ライフサイエンスコーパス: selection

1 librium is determined by frequency-dependent selection.

2 justification for bovine and porcine target selection.

3 occurred rapidly (10 ms) without prior mass-selection.

4 me response was influenced by reference site selection.

5 evolution of genomes in response to natural selection.

6 ir local environments as a result of natural selection.

7 under short day and exhibits a signature of selection.

8 nigrostriatal dopamine biases ongoing action selection.

9 rames (ORFs) that appear to be under relaxed selection.

10 e of Darwin's theory of evolution by natural selection.

11 iated with susceptibility were under neutral selection.

12 ence the population dynamics and thus future selection.

13 ection, but might also be shaped by negative selection.

14 unction have undergone positive evolutionary selection.

15 as classic exemplars of evolution by natural selection.

16 cted breeding values in the absence of local selection.

17 r domains need to be evolved through natural selection.

18 variations that subject the cells to natural selection.

19 r the TRN in arousal, attention, and sensory selection.

20 hanges when populations experience stringent selection.

21 iated with how complexity influences habitat selection.

22 re-entry to ensure efficient affinity-based selection.

23 prophages, which are actively eliminated by selection.

24 ve and serial rounds of clonal expansion and selection.

25 iding a function that is targeted by natural selection.

26 e under 0.25 and 0.5 microg/ml virginiamycin selections.

27 -N-nitro-N-nitroso-guanidine mutagenesis and selection, a mutant strain Apmu4 was derived, in which t

28 Variation in sexual selection across a species range, especially across a gr

29 ND5 genes against a background of purifying selection across the mitogenome.

30 independent cells that are poised for clonal selection after androgen-deprivation therapy.

31 and cellular applications including the (a) selection against various target molecules; (b) modulati

32 Many miRNAs selected by our feature selection algorithm had strong previous associations to

33 their highly compliant criteria for sequence selection allows them to be modified to incorporate prot

34 rop rotational effects in maize will promote selection and adoption of favorable crop rotation sequen

35 Transcription start-site (TSS) selection and alternative promoter (AP) usage contribute

36 Codon-based analyses of selection and assessments of changes in amino acid prope

37 egulatory signaling in APCs regulates B cell selection and autoimmunity.

38 epialleles, which are transmissible through selection and breeding.

39 utionarily recent sRNAs can be acted upon by selection and contribute to the evolution of phenotypic

40 gether, results show that multicriteria site selection and deliberate planning of interconnections ma

41 le in enhancing current understanding of how selection and demography can impact phenotypes.

42 reduce morbidity and mortality include rapid selection and distribution of effective antimicrobial ag

43 The connector enables selection and download of DICOM images and associated re

44 on laboratories, but best practices for case selection and for maximizing the effectiveness of peer r

45 s approaches to estimate the contribution of selection and genetic drift, and their interplay, to the

46 us impact of environmental variation on both selection and genetic variation are especially scarce.

47 How do environmental conditions influence selection and genetic variation in wild populations?

48 the computational cost and facilitate model selection and inference.

49 e interval for re-resection for both patient selection and long-term survival is not known.

50 these studies can be problematic since both selection and neutral demographic events can create simi

51 sed on the molecular details of the bud site selection and polarity establishment, not much is known

52 for polyST autopolysialylation in substrate selection and polySia chain elongation.

53 orative Cooling, which uses Relief-F feature selection and random forest classification.

54 ion of T cells that are capable of surviving selection and recognizing foreign antigen.

55 ct key evolutionary processes such as sexual selection and sexual conflict.

56 NDTISE is much better than random selection and slightly outperforms NCPIS.

57 yping to assess antimalarial drug resistance selection and spread in the Greater Mekong subregion.

58 ree search, resulting in higher quality move selection and stronger self-play in the next iteration.

59 ) thymocytes, has a crucial role in positive selection and T cell development.

60 ral structural proteins for integration site selection and the avoidance of genomic junkyards.

61 ificity results from a combination of steric selection and the presence of a P-H...pi interaction bet

62 ork is trained to predict AlphaGo's own move selections and also the winner of AlphaGo's games.

63 s the genetic diversity required for natural selection, and enables the extensive phenotypic diversit

64 distinct mechanisms for attention guidance, selection, and enhancement during visual search, instead

65 ionary mechanisms, such as mutation, natural selection, and genetic drift, and also the interactions

66 nthesize phosphothreonine in cells with this selection approach, we discover a phosphothreonyl-tRNA s

67 Using a random mutagenesis and growth selection approach, we identified amino acid substitutio

68 dundancy - maximum relevance (TMRMR) feature selection approach, which is able to handle multivariate

69 nearity, to a traditional backwards variable selection approach.

70 Target identification and contact selection are known contributors to variability in effic

71 Task and response selection are strongly interactive: it is more difficult

72 mitochondria, yet the rules that govern this selection are unclear.

73 pharmacokinetics, and safety, leading to its selection as the preferred development candidate.

74 nd highlight genetic variation indicative of selection at specific genes.

75 independent researchers performed the study selection based on consensus.

76 wise dimension reduction and texture feature selection based on reproducibility, machine learning, an

77 Bayesian model selection between exponential and gamma distributions fo

78 ional propensity scores were used to address selection bias for a retrospective cohort study of child

79 The extent of selection bias was determined by the magnitudes of genet

80 y, false-positive rates were not affected by selection bias.

81 gene clusters controlling key traits during selection breeding in Europe and China.

82 t by adaptive protein evolution or balancing selection, but by extensive hitchhiking of linked varian

83 of various mutational processes and positive selection, but might also be shaped by negative selectio

84 ) signaling in the thymus initiates positive selection, but the CD8(+)-lineage fate is thought to be

85 value of the rewards received per se, rather selection by a human agent was key to reciprocity.

86 The results establish the mechanism of TSS selection by bacterial RNAP and suggest a general mechan

87 RNAP and suggest a general mechanism for TSS selection by bacterial, archaeal, and eukaryotic RNAP.

88 dendritic cells, and potential prion strain selection by CD21/35 and fH.

89 Habitat selection by colonizing organisms is an important factor

90 sequence, particularly in cell culture where selection can be used to recover relatively rare homolog

91 s an overlooked process by which fluctuating selection can occur in nature, suggesting that fluctuati

92 In many ecosystems, natural selection can occur quickly enough to influence the popu

93 The findings demonstrate that parallel ELT selections can be used to assess ligandability and highl

94 The relative impact of selection, chance and history will determine the predict

95 present evidence that the targets of natural selection change over time, as epistasis and historical

96 t, Drosophila, mice, and humans, the average selection coefficient becomes more deleterious with incr

97 maintained by strong selection, the average selection coefficient for most nonparasitic genes is low

98 lations further demonstrate how active scale selection controls mirror-symmetry breaking and the emer

99 thereby increasing phenotypic variation that selection could act on and facilitating adaptive evoluti

100 al trkB is essential to goal-directed action selection, countering habit-based behavior otherwise fac

101 Four randomized clinical trials met the selection criteria and included 1874 unique patients; 93

102 In our response, we detail our selection criteria for reference maps, which clarify why

103 human ventricle, which, along with specific selection criteria, allows for a direct visualization of

104 ty dimension, used methods to expedite study selection, data extraction, and quality assessment, and

105 meters: (1) an expansion length beyond which selection dominates over genetic drift; (2) a characteri

106 he patterns observed necessitate a degree of selection driven by the introduction of PfHRP2-based RDT

107 the striatum is integral to efficient action-selection during foraging.SIGNIFICANCE STATEMENT Evoluti

108 , we did not detect any strong signatures of selection during replication in macaques.

109 two interacting processes account for module selection during sensorimotor control and learning.

110 ineage-specifying cytokines' during positive selection eliminated Runx3d expression and completely ab

111 classifiers combined with different feature selection encoding schemes.

112 To assess current nationwide case selection factors for minimally invasive distal pancreat

113 e c-Kit(+) population is further enriched by selection for a CD133(+) endothelial progenitor cell pop

114 tion for high rate of biosynthesis implies a selection for aerobic glycolysis and uncoupling biosynth

115 primates were subjected to enhanced positive selection for bright-light vision and relatively weak se

116 th differing levels of sexually antagonistic selection for colour, we also show that sexual selection

117 for bright-light vision and relatively weak selection for dim-light vision.

118 y network inference and facilitate candidate selection for experimentation, we developed an algorithm

119 We conclude that selection for high rate of biosynthesis implies a select

120 suggesting that our analysis mainly detects selection for proper folding of the TCR receptor protein

121 amination of other TCRBV families also shows selection for rearrangement within the V region of a num

122 d computational methods can guide antibiotic selection for TB.

123 We assessed the effect of selection for tracing using Kaplan-Meier estimates of re

124 This would reduce the strength of selection for traits that lead to success in direct cont

125 ative kin discrimination can be explained by selection for unrelated targets to invest more effort in

126 These results will be useful for vector selection for various applications.

127 Primary consumers are under strong selection from resource ('bottom-up') and consumer ('top

128 Our results show that male sexual selection gradients are consistently positive.

129 allele frequency suggests pathogen-mediated selection has occurred due to CWD.

130 To determine the effects that drift gas selection has on the information content of IM separatio

131 teral amygdala impede goal-directed response selection, implicating BDNF-expressing OFC projection ne

132 Finding a signature of purifying selection in a gene is usually interpreted as evidence f

133 ) with functional exogenous mitochondria and selection in a restrictive medium.

134 on site and, consequently, abnormal bud-site selection in daughter cells.

135 ication genes, as well as evidence of recent selection in flowering genes possibly associated with th

136 nstration of functional intrathymic negative selection in I-A(12%) mice, transfer of I-A(12%) CD25(-)

137 in every nonessential gene was subjected to selection in NHS.

138 an environments favors different traits than selection in rural environments and that these differenc

139 Here, we explore the role of natural selection in shaping the processes that underlie social

140 sts xenophilia can evolve through individual selection in social species whenever the benefits of bui

141 We present a new test for selection in the same class as Fay and Wu's H and discus

142 nters to explicitly define the mechanisms of selection in this complex evolutionary process.

143 We are the first to detect positive selection in this overlap region.

144 Taken together, our results suggest that selection in urban environments favors different traits

145 ortunities to observe the effects of natural selection in wild populations.

146 Neanderthals, and the ways in which natural selection, in its various guises, has shaped genome dive

147 The genes showing the strongest evidence of selection-including BRINP3, NOS2, and TBX5-are associate

148 ost reactive pathways, generating a reaction selection index (RSI) without need for separate work-up

149 We also found that selection intensity for all traits depended on pollinati

150 when considering variables related to sexual selection intensity, such as sexual dimorphism and repro

151 omit potential gains by integrating genetic selection into existing breeding programs.

152 Sexual selection is a fundamental evolutionary process but rema

153 G start codons in yeast mutants in which UUG selection is abnormally high.

154 APP processing, and the BACE1 cleavage site selection is critical for amyloidogenesis in AD pathogen

155 Reference region selection is important for proper amyloid PET analysis,

156 particular, our results suggest that sexual selection is likely to favour individual differences in

157 However, the genome-wide intensity of this selection is not exceptional compared with what M. gutta

158 contribution of apoptosis to GC biology and selection is not well defined.

159 Visual selection is thus non-normative and economically irratio

160 ency between allotypes, but the mechanism of selection is unknown.

161 lection for colour, we also show that sexual selection leads to greater expansion of the non-recombin

162 a colony's curvature at the frontier and its selection length scale.

163 Balancing selection maintains variation for evolution.

164 jor salt tolerance genes and marker assisted selection (MAS) can accelerate wheat breeding for this t

165 occur in nature, suggesting that fluctuating selection may be a more common and important process tha

166 Here, we suggest that environmental selection may be sufficient to suppress and stymy sexual

167 ic cancers and the optimal assay for patient selection may inform clinical trial design for immunothe

168 strategy, called PRES (Personalized REgimen Selection), may significantly increase response rates fo

169 quantification and interpretation of sexual selection measures, an insight that applies to any itero

170 ection procedure (Lasso-PL) and the analytic selection method (Lasso-AL) are fast and powerful altern

171 biomarker developed using a stepwise feature selection method could classify the legions with a sensi

172 We developed a filter-based feature selection method for temporal gene expression data based

173 s at least comparable to traditional feature-selection methods for prediction of MMP-2, -3, -7, -8, -

174 e over time in response to processes such as selection, migration, and drift.

175 alleles and the sex that experiences haploid selection most often (e.g., pollen beneficial alleles be

176 variants simply reflect the balance between selection, mutation, and drift.

177 As a source of genetic diversity and natural selection, mutations are beneficial for evolution.

178 rm plasm might be neither a direct target of selection nor causally linked to accelerated animal evol

179 By selection of 1 item from each domain, the 10-point SaFET

180 ricted cues critical for differentiation and selection of a functional, self-tolerant T cell repertoi

181 pithelial cells just before delamination and selection of a proneural cell fate in the early Drosophi

182 f molecular profiling to guide prognosis and selection of actionable therapeutic targets.

183 The selection of an appropriate Vt is an essential part of a

184 rations show good agreement, but reveal that selection of analytical window can impact which binding

185 nce genotyping is recommended to help in the selection of antiretroviral therapy and to prevent virol

186 The selection of appropriate protein immobilization strategi

187 and prognostic molecular biomarkers involve selection of assays, type of specimens to be tested, tim

188 protein is the key factor in thymic negative selection of autoreactive T cells by promoting the ectop

189 by the expansion, somatic hypermutation, and selection of B cell clones.

190 ity antibody responses depend on competitive selection of B cells carrying somatically mutated B-cell

191 The latter was overcome by selection of BCL-2 overexpressing cells under overnutrit

192 ple with focal epilepsy but requires careful selection of candidates.

193 Such an approach may find use in label-free selection of cells for a highly expressed molecular phen

194 Selection of central venous catheter insertion site in I

195 final drinking water microbial community via selection of community members and that the bacterial co

196 Selection of contacts for chronic stimulation was made b

197 ucible in vitro differentiation and positive selection of conventional human T cells from all sources

198 In this study, we demonstrated the selection of DNA aptamers with high affinity and specifi

199 spatiotemporal niches, and the evolutionary selection of donor L1s driving neuronal mosaicism.

200 Now, with the selection of Dr.

201 Although selection of GC B cells is triggered by antigen-dependen

202 species that were determined by the feature selection of GDBT were identified by tandem mass spectro

203 r origin of high affinity IgE and the clonal selection of high affinity memory B cells into the plasm

204 The positive selection of immature CD4(+)CD8(+) double-positive thymo

205 roach we developed quantitative motifs for a selection of kinases from each branch of the kinome, wit

206 By careful selection of LHGs, different types of amphiphiles (both

207 tric subgenome domestication for directional selection of long fibers.

208 A selection of metabolites, including time-sensitive metab

209 Recently, a selection of MOFs has been demonstrated to undergo melti

210 ypically develop resistance through stepwise selection of multiple drug-resistance mechanisms.

211 I have been blessed with the selection of my research topic: RNA biology.

212 ogists, guidance is provided for morphologic selection of neoplastic tissue, testing algorithms, scor

213 mework, which enables the identification and selection of new biomarkers of human exposure to drugs w

214 y and access with a track hub registry and a selection of new REST end points.

215 We hypothesize that positive selection of novel phosphorylation sites in the protein

216 Advances in the selection of optimal T cells, genetic engineering, and c

217 We then apply the XP-PCM method to a selection of other pericyclic reactions, including the p

218 The selection of oxide materials for catalyzing the oxygen e

219 Further work is needed to aid with the selection of patients most likely to benefit from stress

220 d regulation continues to focus on a limited selection of rather well-known long-chain PFASs, particu

221 In an innovative research enterprise, selection of results for further evaluation based on nul

222 We find that the optimal selection of sentinels depends on both the network's tem

223 th evolutionarily conserved genes suggesting selection of specific alleles of genes responsible for b

224 is mutation preceded and may have driven the selection of substitutions in H7 that modify H7 receptor

225 paired with a particular stimulus increases selection of that stimulus, and this effect was stimulus

226 or failure of a Trump presidency, based on a selection of the 17 Sustainable Development Goals that a

227 With an optimal selection of the AC physicochemical characteristics it w

228 ize or stiffness of the matrix influence the selection of the mechanism used by cells to propel thems

229 GNIFICANCE STATEMENT: Attention involves the selection of the most relevant information for different

230 The selection of the proper electrolyte, including solvents

231 hilin's phosphorylation state enforced track selection of the Rab27a/melanophilin/myosin Va transport

232 rimentally and computationally that a proper selection of the substitution scheme can enhance the syn

233 of these isolates were typed to CC398 and a selection of these (n = 38) were further characterised f

234 immune responses in the human host; forcing selection of viral variants that escape cellular and ant

235 d), only three showed evidence for purifying selection (omega </= 0.14).

236 ental aspects of their environment, creating selection on behaviours and other traits.

237 historical contingency alter the strength of selection on different genes.

238 ains unclear whether frugivores exert strong selection on fruit traits.

239 Maize G x E project to assess the effect of selection on G x E variation and characterize polymorphi

240 Here, we show that selection on photosynthetic traits within and across tax

241 after evolution of gentle behaviour, despite selection on standing variation.

242 We find that both the nature of selection on the influenza genome and the accessibility

243 acid properties provide evidence of positive selection on the ND2 and ND5 genes against a background

244 and Escherichia coli We compare patterns of selection operating on IGRs using two independent the pr

245 records) and a least absolute shrinkage and selection operator method.

246 Using the "Least absolute shrinkage and selection operator" (Lasso), we analyzed all metabolites

247 ot involved in CD8 single-positive thymocyte selection or ERK signaling.

248 ve tended to find negative effects of sexual selection, or no effect.

249 The eQTLs are predominantly under negative selection, particularly those affecting essential genes

250 First, in the seed selection phase, the proposed method utilizes the CUFID

251 ed excellent agreement with the data for all selection points using the same value of the conversion

252 g evolution N-glycosylation triggered a dual selection pressure on secretory pathway proteins: while

253 med that HPV-positive cancer cells are under selection pressure to continuously express the viral E6/

254 ulting redundancy of RITS may have eased the selection pressure, resulting in progressive loss or tru

255 nabling adaptive responding under this basic selection pressure.SIGNIFICANCE STATEMENT Among the most

256 This may result from the variety of selection pressures from herbivores, long distance gene

257 Our study demonstrates that the selection pressures of a 3(rd) generation cephalosporin

258 ework for understanding the origin of global selection pressures on proteins.

259 Atlantic salmon (Salmo salar) parents alter selection pressures on their offspring with important co

260 ates adaptation in response to the immediate selection pressures that a virus experiences in its curr

261 nfection-associated, short-term, within-host selection pressures.

262 esults suggest that the proposed permutation selection procedure (Lasso-PL) and the analytic selectio

263 ions and best practices to individualize the selection process, and the use of testosterone in men wi

264 es common to angiosperms during the breeding selection process.

265 ound effects on their hosts, driving natural selection, promoting speciation and determining species

266 of the most potent selective forces, sexual selection, remains curiously unexplored.

267 d tonic dopamine (DA) in action learning and selection, respectively.

268 from a 12-mer peptide library in successive selection rounds.

269 ondition, entropic factors, rather than spin-selection rules, are the source of the reduced Arrhenius

270 In the absence of antibiotic-mediated selection, sensitive bacteria are expected to displace t

271 sis can profoundly influence the response to selection, shaping the adaptive trajectories of natural

272 ys, which could be related to conformational selection, signaling amplification, and probe dependence

273 , for unbiased estimation and stable feature selection simultaneously.

274 identifies signals of repeated evolutionary selection, some of which may be linked to response to si

275 sed a parallel dense-module search and cross-selection strategy to identify an asthma-associated gene

276 During thymic selection, T cells bearing T cell receptors (TCRs) with

277 The variable selection techniques studied in this work include Marten

278 Unlike conventional feature selection techniques that select features based on their

279 formance is heavily dependent on the feature selection techniques, like the diagnosis of neurodegener

280 ry theory, exploring potential mechanisms of selection that maintain high linkage disequilibrium in M

281 sed on multivariable Cox models and stepwise selection, the 3 most discriminating variables were the

282 translation, which are maintained by strong selection, the average selection coefficient for most no

283 pleted sample displayed evidence of positive selection, the lambda genes in sIgkappa(+) cells accumul

284 ual conflict if it acts orthogonal to sexual selection, thereby placing limitations on the evolution

285 We show that negative selection thresholds chosen to reflect experimentally ob

286 ted 12 diverse molecular targets for Affimer selection to exemplify their use in common molecular and

287 ncy were positively correlated among whorls, selection to improve fitness through female (or male) fu

288 s of animal ecology from foraging to habitat selection to predator avoidance.

289 n which strong linkage limits the ability of selection to purge deleterious mutations.

290 mocytes must pass both positive and negative selections to become mature T cells.

291 matic hypermutation (SHM) and affinity-based selection toward antigen in activated germinal center (G

292 Here we present the Time Point Selection (TPS) method that solves this combinatorial pr

293 However, natural selection typically generates adaptation in response to

294 n this study can be used for marker assisted selection using haplotype blocks as a wheat breeding str

295 fferentiation due to past divergent climatic selection vs. plastic responses to ongoing climate chang

296 erforming functional prediction and stepwise selection, we identified two independent SNPs (i.e., WNT

297 e frame affects estimated measures of sexual selection, we recorded mating success and reproductive s

298 ature search and prospectively defined study selection, we sought systematic reviews, meta-analyses,

299 ug combinations with a mechanistic basis for selection, which suggests that combining AKT and WEE1 in

300 l challenge, which probably accounts for its selection within human populations but provides this adv