ライフサイエンスコーパス: selenite

1 , and extensively, throughout the grain than selenite.

2 the selD or the xdh mutant upon addition of selenite.

3 erevisiae, catalyzes high-affinity uptake of selenite.

4 ration of reactive oxygen species induced by selenite.

5 peroxide production and apoptosis induced by selenite.

6 elenate but were low in plants supplied with selenite.

7 rticles of elemental selenium (nano-Se) from selenite.

8 ins were up-regulated by chronic exposure to selenite.

9 ponic solution supplemented with selenate or selenite.

10 uced in rats by a single injection of sodium selenite.

11 hat selenate was taken up 2-fold faster than selenite.

12 vol) fetal bovine serum and 0.1 microM [75Se]selenite.

13 ble Se was comprised of Se oxyanions, mainly selenite.

14 ximately 1 mm from the apex) when exposed to selenite.

15 or the crystallization of templated vanadium selenites.

16 al cell bodies were also stained with either selenite (1 hr) or 6-methoxy 8-para-toluene sulfonamide

17 dicates that, in LB medium supplemented with selenite (1 mM), reduction to nano-Se occurs at a rate o

18 Se converted to organic forms was higher for selenite (100%) than for selenate (26%), the absolute co

19 with respect to GPx induction as was sodium selenite (2.2-fold increase at 15 microM).

20 edia containing increasing amounts of sodium selenite (30, 50, and 80 nmol/L).

21 Sodium selenite, a representative of the genotoxic selenium poo

22 We have found that sodium selenite, a selenium compound with chemotherapeutic pote

23 showed that overexpression of Jen1p enables selenite accumulation in yeast compared with a JEN1 knoc

24 indicating the Jen1p transporter facilitates selenite accumulation inside cells.

25 Our results in selenite-adapted cells suggest that selenium may exert i

26 male mice were fed a semipurified diet with selenite added as the source of selenium.

27 sms by which selenium, in the form of sodium selenite, added to serum-free growth medium regulates TR

28 in the medium (NO2- and NO3-) resulted from selenite addition to cell suspensions.

29 vation of intracellular calcium levels after selenite administration resulted in increased levels of

30 The mechanism of selenite adsorption by the new mixed adsorbent composed

31 Herein, the mechanism of selenate and selenite adsorption on NU-1000 is explored to determine

32 esults show that P. putida is able to reduce selenite aerobically, but not selenate, to nano-Se.

33 LNCaP cells treated with selenite also showed p53 translocation to mitochondria,

34 ed in the presence of up to 1.5 mM NaCl, and selenite analysis is even more robust against chloride.

35 G) and glutathione disulfide are formed from selenite and 4 GSH.

36 the Recommended Dietary Allowance of sodium selenite and antiretroviral drugs (ARV) on maternal plas

37 vector-only control plants when treated with selenite and exhibited an increased tolerance to Se.

38 In addition, selenite and lactate can inhibit the transport of each o

39 Se, whereas muskgrass contained Se mainly as selenite and organic Se forms.

40 tRNA(Sec) in vitro in the presence of sodium selenite and purified recombinant E. coli selenophosphat

41 PC3 cells increased cellular sensitivity to selenite and resulted in increased superoxide production

42 ate differences in selenium speciation, with selenite and selenate co-occurring in most samples.

43 lenocysteine and inorganic selenium species (selenite and selenate) were not detected in the dialyzat

44 Besides selenite and selenate, selenosulfate was the most freque

45 Both selenite and selenate, two major inorganic forms of Se,

46 ine, l-selenocystine, methaneseleninic acid, selenite and selenate.

47 ansported to the grain more efficiently than selenite and selenate.

48 ae were also exposed to waterborne dissolved selenite and to dietary selenomethionine as selenized al

49 the form of Se-supplemented (0.4 ppm; sodium selenite) and high Se (1.0 ppm; sodium selenite) diets.

50 <0.01 ppm Se), Se-adequate (0.08 ppm; sodium selenite), and two supraphysiological levels in the form

51 s" and related oxidation products, selenate, selenite, and other species relatable to the quality and

52 We also measured whether oxidized selenium, selenite, and reduced selenium, selenide, would target t

53 nic or organic species of Se (e.g. selenate, selenite, and Se-methionine [Met]) into gaseous Se forms

54 ied with selenate, 38 times higher than from selenite, and six times higher than from SeMet.

55 and MeHgCl) and Se (selenomethionine, sodium selenite, and sodium selenate) compounds.

56 SeMSC accumulation in response to selenate, selenite, and sulfate treatments showed that the BoSMT t

57 re treated with increasing concentrations of selenite, and the effects on DNA-binding activity of NF-

58 The diversity of the selenite anions as an inorganic ligand is demonstrated b

59 ir ability to adsorb and remove selenate and selenite anions from aqueous solutions.

60 ers) occurred at a much higher rate than for selenite (apparently by both passive diffusion and phosp

61 With selenite as the selenium source and the isolated reduced

62 o accumulate selenium by growing with sodium selenite as the selenium source under hydroponic conditi

63 that oxidative stress was induced by sodium selenite at high concentrations in both acute and chroni

64 of loss of cell viability induced either by selenite at pharmacological levels or by growth factor d

65 The observed proton conductivity of the selenite based oxothiometalate species renders them as p

66 differential cytotoxicity observed by sodium selenite between HCT116 and HCT116+Chr.3 cell lines was

67 s was shown by monitoring the consumption of selenite by bacteria incubated in LB broth.

68 ave strong implications for the retention of selenite by corrosion products in nuclear waste reposito

69 Limited studies have shown that selenite can also be immobilized through abiotic precipi

70 It is widely understood that selenite can be biologically reduced to elemental seleni

71 e, but in higher toxic levels (>5-10 microM) selenite can react with essential thiol groups on enzyme

72 he lens nucleus coincident with the onset of selenite cataract.

73 After acute exposure to selenite, cells exhibited mitochondrial injury and cell

74 After chronic exposure to selenite, cells showed growth inhibition caused by cell

75 - to 3-fold higher from plants supplied with selenite compared with selenate.

76 sprouts that were treated with a high sodium selenite content (2mg/100g seeds).

77 an SG assembly and provide insights into how selenite cytotoxicity may be exploited as an anti-neopla

78 supplemented for 6 wk with 100 microg sodium selenite/day.

79 odium selenite) and high Se (1.0 ppm; sodium selenite) diets.

80 increasing selenite levels and, at 7 microM selenite, DNA-binding activity was completely inhibited.

81 th the exception of Salmonella culture using selenite enrichment for which PCR was less sensitive tha

82 Selenite exposed periphyton readily bioconcentrated Se w

83 Selenite exposures resulted in high mortality to embryos

84 icles in the presence of EPS, extracted from selenite fed anaerobic granular sludge, yielded stable c

85 adpoles were exposed to dissolved (75)Se (as selenite) for 7 days and depurated until completion of m

86 as sole electron donor in the reaction with selenite, further conversion of the R-SSeS-R product app

87 e resistance, and overexpression resulted in selenite hypersensitivity.

88 much less toxic to the cells than was sodium selenite (IC(50) approximately 17 microM) or the parent

89 The improved understanding of selenite immobilization and the improved model can help

90 at both pathways significantly contribute to selenite immobilization in a microfluidic flow cell havi

91 Jen1p transported selenite in a proton-dependent manner which resembles th

92 S assimilation enzymes were up-regulated by selenite in Col-0 but not Ws-2.

93 ing the cataract formation induced by sodium selenite in male Wistar rat pups.

94 Selenate was metabolized less than selenite in whole plants, but in grains selenium was pre

95 Glutathione redox status was reduced by selenite in Ws-2 but not in Col-0.

96 lf, there was 30% inorganic Se (selenate and selenite) in addition to 70% MeSeCys.

97 Our previous study showed that sodium selenite induced LNCaP human prostate cancer cell apopto

98 We showed that selenite-induced apoptosis as evidenced by cleavage of p

99 In the current study, we show that selenite-induced apoptosis involves DNA damage.

100 xpressing LNCaP cells were more sensitive to selenite-induced apoptosis than p53-null PC3 cells.

101 to involve DNA topoisomerase II (Top II) as selenite-induced apoptosis was reduced in Top II-deficie

102 Selenite-induced apoptosis was shown to involve DNA topo

103 In the present study, we showed that selenite-induced apoptosis was superoxide mediated and p

104 In the aggregate, these results suggest that selenite-induced apoptosis, which involves ATM/ATR and T

105 In contrast, selenite-induced apoptotic DNA fragmentation was observe

106 N-acetylcysteine amide-only group, a sodium selenite-induced cataract group, and a NACA-treated sodi

107 in the NACA-treated group than in the sodium selenite-induced cataract group.

108 ed cataract group, and a NACA-treated sodium selenite-induced cataract group.

109 c sites of MIP N- and C-terminal cleavage in selenite-induced cataractous lenses were identified.

110 Macroarray analysis showed more pronounced selenite-induced increases in mRNA levels of ethylene- o

111 Selenite-induced SGs differ from canonical mammalian SGs

112 Selenite-induced SGs lack several classical SG component

113 Selenite-induced up-regulation of GPx (glutathione perox

114 These results suggest that selenite induces apoptosis by producing superoxide to ac

115 Selenite inhibition was reversed by addition of a dithio

116 V of the spinal cord were stained by sodium selenite injected intrathecally.

117 Furthermore, sodium selenite- injected rat pups had significantly higher lev

118 siderite is essentially a two-step process, selenite ions being immobilized on siderite surface prio

119 Therefore, we postulate selenite is a molecular mimic of monocarboxylates which

120 readily internalized by C. reinhardtii, but selenite is accumulated around ten times more efficientl

121 The reduction of selenate to selenite is catalyzed by a selenate reductase, previousl

122 Inhibition of NF-kappaB activity by selenite is presumed to be the result of adduct formatio

123 Soluble tetravalent selenite is the predominant environmental form and also

124 (DMEM) containing insulin-transferrin-sodium selenite (ITS) supplement (DMEM/ITS) or 10% fetal bovine

125 e DMEM containing insulin-transferrin-sodium selenite (ITS) with 10, 100, and 1000 pg/mL TGF-beta1 or

126 ts was decreased progressively by increasing selenite levels and, at 7 microM selenite, DNA-binding a

127 Se volatilization from selenite may be limited by selenite uptake and by the co

128 , S-nitrosoglutathione, selenodiglutathione, selenite, methylseleninate, and selenocystine.

129 ells with a gradient concentration of sodium selenite, methylseleninic acid and methylselenocysteine

130 n media containing various concentrations of selenite, molybdate, and various purine substrates.

131 nate was 9-fold more toxic to the roots than selenite, most likely due to increased accumulation of o

132 rminated after soaking with different sodium selenite (Na2SeO3) concentrations (0, 1 and 2mg/100g see

133 d fastest uptake rates for both selenate and selenite, of all zirconium-based MOFs studied here.

134 r chemopreventive agents and less toxic than selenite or certain naturally occurring selenoamino acid

135 ivities of PH and XDH, increased when either selenite or molybdate was added to the culture medium.

136 on processes for groundwater contaminated by selenite or other contaminants (e.g., uranium(IV)) that

137 With either selenite or selenate as substrates, Se methylation was h

138 atch reactor experiments were performed with selenite or selenate by equilibrating suspensions contai

139 gna unguiculata) exposed to either 20 microM selenite or selenate.

140 es of radioactive selenium 75 in the form of selenite or selenide and measured blood and tissue selen

141 , (ii) that are highly electrophilic such as selenite, or (iii) that are activated by strain such as

142 amended with the selenium oxyanion selenate, selenite, or selenocyanate, produces volatile organosele

143 B damage to DNA and modulation by vitamin C, selenite, or Trolox, a water-soluble vitamin E analog.

144 eMet and SeMet (but no DMSeP) accumulated in selenite- or SeMet-supplied wild-type plants and in sele

145 um of 8.5 and is also found to function as a selenite oxidase.

146 ics the reaction zone along the margins of a selenite plume undergoing bioremediation in the presence

147 Selenite pretreatment of NB4 cells increases the activit

148 manner and supplementation of 100 nM sodium selenite prevented the detrimental effects of glutamate

149 At GSH-to-selenite ratios >4:1, conversion of GSSeSG to a perselen

150 combination of reference spectra showed that selenite reaction with siderite is essentially a two-ste

151 A novel nitrate- and selenite reducing bacterium strain ZYK(T) was isolated f

152 eine thiol groups in reduced rSeBP prevented selenite reduction and selenium binding under comparable

153 regation of the more thermodynamic favorable selenite reduction and the less thermodynamically favora

154 rous oxides, is the main reason for its high selenite removal performance demonstrated by batch and c

155 III) hydrous oxides played a leading role in selenite removal.

156 Conversely, the selenite resistance of Col-0 was reduced in mutants impa

157 Disruption of JEN1 resulted in selenite resistance, and overexpression resulted in sele

158 ndex demonstrated a clear difference between selenite-resistant Col-0 and selenite-sensitive Ws-2.

159 ppb Se) and 380 nM (30 ppb) for selenate and selenite, respectively.

160 use high levels of molybdate, tungstate, and selenite restored growth to wild-type levels, this trans

161 0 micrograms/ml Trolox, and 5 or 12.5 microM selenite resulted in a significant decrease in the numbe

162 rphous elemental selenium precipitate on the selenite-rich side of the mixing zone, while long crysta

163 In the form of selenite (Se((IV))), selenium can be incorporated into c

164 When injecting selenite (Se((IV))), the precipitates grew significantly

165 rite and sphalerite, 19% of Se is present as selenite (Se(4+)) in barite, 21% of Se is present as exc

166 method, the predominant selenium oxyanions, selenite (Se(IV)) and selenate (Se(VI)), can be quantifi

167 or five selenium species; selenate (Se(VI)), Selenite (se(IV)), selenocysteine (SeC), Se-methylseleno

168 ure medium, but only when molybdate (Mo) and selenite (Se) were also added.

169 in QD exposures, we examined the toxicity of selenite, selenate, and amorphous selenium nanoparticles

170 ntaining anions examined were selenocyanate, selenite, selenate, tellurite, and tellurate.

171 ed and reduced into various inorganic forms (selenite, selenide, or elemental Se) or partially incorp

172 Selenite, seleno-cystine, and seleno-methionine exert th

173 olism of common dietary selenium compounds - selenite, selenomethionine, methylselenocysteine and sel

174 The selenite-sensitive phenotype of Ws-2 was attenuated by t

175 ference between selenite-resistant Col-0 and selenite-sensitive Ws-2.

176 reduction-oxidation reaction between aqueous selenite (SeO(3)(2-)) and siderite (FeCO(3(s))) was moni

177 The common selenium oxoanions selenite (SeO3(2-)) and selenate (SeO4(2-)) are toxic at

178 AtSBP1 binds selenium after incubation with selenite (SeO3(2-)) with a ligand to protein molar ratio

179 ubsequent toxicity to consumers of dissolved selenite (SeO3) versus selenate (SeO4) uptake into aquat

180 Simultaneous treatment of selenate with selenite significantly reduced SeMSC production.

181 nsgenic seedlings tolerated Se, particularly selenite, significantly better than the wild type, produ

182 ls were treated with selenocompounds (sodium selenite, sodium selenate, Se-Met, MeSeCys) or SeB [high

183 ated in growth compost irrigated with sodium selenite solution increased by 28- and 43-fold compared

184 administered sodium hydroselenide and sodium selenite solutions (0.05-2.4 mg/kg).

185 capsaicin treatment, which had no effect on selenite stain or MT-III mRNA content in small-diameter

186 When assessed 1 hr after sodium selenite, stain was distributed throughout the neuropil

187 Selenite supplementation of HIV-infected Malawian women

188 x-ray absorption spectroscopy revealed that selenite-supplied plants accumulated organic Se, most li

189 For both selenate- and selenite-supplied plants, Se accumulation and volatiliza

190 SRM selective inhibitors including selenate, selenite, tellurate, tellurite, nitrate, nitrite, perchl

191 ransverse mixing zone between propionate and selenite that mimics the reaction zone along the margins

192 mpare acute versus chronic effects of sodium selenite, the latter most closely resembling human clini

193 When grown in the presence of selenate or selenite, these bacteria produced both organo-sulfur and

194 ith plants supplied with SeMet, selenate, or selenite; they also accumulated more Se in shoots than i

195 steps in Se volatilization from selenate and selenite, time- and concentration-dependent kinetics of

196 cular mimic of monocarboxylates which allows selenite to be transported by Jen1p.

197 hr) that allows retrograde transport of zinc selenite to cell bodies, only small-diameter neurons and

198 Although the addition of sodium selenite to the growth medium did not affect phage produ

199 xide, which is produced upon the addition of selenite to TSBG.

200 Selenite-treated grains accumulated more selenium.

201 cumulated mainly in the leaves compared with selenite-treated plants where the selenium was retained

202 e peptides inhibited cataract development in selenite-treated rats, which was accompanied by inhibiti

203 Selenite treatment resulted in high levels of superoxide

204 olumbia (Col)-0 and Wassilewskija (Ws)-2, to selenite treatment.

205 aspase-9 activation, and apoptosis following selenite treatment.

206 l p53, Bax, and p21(Waf1) proteins following selenite treatment.

207 r selenium bioavailability is increased with selenite treatment.

208 such as glutathione and cysteine, react with selenite under specific conditions to form selenotrisulf

209 )](54-) (1a), which is templated using eight selenite units and two iron(III) centers.

210 latilization from selenite may be limited by selenite uptake and by the conversion of selenomethionin

211 Selenite uptake by Jen1p had a Km of 0.91 mM, which is c

212 ninic acid, methylselenocysteine, and sodium selenite via reactive oxygen species and facilitates the

213 ryptic soy broth with 1% glucose (TSBG) when selenite was added.

214 Consistent with ATM/ATR involvement, selenite was also shown to stimulate Ser-139 phosphoryla

215 Selenite was bound to the material via inner-sphere comp

216 the generation of reactive oxygen species by selenite was higher in Col-0 than in Ws-2.

217 Sodium selenite was injected intraperitoneally on postpartum da

218 s that selenide reduced damage to the heart; selenite was not effective.

219 we also showed that superoxide production by selenite was p53 dependent.

220 tral evolutions showed that more than 60% of selenite was reduced at the siderite surface after 20 h

221 Selenite was retained at the point of grain entry.

222 Using purified human recombinant Top II, selenite was shown to induce reversible Top II cleavage

223 ation, whereas only approximately 10% of the selenite was translocated.

224 he cooking process the loss of Se, mainly as selenite, was about 7%.

225 All expected forms of selenium except for selenite were determined using LC-MS/MS technique.

226 The effects of selenite were suppressed by pretreatment with a syntheti

227 o foliar Se fertilisers (sodium selenate and selenite) were tested at four rates (0-10-20-40gha(-1))

228 e Se-containing substrates selenocystine and selenite with only slightly less activity than the wild-