ライフサイエンスコーパス: septal

1 h a significantly lower systolic velocity S' septal (7.6+/-1.2 versus 8.5+/-1.2 cm/s, P=0.003) by tis

2 ents with PPCM had lower early velocities E' septal (9.9+/-2.1 versus 11.0+/-1.5 cm/s, P=0.02), with

3 enty years after the introduction of alcohol septal ablation (ASA) for the treatment of obstructive h

4 ous data on septal myectomy (SM) and alcohol septal ablation (ASA) in obstructive hypertrophic cardio

5 clinical outcome and survival after alcohol septal ablation (ASA) in patient with hypertrophic cardi

6 However, the results of alcohol septal ablation are dependent on the septal perforator a

7 ardial infarction (PMI), patients undergoing septal ablation for hypertrophic cardiomyopathy.

8 Alcohol septal ablation is a less invasive treatment.

9 eptal reduction therapy (myectomy or alcohol septal ablation) is recommended.

10 43 days) after surgical myectomy (or alcohol septal ablation), 92% and 95% of patients with or withou

11 choice between surgical myectomy and alcohol septal ablation.

12 , either surgical septal myectomy or alcohol septal ablation.

13 congenital heart defects, including cardiac septal abnormalities, but our understanding of the contr

14 lly released acetylcholine (ACh) from medial septal afferents activates muscarinic receptors on both

15 proteins to samples from patients undergoing septal alcohol ablation for hypertrophic cardiomyopathy,

16 Grasping the septal and anterior leaflets allowed for the best post-p

17 the septum; in turn, EBGNs were targeted by septal and entorhinal inputs.

18 -20.6 [-19.0 to -22.5]%; P=0.0098), as were septal and free-wall segments.

19 ence limits for TDI e' (4.6 and 5.2 cm/s for septal and lateral TDI e', respectively) were substantia

20 Regarding location and pattern, septal and midwall LGE showed strongest associations wit

21 proposed as molecular switches that balance septal and peripheral (side-wall like) peptidoglycan (PG

22 Septal and posterior grasping induced a significant reco

23 tricular posterior wall and interventricular septal and relative wall thicknesses (all P<0.05), reduc

24 de tracers into medial septum, or triangular septal and septofimbrial nuclei, revealed fibers descend

25 as having abnormal LV mass index, relative, septal, and posterior wall thickness, respectively.

26 attributed to PFO with an associated atrial septal aneurysm or large interatrial shunt, the rate of

27 attributed to PFO, with an associated atrial septal aneurysm or large interatrial shunt, to transcath

28 ware of imaging findings of interventricular septal aneurysm, because of its rarity of occurrence and

29 ware of imaging findings of interventricular septal aneurysm, because of its rarity of occurrence, co

30 lar stroke volume, isovolumic relaxation, E' septal annulus, E/E' septal annulus, left ventricular di

31 ovolumic relaxation, E' septal annulus, E/E' septal annulus, left ventricular diastolic volume).

32 entricular reentrant tachycardia mediated by septal AP (P<0.001; sensitivity 98%; specificity 93%; po

33 entricular reentrant tachycardia mediated by septal APs.

34 R5 knock-out (KO) neurons were placed in the septal area, the cell-sparse region separating barrels.

35 d to deliver 1 to 4 cc of 98% ethanol into a septal branch of the anterior interventricular vein in 5

36 patients with left ventricular summit VT, a septal branch of the middle cardiac vein, and a posterol

37 We hypothesized that septal branches generate disturbed flow in the LAD and P

38 the OFT, 2 processes that are essential for septal bridge formation.

39 %), papillary muscle (n=3; 3.1%), and apical-septal bundle (n=1; 1.0%), as well as imaging plane obli

40 and 16 pulmonary valvuloplasties, 37 atrial septal cases, and 6 unclassified cases.

41 ng oxidative stress levels, and iv) alveolar septal cell apoptosis.

42 powered by GTP hydrolysis and guides correct septal cell wall synthesis and cell division.

43 namics direct the processive movement of the septal cell wall synthesis machinery but do not limit th

44 g provides a mechanism for achieving uniform septal cell wall synthesis to enable correct polar morph

45 dinating an ensemble of proteins involved in septal cell wall synthesis to ensure successful constric

46 ecular composition and ultrastructure of the septal cell wall were substantially altered.

47 The septal cells stained for vesicular acetylcholine transpo

48 Both the number of septal cells with cholinergic phenotype and their densit

49 epletion of GpsB prevents PBP2x migration to septal centers.

50 he total number, density, and soma volume of septal cholinergic cells, which were visualized in brain

51 sense the wakefulness-dependent activity of septal cholinergic fibers through the alpha7-nicotinic a

52 while modulating the excitability of medial septal cholinergic neurones.

53 ajority of local GABAergic and a minority of septal cholinergic neurons.

54 Modifying septal cholinergic tone in this way also led mice to exh

55 MS-DBB glutamatergic neurons modulate local septal circuits, which in turn contribute to theta rhyth

56 ith ATTR (70% sigmoid septum and 30% reverse septal contour), whereas symmetrical LVH was present in

57 ross-linking) is restricted spatially to the septal cross-wall and temporally to cell division.

58 aOR = 1.28; 95% CI: 1.03, 1.61), ventricular septal defect (aOR = 1.19; 95% CI: 1.00, 1.43), and tetr

59 sitively associated with the risks of atrial septal defect (aORs ranging from 1.29 to 2.17), patent d

60 offspring with a perimembranous ventricular septal defect (odds ratio = 3.23, 95% confidence interva

61 eft superior vena cava (P=0.85), ventricular septal defect (P=0.12), and bicuspid aortic valve (P=0.1

62 erved an increased risk of CHDs, ventricular septal defect (VSD), and tetralogy of fallot (TF) with i

63 as identified with no associated ventricular septal defect (VSD).

64 omes after surgical closure of a ventricular septal defect (VSD).

65 to-right shunting in the form of ventricular septal defect and paradoxical thromboembolism.

66 Between 2008 and 2012, atrial septal defect closure with the AMPLATZER Septal Occluder

67 ventricular septum and TGA with ventricular septal defect performed from 2010 to 2013.

68 ents immediately prior to an elective atrial septal defect repair procedure.

69 Closure of atrial septal defect with the AMPLATZER Septal Occluder is safe

70 tidiastole of coronary heart disease, atrial septal defect, and atrial fibrillation are made, and the

71 ients (6%) in the pitavastatin group (atrial septal defect, chronic obstructive pulmonary disease, ch

72 y increased by the presence of a ventricular septal defect, left ventricular outflow obstruction, sur

73 urgery for atrial septal defect, ventricular septal defect, tetralogy of Fallot, and transposition of

74 Sudden death after surgery for atrial septal defect, ventricular septal defect, tetralogy of F

75 onding to surgical closure of a large atrial septal defect.

76 eptum and 298 (38%) for TGA with ventricular septal defect.

77 pproaches for simple lesions, such as atrial septal defect.

78 association was significant for ventricular septal defects (1.1% vs 0.6%; P = .001) and other CHDs (

79 tricular septal defects (22/47, 47%), atrial septal defects (20/47, 43%), patent ductus arteriosus (1

80 rdiovascular anomalies, of which ventricular septal defects (22/47, 47%), atrial septal defects (20/4

81 s (aRR, 0.85; 95% CI, 0.75-0.96), and atrial septal defects (aRR, 0.82; 95% CI, 0.69-0.95) but not se

82 (aRR, 0.77; 95% CI, 0.61-0.96), ventricular septal defects (aRR, 0.85; 95% CI, 0.75-0.96), and atria

83 Transcatheter closure of secundum atrial septal defects (ASD) using the Amplatzer septal occluder

84 Atrial septal defects (ASDs) are a common human congenital hear

85 dysregulation leads to development of atrial septal defects (ASDs) at high frequency.

86 de Lange syndrome-associated secundum atrial septal defects (ASDs) caused by NIPBL mutations, underta

87 Atrioventricular septal defects (AVSDs) are a common severe form of conge

88 Ventricular septal defects (VSDs) were associated with the highest b

89 fects within it, termed muscular ventricular septal defects (VSDs), are common, yet less is known abo

90 nt in magnitude were detected between atrial septal defects and bromoform (aOR = 1.56; 95% CI: 1.01,

91 diogenic transcription factor, cause cardiac septal defects and cardiomyopathy.

92 xclusively to Lipid II binding, which causes septal defects and catastrophic cell envelope damage.

93 , p.G115W, was identified in familial atrial septal defects and demonstrated decreased transactivatio

94 mutation in TLL1 was identified in an atrial septal defects kindred and is predicted to affect the en

95 Major ventricular septal defects were associated with larger HC relative t

96 X5, another transcription factor that causes septal defects when mutated.

97 odel a specific subtype of atrio-ventricular septal defects with exclusive ventricular shunting and d

98 erior cervical vertebral synostosis, cardiac septal defects with valve dysplasia, and deafness with i

99 % CI, -0.74 to -0.09); and major ventricular septal defects, -0.25 (95% CI, -0.35 to -0.15).

100 interval, -0.87 to -0.10); major ventricular septal defects, -0.41 (95% confidence interval, -0.52 to

101 9 kindreds with familial CHD, 4 with atrial septal defects, 2 with patent ductus arteriosus, 2 with

102 yndrome of progressive RCM, atrioventricular septal defects, and a high prevalence of atrial fibrilla

103 elopment, bicuspid aortic valve, ventricular septal defects, and embryonic lethality.

104 The associations with major ventricular septal defects, common arterial trunk, and anomalous pul

105 rged valve cusps, bicuspid aortic valve, and septal defects, indicating that endocardial Jag1 to Notc

106 rt chambers, interatrial or interventricular septal defects, pericardium, and site and size of the gr

107 uding abnormalities of other cardiac valves, septal defects, persistent left superior vena cava, and

108 c NSML SHP2 expression developed ventricular septal defects, suggesting that NSML-associated mutation

109 ased between 1990 and 2011 except for atrial septal defects, which increased significantly.

110 w tract alignment and membranous ventricular septal defects.

111 pecific defects, prevalence was greatest for septal defects.

112 for percutaneous closure of secundum atrial septal defects.

113 Septal deletion of mGluR5 abolished sociability while le

114 eroxia exposure inhibited alveolar-capillary septal development as evidenced by significantly increas

115 lateral maxillary sinusitis in patients with septal deviation (p=0.007).

116 Neither septal deviation (right sided: p=0.962; left-sided: p=0.

117 oncha bullosa and contralateral direction of septal deviation [right-sided (p=0.039), left-sided (p=0

118 study was to assess if the presence of nasal septal deviation and concha bullosa is connected with th

119 Nasal septal deviation was found in 79.9% of computed tomograp

120 Nasal septal deviation, contrary to concha bullosa, has influe

121 presence of concha bullosa and direction of septal deviation.

122 % [14%], P < .001), whereas interventricular septal diameter was higher (mean [SD], 16 [3] vs 14 [2]

123 tricular ejection fraction, interventricular septal diameter, mean limb lead QRS voltage, and grade 3

124 uration (</=7 h) had larger interventricular septal diastolic thickness, left ventricular (LV) end-di

125 verity of disease, causing cardiac valve and septal disease in the neonate that was similar to the ra

126 ed for StkP localization or FDAA labeling at septal division rings.

127 ty and inflow duration, mitral E' and E'/A', septal E' and A', pulmonary vein S and D wave velocities

128 icant relative improvement in GLS of 21% and septal e' of 24%.

129 olume (P<0.0001); and lower peak lateral and septal E' velocities (both P<0.01).

130 d by LV global longitudinal strain (GLS) and septal e' velocities, were compared before and after opt

131 c dimension z score of -1.85 or higher and a septal E' velocity z score less than -0.52 as having 74%

132 ecreased LV systolic, diastolic diameter, or septal E' velocity; higher ratio of LVWT to diastolic di

133 ; P<0.001), higher LAV (P<0.003), and longer septal electromechanical conduction time (P<0.01).

134 t, Panx1 knockout, and wild-type mouse nasal septal epithelial cells were grown at an air-liquid inte

135 roteins, exposed galactose on the surface of septal epithelial cells, thereby increasing its availabi

136 py confirmed unusual mineral deposits in the septal extracellular matrix of the mutant mice.

137 In all examined cortical regions, many septal GABAergic boutons were in close apposition to som

138 We report a specialized population of septal GABAergic neurons, the Teevra cells, selectively

139 In the CA1 region of hippocampus, septal GABAergic projections exclusively targeted intern

140 related with the increase in estimated trans-septal gradient (=pulmonary capillary wedge pressure-rig

141 ver from uniform lateral growth to localized septal growth is observed.

142 RI) was defined by lateral length divided by septal height.

143 e collected before transcoronary ablation of septal hypertrophy and at various times after transcoron

144 Severe septal hypertrophy before ASA remained a marker of reduc

145 inflammation after transcoronary ablation of septal hypertrophy, a procedure that mimics acute MI.

146 e hypertrophic cardiomyopathy (HCM) and mild septal hypertrophy, mitral valve (MV) abnormalities may

147 tract (LVOT) obstruction, but without basal septal hypertrophy, we sought to identify mitral valve (

148 ents and symptoms throughout the spectrum of septal hypertrophy.

149 matic patients with obstructive HCM and mild septal hypertrophy.

150 arious times after transcoronary ablation of septal hypertrophy.

151 (n=21) undergoing transcoronary ablation of septal hypertrophy.

152 d synaptophysin immunoreactivity, indicating septal inputs form synapses on NI neurons.

153 Medial septal inputs to the hippocampal system are crucial for

154 e target of GABAergic and cholinergic medial septal inputs.

155 to abolish all inducible VTs was because of septal intramural circuits or extensive right ventricula

156 ation between calcein transfer, SepJ-related septal junctions, and septal peptidoglycan nanopores.

157 oglycan perforations that likely accommodate septal junctions.

158 row as chains of cells that are connected by septal junctions.

159 eak longitudinal strain was obtained for the septal, lateral, anterior, and inferior myocardial walls

160 of anterior-posterior (-0.31 +/- 0.4 cm) and septal-lateral dimensions (-0.21 +/- 0.3 cm), a decrease

161 Unlike cardiac AL amyloidosis, asymmetrical septal left ventricular hypertrophy (LVH) was present in

162 cular activation wavefronts, particularly in septal locations and in patients without dense scar.

163 Left ventricular septal (LVS) pacing reduces ventricular dyssynchrony and

164 y which SpoIIQ specifically localizes to the septal membranes on the forespore side has remained enig

165 chored DNA translocase that localizes to the septal midpoint to mediate chromosome translocation and

166 val, 1.57-5.00; P=0.0005), and nonasymmetric septal morphology (odds ratio, 3.41; 95% confidence inte

167 olume, pulmonic outflow and interventricular septal motion may provide valuable insights into IUGR ca

168 Rhythmic medial septal (MS) GABAergic input coordinates cortical theta o

169 secondary MV chordae combined with a shallow septal muscular resection in severely symptomatic patien

170 3 (LC3)-II protein levels were higher in HCM septal myectomies than in nonfailing control hearts and

171 Previous data on septal myectomy (SM) and alcohol septal ablation (ASA) i

172 he perioperative mortality rate for isolated septal myectomy in most centers is <1%.

173 ed operators working in high-volume centers, septal myectomy is highly effective with a >90% relief o

174 A total of 2,107 septal myectomy operations performed in adults from Janu

175 th septal reduction therapy, either surgical septal myectomy or alcohol septal ablation.

176 dentified pre-operatively; in 1,830 (96.1%), septal myectomy was performed without a direct MV proced

177 9 patients, all of whom had MV surgery (with septal myectomy).

178 defibrillator placement, 5 valve surgery, 2 septal myectomy, 1 aortic arch replacement, 1 myocardial

179 After isolated septal myectomy, the percentage of patients with MR grad

180 women), judged as not optimal candidates for septal myectomy, were referred for management of severe,

181 pathy (HOCM) undergoing extended transaortic septal myectomy.

182 s with a clinical diagnosis of HCM underwent septal myectomy.

183 d clinical results are comparable to that of septal myectomy.

184 contouring the pericardium, selecting normal septal myocardium as a reference region, and then quanti

185 chronic pressure erosion of the intervening septal myocardium, leading to left-to-right shunting in

186 Oscillatory septal neuronal firing at delta, theta, and gamma freque

187 ion of cortical cells and regions by diverse septal neurons are unknown.

188 indicated that the majority of NI-projecting septal neurons were calretinin-positive and some were pa

189 theta generation through local modulation of septal neurons.

190 s, but the septohippocampal nucleus, lateral septal nuclei, amygdalostriatal transition area, bed nuc

191 was detected in the olfactory bulb, lateral septal nuclei, basal ganglia, and distinct areas of the

192 ical regions, hippocampus, amygdala, lateral septal nuclei, certain hypothalamic and midbrain nuclei,

193 d by the activation of nucleus accumbens and septal nuclei, structures expressing high levels of kapp

194 m including the septofimbrial and triangular septal nuclei.

195 d projection mapping showed that the lateral septal nucleus (LS) contained the densest accumulation o

196 decipher neural circuits emanating from the septal nucleus to the lateral hypothalamus (LH) that con

197 in the olfactory tubercle, striatum, medial septal nucleus, vertical and horizontal limbs of the dia

198 Medical after ASD closure with an Amplatzer septal occluder (cases) were compared with controls (mat

199 larger balloon-sized ASD diameter, Amplatzer septal occluder device size, and device size-ASD diamete

200 erosion after ASD closure with the Amplatzer septal occluder device.

201 ata on patients implanted with the AMPLATZER Septal Occluder for percutaneous closure of secundum atr

202 rm safety and effectiveness of the AMPLATZER Septal Occluder in clinical practice are not available.

203 ial septal defects (ASD) using the Amplatzer septal occluder is generally safe and effective, but ero

204 e of atrial septal defect with the AMPLATZER Septal Occluder is safe and effective.

205 ial septal defect closure with the AMPLATZER Septal Occluder was attempted in 1000 patients (aged 0.3

206 01), decreased peak E' velocity (lateral and septal P<0.001), and increased E/E' ratio (lateral and s

207 .001), and increased E/E' ratio (lateral and septal P<0.01).

208 LV volumes, stroke volume, stroke work, and septal peak systolic tissue velocity, and had more LV hy

209 ators with thick septa are required to limit septal penetration, at the cost of sensitivity and resol

210 N at the division site triggers synthesis of septal peptidoglycan and constriction of the cell envelo

211 transfer, SepJ-related septal junctions, and septal peptidoglycan nanopores.

212 tained an increased number of nanopores, the septal peptidoglycan perforations that likely accommodat

213 FtsA and the FtsBLQ subcomplex to de-repress septal peptidoglycan synthesis and membrane invagination

214 Loss of Ami1 resulted in defects in septal peptidoglycan turnover with release of excess cel

215 aments of FtsZ and FtsA (FtsAZ) that recruit septal peptidoglycan-synthesizing enzymes to the divisio

216 alcohol septal ablation are dependent on the septal perforator artery supplying the area of the conta

217 ower than in the LAD or RCA and there are no septal perforators with intramuscular courses like in th

218 e is that ASA is limited by the route of the septal perforators, whereas myectomy is not.

219 Accumulation of denuded glycans in the septal PG of both E. coli and B. subtilis, organisms sep

220 resent only transiently during biogenesis of septal PG provides a mechanism for coordinating the func

221 an, and that denuded glycans are enriched in septal PG rather than distributed uniformly around the s

222 we show that envelope machines facilitating septal PG synthesis (PBP1B-LpoB complex) and OM constric

223 The divisome controls septal PG synthesis and separation of daughter cells.

224 lly that SPOR domains localize by binding to septal PG, that the physiologically relevant binding sit

225 MreB localization to septal planes provides direct experimental observation f

226 n of MreB, which was restricted to predicted septal planes.

227 It forms a septal pore disc structure, recruits Spa18 and ApsB to s

228 lows directionally from cell to cell through septal pores.

229 l organism Anabaena sp. strain PCC 7120, the septal protein SepJ is required for filament integrity,

230 g the lateral septum (LS) is known to cause "septal rage," a phenotype characterized by a dramatic in

231 mean linear intercept, increased airspace-to-septal ratio, decreased nodal density, and decreased pul

232 eviewed, a total of 11248 patients underwent septal reduction procedures, of whom 6386 (56.8%) underw

233 ive analysis of patients undergoing surgical septal reduction strategies was conducted in 3 European

234 symptoms related to ventricular obstruction, septal reduction therapy (myectomy or alcohol septal abl

235 Use of septal reduction therapy and the effect of institutional

236 Both techniques of septal reduction therapy are highly operator dependent.

237 2003 through 2011, most centers that provide septal reduction therapy performed few SM and ASA proced

238 These patients can be treated with septal reduction therapy, either surgical septal myectom

239 ral of patients to centers of excellence for septal reduction therapy.

240 the subgenual cingulate cortex and adjacent septal region (SCSR) when experiencing self-blaming emot

241 prefrontal cortices, amygdala, hippocampus, septal region, and hypothalamus).

242 backbone of major projection pathways to the septal region, thalamus, hypothalamus, and brainstem, ea

243 s DamX, DedD, FtsN, and RlpA all localize to septal regions of purified PG sacculi obtained from E. c

244 rgic neurons neurons project to two distinct septal regions: the dorsal and intermediate region of th

245 Surgery in which the heart was opened (e.g., septal repair) versus surgery in which it was not (e.g.,

246 synthesis by PBP2b and positively regulates septal ring closure through its interactions with StkP-P

247 or depletion of GpsB prevents closure of the septal ring that in itself is PBP2x-dependent.

248 ought to be crucial for the formation of the septal ring, which is highly regulated in time and space

249 ude than 6-segment RVLS, 10+/-4% larger than septal RVLS, and 2+/-4% larger in women than in men (P<0

250 Basal septal scar and intramural VT origin makes VT ablation c

251 us 84% [interquartile range, 71%-87%]), with septal scars exhibiting the lowest concordance [(27% (in

252 f-SEP -82 to -99) compared with anterior and septal segments (-65 to -79), whereas the reverse patter

253 Ventricular septal sharpness (1/slope) was 165 for ECG pad and 152 f

254 Ventricular septal sharpness and signal-to-noise ratio were measured

255 PH patients demonstrated leftward septal shift and prolonged right ventricular systole, bo

256 , related to invasive hemodynamics, leftward septal shift, and prolonged right ventricular systole.

257 to adverse pulmonary hemodynamics, leftward septal shift, and prolonged right ventricular systole.

258 invasively determined PH severity, leftward septal shift, and prolonged right ventricular systole.

259 m, shared between ventricles and affected by septal shift, was the most affected LV region in PH.

260 One year after interatrial septal shunt device implantation, there were sustained i

261 n fraction patients 1 year after interatrial septal shunt device implantation.

262 s have demonstrated that a novel interatrial septal shunt device that allows shunting to reduce the l

263 d in the open-label study of the interatrial septal shunt device.

264 Septal signal-to-noise ratio on images generated by card

265 y the major autolysin LytA and occurs at the septal site.

266 s, but uncertainties remain, in part because septal-specific binding has yet to be studied in a purif

267 Peak systolic septal strain (20% versus 23%; P=<0.001) and midwall fra

268 ]% versus -21.1 [-19.1 to -23.0]%; P<0.0001) septal strain.

269 nferior-strain, -8.3% versus -9.9%; P<0.001; septal-strain, -9.1% versus -10.0%; P<0.001).

270 t echocardiography for selecting the correct septal (sub)branch; and 4) use of appropriate amounts of

271 selectively suppresses serotonin removal in septal subregions, whereas both fluoxetine and a dopamin

272 ical VT: 12.5%) was attributed to intramural septal substrate in 13 of 18 patients (72%).

273 eeding, aortic and mitral valve surgery, and septal surgery increased the odds of RAO.

274 ed treadmilling, the spatial distribution of septal synthesis and the molecular composition and ultra

275 hesis machinery but do not limit the rate of septal synthesis.

276 um of posterolateral systolic prestretch and septal systolic rebound stretch.

277 nge in T1 time was not significant (Baseline septal T1 1277.4 ms, follow up 1271.5 p = 0.504).

278 le range, 23-38 years) and more interlobular septal thickening and mediastinal lymphadenopathy on com

279 01), and greater relative wall thickness and septal thickness (both P<0.05); lower stroke volume (P<0

280 e assessed the influence of interventricular septal thickness (IVSd) on the clinical outcome and surv

281 z-score difference = -0.64; p = 0.01) as was septal thickness (z-score difference = -0.93; p = 0.001)

282 60% men; 57% on beta-blockers) with a basal septal thickness of </=1.8 cm who underwent echocardiogr

283 e patients with similar clinical profile and septal thickness that underwent isolated myectomy.

284 -exposed group, LV mass and LV end-diastolic septal thickness were lower whereas LV contractility and

285 ificant LV hypertrophy, in addition to basal septal thickness, anterior MV length, abnormal chordal a

286 edictors of maximal LVOT gradient were basal septal thickness, bifid PM mobility, anterior mitral lea

287 , LV end diastolic volume, relative wall and septal thickness, LV mass, and left atrial volume.

288 Mean basal septal thickness, LVOT gradient, and LV ejection fractio

289 gnetic resonance measurements included basal septal thickness, number/area of PM heads, and bifid PM

290 Mutant septal tips were stunted, lacked elastin-positive tips,

291 e rhythmicity of their firing decreases from septal to temporal termination of individual axons.

292 Mean septal-to-lateral and inter-trigone distances by 3D-TEE

293 RV mechanical synchrony improved: septal-to-lateral RV mechanical delay decreased (P<0.001

294 t chemogenetic and optogenetic activation of septal vesicular GABA transporter (vGAT)-containing neur

295 Consistently, chemogenetic inhibition of septal vGAT neurons increased food intake.

296 usly unknown neural circuit originating from septal vGAT neurons to a subset of vGAT neurons in the L

297 roposed to have a specific catalytic role in septal wall synthesis.

298 aphy demonstrated increased interventricular septal wall thickness (interventricular septum in diasto

299 raction, internal ventricular dimension, and septal wall thickness were not significantly different b

300 uides and regulates the inward growth of the septal wall.