ライフサイエンスコーパス: semi-invariant

1 vated by CD1d-glycolipid complexes through a semi-invariant alphabeta T cell receptor (NKT TCR).

2 Natural killer T cells express a conserved, semi-invariant alphabeta T cell receptor that has specif

3 Thymocytes expressing the NKT cell semi-invariant alphabeta TCR are thought to undergo agon

4 Their semi-invariant alphabeta TCRs recognize isoglobotrihexos

5 ural killer T cells (NKT cells) expressing a semi-invariant CD1d-reactive T cell receptor (invariant

6 caque spleen-derived Valpha24(+) T cells are semi-invariant double-negative cells with effector memor

7 The semi-invariant MAIT T-cell antigen receptor (TCR) recogn

8 T TCR/MR1 complex structure explains how the semi-invariant MAIT-TCR engages the nonpolymorphic MR1 p

9 The semi-invariant natural killer (NK) T-cell receptor (NKTc

10 Semi-invariant natural killer T (NKT) cells are innate-l

11 Semi-invariant NKT cells are thymus-derived innate-like

12 mammalian phospholipids, demonstrating that semi-invariant NKT TCRs have a capacity for private Ag s

13 cells (NKT cells) characterized by either a semi-invariant T cell antigen receptor (TCR) repertoire

14 ted invariant T cells (MAIT cells) express a semi-invariant T cell receptor (TCR) alpha-chain, TRAV1-

15 ssociated invariant T (MAIT) cells express a semi-invariant T cell receptor (TCR) that detects microb

16 natural killer T (NKT) cells expressing the semi-invariant T cell receptor V(alpha)14J(alpha)18 requ

17 They express semi-invariant T cell receptors, which recognize glycoli

18 lls comprise a separate T lineage expressing semi-invariant T cell receptors.

19 rved alphabeta T-cell lineage that express a semi-invariant T-cell receptor (TCR) restricted to the M

20 ry T cells that comprise type I (express the semi-invariant T-cell receptor [TCR] and can be detected

21 Type I NKT cells use a semi-invariant T-cell receptor and react with alpha-gala

22 itive CD4+CD8+ thymocytes that rearrange the semi-invariant T-cell receptor found on mature NKT cells

23 ond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated

24 population characterized by expression of a semi-invariant T-cell receptor, rapidly produce copious

25 regulatory T cells that recognize CD1d via a semi-invariant TCR (iNKT-TCR).

26 ell-characterized type I NKT cells express a semi-invariant TCR and can recognize both alpha- and bet

27 -associated invariant T (MAIT) cells express semi-invariant TCR and restriction by nonclassical MHC c

28 NKT cells that express the semi-invariant TCR are innate-like lymphocytes whose fun

29 , posing the interesting question of how the semi-invariant TCR can bind to such structurally distinc

30 ulation characterized by the expression of a semi-invariant TCR capable of recognizing bacterial prod

31 ls, or invariant NKT (iNKT) cells, express a semi-invariant TCR characterized by its unique Valpha14-

32 tudies on NKT cells focused on a subset with semi-invariant TCR termed invariant NKT cells, the major

33 l-associated invariant T (MAIT) cells have a semi-invariant TCR Valpha-chain, and their optimal devel

34 In adults they dominantly express the semi-invariant TCR Valpha7.2, the canonical feature of m

35 ided into two groups: type I NKT cells use a semi-invariant TCR, whereas type II express a relatively

36 ecognize self-glycolipids by virtue of their semi-invariant TCR, which triggers NKT cell lineage comm

37 KT) cells have at least two subsets: type I, semi-invariant TCRalpha chain-expressing (Valpha14Jalpha

38 How expression of canonical semi-invariant TCRs leads to innate-like effector differ

39 Contrastingly, Vdelta2(+) T cells express semi-invariant TCRs, which are present at birth and shar

40 fraction of the autoreactive T cells express semi-invariant TCRs.

41 availability of potent Ags and tetramers for semi-invariant/type I NKT cells allowed this population

42 Semi-invariant/type I NKT cells are a well-characterized

43 Natural killer T (NKT) cells express a semi-invariant Valpha14 T cell receptor (TCR) and recogn

44 Invariant NKT (iNKT) cells expressing a semi-invariant Valpha14 TCR recognize self and foreign l

45 The semi-invariant Valpha14Jalpha18 T cell receptor (TCR) is

46 s that is dependent on their expression of a semi-invariant Valpha7.2(+) TCR.

47 KTgammadelta T cells uses TCRs composed of a semi-invariant Vdelta6.3/6.4-Ddelta2-Jdelta1 chain toget