ライフサイエンスコーパス: selective action

1 MTSB-6 shows improvements in its selective action against noncancer prostate cells over m

2 hways has led to the discovery of drugs with selective action against specific PDE isoforms.

3 ates, especially as 11 and 12 express direct selective action against tumors expressing MDR.

4 ese data indicate that differences in tissue selective actions among benzothiophene and triarylethyle

5 t classes based on structure and may exhibit selective actions and carcinogenic potential based on di

6 D(2) and serotonin 5-HT(2A) receptors or 2) selective action at limbic cortical dopamine D(2)-like r

7 t at multiple cellular sites and then have a selective action at the nicotinic ACh receptor cation ch

8 For example, an agent with selective actions at the beta3-containing subunit of the

9 How such selective action can arise despite the existence of mass

10 ovide a theoretical basis for the relatively selective action certain antifolates may have against MT

11 etaarr2-biased D2R ligands that exert region-selective actions could provide a path to develop more e

12 been the identification of ligands with gene-selective actions, impacting disease outcomes through a

13 rus and both MVM strains showed highly tumor-selective actions in glioblastoma plus fibroblast cocult

14 al, and eukaryotic ribosomes account for the selective action of antibiotics.

15 number, indicating that this is a common and selective action of antidepressants.

16 forms of synaptic regulations appear to be a selective action of BDNF because intrinsic excitability,

17 n this report, the mechanistic basis for the selective action of Bz-423 is investigated.

18 nt and unexpected mechanism accounts for the selective action of chitinases and possibly other moltin

19 es may provide valuable new insight into the selective action of enzymes on damaged DNA.

20 These results suggest that the selective action of EPO on erythropoiesis is determined

21 wnregulation of ERalpha provides a basis for selective action of estradiol produced locally by autocr

22 ucocorticoid-dependent mechanism whereby the selective action of estradiol via ERbeta may be promoted

23 etter understand the molecular mechanisms of selective action of estrogen receptor ligands, we charac

24 ressor exclusively on self-surfaces and this selective action of FH is pivotal to self versus non-sel

25 st firing and motor deficits, confirming the selective action of flupenthixol on D5Rs.

26 The selective action of glutamine on fibroblast proliferatio

27 The selective action of HDAC inhibitors on HDAC-PP1 complexe

28 The mechanism of the tumor selective action of HDACi is unclear.

29 The selective action of MT-DADMe-ImmA on head and neck squam

30 lk between these two signal cascades and the selective action of p38 in migration appear to be import

31 ng enzymes including GSTs, but the basis for selective action of safeners between monocots and dicots

32 rgets for immunosuppressive therapy, but the selective action of Spns2 may present an advantage in th

33 This approach allows selective action of the CXCL12 neutraligands although th

34 dicted, these modifications altered the AChE-selective action of tolserine (5) to favor a lack of cho

35 and establish the framework for defining the selective action of two vessel-targeting drugs against n

36 ssible explanations for the tissue- and gene-selective actions of 2MD.

37 th drug-eluting stents may be due to the non-selective actions of antimitogenic drugs on endothelial

38 results define properties associated with AF-selective actions of class-I antiarrhythmic drugs and su

39 s binding to ER may potentially underlie the selective actions of different ER ligands in various cel

40 ne of these factors duplicate the potent and selective actions of GDNF in vivo.

41 Transcriptional repression is based on the selective actions of recruited corepressor complexes, in

42 d the induction of COX-2, which demonstrated selective actions of these two closely related bioactive

43 p38 MAPK is regulated by the coordinated and selective actions of three different protein kinases in

44 At 50 ng, 8-OH-DPAT had a selective action on anxiety, while at 200 ng there was a

45 ese data indicate that NO inactivates TPH by selective action on critical SH groups (i.e., cysteine r

46 tumor development in experimental animals by selective action on specific molecular targets, such as

47 xcitotoxic cell death, in agreement with its selective action on the corresponding recombinant recept

48 Given its selective action on the omega1 subtype of the gamma-amin

49 This selective action on the retractor phase results from two

50 the sinusoidal transporter confirming their selective action on this transporter.

51 ient to cause PD, but the mechanism of their selective action on vulnerable DA SN neurons is unknown.

52 ese studies demonstrate that urocortin 2 has selective actions on a subset of DR serotonergic neurons

53 In conclusion, exogenous ANXA1 displayed selective actions on human PMN.

54 They have selective actions on peripheral blood cells, in that pre

55 M(1) to specific signaling pathways leads to selective actions on some but not all M(1)-mediated resp

56 ss of pharmacological agents with potent and selective actions on the Ca2+ receptor.

57 This selective action suggests that tricin could be considere

58 and further demonstrate the range of agonist-selective actions that are possible through G-protein-co

59 lent among current antineoplastics and whose selective action toward breast cancer is tailored to the