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1 opus development and establishing Drosophila segment polarity.
2 s (fss), because its paraxial mesoderm lacks segment polarity.
3 ream of Hh signaling in the establishment of segment polarity.
4 The mutants also display evidence of segment polarity.
5 that oro functions in determining embryonic segment polarity.
6 and nerves is perturbed, indicating loss of segment polarity.
7 ecursor has a distinct identity conferred by segment polarity and dorso-ventral patterning genes that
11 ophila Chibby by RNA interference results in segment polarity defects that mimick a wingless gain-of-
13 recently published Boolean network model of segment polarity development in Drosophila melanogaster.
18 (Dvl2) gene is an ortholog of the Drosophila segment polarity gene Dishevelled, a member of the highl
19 ne of three mouse homologs of the Drosophila segment polarity gene Dishevelled, were created by gene
21 characterizing the expression pattern of the segment polarity gene engrailed (en) in a basal annelid,
22 es En-1 and En-2, homologs of the Drosophila segment polarity gene engrailed, in regulating the devel
26 and stripe-specific defects in pair-rule and segment polarity gene expression.fish mutant embryos als
28 en the embryos, a hierarchy of gap/pair-rule/segment polarity gene function may be a shared and ances
29 growth factors); Wnt 7a and Shh (Drosophila segment polarity gene homologs); Msx-1 and Msx-2 (Msx cl
31 a hierarchy of maternal, gap, pair-rule, and segment polarity gene interactions regulates virtually s
33 n somite is repressed in mice mutant for the segment polarity gene Mesp2 and expanded in Splotch muta
36 Drosophila melanogaster, was identified as a segment polarity gene necessary for the transduction of
37 portant insights into the functioning of the segment polarity gene network, such as the crucial role
39 esent genetic evidence showing that lines, a segment polarity gene of Drosophila, is required for the
41 the human homologue (PTCH) of the Drosophila segment polarity gene patched have been identified in NB
42 of the mammalian homologue of the Drosophila segment polarity gene patched, is a receptor for hedgeho
48 Dvl genes are homologs of the Drosophila dsh segment polarity gene, and are involved in the Wnt/wingl
49 others have recently characterized a second segment polarity gene, dTCF or pan, 12 kb upstream of ci
50 lving mammalian homologues of the Drosophila segment polarity gene, patched (ptc) and its ligand, son
51 luding the human homologue of the Drosophila segment polarity gene, patched (PTCH), the adenomatous p
56 tern resembles the expression stripes of the segment-polarity gene engrailed, which has a key role in
58 h), a vertebrate homologue of the Drosophila segment-polarity gene hedgehog, has been reported to pla
61 show that naked cuticle (nkd), a Drosophila segment-polarity gene, encodes an inducible antagonist f
64 Along the anterior-posterior axis, several segment polarity genes (wingless, engrailed, hedgehog, a
65 parallel: a cell fate programme mediated by segment polarity genes and a boundary/epithelial integri
66 omologues may not control segmentation, some segment polarity genes and their interactions are conser
68 In the trunk of the Drosophila embryo, the segment polarity genes are initially activated by the pa
70 ng computer simulations, that the Drosophila segment polarity genes constitute such a module, and tha
71 ectly control the periodic expression of the segment polarity genes engrailed (en) and wingless (wg)
72 tory effects of otd on the expression of the segment polarity genes engrailed (en) and wingless (wg).
73 l expression of orthologues of the arthropod segment polarity genes engrailed (en), hedgehog (hh), an
74 e mutants fail to maintain expression of the segment polarity genes engrailed (en), wingless (wg), an
76 roduction of secreted signals encoded by the segment polarity genes hedgehog (hh) and wingless (wg) a
79 secondary pair-rule genes directly regulate segment polarity genes in Drosophila, we analyzed Tc-prd
82 rovided by its genetic interactions with the segment polarity genes patched (ptc) and fused (fu).
84 segments and segments, via the regulation of segment polarity genes such as gooseberry, which in turn
86 s required for the correct expression of the segment polarity genes wingless, engrailed and gooseberr
87 ir-rule gene products subsequently 'imprint' segment polarity genes with reiterated patterns, thus de
88 the expression of the gap, segmentation and segment polarity genes, as well as changes in early morp
89 e epidermal pattern in each segment, several segment polarity genes, including gooseberry (gsb), spec
90 our methods to the regulatory network of the segment polarity genes, thus gaining novel insights into
94 dulates the Runt-dependent regulation of the segment-polarity genes wingless (wg) and engrailed (en).
96 lishing stripes of expression of several key segment-polarity genes, one stripe for each parasegment,
97 nvey positional information to pair-rule and segment-polarity genes, the latter forming a segmental p
100 presentatives of coordinate, gap, pair-rule, segment polarity, homeotic, and Polycomb group functions
101 the leech primary blast cell clones acquire segment polarity - i.e. a fixed sequence of positional v
103 s study by showing that the establishment of segment polarity in the leech ectoderm is largely indepe
104 gs gave rise to a model for the formation of segment polarity in the zebrafish in which caudal is the
108 at these genes function at the pair-rule and segment polarity levels to establish the spacing and pol
109 even pair-rule stripes, but later exhibits a segment polarity-like pattern for which no phenotypic co
110 ular mechanisms underlying somite formation, segment polarity, maintenance of segment borders, and th
112 We showed previously that a model of the segment polarity network in Drosophila is robust to para
113 three models of biochemical regulation: the segment polarity network in Drosophila melanogaster, the
115 omparable to the highly conserved ectodermal segment polarity pattern observed in arthropods at any l
117 encing of dally-like, but not dally, gives a segment polarity phenotype identical to that of null mut
119 es of this gene, mutant embryos develop with segment polarity phenotypes reminiscent to loss of eithe
120 y late morphogenetic role for this and other segment polarity proteins, mainly oriented at lobule jun
121 led expression play an important role in the segment polarity specification of the Drosophila embryo,
122 owever, while we observe nmr1 transcripts in segment polarity stripes and specific neural precursors
123 otein are expressed in identical patterns of segment polarity stripes, defined sets of neuroblasts, m
124 omplications for dissecting the pair-rule to segment-polarity transition are the regulatory interacti
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