ライフサイエンスコーパス: secretory component

1 ways, plus glycans present on the antibody's secretory component.

2 associated with a 70-kDa glycoprotein called secretory component.

3 ctor H (FH) and secretory IgA (sIgA) via the secretory component.

4 r binding of human J chain-containing IgA to secretory component.

5 osinophil interactions with secretory IgA or secretory component.

6 is showed that eosinophils bound to purified secretory component.

7 uantitative immunoblotting using Abs against secretory component.

8 her spot was identified as the transmembrane secretory component.

9 ved polymeric IgA and IgM with a recombinant secretory component.

10 SecA/SecYEG pathways, suggesting they share secretory components.

11 This preferential interaction between secretory component and eosinophils may provide a novel

12 Anti-meningococcal C-specific secretory component and IgA antibody titers were closely

13 overlay assays, we found that ricin bound to secretory component and the H chain of human IgA, and th

14 henotypes are enhanced by mutations in other secretory components and are at least partially overcome

15 organized into two operons, one encoding the secretory components and the other encoding the structur

16 of desialylation included human lactoferrin, secretory component, and IgA2 that were shown to be pres

17 s in the calf intestine, while the flagellar secretory components are also necessary for the inductio

18 These vesicles appear to have a secretory component, as QPP is secreted in a functionall

19 Secretory component bound to IgA mediates transepithelia

20 production stimulated with secretory IgA or secretory component but not with serum IgA, suggesting a

21 ound that monoclonal IgA Abs with or without secretory component, but not IgG or IgM Abs, bound to th

22 bacterial OPC than did mIgA, indicating that secretory component does not hinder the effect of comple

23 bacterial IgA1 protease, demonstrating that secretory component does not prevent the proteolytic deg

24 Gentle partial deglycosylation of the SIgA secretory component enhanced susceptibility to proteolys

25 5 KO mice had normal expression of other key secretory components; however, stimulation-dependent sec

26 cific immunoglobulin A (IgA), IgA1, IgA2 and secretory component, IgG antibodies, and total IgG and I

27 S. aureus to include DMBT1(gp-340), mucin-7, secretory component, immunoglobulin A, immunoglobulin G,

28 n isotype and that the sputum IgA contains a secretory component, indicating that it is locally produ

29 nflammation, demonstrating that IgA bound to secretory component is not necessary for the development

30 f VHH-IgA with the porcine joining chain and secretory component led to the production of light-chain

31 of lung epithelia but was essential for the secretory component of phospholipid synthesis and critic

32 that bacteria from IgA-low mice degrade the secretory component of secretory IgA as well as IgA itse

33 most apparent on the heavily N-glycosylated secretory component of the antibody.

34 ultant secretory IgA; however, the effect of secretory component on the biologic activity of IgA is u

35 cretory component was inhibited by unlabeled secretory component or secretory IgA but not by serum Ig

36 statherins, and histatins but not MG1, sIgA, secretory component, or cystatins.

37 ptional regulators (hilA and invF), type III secretory components (orgA, invG and spaR) and secreted

38 Thus, secretory component plays important roles in activating

39 igh-molecular-weight forms of IgA-containing secretory component predominated in all saliva samples.

40 Here, we report that secretory IgA and secretory component preferentially activate human eosino

41 blotting with specific antibodies to IgA and secretory component revealed that secretory IgA (SIgA) d

42 of a single-chain Fv directed against human secretory component (SC) and linked to human alpha(1)-AT

43 IgA receptor (pIgA-R) and redistribution of secretory component (SC) from bile to blood.

44 st pathogens targeting mucosal surfaces, and secretory component (SC) fulfills multiple roles in this

45 varying time intervals, and RCMV titers and secretory component (SC) levels in media or cell extract

46 from human plasma is able to associate with secretory component (SC) to generate SIgA-like molecules

47 chains produced by the plasma cells, whereas secretory component (SC), a cleavage product of the poly

48 Ig containing an unusual extra polypeptide, secretory component (SC), added during transcytosis thro

49 A2 synthesis, pIgR expression, production of secretory component (SC), IgA and relevant IgA antibodie

50 IL-4 and IFN-gamma increase release of secretory component (SC), the polymeric IgA (plgA)-bindi

51 Western blot analysis with an Ab to secretory component (SC), the portion of the pIgR that r

52 roteolytic cleavage releases the ectodomain (secretory component [SC]) as an integral component of se

53 al secretions, where the cleaved ectodomain (secretory component; SC) becomes a component of secretor

54 was enhanced synergistically by immobilized secretory component; secretory component showed no effec

55 stically by immobilized secretory component; secretory component showed no effect on neutrophil activ

56 anti-HIV IgA was frequently associated with secretory component, suggesting transepithelial transpor

57 Secretory component, the cleaved epithelial receptor for

58 isting of a single-chain Fv directed against secretory component, the extracellular portion of the pI

59 Here by binding human secretory component to overlapping decapeptides of Calph

60 biological functions for trout pIgR or trout secretory component (tSC) remain unknown.

61 The binding of 125I-labeled secretory component was inhibited by unlabeled secretory

62 The distribution of axonal secretory components was evaluated in axons of the sciat