ライフサイエンスコーパス: sensitive period

1 ime that pups first begin to leave the nest (sensitive period).

2 major depressive disorder (MDD) during this sensitive period.

3 tors with whom they interact during an early sensitive period.

4 odor learning circuit characteristic of the sensitive period.

5 atal Day 8) and after (Postnatal Day 12) the sensitive period.

6 E release associated with termination of the sensitive period.

7 perience during a developmentally restricted sensitive period.

8 uditory space map was restricted to an early sensitive period.

9 posed to gonadal hormones during a perinatal sensitive period.

10 tagmus-induced visual deprivation during the sensitive period.

11 , is dependent on experience and linked to a sensitive period.

12 time course of pendular nystagmus during the sensitive period.

13 characterize the timing and duration of this sensitive period.

14 early phase, appearing slightly later in the sensitive period.

15 ence and is often enhanced during a juvenile sensitive period.

16 by imitating a tutor song during a juvenile sensitive period.

17 lishing synaptic patterning during perinatal sensitive periods.

18 s and requires sensory input during distinct sensitive periods.

19 privation coincides with early developmental sensitive periods.

20 abitat and (3) alteration of activity during sensitive periods.

21 ed by complex sounds in a series of distinct sensitive periods.

22 d to artemisinin exposures during the embryo sensitive period (6-12 wk gestation) were as follows: aH

23 behaviors, and (3) a dopamine- and serotonin-sensitive period affecting aggression, impulsivity and b

24 Dark-rearing, which prolongs the sensitive period, also prolongs the expression of the Ca

25 s focused on animals prior to the end of the sensitive period and did not examine the visual cortex s

26 both the biology of the brain's postischemic sensitive period and the difficult question of what kind

27 irds must hear the sounds of adults during a sensitive period, and must hear their own voice while le

28 earning and the restriction of learning to a sensitive period, and what factors explain the highly se

29 mpact of temperature variation during thermo-sensitive periods (anthesis and grain-filling; TSP) of w

30 While allowing for adaptation, such sensitive periods are also vulnerability windows during

31 in intake, especially during developmentally sensitive periods, are poorly understood.

32 b) adrenalectomy developmentally extends the sensitive period as indicated by odor-shock-induced odor

33 We test the hypothesis that adolescence is a sensitive period because of the active development of co

34 ans are an excellent model for investigating sensitive periods because training starts early and can

35 del system, we discovered the existence of a sensitive period, before 4 mo, when exposure determines

36 fluenced by environmental experience during "sensitive periods," before onset of behavioral function.

37 ure-sensitive apx-1 mutant has a temperature-sensitive period between the 4-cell and 8-cell stages.

38 e we investigated neural correlates of these sensitive periods by assessing developmental changes in

39 ehaviorally and neurophysiologically defined sensitive periods by taking into account differences in

40 Abnormal visual experience during the sensitive period can lead to amblyopia, a developmental

41 Environmental insults during sensitive periods can affect hippocampal development and

42 nist use between the 2-month embryologically sensitive period (case window) and the 2 months precedin

43 period slices reverts synaptic plasticity to sensitive period characteristics.

44 Although sensitive-period control paired odor-shock pups learned

45 prevented by transcription blockers, with a sensitive period corresponding to the period of activity

46 who were exposed to thalidomide early in the sensitive period (days 20 to 26+/-).

47 The results suggest that sensitive period deficits in fear conditioning may be re

48 for social interaction, and we propose that sensitive-period disruption of such internal brain commu

49 ion, but conclude that better delineation of sensitive periods, dose-response relationships, and long

50 his suggests maternal care quality may alter sensitive-period duration.

51 The effects on NH4Cl preference reflect a sensitive period during development because adult rats r

52 Thus, P2-21 is a sensitive period during which 5-HT modulates adult anxie

53 ty/depression-like behavior, and P22-41 is a sensitive period during which DA and 5-HT bi-directional

54 They also reveal an early-life sensitive period during which trkB-ERK42/44 tone determi

55 The auditory cortex has sensitive periods during which it is maximally receptive

56 Development passes through sensitive periods, during which plasticity allows for ge

57 These findings may indicate a sensitive period early in life for acquiring rhythm in p

58 esting-state connectivity, consistent with a sensitive period ending with adolescence for the amygdal

59 In the rat the sensitive period ends sometime after postnatal day 50 (P

60 second decade of life, possibly reflecting a sensitive period for adapting to one's social environmen

61 s during the gastrula stage, which is the RA-sensitive period for anterior/posterior (A/P) patterning

62 ge at implant beyond 2.5 years, suggesting a sensitive period for bimodal integration in speech perce

63 The most stress-sensitive period for cngc16 pollen was during germinatio

64 on Pet-1, thus revealing an early postnatal sensitive period for control of 5-HT excitability genes.

65 from caregivers cues the termination of the sensitive period for environmental input into emotion ne

66 deprivation is delayed until P30, after the sensitive period for experience-dependent changes in bul

67 ry brainstem during development and during a sensitive period for ipsilateral sprouting, so we hypoth

68 Rs), we studied the relationship between the sensitive period for monocular deprivation and the expre

69 t of glutamate receptors correlates with the sensitive period for monocular deprivation in the visual

70 early postnatal development may represent a sensitive period for race perception.

71 Neonates have a sensitive period for rapid, robust odor learning charact

72 e transformed into motor gestures during the sensitive period for song learning.

73 isition of a normal vocal pattern during the sensitive period for song learning.

74 nd undergo large-scale retraction during the sensitive period for song learning.

75 sing them to loud white noise throughout the sensitive period for song learning.

76 n death in young birds that are entering the sensitive period for song learning.

77 hese results may reflect that childhood is a sensitive period for telomere attrition.

78 Here we show that adolescence is a sensitive period for the emergence of prefrontal cogniti

79 at the periadolescent transition is indeed a sensitive period for the functional maturation of prefro

80 y adolescence and suggest an early childhood sensitive period for these effects.

81 We conclude that there is a sensitive period for visual specialization in MT/MST.

82 these circuits are adult-like throughout the sensitive period for vocal learning and remain stable de

83 n DLM axon arbors occur at the height of the sensitive period for vocal learning, and hence may repre

84 ely important for song production during the sensitive period for vocal learning, and the overall siz

85 Adolescence is a sensitive period for weight gain and risky health behavi

86 hese findings provide important clues to how sensitive periods for auditory feedback and vocal plasti

87 Moreover, sensitive periods for changes in individual pathways are

88 to examine the neural mechanisms regulating sensitive periods for learning.

89 te that the timing and even the existence of sensitive periods for plasticity of a neural circuit and

90 downregulates sharply prior to the onset of sensitive periods for plasticity, yet the functional imp

91 nce and that spine turnover increases during sensitive periods for sensory map formation.

92 Previous studies have identified sensitive periods for the developing barn owl during whi

93 evelopmental trajectories, whether there are sensitive periods for these effects, as well as whether

94 ased gene expression in the post-temperature sensitive period gonads.

95 rly institutionalization, suggest a possible sensitive period in cognitive development, and underscor

96 Training during a sensitive period in development may have greater effects

97 lacks Met transcript during the insecticide-sensitive period in development.

98 tively, providing experimental evidence of a sensitive period in humans during which the environment

99 ning task is consistent with the notion of a sensitive period in language learning: Children show bet

100 To test for a sensitive period in MT/MST development, we used fMRI to

101 al studies indicate that fetal life may be a sensitive period in relation to bone growth and minerali

102 asticity that has been documented during the sensitive period in young children and animals leaves th

103 c variation and environmental insults during sensitive periods in brain development have long-term co

104 study of optimal environmental input during sensitive periods in brain development.

105 re access to bilateral auditory input during sensitive periods in human development.

106 n shown to alter neural plasticity and shift sensitive periods in perceptual development.

107 pend on experiential factors during specific sensitive periods in the animal's development.

108 mPFC-BLA transmission and point to potential sensitive periods in the development of this critical ne

109 lopment through focused interventions during sensitive periods in their maturation.

110 The sensitive period is a special time for auditory learning

111 d capacity for behavioural learning during a sensitive period is associated with enhanced spine dynam

112 This sensitive period is coincident with low endogenous corti

113 Findings suggest a sensitive period leading to lasting alterations in somat

114 ral circuits are remodeled during restricted sensitive periods, leading to the emergence of precise p

115 ized that low corticosterone levels modulate sensitive-period learning.

116 Visual deprivation during a developmental sensitive period markedly alters visual cortical respons

117 ment, which impacts adult behavior, but 5-HT-sensitive periods, neural substrates, and behavioral con

118 Infant rats exhibit sensitive-period odor learning characterized by olfactor

119 ation modulates olfactory bulb correlates of sensitive-period odor learning in a manner consistent wi

120 how that (a) exogenous CORT prematurely ends sensitive-period odor-shock-induced preferences; (b) adr

121 cocaine exposure during the developmentally sensitive period of adolescence.

122 dicate that administration of SSRIs during a sensitive period of brain development results in long-la

123 decreased amygdala Mecp2 expression during a sensitive period of brain sexual differentiation disrupt

124 ic variation in parental presence during the sensitive period of childhood affects the recruitment of

125 Exposure to adversity in utero at a sensitive period of development can bring about physiolo

126 tata) learn a specific song pattern during a sensitive period of development, after which song change

127 t environmental fluctuations during the most sensitive period of development, allowing coherent adapt

128 harmacological receptor antagonists during a sensitive period of development.

129 transiently inactivating VH in rats during a sensitive period of development.

130 erall, these data support the existence of a sensitive period of early gestation when epigenetic prog

131 whereby a stimulus or insult at a critical, sensitive period of early life has permanent effects on

132 erience of a particular temperature during a sensitive period of embryogenesis sculpts not only the p

133 pse stability and suggest the existence of a sensitive period of heightened hippocampal plasticity in

134 perimenopausal brain are characterized by a sensitive period of hormone responsiveness, and in both

135 ve, IGF-II needs to be administered within a sensitive period of memory consolidation.

136 Exploiting this sensitive period of neural development, we modified exis

137 impairment is attributable to a short-lived sensitive period of postischemic plasticity defined by u

138 The temperature-sensitive period of rpm-1 coincides with the time of syn

139 rces the view that pregnancy may be the most sensitive period of the life cycle in which nutritional

140 The temperature-sensitive period of the mutant is during early embryogen

141 with the deprivation experienced during the sensitive period of visual development.

142 Refinement of topographic maps during sensitive periods of development is a characteristic fea

143 f BLA neurons, and many more have identified sensitive periods of emotional maturation.

144 was either disabled or an infant, suggesting sensitive periods of exposure.

145 f pathogen ecology can be leveraged to align sensitive periods of gestation with the low-transmission

146 c maturational stages, neural circuits enter sensitive periods of heightened plasticity, during which

147 This thalamic sensitive period overlaps temporally with experience-dep

148 Odor was paired with 0.5 mA shock in either sensitive-period (P8) or postsensitive-period (P12) pups

149 he initiation, closure, and reinstatement of sensitive period plasticity has emerged from extensive r

150 eriod pups, but no significant plasticity in sensitive period pups incapable of learning odor aversio

151 ficant long-term synaptic plasticity in post-sensitive period pups, but no significant plasticity in

152 has taught us valuable information regarding sensitive periods, rearrangement of synaptic connections

153 We draw upon the model of sensitive period regulation within the visual system, an

154 ent by diazepam in BTBR mice during an early sensitive period rescued inhibition and integration in t

155 of central nervous system development, such sensitive periods shape the formation of neurocircuits t

156 oline's effect on EI suggests that potential sensitive periods should be considered in future work.

157 learning in the zebra finch occurs during a sensitive period similar to that for human speech.

158 GABA(A) receptor blockade in post-sensitive period slices reverts synaptic plasticity to s

159 y brain-derived neurotrophic factor during a sensitive period soon after these neurons reach destinat

160 During a perinatal sensitive period, steroid hormones, in particular estrad

161 rather than olfactory bulb changes underlie sensitive period termination.

162 sults suggest corticosterone is important in sensitive-period termination and developmental emergence

163 Because sensitive-period termination coincides with a declining

164 d, we explored the role of corticosterone in sensitive-period termination.

165 steroid hormone exposure during a perinatal sensitive period that alters subsequent hormonal and non

166 utations broadly disrupted a developmentally sensitive period that corresponded to the period of heig

167 sensory system development, (2) a serotonin-sensitive period that impacts cognition, anxiety- and de

168 Specifically, we review (1) a serotonin-sensitive period that impacts sensory system development

169 Such knowledge of sensitive periods that determine the developmental traje

170 l mechanism by which estradiol acts during a sensitive period to establish a profound and lasting sex

171 on temperature during a critical temperature sensitive period (TSP) determines sexual fate of the ind

172 uggest that therapeutic interventions during sensitive periods, typically before the onset of clear n

173 ty, and find ways to augment and prolong the sensitive period using pharmacological agents or noninva

174 pendular nystagmus during each decile of the sensitive period was associated with an additional 0.022

175 Adolescence in human males is a hormonally sensitive period when many adult behaviors develop, incl

176 ene expression patterns during the perinatal sensitive period, when organizational gonadal hormones e

177 Data support a possible sensitive period where functional connections between co

178 ical findings may reflect the existence of a sensitive period where the functional connections betwee

179 action of ORC axons and glial cells within a sensitive period, whereas targeting of ORC axons appears

180 dings provide evidence for a developmentally sensitive period whereby subcortical structures in young

181 t into gene function and identifies critical sensitive periods whereby genetic factors may influence