ライフサイエンスコーパス: selectively block

1 -promoting cytokine if the Stat1 function is selectively blocked.

2 nd reservoirs--transmission to the cocoon is selectively blocked.

3 The tumor cell uptake can be selectively blocked.

4 in long lasting nonkilling cell couples was selectively blocked.

5 A new approach for the synthesis of selectively blocked 3-amino-3-deoxyaldopentoses is prese

6 ithin a given cell can lead to strategies to selectively block a function.

7 early limited by the lack of inhibitors that selectively block a single kinase implicated in neoplast

8 ate (Gleevec); Novartis], which potently and selectively blocks Abl kinase activity, implicate AFKs i

9 bitory kappa B (IkappaB) kinase (dnIkk) that selectively blocked activation of NF-kappaB caused loss

10 injections of pharmacologic agents known to selectively block activity of particular cells and circu

11 Co-administration/pretreatment of naloxone selectively blocked activity in pulvinar, pons and poste

12 tics of both analgesia and algesia; naloxone selectively blocks activity in areas associated with alg

13 d thus we used antisense oligonucleotides to selectively block AH VIP production in male and female w

14 entrations of picrotoxin (</= 30 muM), which selectively blocked alpha homomeric GlyRs.

15 used a polyamine agent, philanthotoxin, that selectively blocks AMPA receptors lacking GluR2 subunits

16 To identify drug targets to selectively block aromatase and estrogen production in b

17 is a bona fide target whose inhibition would selectively block aromatase expression in breast, while

18 ow dose of amiloride used in our experiments selectively blocked ASICs, whereas the high dose blocked

19 c T lymphocyte antigen 4 (CTLA-4) engagement selectively blocked augmentation of gene regulations by

20 tigen-specific immunotherapy, an approach to selectively block autoimmune diabetes, generally decline

21 roscopy suggested that amelogenin assemblies selectively blocked b-axial development, resulting in th

22 e have designed two CD28 peptide mimics that selectively block B7:CD28 interactions.

23 ore, we developed a functional CD28 mimic to selectively block B7:CD28 interactions.

24 TLA4-Ig or mutant CTLA4-Ig (Y100F-Ig), which selectively blocks B7.1.

25 Thus, NCoRi selectively blocked basal transcription of several thyro

26 activation of NF-kappaB in FM B cells, which selectively blocked BCR stimulation of cell survival and

27 IgG) that mimics the BDNF receptor, TrkB, to selectively block BDNF in the hippocampus during 3 days

28 membrane-proximal C terminus dileucine motif selectively blocked beta(2)-AR interaction with Rab8, wh

29 tions in regulating CD8(+) T-cell responses, selectively blocking beta-catenin with a pharmacological

30 ide and benzisothiazolone derivatives, which selectively block binding of the estrogen receptor to it

31 Hydrophobic substitutions for Arg343 selectively blocked binding of a monoclonal antibody (Hy

32 vator p300, whereas the helical domain alone selectively blocks binding to p300.

33 inculin, and a point mutation in this region selectively blocks binding to the Arp2/3 complex.

34 Hu proteins, we have shown that Hu proteins selectively block both cleavage and poly(A) addition at

35 In human platelet-rich plasma (PRP), RvE1 selectively blocked both ADP-stimulated and thromboxane

36 en hENT1 activity on the plasma membrane was selectively blocked by 10 nm nitrobenzylthioinosine.

37 I(K,f) was selectively blocked by 30 nm IbTx but was unaffected by

38 omain mediates these actions of Homer and is selectively blocked by a peptide that mimics the Homer l

39 Zap70 mutant whose catalytic activity can be selectively blocked by a small-molecule inhibitor.

40 in acutely isolated slice preparations were selectively blocked by antagonists of Kv1.3, illustratin

41 eceptor- stimulated Erk phosphorylation were selectively blocked by cellular expression of two peptid

42 ate (cGMP) levels, with all of these effects selectively blocked by CK2 inhibitors.

43 is permeable to K(+) and Na(+) ions, and is selectively blocked by Cs(+) and ZD7288.

44 ated by increased firing frequencies, and is selectively blocked by cyclosporin A and FK506.

45 ed by nicotine, desensitized rapidly and was selectively blocked by dihydro-beta-erythroidine, thus e

46 on progesterone treatment, and this was also selectively blocked by dynasore.

47 stimulate feeding which is respectively and selectively blocked by GABA(A) (bicuculline) and GABA(B)

48 anosine incorporation into nucleic acids was selectively blocked by Imm-H with no effect on guanine,

49 formation, and oocyte fate determination are selectively blocked by low levels of microtubule-depende

50 ponse to beryllium was nearly completely and selectively blocked by mAb to HLA-DP.

51 C proliferation and ERK phosphorylation were selectively blocked by neutralization of AREG.

52 al tegmental area (VTA); these responses are selectively blocked by pretreatment with corresponding G

53 The slow component of inhibition was selectively blocked by regulator of G protein signalling

54 showed that these epileptogenic effects are selectively blocked by the alpha-amino-3-hydoxy-5-methyl

55 nt potentiation through a mechanism that was selectively blocked by the BDNF scavenger TrkB-Fc, the T

56 When V3-mediated neurotransmission is selectively blocked by the expression of the tetanus tox

57 The fast component of inhibition was selectively blocked by the Gbetagamma-binding region of

58 more efficiently, and this was partially but selectively blocked by the general SR inhibitor, poly(I)

59 -1 promoter that was activated by MEKK-1 and selectively blocked by the MEK1,2 inhibitor PD98059.

60 ces Xenopus laevis oocyte maturation that is selectively blocked by two ras-p21 peptides, 35-47, also

61 contrast, when the cervical generators were selectively blocked, C8 DR stimulation was unable to act

62 Consistent with this, selectively blocking calcium-permeable AMPARs with Naspm

63 Micromolar Ni(2+), an agent that selectively blocks CaV3.2 but not CaV1.2/CaV3.1, was fir

64 glycosphingolipids (GSLs; a subgroup of SLs) selectively blocked caveolar endocytosis and decreased c

65 clinical deployment, and strategies aimed to selectively block CD28 without interrupting CTLA4/B7 int

66 tides with optimum PPII helical content that selectively block CD80-receptor interactions.

67 n LFA-1 and was prevented by antibodies that selectively block cell adhesion mediated by ICAM-1.

68 ion of Cdc34 protein levels in early mitosis selectively blocked centromere protein E (CENP-E), a mit

69 B cells 15 h after LPS plus IL-4 stimulation selectively blocked Cepsilon GLT expression and IgE secr

70 Furthermore, selectively blocking CICR with ryanodine slowed the Ca2+

71 act directly on purified gamma-secretase to selectively block cleavage of APP- but not Notch-based s

72 nd cycloheximide (CHX)-that are predicted to selectively block constitutive secretion on the release

73 Hence, ARM1 selectively blocks conversion of LTA4 into LTB4, althoug

74 N(2)O selectively blocked currents arising from the Ca(v)3.2 b

75 Cx43 gap junctions, indicating that spermine selectively blocks Cx40 gap junctions.

76 The antimalarial drug mefloquine, which selectively blocks Cx50 and not Cx46 GJs, shows the same

77 pharmacologic characterization of nanobodies selectively blocking CXCR2, the most promiscuous of all

78 As with ERK activation, stromal contact selectively blocked delayed but not early Rap1 activatio

79 vel 19S regulatory particle inhibitor b-AP15 selectively blocks deubiquitylating activity of USP14 an

80 controls mesenchymal lineage progression by selectively blocking differentiation of osteoblasts and

81 Antisense oligodeoxynucleotides can selectively block disease-causing genes, and cancer gene

82 lation of N- and M-type currents but did not selectively block distinct G-protein pathways.

83 T), we were able to rapidly, reversibly, and selectively block dopamine D1 and D2 receptors (D1R and

84 with upstream deficiencies, suggesting that selectively blocking downstream targets may result in a

85 Here, we selectively block either postsynaptic firing in individu

86 ts alone and in complex with antibodies that selectively block either semaphorin or vascular endothel

87 defect at different interneuron subtypes, we selectively blocked either N-type or P/Q-type Ca(2+) cha

88 a history of dependence, and CRF antagonists selectively block emotionality, excessive alcohol drinki

89 identify two small-molecule inhibitors that selectively block endosome-to-Golgi retrieval of ricin a

90 negative reagents, it may now be possible to selectively block events postulated to be dependent on p

91 Low-dose NTX selectively blocks excitatory opioid receptors at their

92 the isolated variable domain of PKC-epsilon selectively blocked exogenous activation of the megakary

93 work indicated that yeast Srs2 DNA helicase selectively blocks expansions in vivo.

94 e also pharmacologically distinct, with AlF4 selectively blocking export of transferrin receptor from

95 l interfering RNAs (siRNAs) can potently and selectively block expression of mutant K6a.

96 inical setting, RNA interference was used to selectively block expression of specific isoforms of Ras

97 Accordingly, SARI selectively blocks expression of the transformed state i

98 r the Smc5/6 complex as a restriction factor selectively blocking extrachromosomal DNA transcription.

99 ools demonstrated that they were all able to selectively block F-LMP1-induced NFkappaB activity that

100 development by stimulating cell survival by selectively blocking Fas-mediated apoptosis.

101 C-terminal FGF23(180-251) competitively and selectively blocked FGF23 action without disrupting PTH

102 These results indicate that INA selectively blocks fusion of the virus with the target c

103 Pertussis toxin, which selectively blocks G(i/o) signaling, also had no effect.

104 C152S mutant in cells or providing a drug to selectively block GAPDH S-nitrosylation both made heme i

105 The drug CGP3466B, which potently and selectively blocks GAPDH nitrosylation and GAPDH-Siah bi

106 el small molecule Gbetagamma inhibitors that selectively block Gbetagamma-binding interactions, inclu

107 Rather, 4-methylumbelliferone directly and selectively blocked gene products associated with the pr

108 This was accomplished by selectively blocking group I or II receptors while unila

109 introduction of a bulkier valine side chain selectively blocked GTP binding by steric occlusion of t

110 t virus (AAV-HDAC3(Y298H)-v5), we found that selectively blocking HDAC3 deacetylase activity in eithe

111 These compounds establish the feasibility of selectively blocking hdm2-mediated ubiquitination of p53

112 w that the antiarrhythmic drug E-4031, which selectively blocks HERG channels, also corrects defectiv

113 udy suggest that the DRBP76:NF45 heterodimer selectively blocks HRV2 IRES-driven translation initiati

114 ve renewed hope for developing strategies to selectively block hyperactive RAS function.

115 Hence, preproenkephalin cDNA delivery selectively blocked hyperalgesia without disrupting base

116 markably low doses of CTX-B (10 ng/kg, s.c.) selectively blocks hyperalgesic effects elicited by morp

117 ata show that inhibiting Dectin-2 expression selectively blocked Hyphae-induced NF-kappaB, whereas in

118 e kinase Akt, a downstream effector of PI3K, selectively blocked IFN-beta-mediated induction of the b

119 of PI3-kinase activity by the drug LY294002 selectively blocked IGF- but not PDGF-mediated muscle ce

120 and tetrazoles were synthesized and found to selectively block IKCa1.

121 Selectively blocking IKCa1 channels with clotrimazole or

122 n primary Mphi, using short interfering RNA, selectively blocked IL-12 production and normalized the

123 We recently reported that tyrphostin AG-490 selectively blocked IL-2 activation of Jak3/Stat5 and gr

124 When heme biosynthesis is selectively blocked in hem1Delta mutant cells, the heme

125 Temperature-sensitive aep3 mutants are selectively blocked in incorporating [(35)S]methionine i

126 When heme biosynthesis is selectively blocked in mutated S. pombe cells, their abi

127 ant cultures, we show that bud initiation is selectively blocked in the prospective respiratory regio

128 -catenin signaling by dominant negative Tcf4 selectively blocked in vitro transformation by Gli1.

129 Sterols selectively block incorporation of SCAP into these vesic

130 ally, we confirmed that the d-AP-5 infusions selectively blocked induction of long-term potentiation,

131 encodes a saturable restriction factor that selectively blocks infection by N-tropic or B-tropic mur

132 hat bind to G protein betagamma subunits and selectively block interactions between betagamma subunit

133 lated with IL-13 in the presence of Abs that selectively block interactions of IL-13 with IL-13Ralpha

134 Xestospongin C (XeC) was shown to selectively block IP(3)-induced Ca(2+) release and IP(3)

135 Jip1 gene (Thr(103) replaced with Ala) that selectively blocks JIP1-mediated JNK activation.

136 2+) concentrations caused channel occlusion, selectively blocking K(+) fluxes towards the cytoplasm.

137 esic assays; however, gene knockout of JNK 1 selectively blocked kappa-receptor inactivation, whereas

138 Concanavalin A (Con A), which selectively blocks KAR desensitization, markedly increas

139 nyl)bis(azanediyl )) diethaneamine.2HCl] (8) selectively blocked Kv1.1 channels (IC50 approximately 1

140 Anti-Kv1.2 antibody selectively blocked Kv1.2 current expressed in the Xenop

141 le of presynaptic Kv1 channels in the rat by selectively blocking Kv1.1 and Kv1.2 containing channels

142 n showed that low concentrations of A-803467 selectively block "late" sodium current and shorten acti

143 tumor glucocorticoid activity, which in turn selectively blocks local COX-2 activity.

144 mouse embryonic fibroblasts and macrophages selectively blocks LPS-induced production of the pro-inf

145 In TG mice whose endothelial NF-kappaB was selectively blocked, LPS caused significantly less hypot

146 (peptide 5b) and (168)P-I(185) (peptide 6a), selectively blocked mAb7 binding to soluble CD9 and to C

147 Furthermore, erlotinib selectively blocked mammalian target of rapamycin signal

148 itors, orthovanadate and phenylarsine oxide, selectively block mGluR-LTD induced by application of th

149 Disruption of mGluR-Homer interactions selectively blocks mGluR activation of the phosphoinosit

150 Here, we found that selectively blocking mGluR5 significantly reduced the ba

151 Selectively blocking mitogen-activated protein kinase (M

152 ptor inactivation, whereas deletion of JNK 2 selectively blocked MOR inactivation.

153 We examined infarct volume after selectively blocking muscarinic M1 receptors with dicycl

154 tylcholinergic influence over D1R-neurons by selectively blocking muscarinic M4 receptors in the NAc-

155 After selectively blocking N-, Q-, L- and T-type channels, low

156 t blocks all sulfation or with an siRNA that selectively blocks N-sulfation significantly reduced erb

157 Ziconotide (formerly SNX-111) selectively blocks N-type voltage-sensitive calcium chan

158 We suggest the ideal myotonia therapy would selectively block NaPIC and spare the transient Na(+) cu

159 We used TTX and mu-conotoxin GIIIB to selectively block Nav1.4 in SD muscle and found that the

160 ntified mutations on the capsid surface that selectively block NC envelopment without affecting NC ma

161 TTX at 100 nm, which selectively blocks neuronal isoforms of Na+ channels, pr

162 Drugs that selectively block nitric oxide synthase (NOS) 2 enzyme a

163 Finally, Con G selectively blocked NMDA receptors containing the NR2B s

164 mbinant monoclonal anti-AQP4 antibodies that selectively block NMO-IgG binding to AQP4.

165 at YopJ functions as a "MAP kinase toxin" to selectively block nuclear responses that are triggered b

166 lls from our patient and PEL cell lines, AZT selectively blocked nuclear entry of the NF-kappaB heter

167 echanistic studies showed that sulfasalazine selectively blocks nuclear factor-kappaB-dependent gene

168 n cells with stratified dendrites, this drug selectively blocks On responses.

169 More recent strategies aimed at selectively blocking one of the key factors upstream rat

170 on, as established using a novel approach to selectively block only the sustained actin dynamics.

171 line food intake, whereas intra-BLA muscimol selectively blocked only DAMGO-induced food intake, leav

172 y reconstituting type I NKT cells as well as selectively blocking or activating type II NKT cells wit

173 limited, largely because of difficulties in selectively blocking other inhibitory neural pathways.

174 develop a new class of Notch inhibitors that selectively block outcomes that depend on Notch dimeriza

175 Based on our results, selectively blocking p38 activation with the SB202190 in

176 n a porcine model of bacteremic shock and b) selectively block PAF, thromboxane A2, prostacyclin, and

177 of TF signaling, antibody inhibition of EPCR selectively blocked PAR activation by the ternary TF-FVI

178 Finally, we find cathepsin inhibitors selectively block particle-induced NLRP3 activation, ind

179 smic face of a G-protein-coupled receptor to selectively block pathologic signaling while preserving

180 ents suggest a potential therapeutic role of selectively blocking PD-L1 in the recipient.

181 P/ABP and PICK1) and the phospho form (which selectively blocks PICK1) attenuated LTD induction by gl

182 ution containing 10 microm Ruthenium Red (to selectively block plasma membrane-localized receptors) a

183 Manipulations that selectively block post-Golgi trafficking halt dendrite g

184 These results show that selectively blocking presynaptic A2A receptors could pro

185 Pertussis toxin, a G(i/o) inhibitor, selectively blocked priming by C3a but had no effect on

186 tanding of these issues may point to ways of selectively blocking pro-death signalling in neurologica

187 -circuiting mechanism wherein the LRR domain selectively blocks productive aminolysis, but not the no

188 ografts demonstrated that inhibition of CHK1 selectively blocked proliferation of cells and tumors ex

189 pendent kinases (CDK) and Aurora kinases and selectively blocked proliferation of tumor cells of vari

190 ive small molecule ERalpha biomodulator that selectively blocks proliferation of drug-resistant ERalp

191 idues 119-136 of hamster PrP (Ha119-136) can selectively block PrP-res formation in cell-free systems

192 Inhibition of CaMKII selectively blocked recycling and caused intracellular a

193 lds a dominant-negative PACS-1 molecule that selectively blocks retrieval of PACS-1-regulated cargo m

194 Moreover, we generated anti-LRP4 antibodies selectively blocking sclerostin facilitator function whi

195 w-dose naltrexone or nor-binaltorphimine may selectively block signaling by endogenous GM1-sensitized

196 ken together, these data indicate that SOCS3 selectively blocks signaling by IL-6, thereby preventing

197 ted in non-neuronal cells, and that RGS2 can selectively block slow muscarinic inhibition while leavi

198 Together these results suggest that RGS2 selectively blocked slow inhibition by functioning as an

199 rupted Gapds expression by gene targeting to selectively block sperm glycolysis and assess its relati

200 tering common dynamic behaviors derived from selectively blocked splicing reactions, SiMCAn was able

201 The ability of RGS2 and PLCbeta1ct to selectively block stimulation indicates these proteins f

202 ing of the antibody had a functional effect, selectively blocking store-operated Ca(2+) channel activ

203 -1460, an inhibitor of GluA2-lacking AMPARs, selectively blocked synaptic excitation of FSIs but not

204 rly endosomal sorting in hippocampal neurons selectively blocks synaptic clustering of PSD95beta but

205 To selectively block T reg cell function in the skin, we re

206 for organ-transplant recipients are used to selectively block T-cell activity without global immunos

207 STAT5 signaling in activated CD4(+) T cells selectively blocked T(FH) cell differentiation and GCs,

208 These data indicate that N(2)O selectively blocks T-type but not HVA Ca(2+) currents in

209 Mibefradil, a new calcium antagonist that selectively blocks T-type calcium channels, has been sho

210 nstrate that inhibiting PKC activity in vivo selectively blocks tanning and reduces basal pigmentatio

211 By reconstructing or selectively blocking TCR-stimulated signaling pathways,

212 affect leukocyte adhesion or locomotion but selectively blocks TEM, suggesting a role for upward arr

213 SE differentiation can be enhanced by selectively blocking TGFbeta-RI signaling.

214 This compound selectively blocked Th17 differentiation, significantly

215 ntial for the design of molecules that might selectively block the acyl-CoA binding site.

216 Specific antagonists that selectively block the alpha9alpha10 channel could be val

217 trum antiprotozoal and antifungal drugs that selectively block the capping of pathogen-encoded mRNAs.

218 therapeutic applications for molecules that selectively block the endogenous generation of fucosylat

219 Lin28A and Lin28B selectively block the expression of let-7 microRNAs and

220 y of 18-MC might be related to an ability to selectively block the expression of sensitized extracell

221 By using catechol to selectively block the fast current, we completely occlud

222 applied at concentrations and durations that selectively block the hyperpolarization-activated, catio

223 Thus, either S-EITU does not selectively block the inducible nitric oxide synthase in

224 HCV infection, we showed that the compounds selectively block the initiation of replication of incom

225 tively slow binding antagonist, was found to selectively block the late signaling of the receptor, su

226 Amiloride was the first organic blocker to selectively block the native T-type calcium channel, but

227 ia a retrovirus-mediated gene transfer could selectively block the nuclear translocation of endogenou

228 ization experiments reveal that the peptides selectively block the nucleocytoplasmic shuttling of the

229 ion of apamin and charybdotoxin (CTX), which selectively block the small and large calcium-activated

230 By applying inhibitors to selectively block the ubiquitin proteasome system (UPS)

231 of the RhoA-noninteracting PLD1 mutant I870R selectively blocked the A3 agonist (Cl-IBMECA, 10 nM)-in

232 t alter AQP4 activity, whereas bacopaside II selectively blocked the AQP1 water channel (IC50 18 muM)

233 munoprecipitation assay indicated that Eri-B selectively blocked the binding between NF-kappaB and th

234 yl)-1H-imidazole (i.c.v.)] and found that it selectively blocked the conditioned place aversion cause

235 endritic MAP1B increase by both pathways, it selectively blocked the DHPG- and not the NMDA-induced A

236 pEPSC amplitude in both control and cKO, but selectively blocked the enhancement of PTP in cKO, witho

237 We have selectively blocked the expression of LAMP-2A in mouse f

238 al injections of the GABAA agonist muscimol, selectively blocked the expression of SFiA while having

239 gene encoding the transcription factor T-bet selectively blocked the formation and antigen-specific r

240 trahydroisoquinoline-6,7-diol hydrochloride] selectively blocked the growth of C6 glioma leaving norm

241 On gene expression analysis, LY294002 selectively blocked the induction of a subset of 14 LPS/

242 The drug orteronel selectively blocked the lyase reaction of P450 17A1 but

243 recordings showed that linopirdine and XE991 selectively blocked the M current at neuroprotective con

244 We found that the D1 antagonist SCH23390 selectively blocked the maintenance but not the inductio

245 inical experiments demonstrated that PLX4032 selectively blocked the RAF/MEK/ERK pathway in BRAF muta

246 ptor antagonists xestospongin C and caffeine selectively blocked the second phase, but not the initia

247 (1)/S transition phase of the cell cycle and selectively blocked the serum-stimulated expression of c

248 Application of curare (d-tubocurarine) selectively blocked the Si3 synapses in both species.

249 otein WASP; inhibition of podosome formation selectively blocked the transcellular route of diapedesi

250 hat vaccine-elicited neutralizing antibodies selectively blocked the transmission of more sensitive c

251 igase activity, inhibits immune responses by selectively blocking the binding of NF-kappaB and STAT1

252 th this, enhancing S408/9 phosphorylation or selectively blocking the binding of the beta3 subunit to

253 mechanism underlying losartan's benefits by selectively blocking the effects of angiotensin IV (AngI

254 -paclitaxel in ABCB1 overexpressing cells by selectively blocking the efflux function of ABCB1, but n

255 auses significant defects in skeletogenesis, selectively blocking the elongation of skeletal rods tha

256 We tested the possibility of selectively blocking the excitability of primary sensory

257 arly-onset hyperphagia and severe obesity by selectively blocking the expression of the proopiomelano

258 mitochondrial JNK signaling is inhibited by selectively blocking the interaction between JNK and Sab

259 ism: they act at post-translational level by selectively blocking the maturation of the viral hemaggl

260 However, strophanthidin, which selectively blocks the alpha1 isoform, was more effectiv

261 ibition of the alpha(4)-paxillin interaction selectively blocks the alpha4-dependent cellular respons

262 the alpha-4,3 family of alpha-conotoxins and selectively blocks the alpha9alpha10 nAChR subtype, in c

263 icking of internalized Ag-BCR complexes, and selectively blocks the BCR-mediated processing and prese

264 ICG-001 selectively blocks the beta-catenin/CBP interaction with

265 elated peptide antagonist [CGRP-(8-37)] that selectively blocks the calcitonin gene-related peptide r

266 Knockdown of Rpl22 in zebrafish embryos selectively blocks the development of T lineage progenit

267 ptide was expanded into a larger ligand that selectively blocks the E17K Akt1 interaction with its PI

268 otope tracing methods, to establish that 968 selectively blocks the enhancement in glutaminolysis nec

269 ammation, primarily through a mechanism that selectively blocks the expression of pro-inflammatory ge

270 al reduction of striatal dopamine levels and selectively blocks the induction of long-term potentiati

271 loped an anti-FGF19 monoclonal antibody that selectively blocks the interaction of FGF19 with FGFR4.

272 velopmentally regulated RNA binding protein, selectively blocks the processing of pri-let-7 miRNAs in

273 etion were largely blunted by AMD3100, which selectively blocks the SDF1 receptor CXCR4.

274 d invasion of diverse sarcoma cell types and selectively blocks the survival of bone sarcoma cells.

275 The K120R mutation selectively blocks the transcription of proapoptotic tar

276 Akt inhibition selectively blocks the transcriptional activation of Ets

277 Saxitoxin (STX) selectively blocks the voltage-gated sodium channel at t

278 s, enhancing phosphorylation of GABA(A)Rs or selectively blocking their interaction with AP2 may prov

279 outes; however, because of the difficulty in selectively blocking these routes in vivo, their roles i

280 ubtypes, alpha3beta2 versus alpha6beta2, and selectively blocks these two subtypes when compared with

281 ect the inhibition of IP6K2, suggesting that selectively blocking this interaction could provide effe

282 rived compound, sparstolonin B (SsnB), which selectively blocks TLR2- and TLR4-mediated inflammatory

283 FP7 selectively blocked TLR4 stimulation, but not TLR1/2, TL

284 ain inhibitors, antimycin A and myxothiazol, selectively blocked TNF-alpha-inducible expression of Mn

285 -inhibitor, DRB, or by small interfering RNA selectively blocked TNFalpha stimulation of IL-8 mRNA pr

286 binding moiety [TNFRI-AlbudAb]) was used to selectively block TNFRI.

287 nterest in pharmacological agents capable of selectively blocking tonically activated NMDARs while le

288 luble glycoprotein 130 fusion protein, which selectively blocks trans-signaling, was injected after 3

289 WT AAK1 overexpression selectively blocks transferrin (Tfn) receptor and LRP en

290 l subunits containing synthetic 18S rRNAs by selectively blocking translation from endogenous (pactam

291 ibodies against the Kex2p and Vps10p C-tails selectively block transport of Kex2p and the Kex2-Vps10p

292 We conclude that Srs2 selectively blocks triplet repeat expansions through its

293 ted the NGF-induced endocytosis of TrkA, and selectively blocked TrkA-mediated cytoplasmic signaling

294 ontraction coupling, using 200 nmol/L TTX to selectively block TTX-sensitive INa.

295 Deficiency of tPA selectively blocked tubular epithelial-to-myofibroblast

296 We show that TGZ selectively blocked tumor necrosis factor-alpha-induced

297 factor 1 (SDF-1) and VCAM-1, which could be selectively blocked using a specific CXCR4 inhibitor and

298 at blocks the alpha(4)-paxillin interaction, selectively blocked VCAM-1 stimulation of alpha(L)beta(2

299 te in collagen XIII for alpha1beta1 integrin selectively block VLA1-positive monocyte migration in tr

300 ic" signaling, and this Ca(2+) influx can be selectively blocked without reducing cardiac contractili