ライフサイエンスコーパス: sensory organ

1 te for Merkel cell/neurite complexes in this sensory organ.

2 preclude analysis at the level of an entire sensory organ.

3 ing pathways may specify this highly derived sensory organ.

4 pes of air particle movements using a common sensory organ.

5 sues, including the skin, the body's largest sensory organ.

6 generates different cell types of the mature sensory organ.

7 rk that controls the development of a simple sensory organ.

8 namic turnover of cells in this regenerating sensory organ.

9 stitute the cellular components of the adult sensory organ.

10 or morphology of cells of the adult external sensory organ.

11 egion, leading to animals lacking the apical sensory organ.

12 we did not recognize any oral multicellular sensory organ.

13 tle patterns, and in the positioning of some sensory organs.

14 Perception involves motor control of sensory organs.

15 capitulate the spatial pattern of peripheral sensory organs.

16 TRPML3 in the inner ear as well as in other sensory organs.

17 it is needed for the wing margin, veins, and sensory organs.

18 inciples might apply to development of other sensory organs.

19 ne organogenesis, notably the development of sensory organs.

20 late gustatory signaling in these peripheral sensory organs.

21 le for the formation and subtype identity of sensory organs.

22 adhesion processes in maintaining the amphid sensory organs.

23 innervate only one of six to eight distinct sensory organs.

24 fiable phenotypes only in auditory or ocular sensory organs.

25 nd generates the mirror-image pattern of the sensory organs.

26 at normally control the development of these sensory organs.

27 sion of Msx1, a marker of certain vestibular sensory organs.

28 rtility and development of the eye, wing and sensory organs.

29 the eye and cause defects in other external sensory organs.

30 ionship between hair and supporting cells in sensory organs.

31 ndefined sites, including different types of sensory organs.

32 o determine the developmental origins of the sensory organs.

33 s partial or complete loss of adult external sensory organs.

34 consisting of eight morphologically distinct sensory organs.

35 ed by adult legs with a diverse array of new sensory organs.

36 grees in hair cells of different species and sensory organs.

37 ervous system, maxillary cirri, and antennal sensory organs.

38 nvolves sensory acquisition via the relevant sensory organs.

39 time points of stimuli or their sampling by sensory organs.

40 velopment and are required for maturation of sensory organs.

41 d bigger LLP, affecting the final pattern of sensory organs.

42 connective tissues, whereas placodes produce sensory organs.

43 tion and cell fate determination of external sensory organs.

44 s requirement for the pigmentation of larval sensory organs.

45 mAnkrd6 causes PCP defects in the inner ear sensory organs.

46 information for their progression to mature sensory organs.

47 is highly expressed in the retina and other sensory organs.

48 on of hair cell function within the auditory sensory organ, a mechanism thought to modulate the dynam

49 lan of the cephalopods with highly developed sensory organs, a complex central nervous system, and co

50 utants known to affect the function of these sensory organs also interfere with temperature synchroni

51 , a gene with a deeply conserved function in sensory organ and appendage development, in the sex comb

52 scheme, in which the interaction between the sensory organ and the environment is not affected by its

53 for the nematode, which utilizes specialized sensory organs and a chemoreceptor that is tuned to reco

54 uca sexta are supplied by a diverse array of sensory organs and associated neurons that differ from t

55 The formation of the sensory organs and cells that make up the peripheral ner

56 ened head ectoderm that contribute to paired sensory organs and cranial ganglia.

57 atterned feed-forward excitation provided by sensory organs and experience drives the formation of ma

58 prediction based on a proposal that the ear sensory organs and fly mechanosensory organs are evoluti

59 (the common precursor region of many cranial sensory organs and ganglia), and other ectodermal domain

60 tant roles during the development of cranial sensory organs and ganglia, kidneys, hypaxial muscles an

61 to placodes and ultimately into many cranial sensory organs and ganglia.

62 from the dorsolateral ectoderm: chordotonal sensory organs and non-neural oenocytes.

63 inner ear, Bmp4 expression persists in some sensory organs and restricted domains of the semicircula

64 They contribute to the paired sensory organs and the cranial sensory ganglia generatin

65 Our work has shown that sensory organs and the endolymphatic duct each arise nea

66 within the otic placode confers identity to sensory organs and to the corresponding otic neurons.

67 Inner ear sensory organs and VIIIth cranial ganglion neurons of th

68 mulation of EVs in the lumen of the cephalic sensory organ, and failure to release PKD-2::GFP-contain

69 We propose that most Drosophila sensory organs are built from an archetypal lineage, and

70 Sensory organs are composed of neurons, which convert en

71 the levels of Scute are limiting, then some sensory organs are missing in achaete mutant flies.

72 Furthermore, aberrant and ectopic sensory organs are observed; most striking among these i

73 Sensory organs are often composed of neuronal sensory en

74 Sensory organs are specialized to detect and decode stim

75 Unraveling how these sensory organs are specified during development is key t

76 Essential to the operation of these sensory organs are the biomineralized structures--otocon

77 Although the morphology and function of the sensory organs are well characterized, their origins and

78 These results suggest that a single sensory organ arises from cells in different parts of th

79 om the biological clock and from a metabolic sensory organ as the arcuate nucleus, are essential for

80 expression may presage the differences among sensory organs as they arise from this sensory competent

81 direct upstream regulators of Fgf10 in this sensory organ, as part of constructing the programme of

82 All presumptive sensory organs, as identified by Bmp4 expression, arose

83 romast can break morphologic symmetry of the sensory organ at the stereocilia tips.

84 ls were killed and the peripheral vestibular sensory organs, brainstem, and cerebellum were collected

85 , ectopic scute expression produces external sensory organs but not chordotonal organs in the wing.

86 cas show specific transformations in mechano-sensory organ cell identity, characteristic of mutations

87 correct specification of individual external sensory organ cells involves not only cut, but also the

88 adult external sensory organs or subsets of sensory organ cells.

89 trically localized in cells of the inner ear sensory organs, characteristic of components of conserve

90 L4) is thought to be the main route by which sensory organs communicate with cortex.

91 brain size reduction, because the brain and sensory organs complete their growth before the rest of

92 The Drosophila adult external sensory organ, comprising a neuron and its support cells

93 sec15(-) sensory organs contain extra neurons at the expense of s

94 Sensory organ damage induces a host of cellular and phys

95 he human SIFD syndrome, including anemia and sensory organ defects.

96 medial ventral ray, does not have increased sensory organ density, and we describe these findings in

97 Vertebrate craniofacial sensory organs derive from ectodermal placodes early in

98 nals, saccule, utricle, and their associated sensory organs, detects angular and linear acceleration

99 To understand the molecular basis of sensory organ development and disease, we have cloned an

100 that Drosophila Insensitive (Insv) promotes sensory organ development and has activity as a nuclear

101 positively regulates Notch signaling during sensory organ development but acts negatively on Notch t

102 s localization, function, and how it impacts sensory organ development in vivo is not known.

103 Sensory organ development is also markedly disrupted in

104 d to affect asymmetric cell divisions during sensory organ development, carry lgl deletions that are

105 be upstream of very early events during the sensory organ development, hair cell differentiation and

106 To identify molecules involved in sensory organ development, we conducted a tissue-specifi

107 into Wnt-responsive progenitor cells during sensory organ development.

108 with cell fate specification during eye and sensory organ development.

109 dy the basis of Eya1 dosage requirements for sensory organ development.

110 higher vertebrates has an additional role in sensory organ development.

111 t to inhibit Notch signaling and specify fly sensory organ development.

112 icular bristles on T3 at different points in sensory organ development.

113 enes involved in the constructive changes in sensory organ development.

114 in multiple cell fate decisions during adult sensory organ development.

115 In flies, overexpression of Atx-1 inhibits sensory-organ development by decreasing Senseless protei

116 DAF-6/patched-related site of action during sensory-organ development.

117 ndary, although their expression patterns in sensory organs differ.

118 sequent activation of Fgf signaling controls sensory organ differentiation, but not progenitor prolif

119 provide the first molecular evidence whereby sensory organs direct the development of the associated

120 In vertebrates, the inner ear sensory organs display distinctive forms of PCP.

121 cience but has not been adapted to the taste sensory organ due to anatomical constraint.

122 gene is widely expressed in placode-derived sensory organs during embryogenesis but Eya1 function ap

123 ES ion transport cells relative to inner ear sensory organs, dysplasia of the endolymph fluid space,

124 Here we report the discovery of a sensory organ embedded within the fibrous symphysis betw

125 The repair of sensory organs enables animals to continuously detect en

126 ation of either mechanosensory or structural sensory organ epithelia.

127 e role of the TSC in the Drosophila external sensory organ (ESO), a classic model of asymmetric cell

128 e C. elegans male tail constitute a compound sensory organ essential for mating.

129 ir-279/996 cluster, with a majority of notum sensory organs exhibiting transformation of sheath cells

130 Within these sensory organs, expression of the transcription factor E

131 the ancestral-like coding sequences rescued sensory organ fate in atonal mutants, in contrast to non

132 ner of a selector gene to control neural and sensory organ fate specification in the otocyst.

133 veloped mature nerve terminals and epidermal sensory organs first; also, in developing cortex, marker

134 The carotid body is a sensory organ for detecting arterial blood O2 levels and

135 cochlea and the vestibule, is a specialized sensory organ for hearing and balance.

136 Carotid bodies, the sensory organs for detecting arterial oxygen, express 5-

137 In Drosophila, candidate sensory organs for detecting the gravity vector were pre

138 e halteres of dipteran insects are essential sensory organs for flight control.

139 In chickens, the sensory organs for taste are the taste buds in the oral

140 ermal cells causes induction of PNS external sensory organ formation and is able to recreate an ectop

141 ination and migration of neural cells during sensory organ formation in the spider.

142 ergize with proneural proteins and to induce sensory organ formation in vivo.

143 (OV), resulting in the failure of inner ear sensory organ formation, and in duplication of the cochl

144 neurogenesis and tissue specification during sensory organ formation.

145 al line placodes, which exhibit two modes of sensory organ formation: elongation to form sensory ridg

146 The Drosophila external sensory organ forms in a lineage elaborating from a sing

147 at glia are required for multiple aspects of sensory organ function.

148 e involved in patterning or specification of sensory organs, ganglion cells and hair cell mechanorece

149 Insect sensory organs have been a favorable model system for in

150 tic responsiveness highlight how the primary sensory organs have been optimized and can be modulated

151 ne cut is a hierarchal regulator of external sensory organ identity and is required to pattern the se

152 Previously, we have shown that each sensory organ in the chicken inner ear arises independen

153 In particular, the auditory sensory organ in the cochlea, adorned with precisely pat

154 aining isoforms and transforms the fate of a sensory organ in the male tail.

155 ion of the past 5 years is that very diverse sensory organs in Drosophila are produced by astonishing

156 correct identity of external (bristle-type) sensory organs in Drosophila.

157 and investigate its role in the formation of sensory organs in mammal and fish model organisms.

158 tions of taste cells in peripheral gustatory sensory organs in mice.

159 rate Gsk3-beta) regulates the development of sensory organs in the anterior-dorsal quadrant of the wi

160 ateral induction produces misshapen or fused sensory organs in the chick.

161 alised areas of ectoderm that contributed to sensory organs in the common ancestor of vertebrates and

162 iliated sensory neurons located primarily in sensory organs in the head and tail.

163 lt-related participate in the development of sensory organs in the thorax, mainly in the positioning

164 The maintenance of taste sensory organs in the tongue was shown 140 years ago to

165 Specialized sensory organs in the vertebrate head originate from thi

166 Cranial placodes, which give rise to sensory organs in the vertebrate head, are important emb

167 and the self-organization of rosette-shaped sensory organs in the zebrafish lateral line system.

168 Our results indicate that in certain sensory organs, in which the requirement to transduce sp

169 This unique sensory organ includes taste buds, papilla epithelium an

170 focused on the nervous system and associated sensory organs including the olfactory organ, retina, le

171 region often gives rise to cells in multiple sensory organs, including cells that apparently disperse

172 Diverse sensory organs, including mammalian taste buds and insec

173 A widely-accepted assumption is that the sensory organ is the first station in a serial chain of

174 Input from the sensory organs is required to pattern neurons into topog

175 ce in the Drosophila melanogaster peripheral sensory organ lineage is controlled by the non-neuronall

176 proneural transcription factor Achaete, and sensory organ loss caused by Amun overexpression can be

177 e expression of Bmp4 with two other putative sensory organ markers, Lunatic Fringe (L-fng) and chicke

178 cal labial palpomeres with dense specialized sensory organs, match those of modern taxa and suggest t

179 a major excitatory neurotransmitter in other sensory organs, might act at synapses in taste buds.

180 per patterning of gene expression related to sensory organ morphogenesis (Otx1 and Bmp4, respectively

181 iption and the control of cell number during sensory organ morphogenesis.

182 ne primordium (pLLP) generates the zebrafish sensory organs (neuromasts, NMs).

183 In the head, terminal sensory organ neurons showed increased activity in respo

184 As plants have neither specialized sensory organs nor a nervous system, intercellular regul

185 The semicircular duct system is part of the sensory organ of balance and essential for navigation an

186 seous labyrinth, which houses the vestibular sensory organ of balance and orientation [4].

187 The main sensory organ of Caenorhabditis elegans, the amphid, pro

188 e ablated the sheath glial cell of the major sensory organ of Caenorhabditis elegans.

189 reparation of the rat vestibular crista, the sensory organ of the semicircular canals that sense head

190 derlie glial morphological plasticity in the sensory organs of C. elegans.

191 ts among the cells that give rise to the ray sensory organs of Caenorhabditis elegans.

192 led serrano (sano) as being expressed in the sensory organs of Drosophila larvae.

193 The sensory organs of the avian ear are able to regenerate h

194 The sensory organs of the Drosophila adult leg provide a sim

195 beta (TGF-beta) family, is expressed in all sensory organs of the frog inner ear, as it is in the de

196 ng axon, conveys information received by the sensory organs of the front contralateral leg to the neu

197 ion of SoxC genes in vivo results in stunted sensory organs of the inner ear and loss of hair cells.

198 The mechanisms of formation of the distinct sensory organs of the inner ear and the non-sensory doma

199 single sensory competent zone from which all sensory organs of the inner ear develop.

200 Notably, vestibular sensory organs of the inner ear, the maculae, exhibit a

201 tic placode and otocyst can give rise to the sensory organs of the inner ear, though there were diffe

202 4 also guide the migration of germ cells and sensory organs of the lateral line.

203 re I show that crocodilians have specialized sensory organs on their faces that can detect small disr

204 a passive relay station of information from sensory organs or subcortical structures to the cortex.

205 h increased numbers of entire adult external sensory organs or subsets of sensory organ cells.

206 nto the molecular mechanisms involved in leg sensory organ patterning, we have analyzed a Hedgehog (H

207 nosensory bristles, Delta (Dl) ligand in the sensory organ precursor (SOP) cell is targeted for ubiqu

208 he lateral inhibition process by which adult sensory organ precursor (SOP) cells are specified, but t

209 uring peripheral neurogenesis in Drosophila, sensory organ precursor (SOP) cells arise within proneur

210 increased production of sensory bristles and sensory organ precursor (SOP) cells on the notum of some

211 roneural gene specifies different numbers of sensory organ precursor (SOP) cells within distinct regi

212 l neurogenesis, Notch controls cell fates in sensory organ precursor (SOP) cells.

213 symmetric segregation of determinants in the sensory organ precursor (SOP) lineage.

214 During sensory organ precursor (SOP) specification, a single ce

215 From the PNC, a single cell, the sensory organ precursor (SOP), is selected as the adult

216 ise through asymmetric divisions of a single sensory organ precursor (SOP).

217 During Drosophila sensory organ precursor cell development, Numb segregate

218 In normal development, the sensory organ precursor cell divides asymmetrically thro

219 at this is indeed the case in the Drosophila sensory organ precursor cell lineage.

220 eby EGF secretion from a subset of abdominal sensory organ precursor cells (SOPs) to induce an approp

221 ling techniques to follow Notch receptors in sensory organ precursor cells in Drosophila.

222 embrane and reveal a novel morphology to the sensory organ precursor cells of wing imaginal discs.

223 In Drosophila sensory organ precursor cells, the localization of Numb

224 cell morphology, and the differentiation of sensory organ precursor cells.

225 REAM/MMB, DMyb promotes the PCD of specified sensory organ precursor daughter cells in at least two d

226 During sensory organ precursor divisions in Drosophila, the num

227 d is important for alpha-Ada function in the sensory organ precursor lineage, it was dispensable in t

228 mechanism), is restricted to anterior-dorsal sensory organ precursors (SOP) expressing Senseless (Sen

229 ingers that is expressed and required in the sensory organ precursors (SOP) for proper proneural gene

230 eural gene specifies a stereotypic number of sensory organ precursors (SOP) within each body segment

231 Sensory organ precursors (SOPs) also segregate Numb asym

232 In the developing wing disc, single sensory organ precursors (SOPs) are selected from proneu

233 Asymmetric division of sensory organ precursors (SOPs) in Drosophila generates

234 In Drosophila sensory organ precursors (SOPs), the core PCP components

235 ervous system leads to ectopic production of sensory organ precursors (SOPs), whereas overexpression

236 elix (bHLH) proneural proteins in Drosophila sensory organ precursors and is required for their norma

237 tial Hedgehog pathway activity in peripheral sensory organ precursors creates ORN populations with di

238 Strikingly, ectopic Insv fully rescued sensory organ precursors in Hairless null clones, indica

239 comprise the "proneural clusters" from which sensory organ precursors of the peripheral nervous syste

240 Hedgehog signaling in the imaginal sensory organ precursors thus confers differential ORN r

241 separate subareas, creating six of the eight sensory organs present in birds.

242 from the leg epithelium, rather than single sensory organ progenitors.

243 Peripheral sensory organs provide the first transformation of senso

244 Efferent feedback onto sensory organs provides a means to modulate input to the

245 by the information our eyes/retina and other sensory organs receive from the outside world, but stron

246 powerful paradigm to mechanistically dissect sensory organ regeneration.

247 od step toward physiological recovery during sensory-organ regeneration.

248 uer, in which glia and neurons of the amphid sensory organ remodel.

249 hat lumen formation in the C. elegans amphid sensory organ requires the gene daf-6.

250 Patterning of sensory organs requires precise regulation of neural ind

251 al and kinematic evidence indicate that this sensory organ responds to both the dynamic rotation of t

252 ersely Lmx1a (or cLmx1b in the chick) allows sensory organ segregation by antagonizing lateral induct

253 hterless are sufficient to generate thoracic sensory organs (SOs) in the absence of achaete-scute gen

254 The inner ear, which contains the sensory organs specialised for audition and balance, dev

255 The inner ear, which contains sensory organs specialized for hearing and balance, deve

256 In many sensory organs, specialized receptors are strategically

257 Among these, we identified a polycistronic, sensory organ-specific paralogous miRNA cluster that inc

258 We show that A2BP1 regulates sensory organ specification by potentiating Notch signal

259 , including eye patterning, wing margin, and sensory organ specification defects.

260 We find that Cut is required for wing-margin sensory organ specification in addition to and independe

261 ibition processes in the embryonic mesoderm, sensory organ specification in imaginal discs and cell t

262 cells of the proneural cluster orchestrates sensory organ specification.

263 s (much like numerosity maps) do not reflect sensory organ structure but instead emerge within the br

264 Finally, the precursors of peripheral sensory organs such as the ear and olfactory placode und

265 omplex contains proneural genes for external sensory organs such as the macrochaetae, large sensory b

266 The saccule is a vestibular sensory organ that depends upon regulation of its lumina

267 licated in O2 sensing by the carotid body, a sensory organ that monitors arterial blood O2 levels and

268 for the formation of muscle spindle fibers, sensory organs that are distinct from skeletal muscle co

269 the integration of motion cues from multiple sensory organs that individually do not provide an accur

270 ates, containing a group of mechanosensitive sensory organs that mediate hearing and balance.

271 ode into a labyrinth of chambers which house sensory organs that sense sound and are used to maintain

272 plex, consisting of fluid-filled tubules and sensory organs that subserve the functions of hearing an

273 r duct houses both a vestibular and auditory sensory organ (the lagena macula and basilar papilla, re

274 The auditory sensory organ, the cochlea, not only detects but also ge

275 osensory lineage reconstruction of a complex sensory organ, the inner ear, by imaging zebrafish embry

276 region that gives rise to both the auditory sensory organ, the organ of Corti, and SG neurons.

277 The mammalian auditory sensory organ, the organ of Corti, consists of sensory h

278 fferentiation and patterning of the auditory sensory organ, the Usher complex, and the planar cell po

279 structural sexual dimorphism in a peripheral sensory organ, the VNO.

280 of a neural prosthesis that can substitute a sensory organ: they bypass the malfunctioning auditory p

281 ied the olfactory Grueneberg ganglion as the sensory organ through which mammalian alarm pheromones s

282 coordinately oriented within each inner ear sensory organ to exhibit a particular form of planar cel

283 tures are the filopodia, which act like cell sensory organs to communicate with the extracellular mic

284 n supposed that microvilli on T cells act as sensory organs to enable search, but their strategy has

285 scription factors are required for different sensory organs to form.

286 Neural pathways projecting from sensory organs to higher brain centers form topographic

287 roup of migrating epithelial cells that form sensory organs, to understand how tissue growth is contr

288 st T cells, they can thus be considered as a sensory organ, trained on self-peptide-MHCs and primed t

289 Our sensory organs transduce errors in behavior.

290 The skin is our largest sensory organ, transmitting pain, temperature, itch, and

291 Proneural genes thus appear to specify the sensory organ type.

292 maintain coherent synaptic transmission from sensory organs undergoing frequent variations in the num

293 specifically in the socket cell of external sensory organs, via an autoregulatory enhancer called th

294 None of the other seven sensory organs was related to the ganglion neurons, sugg

295 As a model for a magnetic sensory organ we propose a system of radical pairs being

296 To decipher glial roles in sensory organs, we ablated the sheath glial cell of the

297 es with Cut in the support cells of external sensory organs, which secrete the bristle shaft and sock

298 he development of the cranium and associated sensory organs, which were crucial for the evolution of

299 The whisker system is an important sensory organ with extensive neural representations in t

300 Contact of developing sensory organs with the external environment is establis