ライフサイエンスコーパス: segment polarity gene

1 we have identified rasp, a novel Drosophila segment polarity gene.

2 d gap genes into the segmental expression of segment polarity genes.

3 ised of maternal effect, gap, pair-rule, and segment polarity genes.

4 segments has not been defined for any of the segment-polarity genes.

5 parallel: a cell fate programme mediated by segment polarity genes and a boundary/epithelial integri

6 omologues may not control segmentation, some segment polarity genes and their interactions are conser

7 Dvl genes are homologs of the Drosophila dsh segment polarity gene, and are involved in the Wnt/wingl

8 These segment polarity genes are expressed in some, but not al

9 In the trunk of the Drosophila embryo, the segment polarity genes are initially activated by the pa

10 To understand how these segment polarity genes are regulated, we examined the re

11 the expression of the gap, segmentation and segment polarity genes, as well as changes in early morp

12 ng computer simulations, that the Drosophila segment polarity genes constitute such a module, and tha

13 The Drosophila segment polarity gene cubitus interruptus (ci) encodes a

14 The segment polarity gene cubitus interruptus (ci) maps to t

15 Hh signaling is thought to involve the segment polarity gene cubitus interruptus (ci).

16 (Dvl2) gene is an ortholog of the Drosophila segment polarity gene Dishevelled, a member of the highl

17 ne of three mouse homologs of the Drosophila segment polarity gene Dishevelled, were created by gene

18 others have recently characterized a second segment polarity gene, dTCF or pan, 12 kb upstream of ci

19 x-3, is key to the coordinated regulation of segment-polarity genes during embryogenesis.

20 show that naked cuticle (nkd), a Drosophila segment-polarity gene, encodes an inducible antagonist f

21 The expression domains of the segment polarity gene engrailed (en) allow one to subdiv

22 characterizing the expression pattern of the segment polarity gene engrailed (en) in a basal annelid,

23 es En-1 and En-2, homologs of the Drosophila segment polarity gene engrailed, in regulating the devel

24 One example is the expression of the segment polarity gene engrailed, which at embryonic and

25 ectly control the periodic expression of the segment polarity genes engrailed (en) and wingless (wg)

26 tory effects of otd on the expression of the segment polarity genes engrailed (en) and wingless (wg).

27 l expression of orthologues of the arthropod segment polarity genes engrailed (en), hedgehog (hh), an

28 e mutants fail to maintain expression of the segment polarity genes engrailed (en), wingless (wg), an

29 The segment-polarity gene Engrailed and the homeotic genes U

30 tern resembles the expression stripes of the segment-polarity gene engrailed, which has a key role in

31 rect role in repressing transcription of the segment-polarity gene engrailed.

32 We report that primary segment polarity genes (engrailed, hedgehog and wingless

33 To determine whether segment polarity gene expression is established differen

34 These results show that segment polarity gene expression is necessary for the su

35 and stripe-specific defects in pair-rule and segment polarity gene expression.fish mutant embryos als

36 Previous studies of segment polarity gene function largely focused on neurob

37 en the embryos, a hierarchy of gap/pair-rule/segment polarity gene function may be a shared and ances

38 We also provide evidence that the segment-polarity gene, gooseberry (gsb), controls expres

39 Segment polarity genes have a dual function in early neu

40 roduction of secreted signals encoded by the segment polarity genes hedgehog (hh) and wingless (wg) a

41 We show that the segment polarity genes hedgehog and wingless specify the

42 h), a vertebrate homologue of the Drosophila segment-polarity gene hedgehog, has been reported to pla

43 growth factors); Wnt 7a and Shh (Drosophila segment polarity gene homologs); Msx-1 and Msx-2 (Msx cl

44 The segment polarity gene homologues have a conserved role i

45 of the Drosophila melanogaster pair rule and segment polarity genes in a range of arthropods.

46 secondary pair-rule genes directly regulate segment polarity genes in Drosophila, we analyzed Tc-prd

47 e epidermal pattern in each segment, several segment polarity genes, including gooseberry (gsb), spec

48 a hierarchy of maternal, gap, pair-rule, and segment polarity gene interactions regulates virtually s

49 ch head segment exhibits a unique network of segment polarity gene interactions.

50 Expression of the Drosophila segment polarity genes is initiated by a pre-pattern of

51 n somite is repressed in mice mutant for the segment polarity gene Mesp2 and expanded in Splotch muta

52 Here we show that the segment polarity gene midline is required for neuroblast

53 Hence, the segment polarity genes midline and H15 play an important

54 In Drosophila, hedgehog is one of the segment-polarity genes, mutations of which disrupt the p

55 The Drosophila segment polarity gene naked cuticle (nkd) encodes an EF

56 Drosophila melanogaster, was identified as a segment polarity gene necessary for the transduction of

57 portant insights into the functioning of the segment polarity gene network, such as the crucial role

58 Here we describe a new segment polarity gene of Drosophila melanogaster, oroshi

59 esent genetic evidence showing that lines, a segment polarity gene of Drosophila, is required for the

60 lishing stripes of expression of several key segment-polarity genes, one stripe for each parasegment,

61 tions of the human homolog of the drosophila segment polarity gene patched (ptc).

62 the human homologue (PTCH) of the Drosophila segment polarity gene patched have been identified in NB

63 of the mammalian homologue of the Drosophila segment polarity gene patched, is a receptor for hedgeho

64 y of protein kinase A and the product of the segment polarity gene patched.

65 rovided by its genetic interactions with the segment polarity genes patched (ptc) and fused (fu).

66 lving mammalian homologues of the Drosophila segment polarity gene, patched (ptc) and its ligand, son

67 luding the human homologue of the Drosophila segment polarity gene, patched (PTCH), the adenomatous p

68 arity to the hereditary basal cell carcinoma/segment polarity gene, patched.

69 otein with strong homology to the Drosophila segment polarity gene, patched.

70 e proteins closely related to the Drosophila segment polarity gene product armadillo.

71 imary pair-rule transcription factor Runt in segment-polarity gene regulation.

72 Drosophila patched is a segment polarity gene required for the correct patternin

73 Here we show that the segment-polarity gene smoothened is required for the res

74 While the expression patterns of segment polarity genes such as engrailed have been shown

75 segments and segments, via the regulation of segment polarity genes such as gooseberry, which in turn

76 nvey positional information to pair-rule and segment-polarity genes, the latter forming a segmental p

77 our methods to the regulatory network of the segment polarity genes, thus gaining novel insights into

78 We have expressed the segment polarity gene wingless (wg) ectopically in imagi

79 The Drosophila segment polarity gene wingless (wg) is essential for cel

80 The expression patterns of the segment polarity genes wingless and engrailed are conser

81 s required for the correct expression of the segment polarity genes wingless, engrailed and gooseberr

82 dulates the Runt-dependent regulation of the segment-polarity genes wingless (wg) and engrailed (en).

83 Along the anterior-posterior axis, several segment polarity genes (wingless, engrailed, hedgehog, a

84 ir-rule gene products subsequently 'imprint' segment polarity genes with reiterated patterns, thus de