ライフサイエンスコーパス: self-ubiquitination

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1 ting MDM2/MDM4 interaction and inducing MDM2 self-ubiquitination.

2 ly regulated by GDU1 ubiquitination and LOG2 self-ubiquitination.

3 FD, indicating that the RFD is essential for self-ubiquitination.

4 e p27, such a mutation has no effect on Skp2 self-ubiquitination.

5 on as E3 ligases based on their capacity for self-ubiquitination.

6 heir unique N termini, resulting in enhanced self-ubiquitination.

7 ger domain and plays a critical role in Mdm2 self-ubiquitination.

8 We demonstrate here that MDMX gains self-ubiquitination activity and becomes extremely unsta

9 activity and binding to p53, separating the self-ubiquitination activity of MDM2 from its ability to

10 Nedd4-2 undergoes self- ubiquitination and degradation.

11 stabilization of MDM2 through enhancing MDM2 self-ubiquitination and accelerating turnover rate.

12 stabilization of COP1 through reducing COP1 self-ubiquitination and decelerating COP1's turnover rat

13 d that AKR1C3 can bind Siah2 and inhibit its self-ubiquitination and degradation, thereby increasing

14 HAUSP interactions and thereby promoted MDM2 self-ubiquitination and degradation.

15 ing that E6-E6AP interaction results in E6AP self-ubiquitination and degradation.

16 n Sumo-1 conjugation, Mdm2 is protected from self-ubiquitination and elicits greater ubiquitin-protei

17 In vitro sumoylation of Mdm2 abrogates its self-ubiquitination and increases its ubiquitin ligase a

18 As Cbl-b self-ubiquitination and proteasomal degradation is impai

19 orylation-dependent manner and promotes Fbw7 self-ubiquitination and protein degradation by disruptin

20 These observations suggest that Nrdp1 self-ubiquitination and stability could play an importan

21 totype substrate Hmg2p-GFP, validating Hrd1p self-ubiquitination as a viable assay of ligase function

22 Ataxin-3 was found to counteract parkin self-ubiquitination both in vitro and in cells.

23 of Usa1p was required specifically for Hrd1p self-ubiquitination but not for degradation of either ER

24 chondrial membrane potential, caused by its (self-)ubiquitination, followed by degradation via the ub

25 dulates HECT domain activity, as measured by self-ubiquitination induced in the absence of this helix

26 In tissue culture, MTBP inhibits Mdm2 self-ubiquitination, leading to stabilization of Mdm2 an

27 CFSkp2 cannot ubiquitinate p27Kip1; instead, self-ubiquitination of Skp2 occurs.

28 om its binding to Ub chains on the E3 (after self-ubiquitination) or on the substrate, as a mutant la

29 o and in vivo experiments indicate that E6AP self-ubiquitination results primarily from an intramolec

30 ndent signaling triggered noncanonical TRAF3 self-ubiquitination that activated the interferon respon

31 dies revealed that 14-3-3sigma enhanced COP1 self-ubiquitination, thereby preventing COP1-mediated p5

32 tolerance to exogenous amino acids, and LOG2 self-ubiquitination was markedly stimulated by the GDU1

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