ライフサイエンスコーパス: sedatives

1 e mechanically ventilated and were receiving sedatives.

2 people who find it hard to get to sleep take sedatives.

3 a reduces the metabolism of commonly used IV sedatives.

4 nes suggest minimizing dosage of opioids and sedatives.

5 to find non-benzodiazepine-based alternative sedatives.

6 d clinical outcomes associated with specific sedatives.

7 be unintentionally induced by heavy doses of sedatives.

8 pplemental narcotics (5 mg of oxycodone) and sedatives (1 mg lorezapam), and one patient became apnei

9 ics, 3) antidepressants, 4) street drugs, 5) sedatives, 6) poisoning (carbon monoxide, arsenic, or cy

10 Daily interruption of sedatives alleviates these problems, but the impact of t

11 rug events reported to occur with the use of sedatives, analgesics, and antipsychotics in the intensi

12 of life-sustaining treatment and the use of sedatives, analgesics, and nonpharmacologic approaches t

13 propofol alone or in combination with other sedatives/analgesics has become popular for procedural s

14 The mean dose of sedatives and analgesics administered nearly doubled as

15 How critical care practitioners prescribe sedatives and analgesics and, perhaps more broadly, how

16 An evidence-based approach to administering sedatives and analgesics is necessary to optimize short-

17 ill patients receive significant amounts of sedatives and analgesics that increase their risk of dev

18 Critically ill patients are prescribed sedatives and analgesics to decrease pain and anxiety, i

19 of sedation and analgesia and total doses of sedatives and analgesics.

20 documented the advantages of pharmacological sedatives and anesthetics for use in bronchoscopy.

21 Despite the common use of sedatives and anesthetics in the acute phase of TBI mana

22 of GABA(A) receptor activity and are potent sedatives and anesthetics.

23 The use of sedatives and antibiotics may be required to be changed

24 mmonly used ICU medications, especially some sedatives and anticholinergic medications, and keeping p

25 Active compounds included sedatives and antipsychotic, antidepressant, and antisei

26 ely, compared with 3.6 (95% CI, 3.2-4.1) for sedatives and anxiolytics, 2.9 (95% CI, 2.3-3.5) for sti

27 idepressants, antipsychotics, lithium salts, sedatives and anxiolytics, and stimulants.

28 Sedatives and anxiolytics, antidepressants, antipsychoti

29 As an alternative to high-dose sedatives and controlled mechanical ventilation, pharmac

30 ngton, Minnesota, USA) and novel 'soft-drug' sedatives and hypnotics (e.g. CNS-7259X and TD-4756) as

31 bilitation in routine care, including use of sedatives and lack of awareness of post-ICU cognitive im

32 The use of sedatives and neuromuscular blocking agents in the ICU i

33 daily dose, and route of administration for sedatives and neuromuscular blocking agents were abstrac

34 We compared the doses and duration of sedatives and opioid analgesics in patients receiving lo

35 Sedatives and opioids use was similar in the higher and

36 Sedatives and opioids were used in >80% of the patients

37 The use of sedatives and opioids, but not NMBAs, was associated wit

38 The use of sedatives and opioids, but not the use of NMBAs, was ass

39 outcomes included duration of stay, doses of sedatives and opioids, unintentional device removal, del

40 se of continuous infusions of opioids and/or sedatives and ventilator parameters (tidal volume per id

41 Sedatives and/or analgesics were administered to 47 (89%

42 ting for relevant covariates including coma, sedatives, and analgesics in patients receiving mechanic

43 Decisions to administer opioids, sedatives, and antipsychotic medications are frequently

44 ill patients frequently receive analgesics, sedatives, and antipsychotics to optimize patient comfor

45 armacologic treatments including analgesics, sedatives, and neuromuscular blockers.

46 The use and effectiveness of analgesics, sedatives, and NMJBs, as well as cost and outcomes, were

47 gical ocular complication rates, use of oral sedatives, and reported reasons to perform the surgery i

48 prescription drugs (prescription pain pills, sedatives, and tranquilliser) were the most commonly rep

49 antiinfective agents, estrogens, progestins, sedatives, anticonvulsant drugs, or drugs that may form

50 he GABAA receptor are important anesthetics, sedatives, anticonvulsants, and anxiolytics.

51 ys compared with intermittent lorazepam when sedatives are interrupted daily.

52 General anesthetics and sedatives are used in millions of children every year to

53 to receive higher doses of both opioids and sedatives as they get closer to death.

54 dverse events and route of administration of sedatives as well as image quality.

55 Among those receiving the sedatives, benzodiazepine and propofol doses were increa

56 re widely used as anti-pruritics and central sedatives, but demonstrate only modest anti-inflammatory

57 preexisting cognitive impairment, and use of sedatives; but to date, the relationship between race an

58 ows that subjects rendered unresponsive with sedatives do not exhibit a stereotypic 'unconscious' res

59 itoring of anesthetic depth for titration of sedatives, en route to avoiding emetogenic and hyperalge

60 Sedatives, even given intermittently, substantially redu

61 Intravenous sedatives examined included benzodiazepines (midazolam a

62 estational age, sex, PMA, dose of analgesics/sedatives (fentanyl, morphine, midazolam), mechanical ve

63 %) were reported as the most frequently used sedatives; fentanyl (44%) and morphine (20%) the most fr

64 onist medications are the most commonly used sedatives for intensive care unit (ICU) patients, yet pr

65 ologists and other specialists administering sedatives for their own or others' procedures.

66 ration following exposure to anesthetics and sedatives has been clearly established in developing ani

67 Some anesthetics and sedatives have been shown to cause neurotoxic effects in

68 (HR, 1.22; 95% CI, 1.08 to 1.37), hypnotics/sedatives (HR, 1.21; 95% CI, 1.07 to 1.37), antidepressa

69 (HR, 1.33; 95% CI, 1.16 to 1.52), hypnotics/sedatives (HR, 1.24; 95% CI, 1.07 to 1.43), GI drugs (HR

70 Particularly addressing the fields of sedatives, hypnotics and neuromuscular blockers, however

71 Patients may use sedatives, hypnotics, or alcohol in an effort to interru

72 al ventilation (TV) and exposure to opioids, sedatives-hypnotics, or general anaesthetics in neonates

73 plications related to the use of opioids and sedatives in an elderly population.

74 anically ventilated adult patients receiving sedatives in an ICU setting were used to develop and tes

75 xmedetomidine and propofol are commonly used sedatives in neurocritical care as they allow for freque

76 evidence for patterns of use of opioids and sedatives in palliative care and examine whether the doc

77 ssociated with increased dose or duration of sedatives in patients with acute lung injury.

78 information and the wide spread use of both sedatives in routine practice the pharmacovigilance plan

79 reatment, or increases in dose of opioids or sedatives, is associated with precipitation of death.

80 ostoperative management strategy that avoids sedatives, muscle relaxants, and physical restraints, an

81 as no higher rate of infection or the use of sedatives, narcotics, or antibiotics in the catheter gro

82 rtant anatomic site mediating the effects of sedatives on naturally occurring sleep.

83 The effects of sedatives on portal pressure measurements have not yet b

84 m, coma, sepsis, mechanical ventilation, and sedatives/opiates.

85 dence (marijuana, cocaine, other stimulants, sedatives, opioids), or habitual smoking at first interv

86 The use of sedatives, opioids, and neuromuscular blocking agents (N

87 her positive end-expiratory pressure (PEEP), sedatives, opioids, and NMBAs are used in a higher propo

88 ively collected data regarding the impact of sedatives, opioids, and NMBAs in ALI/ARDS patients on du

89 e percentage of study days patients received sedatives, opioids, or neuromuscular blockade.

90 lness, comorbid conditions, coma, and use of sedatives or analgesic medications), delirium was indepe

91 Clinicians frequently escalate the dose of sedatives or analgesics to dying patients as life-sustai

92 The use of analgesics, sedatives, or extubation did not significantly influence

93 akes/outputs, requirements for vasopressors, sedatives, or neuromuscular blocking agents, percentage

94 Female gender (p = .019), the absence of sedatives (p = .009), and lower Acute Physiology and Chr

95 ver, this may be reduced during sleep and by sedatives, potent analgesics, and volatile anesthetics.

96 cost-effectiveness of the most commonly used sedatives prescribed for mechanically ventilated critica

97 for marijuana to 0.63 (CI, 0.47 to 0.78) for sedatives; specificity was 0.93 or higher.

98 atients, due to a combination of illness and sedatives, spend a considerable amount of time in a coma

99 endence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates was assessed at perso

100 nt probands for cocaine, marijuana, opiates, sedatives, stimulants, and tobacco.

101 se, and abuse of and dependence on cannabis, sedatives, stimulants, cocaine, opiates, and hallucinoge

102 actor that underlies the abuse of marijuana, sedatives, stimulants, heroin or opiates, and psychedeli

103 Abrupt discontinuation of use of sedatives such as benzodiazepines and ethanol can also p

104 als, all currently available anesthetics and sedatives that have been studied, such as ketamine, mida

105 se results could help with the design of new sedatives that induce a more natural sleep.

106 tibility and insensitivity to benzodiazepine sedatives through an effect on gene transcription.

107 However, like all sedatives, volatile agents are capable of deeply sedatin

108 Sedatives were administered in 85% of 18,050 four-hour i

109 Sedatives were also associated with increased time to ac

110 Critically ill patients often receive sedatives, which may delay liberation from mechanical ve

111 Evaluation II score and cumulative doses of sedatives while comatose.

112 nned to compare midazolam and clonidine, two sedatives widely used within PICUs neither of which bein

113 aneous awakening trials (ie, interruption of sedatives) with daily spontaneous breathing trials resul

114 ning trials (SATs)-ie, daily interruption of sedatives-with spontaneous breathing trials (SBTs).