ライフサイエンスコーパス: semicircular

1 determine the effects of a rowlike array of semicircular arclike membrane scaffolds on generation of

2 drophobic and ionic interactions between two semicircular beta monomers.

3 20 keV, in 1-keV increments) were input to a semicircular breast geometry of thicknesses from 2 to 12

4 We model this system as a semicircular bulge on a microchannel wall, with pressure

5 We imaged the horizontal semicircular canal (HSCC) crista and cupula of toadfish,

6 We found that both irregular otolith and semicircular canal afferents, because of their higher se

7 onents arise from stimulation of otolith and semicircular canal afferents, respectively.

8 ON and TON receive principally utricular and semicircular canal afferents.

9 ent in the apex and all three cristae of the semicircular canal ampullae.

10 to account not only for the gain of a third semicircular canal and crista in gnathostomes, but also

11 However, formation of the lateral semicircular canal and its ampulla is usually unaffected

12 l computations underlying the integration of semicircular canal and otolith inputs required for accur

13 f afferent fibers innervating the individual semicircular canal and otolith organs was produced by se

14 alone, with most showing convergence between semicircular canal and otolith signals.

15 l, fore-aft, vertical) for CSs and along the semicircular canal axes for SSs.

16 ursuit preferred-direction vectors along the semicircular canal axes was observed, the sensitivity of

17 volving the superior, lateral, and posterior semicircular canal can have different etiologies, includ

18 The present results show that the semicircular canal crista ampullaris of the toadfish, Op

19 ricle, and a complete loss of the horizontal semicircular canal crista, as well as a fusion of the ut

20 es the peripheral zones of each of the three semicircular canal cristae.

21 This force pushes on the semicircular canal cupula, leading to nystagmus.

22 s Chd7 deficiency have circling behavior and semicircular canal defects and are an excellent animal m

23 Posterior semicircular canal dehiscence is a rare entity, with sim

24 Superior semicircular canal dehiscence is now a well-established

25 Lateral semicircular canal dehiscence is usually associated with

26 The main focus will be on superior semicircular canal dehiscence.

27 by showing that the retinoic acid effect on semicircular canal development can be overcome by exogen

28 acent to the BMP4 cell foci prevented normal semicircular canal development.

29 del accounts for observed axis tilt based on semicircular canal directional sensitivity and response

30 In zebrafish and Xenopus, semicircular canal ducts develop when projections of epi

31 Morphogenesis of the semicircular canal ducts in the vertebrate inner ear is

32 asia, and ear defects including deafness and semicircular canal dysgenesis.

33 hour intervals during the critical stages of semicircular canal formation (E6-E7).

34 The defect in semicircular canal formation is due to problems in the i

35 BMP4 antagonists disrupt semicircular canal formation, as does exposure to retino

36 survival in the ear, for HC differentiation, semicircular canal formation, statoacoustic ganglion (SA

37 and disrupted hair cell differentiation and semicircular canal formation.

38 pment, Nor-1 is expressed exclusively in the semicircular canal forming fusion plates.

39 Semicircular canal geometries underwent distinct changes

40 Here we show that semicircular canal hair cells generate a mechanical nonl

41 ing activity after canal occlusions, but the semicircular canal input is critical for updating the ne

42 eives highly overlapping otolithic organ and semicircular canal input, and we propose that this regio

43 and the horizontal plane to determine their semicircular canal input.

44 d ventral MgON) receive mainly utricular and semicircular canal inputs, suggesting vestibular roles.

45 ay variable asymmetric lateral and posterior semicircular canal malformations, as well as defects in

46 The horizontal semicircular canal nerve of the toadfish, Opsanus tau, w

47 Each semicircular canal nerve projects to distinct regions of

48 eling the peripheral axons of the horizontal semicircular canal nerve with biocytin after nerve regro

49 Semicircular canal nerves project primarily to ventral r

50 egregated projections from all otolithic and semicircular canal nerves, whereas the ventral DON and T

51 re recorded from chinchillas after bilateral semicircular canal occlusion.

52 bers and varicosities were visualized in the semicircular canal of red-eared turtles (Trachemys scrip

53 behaviour due to truncations of the lateral semicircular canal of the inner ear.

54 lectrode placement with respect to bilateral semicircular canal pairs or alterations of the bipolar s

55 utgrowth and a failure of fusion to form the semicircular canal pillars.

56 lysis revealed smaller posterior and lateral semicircular canal primordia and a delay in the canal fu

57 While there is considerable evidence that a semicircular canal prosthesis that senses angular head v

58 ad significantly greater horizontal-vertical semicircular canal signal convergence than did neurons n

59 ess or near target viewing demonstrated that semicircular canal signals are necessary sensory cues fo

60 It is traditionally believed that semicircular canal signals drive compensatory responses

61 y storage network is to temporally integrate semicircular canal signals, so that they may be used to

62 ze that the unparalleled modification of the semicircular canal system represented a key 'point of no

63 an independent perspective by looking at the semicircular canal system, one of the main sense organs

64 r nuclei that overlapped with the horizontal semicircular canal terminal fields, whereas saccular aff

65 Contributions of semicircular canal versus otolith organ signals were inv

66 tegy that markedly differs from that used by semicircular canal vestibular afferents to encode rotati

67 of physiologically characterized horizontal semicircular canal vestibular nerve afferents in the toa

68 are usually attributed to the dysfunction of semicircular canal vestibulo-ocular reflexes, as they ha

69 and nuchal torus) and temporal labyrinthine (semicircular canal) morphology with the Neandertals.

70 d processes, superiorly positioned posterior semicircular canal, absence of a nuchal torus and a supr

71 Otolithic, semicircular canal, and anterior lateral line nerves all

72 In generating a semicircular canal, epithelial cells seem to 'disappear'

73 -/- mutants showed an absence of the lateral semicircular canal, lateral ampulla, utriculosaccular du

74 Ocular motor, semicircular canal-ocular, and semicircular canal-otolit

75 Ocular motor, semicircular canal-ocular, and semicircular canal-otolith interaction assessments sugge

76 ing focused on the otolith-ocular reflex and semicircular canal-otolith interaction.

77 sed by free-floating debris in the posterior semicircular canal.

78 chlea via virus injection into the posterior semicircular canal.

79 es of IK,L in type I hair cells of the mouse semicircular canal.

80 We hypothesized that a posterior semicircular canalostomy would induce apical flow from t

81 morphogenetic program that shapes the three semicircular canals (SSCs) must be executed with extreme

82 that stimulated both the otolith organs and semicircular canals (upright roll and on tail yaw) produ

83 d by a smaller vestibular organ with thinner semicircular canals and a significant reduction in the n

84 bout the anteroposterior axis, with only two semicircular canals and a single sensory macula.

85 rns the shape of vestibular components - the semicircular canals and ampullae - by conferring anterop

86 vestibular hair cells in the cristae of the semicircular canals and auditory hair cells in the organ

87 development of the dorsolateral otocyst into semicircular canals and cristae through two distinct mec

88 hlear hypoplasia and complete absence of the semicircular canals and cristae.

89 st), otolith formation, morphogenesis of the semicircular canals and differentiation of the otic caps

90 x6 expression is seen throughout the forming semicircular canals and endolymphatic structures.

91 receptor, TrkB, lose all innervation to the semicircular canals and have reduced innervation of the

92 bsd homozygotes lack endolymphatic ducts and semicircular canals and have short cochlear ducts.

93 g-eared mutants show abnormal development of semicircular canals and lack cristae within the ear, whi

94 for complicated stimuli, which activated the semicircular canals and otolith organs and involved both

95 in the vestibular system, which includes the semicircular canals and otolith organs.

96 ibular receptors consist of highly conserved semicircular canals and otolith organs.

97 y reflect the stimulus magnitudes handled by semicircular canals and otolith organs.

98 Signals from the receptors, the semicircular canals and otoliths, are carried by the eig

99 ll simultaneously stimulate receptors in the semicircular canals and otoliths.

100 sive loss of all afferent innervation to the semicircular canals and reduced innervation to the utric

101 , at larval stages zebrafish lack functional semicircular canals and rely exclusively on their otolit

102 In young subjects, natural engagement of the semicircular canals and the otolith organs by head rotat

103 regulator, is required for the formation of semicircular canals and their associated sensory cristae

104 ect angular head movements lies in the three semicircular canals and their sensory tissues, the crist

105 ial cells localized at the inner edge of the semicircular canals and to the ampullary and utricular w

106 r ear epithelium, including formation of the semicircular canals and, in some, development of sensory

107 nges in ventilation during engagement of the semicircular canals and/or the otolith organs were measu

108 The semicircular canals are biomechanical sensors responsibl

109 Because semicircular canals are normal in het mice, we conclude

110 s but also angular velocity signals from the semicircular canals are simultaneously used by the brain

111 in the nonsensory epithelium of the growing semicircular canals at embryonic day (E) 15.5.

112 sal fates such as the endolymphatic duct and semicircular canals by positively regulating genes such

113 Stimulation of the horizontal semicircular canals by yaw rotation increased minute ven

114 There are the typical three semicircular canals extending from the utricle, with the

115 k cristae within the ear, while in van gogh, semicircular canals fail to form altogether, resulting i

116 rom the dorsal otic vesicle within which the semicircular canals form.

117 owever, the endolymphatic fluid space in the semicircular canals is diminished and the roof of the am

118 In both cases the morphogenesis of the semicircular canals is disrupted.

119 nt adults, the endolymph-filled lumen of the semicircular canals is severely reduced.

120 es head rotations, which are detected by the semicircular canals of the inner ear.

121 elineated whether information from all three semicircular canals or just the horizontal canals, which

122 ons and the anatomy and firing properties of semicircular canals precisely predicted these perception

123 Preliminary studies indicate the semicircular canals provide a necessary component of the

124 ans are unloaded in microgravity, the fetus' semicircular canals receive high levels of stimulation d

125 Their enlarged semicircular canals reflect a highly refined organ of eq

126 The vestibular semicircular canals respond to angular acceleration that

127 ional rotation in the planes of the vertical semicircular canals revealed relative sparing of vertica

128 Furthermore, nonsensory structures such as semicircular canals seemed to display a greater suscepti

129 mp2 is strongly expressed in the prospective semicircular canals starting from the canal outpouch sta

130 vestibular crista, the sensory organ of the semicircular canals that sense head rotation.

131 n the inner ear, the otolith organs, and the semicircular canals transduce self-motion in an egocentr

132 cture of the inner ear, which contains three semicircular canals used to detect motion of the head in

133 When the semicircular canals were inactivated, horizontal eye mov

134 Rotations that excited the semicircular canals were much less effective in inducing

135 Among the nonsensory structures, the semicircular canals were the most sensitive and the endo

136 To assess the specific contributions of the semicircular canals without altering tonic VIIIth nerve

137 s constituent epithelial cells to form three semicircular canals, a central vestibule and a coiled co

138 or parts of the ear include three orthogonal semicircular canals, a central vestibule, a coiled cochl

139 nclude absence of the anterior and posterior semicircular canals, and a malformed saccule and cochlea

140 s in the inner ear, smaller SAGs, defects in semicircular canals, and abnormal neuromasts on the post

141 ape of the otic vesicle and formation of the semicircular canals, and define at least 20 complementat

142 lled diving Pan-Alcidae displayed compressed semicircular canals, and indistinct occipital sinuses an

143 erves, which innervate the otolithic organs, semicircular canals, and lateral lines, project to seven

144 of the vestibule and in the absence of three semicircular canals, anterior and posterior cristae.

145 , and dorsal otic derivatives, including the semicircular canals, endolymphatic duct and utricle, are

146 f the associated non-sensory components, the semicircular canals, in vertebrate inner ears.

147 nitially includes the sensory regions of the semicircular canals, known as the cristae ampullaris, bu

148 nd vestibulo-ocular reflexes mediated by the semicircular canals, little is known about the role of t

149 The vestibular apparatus, including three semicircular canals, saccule, utricle, and their associa

150 Among the three semicircular canals, the superior canal was the most sus

151 res found in the adult, including the mature semicircular canals, utricle, saccule, cochlear duct, en

152 ntation-independent rotation signal from the semicircular canals, which could be useful in compensati

153 mporally integrated rotation signal from the semicircular canals, which is critical for computing hea

154 ral malformation of the horizontal (lateral) semicircular canals.

155 rmation of their non-sensory components, the semicircular canals.

156 ective continual proliferative growth of the semicircular canals.

157 sule including the cartilage surrounding the semicircular canals.

158 y epithelium of the crista ampullaris of the semicircular canals.

159 ory ganglion, cochlea, saccule, utricle, and semicircular canals.

160 ures that house the sensory epithelia of the semicircular canals.

161 nd complete morphological development of the semicircular canals.

162 circling behaviour, due to reduced or absent semicircular canals.

163 sensory organs and restricted domains of the semicircular canals.

164 of the otocyst that is destined to form the semicircular canals.

165 to sample endolymph flow from both vertical semicircular canals.

166 olymphatic duct and the fusion plates of the semicircular canals.

167 e role of cell death in morphogenesis of the semicircular canals.

168 ecomes progressively restricted to the three semicircular canals.

169 otic vesicle shortly before formation of the semicircular canals.

170 at were separate from the projections of the semicircular canals.

171 r cells, and defects in the formation of the semicircular canals.

172 ivated by stimulation of the otoliths or the semicircular canals.

173 volving the superior, lateral, and posterior semicircular canals.

174 king and have severely truncated cochlea and semicircular canals.

175 nsgenic mice that lack functional horizontal semicircular canals.

176 vestibular endolymph that acts to stimulate semicircular canals.

177 signal requires contributions from multiple semicircular canals.

178 cular swimming, fused otoliths, and abnormal semicircular canals.

179 preparation that received inputs from intact semicircular canals.

180 nit, alpha1a.2, disrupted development of the semicircular canals.

181 ivities before and after inactivation of the semicircular canals.

182 ng from the vestibular rotation sensors, the semicircular canals.

183 d position using three orthogonally oriented semicircular canals; even slight changes in their shape

184 Here we report a new semicircular CCI (S-CCI) model by increasing the impact

185 includes the vestibular sensory patches and semicircular duct fusion plates, as well as in the adjac

186 The semicircular duct system is part of the sensory organ of

187 situ visualization and quantification of the semicircular duct system, using X-ray micro tomography a

188 phistication, but the biomechanics of actual semicircular duct systems has rarely been analyzed, fore

189 indicated by the lack of any distinguishable semicircular ducts, persistence of the primordial vestib

190 bidity of other therapeutic options, such as semicircular flap or shared eyelid flap procedures.

191 ite of DNA binding is comprised of a pair of semicircular grooves.

192 Transplantation of a semicircular, large-diameter hemi-DMEK graft.

193 nserts or loops that pack to form a concave, semicircular surface around the substrate leaving group.

194 magnetic impactor (Impactor One, MyNeuroLab; semicircular tip: 3mm radius; CCI tip diameter: 3mm).

195 e preoptic area, hypothalamus, optic tectum, semicircular torus, and caudal midbrain tegmentum, but c

196 ralaterally projecting axons grow in unusual semicircular trajectories, and the normal ipsilateral tu