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1 sults in the translation of UAG in vivo as a sense codon.
2 rokaryotes, which involves reassignment of a sense codon.
3 cognize the stop codons UAG and UAA, and ten sense codons.
4 plement, thereby orthogonalizing some of the sense codons.
5 ipts, there was no preference for CAG or UCG sense codons.
6 to efficiently discriminate between stop and sense codons.
7 tants with ribosomes programmed with stop or sense codons.
8 termination, serve an alternate function as sense codons.
9 ility of synthetic tRNAs to decode all of 61 sense codons.
10 via "recoding" of UGA from a stop codon to a sense codon, a process that requires specific secondary
12 Replacing the tnaC UGA stop codon with a sense codon allows considerable expression, which is als
14 arly all cases, the amber codon is used as a sense codon, and an orthogonal tRNA/aminoacyl-tRNA synth
16 eporters was constructed with nearly all the sense codons as the "takeoff site", each with its matche
18 this process, the stop codon is decoded as a sense codon by a near-cognate tRNA, which programs the r
20 ow that several adjacent, arbitrarily chosen sense codons can be completely reassigned to various unn
21 ially enables the reassignment of at least 9 sense codons coding for Ser, Arg, Leu, Pro, Thr, and Gly
22 alanine and cysteine in response to stop and sense codons, depending on the identity element and anti
23 RF1 for ribosomes programmed with different sense codons does not correlate with the defects in pept
35 etic recoding of genomes, to remove targeted sense codons, may facilitate the encoded cellular synthe
37 hanism of paromomycin inhibition on stop and sense codons, paired with correlated structural changes
38 of the UAG stop codon; however, reassigning sense codons poses a greater challenge because such codo
40 aking the degeneracy of the genetic code via sense codon reassignment has emerged as a way to incorpo
43 m the sup45-2 strain do not show a defect in sense-codon translation at the non-permissive temperatur
44 mechanism of discrimination between stop and sense codons, we developed a new, pre-steady state kinet
45 hether A-site nuclease activity also cleaves sense codons, we induced ribosome pausing at each of the
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