ライフサイエンスコーパス: seminiferous tubule

1 n Leydig cells (somatic cells outside of the seminiferous tubules).

2 is in the fluctuating environment within the seminiferous tubule.

3 re elongate spermatids into the lumen of the seminiferous tubule.

4 questered behind the Sertoli cell barrier in seminiferous tubules.

5 storage vesicles within Sertoli cells of the seminiferous tubules.

6 stmeiotic round spermatid compartment of the seminiferous tubules.

7 permatocytes in the basal compartment of the seminiferous tubules.

8 rized by calcifications within the lumina of seminiferous tubules.

9 in the kidney collecting tubules and testis seminiferous tubules.

10 g, oviduct, epididymis, ductus deferens, and seminiferous tubules.

11 erstitial tissue that normally surrounds the seminiferous tubules.

12 aled that UT3 is located in Sertoli cells of seminiferous tubules.

13 ble to generate spermatogenesis in recipient seminiferous tubules.

14 creased mitotic index and disorganization of seminiferous tubules.

15 ring formation of structures resembling male seminiferous tubules.

16 , which are however found in the wall of the seminiferous tubules.

17 a PEDF, may prevent vascularization of human seminiferous tubules.

18 d18 foci were increased in the lumina of the seminiferous tubules.

19 r for the identification of Sertoli cells in seminiferous tubules.

20 ecifically in the nuclei of Sertoli cells in seminiferous tubules.

21 study mechanisms of virus persistence in the seminiferous tubules.

22 es, which in turn are composed of convoluted seminiferous tubules.

23 icle-stimulating hormone receptor within the seminiferous tubules.

24 ce of active spermatogenesis in 24 +/- 7% of seminiferous tubules.

25 oimaging, and in situ confocal microscopy of seminiferous tubules.

26 n of germ cells localized at the base of the seminiferous tubules.

27 ressed primarily in Sertoli cells within the seminiferous tubules.

28 Both radionuclides gained access to the seminiferous tubules.

29 sulting in cell death and destruction of the seminiferous tubules.

30 testicular size and no spermatozoa in their seminiferous tubules.

31 reduced sperm counts, and disruption of the seminiferous tubules.

32 within the thin vascular layer overlying the seminiferous tubules.

33 als, including human, can replicate in mouse seminiferous tubules after transplantation, the growth f

34 IKV to establish persistent infection in the seminiferous tubules, an immune-privileged site in the t

35 lls migrated to the basement membrane of the seminiferous tubule and were maintained similar to SSCs.

36 rm counts and a high frequency of degenerate seminiferous tubules and abnormal sperm.

37 Testes from PTU-treated male tadpoles had seminiferous tubules and advanced stage male germ cells,

38 the establishment of the avascular nature of seminiferous tubules and after puberty androgens may fur

39 stem cells reside in specific niches within seminiferous tubules and continuously generate different

40 were evident in light micrographs of testis' seminiferous tubules and epithelial cells lining the epi

41 e when administered intratesticularly enters seminiferous tubules and exerts effects beyond BTB is cu

42 PAC1R(3a) mRNA is preferentially detected in seminiferous tubules and is expressed at the highest lev

43 ar space, creating a microenvironment within seminiferous tubules and providing immune privilege to m

44 fertile and sired offspring but had abnormal seminiferous tubules and reduced sperm counts.

45 the testes of adult males showed dilation of seminiferous tubules and reduction in their density when

46 nockout resulted in disruption of developing seminiferous tubules and subsequent progressive loss of

47 , almost all Sertoli cells are lost from the seminiferous tubules and the Leydig cell population is r

48 scent protein (GFP) transgenic mice into the seminiferous tubules and the testicular interstitium of

49 ased apoptotic cells within the walls of the seminiferous tubules, and a decrease in the number, moti

50 Treatment of mice with JQ1 reduced seminiferous tubule area, testis size, and spermatozoa n

51 ules were approximated by a cross-section of seminiferous tubules arranged in a hexagonal pattern, wi

52 Rat seminiferous tubules at stages I, II-III, IV-V, VI, VIIa

53 Focal seminiferous tubule atrophy accompanied by Leydig cell h

54 Seminiferous tubule basement membrane (STBM) plays an im

55 , we observed a lower mutation frequency for seminiferous tubule cell preparations, which contain all

56 tion studies, non-selected, freshly isolated seminiferous tubule cells were transferred to the testis

57 ically significant decrease in the number of seminiferous tubules containing germ cells.

58 In isolated 7 days postpartum seminiferous tubules containing mostly germ line stem ce

59 c expression of I-CREBs in germ cells of the seminiferous tubules correlates with the cyclical down-r

60 optosis of germ cells, spermatogenic arrest, seminiferous tubule degeneration, and infertility.

61 ce have excessive spermatocyte apoptosis and seminiferous tubule degeneration.

62 tion, there was some impairment of renal and seminiferous tubule development.

63 ertile by 3 mo of age and eventually exhibit seminiferous tubules devoid of germ cells.

64 ndrogen effects, such as testicular atrophy, seminiferous tubule diameter reduction and hyperplasia o

65 ter testicular atrophy and decreased average seminiferous tubule diameter when compared with K48R-age

66 ls and hyperplastic Leydig cells, leading to seminiferous tubule dilation and degeneration of germ ce

67 animals produces sexual hormone dysfunction, seminiferous tubule dystrophy and spermatogenesis blocka

68 ired in PTM-ARKO males, indicated by reduced seminiferous tubule fluid production and reduced express

69 from the basal to apical compartments of the seminiferous tubules for further development and maturat

70 h spermatozoa formation in 13% to 17% of the seminiferous tubules formed in the grafts.

71 Rfx2-null round spermatids detached from the seminiferous tubules, forming large multinucleated giant

72 ed by GFP fluorescence in squashes of living seminiferous tubules from adult testes, and the presence

73 hese pathological responses are conserved in seminiferous tubules from Gravin(-/-) mice where an over

74 tis displayed typical signs of aging (patchy seminiferous tubules, germ cell depletion, and vacuoliza

75 males are infertile and the analysis of the seminiferous tubules identified disrupted acrosomal deve

76 n of germ cells in a substantial fraction of seminiferous tubules in aged mice.

77 e adult testis and to a lesser degree in the seminiferous tubules in spermatogonia and Sertoli cells.

78 tis barrier showed increased permeability of seminiferous tubules in the Arid4a(-/-)Arid4b(+/-) teste

79 ial for the maintenance of Sertoli cells and seminiferous tubules in the developing testes.

80 d mild interstitial edema and closely packed seminiferous tubules in the left testes, indicating reve

81 Histological analysis of seminiferous tubules in the testes, caput and corpus epi

82 tive dysfunction associated with hypoplastic seminiferous tubules in the testis and perturbed corpus

83 ced testis size and numbers of germ cells in seminiferous tubules, increased germ cell apoptosis, and

84 Here we show that cells from adult seminiferous tubules interact with mammary epithelial ce

85 lls, which are an important component of the seminiferous tubules, is robust and induces a strong ant

86 showed hypoplastic and dysgenic testes, with seminiferous tubules lacking spermatogonia.

87 decreased number of germ cells, degenerating seminiferous tubules, maturation arrest and apoptosis, i

88 ermatids, and the bicarbonate present in the seminiferous tubule may be a signal that regulates cAMP

89 m cells caused their premature exit from the seminiferous tubule niche, resulting in germ cell deplet

90 In the seminiferous tubules of busulfan-treated mice, GFP-posit

91 Consistent with enhanced apoptosis in seminiferous tubules of C/C testes, we recorded a drasti

92 of undifferentiated iPSCs directly into the seminiferous tubules of germ cell-depleted immunodeficie

93 spermatogenesis was totally compromised, as seminiferous tubules of homozygous mutant animals were d

94 , identifiable mutations directly within the seminiferous tubules of human testes.

95 at clump-forming rabbit germ cells colonized seminiferous tubules of immunodeficient mice, proliferat

96 8(Ink4c) and p19(Ink4d) are expressed in the seminiferous tubules of postnatal wild-type mice, being

97 hest level of expression was detected in the seminiferous tubules of testis.

98 nor cells established spermatogenesis in the seminiferous tubules of the host, and normal spermatozoa

99 genesis takes place in the epithelium of the seminiferous tubules of the testes, producing millions o

100 on becomes XY-specific and restricted to the seminiferous tubules of the testis as gonadogenesis proc

101 ransdifferentiation to structures resembling seminiferous tubules of the testis, including Sertoli-li

102 larin family, is expressed at high levels in seminiferous tubules of the testis, specifically in Sert

103 on spermatogenesis, which takes place in the seminiferous tubules of the testis.

104 ed mainly by spermatocytes and spermatids in seminiferous tubules of the testis.

105 d that both mRNAs were strongly expressed in seminiferous tubules of the testis.

106 However, this was not found in the seminiferous tubules of W/W(v) mice.

107 not DeltaNp73KO mice, display a "near-empty seminiferous tubule" phenotype due to massive premature

108 s of cells: (i) epithelial germ cells of the seminiferous tubules, primarily spermatids and spermatoc

109 s while OSKM cells that remained outside the seminiferous tubule proliferated extensively and formed

110 e Sertoli cell, the only somatic cell within seminiferous tubules, provides the stem cell niche throu

111 how impaired testis development, degenerated seminiferous tubules, reduced sperm count and low fertil

112 tis and mechanisms by which the virus enters seminiferous tubules remain unclear.

113 are small, compared with the diameter of the seminiferous tubules, resulting in high energy depositio

114 was small, compared with the diameter of the seminiferous tubules, resulting in high energy depositio

115 More detailed analysis of specific cells in seminiferous tubules shows localization of Atr to the nu

116 Seminiferous tubule staging shows that stages X to XII,

117 UB1 is involved in cellular functions in the seminiferous tubules such as spermatogenesis.

118 expressed in both the podocyte and the basal seminiferous tubule, suggesting that the loss of CD2AP i

119 sues only in the developing spermatocytes of seminiferous tubules, suggesting that mSgy is a spermato

120 meiotic spermatids are the only cells of the seminiferous tubules that express HIP1.

121 n the Sertoli-Sertoli tight junctions in the seminiferous tubules, the approximately 32 kDa murine JA

122 iremia, ZIKV must establish infection in the seminiferous tubules, the site of spermatozoon developme

123 l stem cells from other species to the mouse seminiferous tubule to generate spermatogenesis.

124 Focal vacuolization in some of the seminiferous tubules was observed in 4-week-old mutant t

125 The seminiferous tubules were divided into concentric layers

126 Adult testicular cells, isolated from seminiferous tubules, were mixed with limiting dilutions

127 testis and was localized to a region of the seminiferous tubule where secondary spermatocytes and ea

128 eir radial migration to the periphery of the seminiferous tubule where the spermatogenic niche will f

129 uptake into the testis as a whole and to the seminiferous tubules where the germ cells are located.

130 ed that the testes were composed of atrophic seminiferous tubules, whereas germ cells were found in 1

131 The testis cords give rise to the adult seminiferous tubules, whereas steroidogenic Leydig cells

132 n culminates in complete degeneration of the seminiferous tubules, which become acellular, empty spac

133 unostaining for Mamu-AG5 in cells within the seminiferous tubules, which was corroborated by localiza

134 is normally provided by Sertoli cells of the seminiferous tubules, whose function depends on testoste

135 roliferate and migrate within the developing seminiferous tubule, with proper niche interaction and m