ライフサイエンスコーパス: selective estrogen receptor modulator

1 gs to a class of drugs recently described as selective estrogen receptor modulators.

2 PPARgamma and retinoid X receptor alpha with selective estrogen receptor modulators.

3 es are classified as both phytoestrogens and selective estrogen receptor modulators.

4 genic/estrogenic actions, characteristics of selective estrogen receptor modulators.

5 ed estrogenic and antiestrogenic activity of selective estrogen receptor modulators.

6 breast cancer are associated with the use of selective estrogen receptor modulators.

7 A novel SERM (selective estrogen receptor modulators), 1-(R), a chrome

8 onal activity of ERalpha can be regulated by selective estrogen receptor modulators, a new class of d

9 photoreceptor degeneration that tamoxifen, a selective estrogen receptor modulator and a drug previou

10 Both selective estrogen receptor modulators and aromatase inh

11 This relationship does not extend to selective estrogen receptor modulators and pure antagoni

12 method for the determination of idoxifene, a selective estrogen receptor modulator, and its pyrrolidi

13 de the mild androgen dehydroepiandrosterone, selective estrogen receptor modulators, and the prolacti

14 Tamoxifen, a selective estrogen receptor modulator approved for the t

15 Selective estrogen receptor modulators are an emerging c

16 The preliminary data on selective estrogen receptor modulators are not overly pr

17 We show that the selective estrogen receptor modulator arzoxifene (Arz) a

18 he altered (i.e., agonistic) pharmacology of selective estrogen receptor modulator drugs in this path

19 like action at activating function 2b of the selective estrogen receptor modulator ERalpha complex.

20 strates a novel allosteric mechanism for the selective estrogen receptor modulator ERalpha complex.

21 in regulating the estrogen-like activity of selective estrogen receptor modulator-ERalpha complexes.

22 Tamoxifen (TX), a selective estrogen receptor modulator, exerts antagonist

23 Heart (RUTH) trial showed that raloxifene, a selective estrogen receptor modulator, had no overall ef

24 Tamoxifen, a selective estrogen receptor modulator, has antifibrotic

25 at mechanistic differences between different selective estrogen receptor modulators have been transla

26 Denosumab and toremifene (a selective estrogen receptor modulator) have each been sh

27 benefits in the brain, including the use of selective estrogen receptor modulators, high soy diets,

28 Raloxifene, a selective estrogen receptor modulator, improves cardiova

29 a and ERbeta and differentially regulated by selective estrogen receptor modulators in a cell line-de

30 micked by the membrane impermeant E2-BSA and selective estrogen receptor modulators, including a new

31 Clomiphene citrate, a selective estrogen receptor modulator, increases estradi

32 Selective estrogen receptor modulator is a proven agent

33 contrast, raloxifene (Ral), which is also a selective estrogen receptor modulator, is a complete ant

34 4-Hydroxytamoxifen (4-OHT), a selective estrogen receptor modulator, is an agonist at

35 Raloxifene, a selective estrogen receptor modulator, is currently used

36 Tamoxifen, a selective estrogen receptor modulator, is widely used in

37 dy designed to test the ability of the novel selective estrogen receptor modulator lasofoxifene (LAS)

38 Whether raloxifene, a selective estrogen-receptor modulator, might have simila

39 Raloxifene hydrochloride is a selective estrogen receptor modulator (mixed estrogen ag

40 te the therapeutic potential of tamoxifen, a selective estrogen receptor modulator, on estrogen-induc

41 dy was to examine the effects of LY117018, a selective estrogen receptor modulator, on peripheral ner

42 The effect of raloxifene, a selective estrogen-receptor modulator, on coronary heart

43 We evaluated the effects of toremifene, a selective estrogen-receptor modulator, on fasting serum

44 es of AIs in combination with more effective selective estrogen receptor modulators or selective rece

45 Raloxifene hydrochloride, a selective estrogen receptor modulator, prevents bone los

46 , our laboratory reported that raloxifene, a selective estrogen receptor modulator, promoted regressi

47 Administration of tamoxifen, a selective estrogen-receptor modulator, restored fertilit

48 Tamoxifen, a member of the selective estrogen receptor modulator (SERM) family, is

49 A selective estrogen receptor modulator (SERM) for the pot

50 The design of a novel selective estrogen receptor modulator (SERM) for the pot

51 ith raloxifene, tamoxifen, and nonusers of a selective estrogen receptor modulator (SERM) in the gene

52 triphenylethylene bisphenol analogues of the selective estrogen receptor modulator (SERM) tamoxifen w

53 An efficient asymmetric synthesis of a selective estrogen receptor modulator (SERM) that has a

54 Bazedoxifene (BZA) is a third-generation selective estrogen receptor modulator (SERM) that has be

55 2-(4-methoxyphenyl)]be nzo[b]thiophene) is a selective estrogen receptor modulator (SERM) that is a p

56 sterone) replacement therapy (CRT) (n = 16), selective estrogen receptor modulator (SERM) therapy (n

57 The 2-arylbenzothiophene raloxifene, 1, is a selective estrogen receptor modulator (SERM) which is cu

58 Trioxifene (LY133314) is a selective estrogen receptor modulator (SERM) with compet

59 Tamoxifen, a selective estrogen receptor modulator (SERM), represents

60 ivities of SP500263, a novel next-generation selective estrogen receptor modulator (SERM), tamoxifen,

61 en, a breast cancer therapeutic, is a tissue-selective estrogen receptor modulator (SERM), which acts

62 353381.HCl-a novel, potent, third-generation selective estrogen receptor modulator (SERM)-because thi

63 Idoxifene (ID) is a tissue-selective estrogen receptor modulator (SERM).

64 icating that 27HC functions as an endogenous selective estrogen receptor modulator (SERM).

65 We tested whether the therapeutic selective estrogen receptor modulators (SERM), raloxifen

66 y agonists, but surprisingly antagonists and selective estrogen receptor modulators (SERMs) activated

67 e most significant recent findings regarding selective estrogen receptor modulators (SERMs) and selec

68 d with adjuvant endocrine therapy, including selective estrogen receptor modulators (SERMs) and/or ar

69 Selective Estrogen Receptor Modulators (SERMs) are a new

70 Selective estrogen receptor modulators (SERMs) demonstra

71 scriptional activity of natural estrogens or selective estrogen receptor modulators (SERMs) has not b

72 Selective estrogen receptor modulators (SERMs) have been

73 Traditional approaches to discovery of selective estrogen receptor modulators (SERMs) have reli

74 Tamoxifen and its analogues act as selective estrogen receptor modulators (SERMs) in women,

75 Estrogens and selective estrogen receptor modulators (SERMs) interact

76 of estrogenic and antiestrogenic effects of selective estrogen receptor modulators (SERMs) is though

77 Selective estrogen receptor modulators (SERMs) mimic est

78 Very little is known about the impact of selective estrogen receptor modulators (SERMs) on the br

79 Selective estrogen receptor modulators (SERMs) partially

80 Selective estrogen receptor modulators (SERMs) show diff

81 s of estrogen's action and determine whether selective estrogen receptor modulators (SERMs) such as t

82 Selective estrogen receptor modulators (SERMs) such as t

83 section of the mechanism(s) of action of the Selective Estrogen Receptor Modulators (SERMs) tamoxifen

84 resentative of a class of compounds known as selective estrogen receptor modulators (SERMs) that poss

85 Selective estrogen receptor modulators (SERMs) that supp

86 The interaction of selective estrogen receptor modulators (SERMs) with lipi

87 bone in the ovariectomized rat by estrogen, selective estrogen receptor modulators (SERMs), and bisp

88 art of a program aimed at the development of selective estrogen receptor modulators (SERMs), novel ch

89 Several FDA-approved drugs, including selective estrogen receptor modulators (SERMs), possess

90 Current interventions include selective estrogen receptor modulators (SERMs), prophyla

91 Selective estrogen receptor modulators (SERMs), such as

92 gene, and they are more appropriately called selective estrogen receptor modulators (SERMs).

93 tissue-selective pharmacology of an array of selective estrogen receptor modulators (SERMs).

94 been to create dual aromatase inhibitor (AI)/selective estrogen receptor modulators (SERMs).

95 it estrogen action at the estrogen receptor (selective estrogen receptor modulators (SERMs]); or (2)

96 romatin is a key determinant of estrogen and selective estrogen receptor modulator signaling in the E

97 hydroxy-phenyl)-propionitrile (DPN), and the selective estrogen receptor modulator tamoxifen (Tam), i

98 ells, and promoted hormone resistance to the selective estrogen receptor modulator tamoxifen and sele

99 Resistance to the selective estrogen receptor modulator tamoxifen and to a

100 The selective estrogen receptor modulator tamoxifen has been

101 The selective estrogen receptor modulator tamoxifen is used

102 The selective estrogen receptor modulator tamoxifen was also

103 only known CNS-permeant PKC inhibitor is the selective estrogen receptor modulator tamoxifen.

104 the risk for breast cancer-specifically, the selective estrogen receptor modulators tamoxifen and ral

105 Hormone therapy with the selective estrogen-receptor modulator tamoxifen provides

106 ed the effects on uterine development of the selective estrogen receptor modulators, tamoxifen, torem

107 Raloxifene hydrochloride is a selective estrogen receptor modulator that has antiestro

108 Raloxifene is a selective estrogen receptor modulator that has estrogen-

109 Tamoxifen (TMX) is a selective estrogen receptor modulator that is used as an

110 Phytoestrogens may act as natural selective estrogen receptor modulators that elicit disti

111 Tamoxifen and raloxifene are selective estrogen receptor modulators that have been sh

112 Arzoxifene and TSE-424 are investigational selective estrogen receptor modulators that have been sh

113 In addition, tamoxifen and raloxifene, two selective estrogen receptor modulators that have protect

114 Four of them were known selective estrogen receptor modulators that were never r

115 aromatase inhibitors, fenretinide, or other selective estrogen receptor modulators to lower BC risk

116 hly facilitate the design of tissue-specific selective estrogen receptor modulators to treat breast c

117 , whereas the ERbeta-mediated agonism of all selective estrogen receptor modulators was present.

118 The 2-arylbenzothiophene raloxifene, 1, is a selective estrogen receptor modulator which is currently

119 Tamoxifen (TAM) is a selective estrogen receptor modulator widely used in the

120 d use of well defined forms of estrogens and selective estrogen receptor modulators will continue to

121 pha actions may provide means to develop new selective estrogen receptor modulators with improved pro

122 Isoflavones are naturally occurring selective estrogen receptor modulators, with potential b