoprecipitation combined with mas
241 oad efficacy or host specificity, a combined secretome was constructed from a monocot specific isolat
244 relevance of the p95HER2-induced senescence secretome, we show that p95HER2-induced senescent cells
246 nctional classification showed that PEL cell secretomes were enriched in proteins specifically involv
247 ts of glutathionylation, particularly in the secretome where the protein concentration is much lower,
249 nce of deleterious OIS- or TIS-related tumor secretomes, which can promote both drug resistance and t
250 dentified as up-regulated in the prfA(L140F) secretome, while the secretion of two proteins was found
252 Here we review the Bordetella virulence secretome with an emphasis on factors that translocate i
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