ライフサイエンスコーパス: semicircular canal

1 sed by free-floating debris in the posterior semicircular canal.

2 chlea via virus injection into the posterior semicircular canal.

3 es of IK,L in type I hair cells of the mouse semicircular canal.

4 rmation of their non-sensory components, the semicircular canals.

5 ective continual proliferative growth of the semicircular canals.

6 sule including the cartilage surrounding the semicircular canals.

7 y epithelium of the crista ampullaris of the semicircular canals.

8 ory ganglion, cochlea, saccule, utricle, and semicircular canals.

9 ures that house the sensory epithelia of the semicircular canals.

10 nd complete morphological development of the semicircular canals.

11 circling behaviour, due to reduced or absent semicircular canals.

12 sensory organs and restricted domains of the semicircular canals.

13 of the otocyst that is destined to form the semicircular canals.

14 to sample endolymph flow from both vertical semicircular canals.

15 olymphatic duct and the fusion plates of the semicircular canals.

16 e role of cell death in morphogenesis of the semicircular canals.

17 ecomes progressively restricted to the three semicircular canals.

18 otic vesicle shortly before formation of the semicircular canals.

19 at were separate from the projections of the semicircular canals.

20 r cells, and defects in the formation of the semicircular canals.

21 ivated by stimulation of the otoliths or the semicircular canals.

22 volving the superior, lateral, and posterior semicircular canals.

23 king and have severely truncated cochlea and semicircular canals.

24 nsgenic mice that lack functional horizontal semicircular canals.

25 vestibular endolymph that acts to stimulate semicircular canals.

26 cular swimming, fused otoliths, and abnormal semicircular canals.

27 signal requires contributions from multiple semicircular canals.

28 preparation that received inputs from intact semicircular canals.

29 nit, alpha1a.2, disrupted development of the semicircular canals.

30 ivities before and after inactivation of the semicircular canals.

31 ng from the vestibular rotation sensors, the semicircular canals.

32 ral malformation of the horizontal (lateral) semicircular canals.

33 s constituent epithelial cells to form three semicircular canals, a central vestibule and a coiled co

34 or parts of the ear include three orthogonal semicircular canals, a central vestibule, a coiled cochl

35 d processes, superiorly positioned posterior semicircular canal, absence of a nuchal torus and a supr

36 We found that both irregular otolith and semicircular canal afferents, because of their higher se

37 onents arise from stimulation of otolith and semicircular canal afferents, respectively.

38 ON and TON receive principally utricular and semicircular canal afferents.

39 ent in the apex and all three cristae of the semicircular canal ampullae.

40 to account not only for the gain of a third semicircular canal and crista in gnathostomes, but also

41 However, formation of the lateral semicircular canal and its ampulla is usually unaffected

42 l computations underlying the integration of semicircular canal and otolith inputs required for accur

43 f afferent fibers innervating the individual semicircular canal and otolith organs was produced by se

44 alone, with most showing convergence between semicircular canal and otolith signals.

45 d by a smaller vestibular organ with thinner semicircular canals and a significant reduction in the n

46 bout the anteroposterior axis, with only two semicircular canals and a single sensory macula.

47 rns the shape of vestibular components - the semicircular canals and ampullae - by conferring anterop

48 vestibular hair cells in the cristae of the semicircular canals and auditory hair cells in the organ

49 development of the dorsolateral otocyst into semicircular canals and cristae through two distinct mec

50 hlear hypoplasia and complete absence of the semicircular canals and cristae.

51 st), otolith formation, morphogenesis of the semicircular canals and differentiation of the otic caps

52 x6 expression is seen throughout the forming semicircular canals and endolymphatic structures.

53 receptor, TrkB, lose all innervation to the semicircular canals and have reduced innervation of the

54 bsd homozygotes lack endolymphatic ducts and semicircular canals and have short cochlear ducts.

55 g-eared mutants show abnormal development of semicircular canals and lack cristae within the ear, whi

56 for complicated stimuli, which activated the semicircular canals and otolith organs and involved both

57 in the vestibular system, which includes the semicircular canals and otolith organs.

58 ibular receptors consist of highly conserved semicircular canals and otolith organs.

59 y reflect the stimulus magnitudes handled by semicircular canals and otolith organs.

60 Signals from the receptors, the semicircular canals and otoliths, are carried by the eig

61 ll simultaneously stimulate receptors in the semicircular canals and otoliths.

62 sive loss of all afferent innervation to the semicircular canals and reduced innervation to the utric

63 , at larval stages zebrafish lack functional semicircular canals and rely exclusively on their otolit

64 In young subjects, natural engagement of the semicircular canals and the otolith organs by head rotat

65 regulator, is required for the formation of semicircular canals and their associated sensory cristae

66 ect angular head movements lies in the three semicircular canals and their sensory tissues, the crist

67 ial cells localized at the inner edge of the semicircular canals and to the ampullary and utricular w

68 r ear epithelium, including formation of the semicircular canals and, in some, development of sensory

69 nges in ventilation during engagement of the semicircular canals and/or the otolith organs were measu

70 Otolithic, semicircular canal, and anterior lateral line nerves all

71 nclude absence of the anterior and posterior semicircular canals, and a malformed saccule and cochlea

72 s in the inner ear, smaller SAGs, defects in semicircular canals, and abnormal neuromasts on the post

73 ape of the otic vesicle and formation of the semicircular canals, and define at least 20 complementat

74 lled diving Pan-Alcidae displayed compressed semicircular canals, and indistinct occipital sinuses an

75 erves, which innervate the otolithic organs, semicircular canals, and lateral lines, project to seven

76 of the vestibule and in the absence of three semicircular canals, anterior and posterior cristae.

77 The semicircular canals are biomechanical sensors responsibl

78 Because semicircular canals are normal in het mice, we conclude

79 s but also angular velocity signals from the semicircular canals are simultaneously used by the brain

80 in the nonsensory epithelium of the growing semicircular canals at embryonic day (E) 15.5.

81 l, fore-aft, vertical) for CSs and along the semicircular canal axes for SSs.

82 ursuit preferred-direction vectors along the semicircular canal axes was observed, the sensitivity of

83 sal fates such as the endolymphatic duct and semicircular canals by positively regulating genes such

84 Stimulation of the horizontal semicircular canals by yaw rotation increased minute ven

85 volving the superior, lateral, and posterior semicircular canal can have different etiologies, includ

86 The present results show that the semicircular canal crista ampullaris of the toadfish, Op

87 ricle, and a complete loss of the horizontal semicircular canal crista, as well as a fusion of the ut

88 es the peripheral zones of each of the three semicircular canal cristae.

89 This force pushes on the semicircular canal cupula, leading to nystagmus.

90 s Chd7 deficiency have circling behavior and semicircular canal defects and are an excellent animal m

91 Posterior semicircular canal dehiscence is a rare entity, with sim

92 Superior semicircular canal dehiscence is now a well-established

93 Lateral semicircular canal dehiscence is usually associated with

94 The main focus will be on superior semicircular canal dehiscence.

95 by showing that the retinoic acid effect on semicircular canal development can be overcome by exogen

96 acent to the BMP4 cell foci prevented normal semicircular canal development.

97 del accounts for observed axis tilt based on semicircular canal directional sensitivity and response

98 In zebrafish and Xenopus, semicircular canal ducts develop when projections of epi

99 Morphogenesis of the semicircular canal ducts in the vertebrate inner ear is

100 asia, and ear defects including deafness and semicircular canal dysgenesis.

101 , and dorsal otic derivatives, including the semicircular canals, endolymphatic duct and utricle, are

102 In generating a semicircular canal, epithelial cells seem to 'disappear'

103 d position using three orthogonally oriented semicircular canals; even slight changes in their shape

104 There are the typical three semicircular canals extending from the utricle, with the

105 k cristae within the ear, while in van gogh, semicircular canals fail to form altogether, resulting i

106 rom the dorsal otic vesicle within which the semicircular canals form.

107 hour intervals during the critical stages of semicircular canal formation (E6-E7).

108 The defect in semicircular canal formation is due to problems in the i

109 BMP4 antagonists disrupt semicircular canal formation, as does exposure to retino

110 survival in the ear, for HC differentiation, semicircular canal formation, statoacoustic ganglion (SA

111 and disrupted hair cell differentiation and semicircular canal formation.

112 pment, Nor-1 is expressed exclusively in the semicircular canal forming fusion plates.

113 Semicircular canal geometries underwent distinct changes

114 Here we show that semicircular canal hair cells generate a mechanical nonl

115 We imaged the horizontal semicircular canal (HSCC) crista and cupula of toadfish,

116 f the associated non-sensory components, the semicircular canals, in vertebrate inner ears.

117 ing activity after canal occlusions, but the semicircular canal input is critical for updating the ne

118 eives highly overlapping otolithic organ and semicircular canal input, and we propose that this regio

119 and the horizontal plane to determine their semicircular canal input.

120 d ventral MgON) receive mainly utricular and semicircular canal inputs, suggesting vestibular roles.

121 owever, the endolymphatic fluid space in the semicircular canals is diminished and the roof of the am

122 In both cases the morphogenesis of the semicircular canals is disrupted.

123 nt adults, the endolymph-filled lumen of the semicircular canals is severely reduced.

124 nitially includes the sensory regions of the semicircular canals, known as the cristae ampullaris, bu

125 -/- mutants showed an absence of the lateral semicircular canal, lateral ampulla, utriculosaccular du

126 nd vestibulo-ocular reflexes mediated by the semicircular canals, little is known about the role of t

127 ay variable asymmetric lateral and posterior semicircular canal malformations, as well as defects in

128 and nuchal torus) and temporal labyrinthine (semicircular canal) morphology with the Neandertals.

129 The horizontal semicircular canal nerve of the toadfish, Opsanus tau, w

130 Each semicircular canal nerve projects to distinct regions of

131 eling the peripheral axons of the horizontal semicircular canal nerve with biocytin after nerve regro

132 Semicircular canal nerves project primarily to ventral r

133 egregated projections from all otolithic and semicircular canal nerves, whereas the ventral DON and T

134 re recorded from chinchillas after bilateral semicircular canal occlusion.

135 Ocular motor, semicircular canal-ocular, and semicircular canal-otolit

136 bers and varicosities were visualized in the semicircular canal of red-eared turtles (Trachemys scrip

137 behaviour due to truncations of the lateral semicircular canal of the inner ear.

138 es head rotations, which are detected by the semicircular canals of the inner ear.

139 elineated whether information from all three semicircular canals or just the horizontal canals, which

140 Ocular motor, semicircular canal-ocular, and semicircular canal-otolith interaction assessments sugge

141 ing focused on the otolith-ocular reflex and semicircular canal-otolith interaction.

142 lectrode placement with respect to bilateral semicircular canal pairs or alterations of the bipolar s

143 utgrowth and a failure of fusion to form the semicircular canal pillars.

144 ons and the anatomy and firing properties of semicircular canals precisely predicted these perception

145 lysis revealed smaller posterior and lateral semicircular canal primordia and a delay in the canal fu

146 While there is considerable evidence that a semicircular canal prosthesis that senses angular head v

147 Preliminary studies indicate the semicircular canals provide a necessary component of the

148 ans are unloaded in microgravity, the fetus' semicircular canals receive high levels of stimulation d

149 Their enlarged semicircular canals reflect a highly refined organ of eq

150 The vestibular semicircular canals respond to angular acceleration that

151 ional rotation in the planes of the vertical semicircular canals revealed relative sparing of vertica

152 The vestibular apparatus, including three semicircular canals, saccule, utricle, and their associa

153 Furthermore, nonsensory structures such as semicircular canals seemed to display a greater suscepti

154 ad significantly greater horizontal-vertical semicircular canal signal convergence than did neurons n

155 ess or near target viewing demonstrated that semicircular canal signals are necessary sensory cues fo

156 It is traditionally believed that semicircular canal signals drive compensatory responses

157 y storage network is to temporally integrate semicircular canal signals, so that they may be used to

158 morphogenetic program that shapes the three semicircular canals (SSCs) must be executed with extreme

159 mp2 is strongly expressed in the prospective semicircular canals starting from the canal outpouch sta

160 ze that the unparalleled modification of the semicircular canal system represented a key 'point of no

161 an independent perspective by looking at the semicircular canal system, one of the main sense organs

162 r nuclei that overlapped with the horizontal semicircular canal terminal fields, whereas saccular aff

163 vestibular crista, the sensory organ of the semicircular canals that sense head rotation.

164 Among the three semicircular canals, the superior canal was the most sus

165 n the inner ear, the otolith organs, and the semicircular canals transduce self-motion in an egocentr

166 that stimulated both the otolith organs and semicircular canals (upright roll and on tail yaw) produ

167 cture of the inner ear, which contains three semicircular canals used to detect motion of the head in

168 res found in the adult, including the mature semicircular canals, utricle, saccule, cochlear duct, en

169 Contributions of semicircular canal versus otolith organ signals were inv

170 tegy that markedly differs from that used by semicircular canal vestibular afferents to encode rotati

171 of physiologically characterized horizontal semicircular canal vestibular nerve afferents in the toa

172 are usually attributed to the dysfunction of semicircular canal vestibulo-ocular reflexes, as they ha

173 When the semicircular canals were inactivated, horizontal eye mov

174 Rotations that excited the semicircular canals were much less effective in inducing

175 Among the nonsensory structures, the semicircular canals were the most sensitive and the endo

176 ntation-independent rotation signal from the semicircular canals, which could be useful in compensati

177 mporally integrated rotation signal from the semicircular canals, which is critical for computing hea

178 To assess the specific contributions of the semicircular canals without altering tonic VIIIth nerve