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1 , producing more compartments with increased self-replication.
2 mal scheduling naturally emerges in cellular self-replication.
3 es), an important stepping stone towards RNA self-replication.
4 e sequences have the property of spontaneous self-replication.
5 emonstrated how this system can give rise to self-replication.
6 pic properties and are capable of continuous self-replication.
7 eriodic behavior with fundamental aspects of self-replication.
8 etic restriction and capacity for autonomous self-replication.
9 ing on nucleic acid polymers, allowing their self-replication.
10 ing of complex cellular behaviors, including self-replication.
11 nitial darwinian selection was for molecular self-replication.
12 independent of any genomic functions beyond self-replication.
13 s increased sensitivity, responsiveness, and self-replication.
14 exponential growth of ribozymes that undergo self-replication.
15 can lead to increased responsiveness and to self-replication.
16 the smallest known microorganisms capable of self-replication.
17 ate would not have led to the termination of self-replication.
18 plex beyond its CAC, leading to the onset of self-replication.
19 talyze a critical reaction for prebiotic RNA self-replication according to the RNA world hypothesis.
21 etabolites and processing units required for self-replication and additionally requiring that these p
24 gence of an informational polymer capable of self-replication and its compartmentalization within pro
25 re the cellular regulation of conformational self-replication and its phenotypic effects, we analyzed
26 lls must select between alternative fates of self-replication and lineage commitment during continuou
28 turational lineage stages and yet capable of self-replication and multipotent differentiation, being
29 prebiotic synthesis to the emergence of RNA self-replication and precellular Darwinian evolution.
33 tributed over its surface, and the rules for self-replication are encoded into the specificity and st
34 icated that the new beta-cells were not from self-replication but arose through differentiation of po
38 ivo favors differentiation at the expense of self-replication, eventually resulting in a complete los
41 e origin of life, the feasibility of peptide self-replication has not been established experimentally
42 g the smallest and simplest cells capable of self-replication, has a distinct cellular polarity chara
47 despite the central importance of molecular self-replication in the origin of life, the feasibility
52 The emergence of an RNA catalyst capable of self-replication is considered a key transition in the o
54 cence, which leads to a diminished beta-cell self-replication, massive depletion of the pancreatic is
55 w, suggesting that there may be undiscovered self-replication mechanisms possible in much simpler sys
59 results demonstrate that TPO can mediate the self-replication of HSC in LTBMC, and provide proof that
60 ng orthogonal from each other: autocatalytic self-replication of oligomers from native monomers and n
61 s of such fundamental biological behavior as self-replication of structural elements and preservation
69 , temporally regulated viral expression, and self-replication proceeding to infection of new cells.
71 ditional template units for the nucleic acid self-replication process, resulting in the ultrasensitiv
72 tion of a hydrophobic pocket in water, (iii) self-replication properties and (iv) allosteric properti
76 Tfl (Thermus flavus)) and compartmentalized self-replication selection, we have evolved polymerases
77 re we describe short-patch compartmentalized self-replication (spCSR), a novel strategy to expand the
79 hBTSCs were similar in vitro with respect to self-replication, stemness traits, and multipotency.
81 l that ES cells have an innate programme for self-replication that does not require extrinsic instruc
82 what is probably the most iconic example of self-replication--the ability of a system to replicate,
83 ere is a reasonably wide parameter range for self-replication, there is a subtle balance between the
84 s of beta-cells predominantly occurs through self-replication; therefore, understanding the regulatio
87 not only remained intact but were capable of self-replication using native monomers as the substrate.
89 the consequences of hematopoietic stem cell self-replication will assist in the development of new a
91 smallest and simplest known cells capable of self-replication, yet it has a complex architecture with
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