ライフサイエンスコーパス: self-

1 ors and non-progressors were significant for self (2.13, SE=0.45, P<.001), partner (5.08, SE=0.59, P<

2 atment (70%), the uncertainty of benefits to self (29%), or that trials are done mainly to benefit fu

3 mechanisms that maintain unresponsiveness to self (a state known as self-tolerance) contributes to th

4 es the humoral immune response distinctly to self (AChR) versus foreign (KLH) antigens.

5 Responses to a self- administered questionnaire completed by parents of

6 Importantly, transfer of self- Ag-pulsed DCs overexpressing miR-155 was sufficien

7 rotective immune responses and tolerance to (self-)Ags.

8 cells have been shown to critically regulate self- and allograft tolerance in several model systems.

9 te of lower postprocedural gradients in both self- and balloon-expandable transcatheter valves.

10 The sensitivities of culture methods using self- and clinician-collected specimens were 84.6 and 88

11 n the sensitivities of culture methods using self- and clinician-collected vaginal specimens for the

12 A comparison of self- and clinician-collected vaginal specimens for the

13 Results with self- and clinician-collected VS were equivalent and wer

14 s were performed on FCU, urethral, cervical, self- and clinician-collected VS.

15 HPV), as well as specific HPV types, between self- and clinician-obtained specimens for 450 women ove

16 Nature provides many examples of self- and co-assembling protein-based molecular machines

17 re further studied by in vitro binding using self- and cross-competition.

18 , were shown to signal for calcium flux in a self- and cross-desensitizing manner, implicating a sing

19 radiation transport was performed to assess self- and cross-doses for each cell nucleus in a populat

20 ptional level through a complex circuitry of self- and cross-regulatory RNP interactions.

21 e segments induced amyloid formation through self- and cross-seeding.

22 We discuss why and how a combination of self- and directed-assembly processes, involving interpa

23 tions for use as placeholders in intelligent self- and directed-assembly.

24 erstitials control basic processes, foremost self- and dopant diffusion.

25 There was an excellent agreement between self- and DOT-reports.

26 ed but poorly understood phenomenon of mixed self- and foreign Ag reactivity in the CD1 system.

27 KTC process and present self- and foreign Ags for immune recognition by CD4+ T c

28 B10 cell-derived IgM reacted with both self- and foreign Ags, whereas B10 cells generated Ag-sp

29 The mechanisms that discriminate self- and foreign antigen before T cell activation are u

30 Regulation of the immune response to self- and foreign antigens is vitally important for limi

31 an antibody response to specific epitopes of self- and foreign antigens that lead to a neutralizing i

32 xhibited reduced capacity to present several self- and foreign antigens to Kb-, Db-, or Qa-1b-restric

33 Until recently, sequence homology between self- and foreign antigens was considered necessary for

34 NKT TCR recognition of self- and foreign antigens was underpinned by a similar

35 These findings apply to both self- and foreign antigens, as well as memory and naive

36 ion and block tolerance to tumor-associated, self- and foreign antigens.

37 brake on responses of T and B lymphocytes to self- and foreign antigens.

38 CD8(+) T cells were hyper-responsive towards self- and foreign antigens.

39 CD1 proteins present self- and foreign lipid Ags to activate specific T cells

40 ple different intracellular compartments for self- and foreign lipids.

41 have alphabeta TCRs that can recognize both self- and foreign peptide-MHC (pMHC) complexes, implying

42 ponsive to homeostatic signals and recognize self- and foreign peptides in the context of self-MHC an

43 be to quantitatively examine a collection of self- and foreign peptides that bind to L(d).

44 Vgamma2Vdelta2 T cells are stimulated by self- and foreign prenyl pyrophosphate intermediates in

45 is endocytosed proteins, which includes both self- and foreign proteins.

46 ll receptors (TCRs) can crossreact with both self- and foreign- major histocompatibility complex (MHC

47 urities, and a quantitative understanding of self- and foreign-atom diffusion in semiconductors is ce

48 ity of the CD4(+) T-cell compartment to bind self- and foreign-pMHC changes over the lifespan remains

49 itionally, we discuss driving mechanisms for self- and guided assembly to create micro-to-macro scale

50 The values of equilibrium constants for both self- and heteroassociation may be determined with reaso

51 Many weaker self- and heteroassociations were also detected by CD, F

52 The shared view of self- and informant-rated attention problems is highly h

53 Regions of high self- and inter-side-chain dynamical correlations are fo

54 the silver-copper cyanide networks are both self- and interpenetrating, features also seen in the kn

55 s and act as a conduit for the processing of self- and intestinally absorbed antigens, leading to the

56 and behavioral problems were measured using self- and maternal-reported symptoms of depression, anxi

57 the regulation of human immune responses to self- and microbial antigens, an important role of suppr

58 pe (SE) alleles were predicted to bind these self- and microbial peptides strongly, and these respons

59 Also significant were self- and mother-reported internalizing behaviors, as we

60 If the self- and nearby connections are absent (off-center), pr

61 otypic NAA, ppc1-5, which binds a variety of self- and non-self-Ags including DNA and phosphocholine.

62 tion of persisting T lymphocytes reactive to self- and non-self-antigens is a major arm of operationa

63 Moreover, self- and non-self-antigens, such as apolipoprotein B-10

64 ot m66) exhibited polyspecific reactivity to self- and non-self-antigens.

65 planned actions and permit discrimination of self- and non-self-elicited sensation; their impairment

66 agency, the ability to discriminate between self- and non-self-generated events.

67 olerance and reactivity to strong activating self- and non-self-ligands remained largely intact.

68 cell-mediated host immune responses against self- and nonself-antigens; however, the impact of CD4(+

69 In contrast, NK cells expressing self- and nonself-HLA class I-binding inhibitory killer

70 What limits this second layer of self- and nonself-reactive Treg production in physiologi

71 Self- and observer-rated cognitive measures were similar

72 nd exploratory outcomes included craving and self- and observer-rated global functioning on the Clini

73 Both self- and observer-rated scores on the Rating for Premen

74 ffected by sedation), short-term memory, and self- and observer-rated sedation were assessed in 18 pa

75 During both self- and other-committed errors activation was seen in

76 neural matching mechanism believed to couple self- and other-generated facial gestures.

77 Nervous systems distinguish between self- and other-generated movements by monitoring discre

78 rmation (vision) during incongruency between self- and other-related affective states.

79 es, e.g., memory and social evaluation, with self- and other-related information processed in dissoci

80 findings suggest (i) that the full array of self- and pathogen-derived epitopes available during thy

81 overlapping binding sites for recognition of self- and pathogen-expressed ligands.

82 Although both self- and pathogen-specific T cells can participate in t

83 r interviews, scores using an "and" rule for self- and peer reports, and separate tests for externali

84 ate self-harm, self-harmers scored higher on self- and peer-report measures of borderline, schizotypa

85 We find that EBV does persist within self- and polyreactive B cells but find no evidence that

86 ies were highly mutated but the frequency of self- and polyreactive IgG antibodies was significantly

87 Whether self- and polyreactive IgG-secreting B cells are also to

88 n by mechanisms that limit the production of self- and polyreactive serum IgG antibodies.

89 nt characterized by relatively low levels of self- and polyreactivity.

90 nt during acute infection and profiled their self- and polyreactivity.

91 analysis was to examine the effectiveness of self- and professionally applied fluoride and water fluo

92 s published after/during 1980, any fluoride (self- and professionally applied or water fluoridation)

93 vent, are the result of an interplay between self- and protein-driven assembly processes that unite i

94 ved from the murine folate receptor alpha, a self- and tumor Ag, was modified at its carboxyl terminu

95 unosuppressive cytokine known to impede both self- and tumor-specific T cells, but its role in regula

96 at CD134 (OX40) costimulation programs naive self- and virus-reactive CD4 T cells to undergo in vivo

97 ressing an appropriate specificity when the (self-) antigen is present.

98 STING homodimers were able to complex with self- (apoptotic, necrotic) or pathogen-related ssDNA an

99 They react to a growing list of self- as well as non-self-lipid ligands, and share some

100 ss of dynamic bulk polymeric materials that (self-) assemble via the transport of cross-links or defe

101 viruses, and the recombinant capsid proteins self- assembled into virus-like particles (VLPs) that we

102 active immunization agent targeting amyloid self- assembly in a diabetes-associated phenotype transg

103 such as DNA, proteins, and lipids, for the (self-) assembly of new structures for applications in bi

104 n Resource) and MKSAP (Medical Knowledge and Self- Assessment Program).

105 The motion of host-lattice ('self-') atoms in solids is mediated by point defects suc

106 fficient proportions (pH = pKa +/- 1.6): (i) self-/autocatalysis and (ii) sequential disproportionati

107 ffect were less likely to prefer self/mostly self (autonomous decision making).

108 ongest predictors being perceived benefit to self (beta = .21, p<.01), the U.S. (beta = .19, p<.01),

109 is approach was demonstrated using viral and self-(differentiation) antigens as models.

110 , in mice with Ig transgenes coding for anti-self (DNA) Ab, we report dsDNA breaks indicative of ongo

111 Deletion or inactivation of anti-self (DNA) B cells has been reported in non-autoimmune m

112 4.60, 95 % CI: 1.01-21.03, p < 0.049), being self - employed (AOR = 6.14, 95 % CI: 1.37-27.50, p < 0.

113 idual stenosis it was decided to implant two self - expanding stents 10x40 mm.

114 mbination) over generations is described for self-, full-sib-, and half-sib-generated RILs with no do

115 twins into 5 possible categories: trauma to self (further divided by severity), observed trauma to o

116 response against self (i.e., tumors) and non-self (i.e., bacterial, worm, and viral infections).

117 atory CD4(+) T cells in the response against self (i.e., tumors) and non-self (i.e., bacterial, worm,

118 Fifteen self- inactivating (SIN) lentiviral vectors using 4 eryt

119 uced primary CD8(+) T-cell responses against self (MART-1) and viral (HIV gag) antigens.

120 acteristics and physical significance of the self-, Maxwell-Stefan, and Fick diffusivities are explai

121 test for the United States (mean = 5.56) and self (mean = 5.39) compared to the target population (me

122 to study this question, given the variety of self-, microbiota- and food-derived antigens to which Tr

123 bears the direct imprint of the hierarchy of self (ML)-determinants.

124 determinants within ML and the anti-cryptic, self (ML)-directed T cell repertoire.

125 Although the observer's own (self-)motion affects the object's pattern of motion on t

126 When observer (i.e., self-)motion is accompanied by object motion, the optic

127 a higher responsiveness to the corresponding self (mouse) aggrecan peptide, and produced more inflamm

128 ion between two Th cells, one specific for a self (MUC.1) and the other for a nonself T cell determin

129 i.m.) injection with identical RDAd encoding self (murine) or foreign (human) erythropoietin.

130 Self-/non-self-recognition between pollen and pistil is

131 ic polymorphism, are ancient determinants of self-/non-self-recognition.

132 allelic protein HET-S causes cell death in a self-/nonself-discrimination process.

133 results support a role for siglecs in B cell self-/nonself-discrimination, namely suppressing respons

134 r fluids constitute an alternative source of self- or allopeptides for DCs during maintenance of peri

135 iniscent of the way autoreactive TCRs engage self- or altered self-peptides, consistent with the tole

136 ar to that of IAPP but have distinct amyloid self- or cross-interaction potentials.

137 described RNA ligase that can undergo either self- or cross-replication but had been limited in its a

138 owever, the results may be influenced by the self- or departmental selection of participants who were

139 ing antigen, irrespective of whether it is a self- or foreign antigen.

140 in unknown, including whether they recognize self- or foreign antigen.

141 antly abrogated T-cell-mediated responses to self- or islet-specific peptides ex vivo.

142 eurysmal lesion, in response to unidentified self- or nonself Ags.

143 different MHC I heavy chains with a defined self- or nonself-peptide presented, on cultured embryoni

144 oral tendencies are generally measured using self- or observer-report.

145 essment of fight outcome rather than just on self- or opponent-only assessment of fighting ability.

146 of immunoglobulins, some of which recognize self- or parasite-specific antigens.

147 ubstance abuse psychiatric problem (based on self- or peer interview) at age 25, in contrast with 59%

148 pe (SPT) has been determined subjectively by self- or trained investigator assessment using sun burni

149 double-nested pseudoknot, and for efficient self- (or cis-) cleavage.

150 in the body reside, dysregulated immunity to self (or the extended self, the diverse microbiota that

151 nts of mentalization can be organized around self-/other-oriented, implicit/explicit, and cognitive/a

152 ss at the time of study entry; (3) receiving self-, parent-, or caregiver-administered oral 6MP durin

153 sence of gluten in these subjects leads to a self- perpetuating mucosal damage, and the elimination o

154 l memory,) compared with knowledge about the self (personal memory), for recent compared with distinc

155 Using self - phase modulation experiments, we characterize a w

156 ains from two other HIV-1 Abs, 4E10 (another self-/polyreactive, anti-gp41 BnAb) and 48d (an anti-CD4

157 R = 0.22, 95 % CI: 0.06-0.77, p < 0.019) and self - purchasing of medications (AOR = 0.30, 95 % CI: 0

158 ed a vigorous T cell response both to 65-kDa self (rat) heat shock protein (Rhsp65) and mycobacterial

159 pe specificity of tolerance to the mammalian self (rat) homologue of Bhsp65, 65-kDa rat heat-shock pr

160 terial heat shock protein (hsp) 65 (Bhsp65), self (rat) hsp65 (Rhsp65), and linear peptides spanning

161 cell repertoire, and the role of homologous self (rat) hsp65 (Rhsp65), if any, in spreading of the T

162 presentation of allogeneic MHC molecules by self (recipient) APCs.

163 tigens as processed peptides associated with self (recipient)-MHC class II molecules.

164 recognized to support processes of internal (self-) reference that predominate in states of rest and

165 t noncoding RNAs that are implicated in cell self- renewal and cancer development.

166 each subset are remarkably similar in their self- renewal and differentiation behaviors, to the poin

167 egulation and reduces cell proliferation and self- renewal to adult levels.

168 ces than referents of chronic bronchitis and self- reported asthma and emphysema.

169 ignificant cross-sectional associations with self- reported HCU and with both generic and disease-spe

170 ETS) at work (PR 1.8; 95% CI 1.1 to 3.1) and self- reported job exposure to vapors, gases, dust, or f

171 relationship of eNO was found to serum IgE, self- reported smoking, or glucocorticoid use.

172 f (that is to be attacked) and noninfectious self (that must not be attacked).

173 elf-expression linked to active parts of the self (the active self), enhancing confidence, self-regul

174 vaccinated with a fusion protein containing self (TNF-alpha) and foreign (streptavidin) components,

175 A comparison of Ab responses against the self (TNF-alpha) and foreign components of the fusion pr

176 We show that self-/tumor-reactive effector memory CD8(+) T cells (T(E

177 Nedd4-2 undergoes self- ubiquitination and degradation.

178 chondrial membrane potential, caused by its (self-)ubiquitination, followed by degradation via the ub

179 This divergence of self- versus allo-MHC-restricted allosensitization for D

180 ing a potentially synergistic role for it in self- versus nonself-mRNA discernment.

181 normal healthy controls were tested using a self- versus visual-motion psychophysical experiment.

182 op IDDM, which depends on Db-restricted anti-self (viral) CTL.

183 Adaptive cellular immunity requires accurate self- vs. nonself-discrimination to protect against infe